• Wind and Structures
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• v.11 no.6
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• pp.497-512
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• 2008

In this paper, optimum methods of wind-induced vibration control of high-rise buildings are mainly studied. Two optimum methods, genetic algorithms (GA) method and Rayleigh damping method, are firstly employed and proposed to perform optimum study on wind-induced vibration control, six target functions are presented in GA method based on spectrum analysis. Structural optimum analysis programs are developed based on Matlab software to calculate wind-induced structural responses. A high-rise steel building with 20-storey is adopted and 22 kinds of control plans are employed to perform comparison analysis to validate the feasibility and validity of the optimum methods considered. The results show that the distributions of damping coefficients along structural height for mass proportional damping (MPD) systems and stiffness proportional damping (SPD) systems are entirely opposite. Damping systems of MPD and GAMPD (genetic algorithms and mass proportional damping) have the best performance of reducing structural wind-induced vibration response and are superior to other damping systems. Standard deviations of structural responses are influenced greatly by different target functions and the influence is increasing slightly when higher modes are considered, as shown fully in section 5. Therefore, the influence of higher modes should be considered when strict requirement of wind-induced vibration comfort is needed for some special structures.

• Journal of Microbiology and Biotechnology
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• v.23 no.6
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• pp.779-784
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• 2013

Leptospirosis is a worldwide zoonosis of global concern caused by Leptospira interrogans. The availability of ligand libraries has facilitated the search for novel drug targets using chemogenomics approaches, compared with the traditional method of drug discovery, which is time consuming and yields few leads with little intracellular information for guiding target selection. Recent subtractive genomics studies have revealed the putative drug targets in peptidoglycan biosynthesis pathways in Leptospira interrogans. Aligand library for the murD ligase enzyme in the peptidoglycan pathway has also been identified. Our approach in this research involves screening of the pre-existing ligand library of murD with related protein family members in the putative drug target assembly in the peptidoglycan biosynthesis pathway. A chemogenomics approach has been implemented here, which involves screening of known ligands of a protein family having analogous domain architecture for identification of leads for existing druggable protein family members. By means of this approach, one murC and one murF inhibitor were identified, providing a platform for developing an anti-leptospirosis drug targeting the peptidoglycan biosynthesis pathway. Given that the peptidoglycan biosynthesis pathway is exclusive to bacteria, the in silico identified mur ligase inhibitors are expected to be broad-spectrum Gram-negative inhibitors if synthesized and tested in in vitro and in vivo assays.

• Asian Journal of Atmospheric Environment
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• v.11 no.1
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• pp.54-60
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• 2017

Quantifying the trace elements in infinitesimal ambient liquid samples (e.g., single raindrop, cloud/fog water, and the soluble fraction extracted from the particles collected for a short time) is an important task for understanding formation processes, heating/cooling rates, and their health hazards. The purpose of this study is to employ an in-air micro PIXE system for quantitative analysis of the trace elements in a thimbleful of reference liquid sample. The bag type liquid sample holder originally designed with $10{\mu}m$ thick $Mylar^{(R)}$ film retained the original shape without any film perforation and apparent peaks of film blank by the end of the analysis. As one of tasks to be solved, the homogeneity of the elemental distribution in liquid reference species was verified by the X-ray line profiles for several references. It was possible to resolve the significant peaks for whole target elements corresponding to the channel number of micro-PIXE spectrum. The calibration curves for the six target elements (Si, S, Cl, Fe, Ni, and Zn) in standard solutions were successfully plotted by concentration (ppm) and ROI of interest net counts/dose (nC).

• Steel and Composite Structures
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• v.4 no.6
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• pp.437-452
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• 2004

A simplified seismic design procedure for steel structures with buckling-restrained braces (BRB) was proposed based on the energy balance concept and the equal energy assumption. The input seismic energy was estimated from a design spectrum, and the elastic and hysteretic energy were computed using energy balance concept. The size of braces was determined so that the hysteretic energy demand was equal to the hysteretic energy dissipated by the BRB. The validity of using equivalent single-degree-of-freedom systems to estimate seismic input and hysteretic energy demand in multi story structures with BRB was investigated through time-history analysis. The story-wise distribution pattern of hysteretic energy demands was also obtained and was applied in the design process. According to analysis results, the maximum displacements of the 3-story structure designed in accordance with the proposed procedure generally coincided with the target displacements on the conservative side. The maximum displacements of the 6- and 8-story structures, however, turned out to be somewhat smaller than the target values due to the participation of higher vibration modes.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.1
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• pp.44-49
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• 2001

In this paper, we propose a new technique to compensate for the VCO nonlinearity using only the returned beat signal whose spectrum contains the internal reflections and the targets simultaneously. In the case of a distance measurement system using single antenna, the reflections from the circulator and the antenna are much larger than the return signal from target. The beat signal by these reflections is at much lower frequency than that of the target, and the VCO nonlinearity can be compensated for using these signals. Indoor experiments were carried out and the results show marked improvement in the shape of range profile and the range resolution.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.13 no.12
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• pp.2511-2517
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• 2009

Recently, a FMCW radar is used for the various purposes in the short range detection and tracking of targets. The main advantages of a FMCWradar are the comparative simplicity of implementation and the low peak power transmission characterizing the very low probability of signal interception. Since it uses the frequency modulated continuous wave for transmission and demodulation, the received beat frequency represents the range and Doppler information of targets. Detection and extraction of useful information from targets are performed in this beat frequency domain. Therefore, the resolution and accuracy in the estimation of a beat spectrum are very important. However, using the conventional FFT estimation method, the high resolution spectrum estimation with a low sidelobe level is not possible if the acquisition time is very short in receiving target echoes. This kind of problems deteriorates the detection performance of adjacent targets having the large magnitude differences in return echoes and also degrades the reliability of the extracted information. Therefore, in this paper, the model parameter estimation methods such as autoregressive and eigenvector spectrum estimation are applied to mitigate these problems. Also, simulation results are compared and analyzed for further improvement.

• Journal of the Korean Applied Science and Technology
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• v.39 no.6
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• pp.916-923
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• 2022

Water samples were collected from three spots(Namcheon, Changwoncheon and Cheongwoonji) in Changwon and genomic DNA was isolated from them. Quantitative PCR was performed with the isolated DNA as template and primers targeting five different class A extended-spectrum beta-lactamase(ESBL) genes(bla_OXA-1, bla_SHV, bla_TEM, bla_CTX-M-1, bla_CTX-M-9). The number of total ESBL genes from each sample showed large variations between each sample. Thirty nanograms of DNA from Namcheon contained 1.93×10⁶ copies of ESBL genes whereas the same amount of DNA from Changwoncheon contained 1.47×10⁵ copies of ESBL genes. However, the same amount of DNA from Cheongwoonji pond contained only 9.5×10³ copies of ESBL genes. The ratio of each ESBL genes showed little difference between Namcheon river and Changwoncheon river, but DNA from Cheongwoonji pond showed a large difference from the rest. bla_OXA-1 gene was present at 65.3%, and bla_CTX-M-1 gene 33.6% for Namcheon comprising together almost 99%. bla_OXA-1 gene was present at 64.1%, and bla_CTX-M-1 gene 19.1% for Changwoncheon comprising together over 83%. bla_CTX-M-1 gene was present at 87.5% and bla_CTX-M-9 genes 9.8% for Cheongwoonji, a pond which is a closed and isolated environment.

• Health Policy and Management
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• v.19 no.3
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• pp.1-26
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• 2009

Objectives : To identify target areas and set priorities among those areas identified for national quality evaluation. Methods : Target areas were identified from: i) analysis of the national health insurance claims data, mortality and prevalence data ii) various group surveys, including representatives from 22 medical specialty associations, 19 physician associations, QI staffs in hospital, civil organizations, and commissioners of Health Insurance Review and Assessment Service(HIRA) ⅲ) literature reviews and RAM(RAND/UCLA appropriateness method). The priority areas for national quality evaluation represented the full spectrum of health care and the entire life span. The criteria for selecting the priority areas were impact, improvability, and measurability. The priority areas were divided into three categories : short-term, mid-term, long-term. Results: Based on the group surveys and the data analysis, 46 candidates were selected as quality evaluation priority areas. 13 areas were selected as having a short-term priority areas: tuberculosis, community acquired pneumonia, stroke, ischaemic heart disease, diabetes, hypertension, chronic lower respiratory disease(asthma, chronic obstructive pulmonary disease), intensive care unit, emergency room, nosocomial infection, use of antibiotics, multiple medication and renal failure. This results suggested that we need to enlarge the target priority areas to the chronic diseases in short-term. Conclusions: The priority areas identified from the study will assist healthcare quality associated institutions as well as HIRA in selecting quality evaluation areas. It is required to develope and implement strategies for improving the quality of care within the next 5 years.

• Journal of the Society of Naval Architects of Korea
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• v.43 no.3 s.147
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• pp.384-391
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• 2006

RCS effects of long-crested wave surfaces to marine targets are numerically analyzed using a 4-path model and a direct analysis method, developed based on physical optics and a combined method of physical optics/geometric optics, respectively. Reflectivity of long-crested wave surfaces is described with 'Fresnel reflection coefficients' The MPM(modified Pierson-Moskowitz) ocean spectrum is adopted to simulate long-crested waves in the direct analysis method. A numerical analysis of a benchmark model assures the validity of both methods. The direct analysis method is applied to the RCS calculation of electromagnetically large marine targets, which are vertically oriented or slanted to the long crested wave surfaces randomly generated with various significant wave heights. The long-crested wave surface much highly increases the RCS of the marine target, but those effects are decreased as the significant wave height grows up. At low elevation angle, the vertical model has entirely high RCS comparing slanted model, and the RCS of vertical flat plate is the highest on the calm sea surface, while those of slanted flat plates are the lowest on the calm sea surface. The RCS of marine targets on continuously-varying sea surface is more coherent at lower elevation angles, as well.

• Journal of Advanced Navigation Technology
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• v.26 no.5
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• pp.350-357
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• 2022

With the recent prediction of 'Cycle 25', the importance of space weather research increases. Accordingly, the World Radiocommunication Conference (WRC)-23 has adopted Agenda Item 9.1a) and carried out sharing researches between active/passive space weather observation systems and existing services. Therefore, in this paper, in order to increase the precision of space weather environment data and secure the frequency spectrum for observation systems, the direct interference effect from the weather radar in Gosan, Jeju on the space weather observation receiver in Hallim, Jeju, and the indirect interference on the observation receiver by diffraction and scattering from the radar target have been analyzed. As a result, it can be known that the radar direction, the propagation direction diffracted and scattered from the target, and the Rradar Cross Section (RCS) of the radar target, the reception area of the space weather observation antenna, and the antenna off-boresight are important parameters for the interference effect analysis.