• Title/Summary/Keyword: Tailored treatments

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Clinical Experience of the Klippel-Trenaunay Syndrome

  • Sung, Hyung Min;Chung, Ho Yun;Lee, Seok Jong;Lee, Jong Min;Huh, Seung;Lee, Jeong Woo;Choi, Kang Young;Yang, Jung Dug;Cho, Byung Chae
    • Archives of Plastic Surgery
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    • v.42 no.5
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    • pp.552-558
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    • 2015
  • Background The Klippel-Trenaunay syndrome (KTS) is characterized by three clinical features, namely cutaneous capillary malformations, venous malformations, and soft tissue and/or bony hypertrophy of the extremities. The varied manifestations are attributed to the unpredictable clinical nature and prognosis of the syndrome. To elucidate the clinical characteristics of this disease, we reviewed a relatively large number of KTS patients who presented to our vascular anomalies center. Methods We conducted a retrospective study with 19 patients who were diagnosed with KTS and treated in our vascular anomalies clinic between 2003 and 2014, and examined their demographic characteristics, their clinical features, and the treatments administered. Results The sex distribution was balanced, with 9 (47%) males and 10 (53%) females. The mean follow-up period was 4.1 years (range, 7 months-9 years). Most of the patients received conservative treatments such as medication or physiotherapy. Compression therapies such as wearing of elastic garments/bandages were also administered, and surgical interventions were considered only when the patients became excessively symptomatic. Other treatments included laser therapy and sclerotherapy, and all the treatments were adjusted according to each case, tailored to the conditions of the individual patients. Conclusions KTS is an extremely rare, multifactorial disorder that induces widely varied symptoms. Because of this unique feature, plastic surgeons, when not careful, tend to attach a one-sided importance to typical symptoms such as limb hypertrophy or capillary malformation and thus overlook other symptoms and clinical features. KTS can be suspected in all infants who show capillary malformations or limb hypertrophy and require a multi-disciplinary approach for comprehensive management.

Exploratory Study of Factors Affecting Continuity of Cancer Care: Iranian Women's Perceptions

  • Fouladi, Nasrin;Ali-Mohammadi, Hossein;Pourfarzi, Farhad;Homaunfar, Nasrin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.133-137
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    • 2014
  • Background: Today, breast cancer is increasing in nearly all societies. Currently, cancers are the third leading cause of death in Iran after cardiovascular diseases and accidents. Of the cancers, breast cancer is spreading particularly rapidly among Iranian women. Negative effects of discontinuation of care on patient survival have been well documented. Inhibiting or facilitating factors affecting continuity of care at different stages of the patient care continuum should be identified. Materials and Methods: The current study implemented a qualitative method that provided tools to examine factors in detail. This study was conducted on 22 women, undergoing surgery and chemotherapy after being diagnosed with breast cancer. Content analysis was the technique adopted. Results: The effective factors in continuity of care from the patients' perception, based on the participant statements, were classified into three categories of evaluation of symptoms, psychological reactions, and care triggers with several subcategories. Conclusions: According to the outcomes of the current study, it can be noted that, the patient experiences can be brought into use by health-care professionals and assist them in providing patient sand their families with adequate consulting services. It can also provide an opportunity for making interventions tailored to the community culture, and closer adherence of patients to the prescribed treatments.

Effects of Process Parameters on Cell Control of Aluminum Foal Material (알루미늄 발포소재의 성형 공정 인자가 기공제어에 미치는 영향)

  • 전용필;강충길
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 1997.10a
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    • pp.163-166
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    • 1997
  • Aluminium foam material is a highly porous material having complicated cellular structure defined by randomly distributed air pores in metallic matrix. this structure gives the aluminium a set of properties which cannot be achieved by any of conventional treatments. The properties of aluminium foam material significantly depend on its porosity, so that a desired profile of properties can be tailored by changing the foam density. Melting method is the one of foaming processes, which the production has long been considered difficult to realize becaues of such problems as the low foamability of molten metal, the varying size of. cellular structures, solidification shrinkage and so on. These problems, however, have gradually been solved by researchers and some manufacturers are now producing foamed aluminum by their own methods. Most of all, the parameters of solving problem in electric furnace were stirring temperature, stirring velocity, foaming temper:iture, and so on. But it has not considered about those in induction heating, foaming velocity and foaming temperature in semi-solid state yet. Therefore, this paper presents the effects on these parameter to control cell size, quantity and distribution.

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New Helicobacter pylori Eradication Therapies (새로운 헬리코박터 제균 요법)

  • Park, Jae Yong;Kim, Jae Gyu
    • The Korean Journal of Gastroenterology
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    • v.72 no.5
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    • pp.237-244
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    • 2018
  • While the prevalence of Helicobacter pylori (H. pylori) infection is decreasing in Korea, the incidence of gastric cancer remains high, emphasizing the importance of H. pylori eradication. A new treatment strategy is needed as the eradication rate with standard triple therapy, which is currently the standard first-line regimen for H. pylori infection, has decreased below the optimum level. The major cause of eradication failure is increased antibiotic resistance. Sequential, concurrent, and hybrid therapies that include clarithromycin produce higher eradication rates than conventional standard triple therapy. However, the effectiveness of these treatments is limited in regions where the resistance rate to various antibiotics is high. Bismuth quadruple therapy is another alternative therapy, but again the eradication rate is not sufficiently high. Tailored therapy based on individual characteristics, including antibiotic susceptibility, may be ideal, but there are several limitations for clinical application and further research is needed. New potassium-competitive acid blocker-based therapies could emerge as effective alternatives in the near future. A consensus is needed to establish a strategy for applying new eradication therapies in Korea.

A Child Emotion Analysis System using Text Mining and Method for Constructing a Children's Emotion Dictionary (텍스트마이닝 기반 아동 감정 분석 시스템 및 아동용 감정 사전 구축 방안)

  • Young-Jun Park;Sun-Young Kim;Yo-Han Kim
    • The Journal of the Korea institute of electronic communication sciences
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    • v.19 no.3
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    • pp.545-550
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    • 2024
  • In a society undergoing rapid change, modern individuals are facing various stresses, and there's a noticeable increase in mental health treatments for children as well. For the psychological well-being of children, it's crucial to swiftly discern their emotional states. However, this proves challenging as young children often articulate their emotions using limited vocabulary. This paper aims to categorize children's psychological states into four emotions: depression, anxiety, loneliness, and aggression. We propose a method for constructing an emotion dictionary tailored for children based on assessments from child psychology experts.

Bilateral Checkrein Deformities of the Hallux Following Intramuscular Sarcoidosis: A Case Report (근육 내 사르코이드증 후 발생한 양측 무지의 체크레인 변형: 증례 보고)

  • Min Gyu Kyung;Sangyun Yun;Dong Yeon Lee
    • Journal of Korean Foot and Ankle Society
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    • v.28 no.2
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    • pp.71-74
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    • 2024
  • This report presents a unique case of checkrein deformities in both halluces following isolated intramuscular sarcoidosis, a rare occurrence given the infrequent musculoskeletal involvement in sarcoidosis. Typically resulting from flexor hallucis longus tendon entrapment by scar tissue post-trauma, the checkrein deformity reported in this paper presented with unusual metatarsophalangeal joint flexion and interphalangeal joint extension during ankle dorsiflexion. A 49-year-old woman with a history of intramuscular sarcoidosis presented with a great toe deformity and discomfort while wearing shoes, leading to a diagnosis of dynamic deformity, possibly attributed to tendon tethering by sarcoidosis. Surgical treatments, including abductor hallucis muscle intratendinous tenotomy, flexor hallucis longus Z-plasty lengthening, Weil osteotomy, and Kirschner wire fixation, significantly improved the functional scores and patient discomfort. This report underscores the importance of recognizing dynamic deformities and the potential for rare diseases, such as sarcoidosis, to cause such conditions, highlighting the need for careful diagnosis and tailored surgical intervention for atypical checkrein deformities.

A Study on Sports Injuries in Korean National Sitting Volleyball Players (국가대표 좌식배구 선수들의 운동상해 조사연구)

  • Chang-Ryeol Lee
    • Journal of the Korean Society of Physical Medicine
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    • v.19 no.2
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    • pp.107-122
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    • 2024
  • PURPOSE: This study examined sports injuries among national sitting volleyball players and to provide baseline data for the development of programs to prevent injuries and enhance performance. METHODS: The study surveyed 21 national team athletes (12 males and nine females) participating in the 4th Hangzhou Asian Para Games. The questionnaire consisted of 17 items, including general information, type of disability, sites and types of sports injuries and their causes, the current state of sports injuries and the treatment and management of injuries. RESULTS: The survey results suggested that the most common injury sites were the finger, shoulder, and waist. The most frequent types of injuries were sprain, muscle cramp, and LBP. The causes were insufficient warm-up, playing unhealed and carelessness. Injuries were most prevalent during morning training and in the winter. Most injuries occurred in practice, and the actions most likely to cause injuries were blocking, spike and sitting movements. Ice and spray were the most common treatments, usually administered by the athletes themselves. Physical therapy was the most common post-injury management, and the most common sequelae involved continuing to use despite pain. CONCLUSION: Based on these results, systematic and individualized training and therapeutic support tailored to the characteristics of sitting volleyball and the types of disabilities are necessary to prevent and manage sports injuries among national players. Continuous injury management by medical staff, particularly physical therapists, is essential to maintain the health of disabled athletes.

The Utility of Measuring Assimiliable Organic Carbon (AOC) as an Indicator of Biostability in Distribution Systems for Finished Water

  • Chang, Young-Cheol;Toyama, Tadashi;Jung, Kweon;Kikuchi, Shitaro
    • Journal of Environmental Health Sciences
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    • v.32 no.6
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    • pp.539-542
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    • 2006
  • The objective of this paper is to compare the applicability of assimilable organic carbon (AOC) or biodegradable dissolved organic carbon (BDOC) for quantifying biodegradable organic material (BOM) and bio-stability in distribution systems for a variety of finished waters. The study the data is derived from was part of an AWWARF and Tampa Bay Water tailored collaboration project to determine the effect of blending different waters on distribution system water quality. Seven different finished waters were produced from surface, ground, or brackish water on site and fed 18 independent pilot distribution systems (PDSs), either as single finished water or as a blend of several finished waters. AOC and BDOC have often been used as indicators of bacterial regrowth potential in distribution systems. In this study, AOC was the more useful assay of the two for the BOM concentrations observed in the PDSs. BDOC did not distinguish BOM while AOC did at the low BOM levels from many of the advanced treatments (e.g. RO, $O^3/BAC$). AOC in contrast allowed much more meaningful calculations of the consumption or production of AOC as the blends passed through the PDSs even for very low BOM blends. In addition, meaningful trends corresponding to changes in heterophic plate count (HPC) were observed for AOC but not for BDOC. Moreover, AOC stability was associated with waters produced from advanced membrane treatment.

Case Report: Reconstruction of the Lower Lip using the Karapandzic Flap (증례보고: Karapandzic Flap을 사용한 하순부 재건)

  • Jun Sik Kim;Jae Bong Shin;Nam Gyun Kim;Gi Cheol Do;Min Hyung Kim;Tae Ho Kim;Kyung Suk Lee
    • Korean Journal of Head & Neck Oncology
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    • v.39 no.2
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    • pp.75-78
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    • 2023
  • Squamous cell carcinoma of the lip is a common malignant tumor originating from oral cancer. However, unlike other areas, the lips hold significant functional and aesthetic importance as a part of the face. As a result, a tailored approach based on the tumor's size, type, and location is essential. The Karapandzic flap is especially suitable for reconstructing lesions located on the lip, particularly when the size of the cancer is large and other surgical treatments like free flaps are not feasible. It allows for extensive resection beyond the size of the lower lip. In this case, considering the patient's overall condition, successful reconstruction of the lower lip was achieved using the Karapandzic flap.

The Outcome of Long QT Syndrome, a Korean Single Center Study

  • Kyung Jin Ahn;Mi Kyoung Song;Sang Yun Lee;Ja Kyoung Yoon;Gi Beom Kim;Seil Oh;Eun Jung Bae
    • Korean Circulation Journal
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    • v.52 no.10
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    • pp.771-781
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    • 2022
  • Background and Objectives: Although long QT syndrome (LQTS) is a potentially life-threatening inherited cardiac channelopathy, studies documenting the long-term clinical data of Korean patients with LQTS are scarce. Methods: This retrospective cohort study included 105 patients with LQTS (48 women; 45.7%) from a single tertiary center. The clinical outcomes were analyzed for the rate of freedom from breakthrough cardiac events (BCEs), additional treatment needed, and death. Results: LQTS was diagnosed at a median age of 11 (range, 0.003-80) years. Genetic testing was performed on 90 patients (yield, 71.1%). The proportions of genetically confirmed patients with LQTS types 1, 2, 3, and others were 34.4%, 12.2%, 12.2%, and 12.2%, respectively. In the symptomatic group (n=70), aborted cardiac arrest was observed in 30% of the patients. Treatments included medications in 60 patients (85.7%), implantable cardioverter-defibrillators in 27 (38.6%; median age, 17 years; range, 2-79 years), and left cardiac sympathetic denervation surgery in 7 (10%; median age, 13 years; range, 2-34). The 10-year BCE-free survival rate was 73.2%. By genotype, significant differences were observed in BCEs despite medication (p<0.001). The 10-year BCE-free survival rate was the highest in patients with LQTS type 1 (81.8%) and the lowest in those with multiple LQTS-associated mutations (LQTM). All patients with LQTS survived, except for one patient who had LQTM. Conclusions: Good long-term outcomes can be achieved by using recently developed genetically tailored management strategies for patients with LQTS.