• Journal of Korean Tunnelling and Underground Space Association
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• v.17 no.6
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• pp.665-674
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• 2015

A TSL (Thin Spray-on Liner) which consists of polymers has a higher initial strength, faster construction time and higher waterproofing performance than the conventional cementitious shotcrete. Main supporting mechanism of TSL is the adhesion and tensile strength which is distinct from the conventional shotcrete. Even though highly in demand due to its outstanding characteristics, TSL is not yet well-known support material. In this study, to evaluate contact behavior of TSL, numerical analysis was performed with comparing result from laboratory tests. From the analysis, cohesive behavior at the contact surface between TSL and rock can be evaluated by using combination of cohesive and the damage model. In addition, results show that the cohesive stiffness controled slope between force and displacement, the fracture energy controled level of force at the contact.

• Archives of Pharmacal Research
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• v.16 no.2
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• pp.129-133
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• 1993

Temperature sensitive liposomes(TSL) containing adriamycin (ADM) and cytarabine (Ara-C) were prepared. ADM and Ara-C were selected as model compounds of amphiphilic and hydrophilic drug, respectively. Encapsulation efficiency of ADM entrapped into TSL was about twice greater than that of Ara-C. It might be due to different polarity of the drug, Lipid compositions of TSL had no effect on the encapsulation efficiency of drugs. Thermal behavior of TSL using a differential scanning calorimetry (DSC) was also investigated. Phase transition of TSL using a differential scanning calorimetry (DSC) was also investigated. Phase transition temperature $(T_c)$ of TSL was dependent on the lipid compositions of TSL ADM broadened thermogram of TSL but Ara-C did not. However, $T_c$ of TSL was not changed by any drug. Release rate of drugs was highly dependent on temperature. The release profile of ADM was similar to that of Ara-C. The maximum release rate of drugs from TSL was occurred at the near $T_c$ and observed at $39-41^\circ{C}$ for DPPC (Dipalmitoylphosphatidylcholine) only, $52-54^\circ{C}$ for DPPC and DSPC (1:1), respectively. Effect of human serum alburmin (HAA) on the release rate of ADM was investigated. HSA had no significant effect on the release of ADM below $T_c$. However, ADM release from TSL was increased at the near and above $T_c$. The HSA-induced leakage of drug may result from the interaction of liposomal constituents with HSA structure at the near TEX>$4^\circ{C}$. From the fact that the release profiles of ADM from freshly prepared TSL and stored TSL for 1 week at TEX>$4^\circ{C}$ was not changed, the TSL was considered to be stable for at least 1 week at TEX>$4^\circ{C}$. Based on these findings, TSL may be useful to deliver drugs to preheated target sites due to its thermal behaviors.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.176-176
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• 2023

The Tonle Sap is the richest and diverseness of freshwater ecosystem in Southeast Asia, receiving nurturing water flows from the Mekong and its immediate basin. In addition, the rapid development in the Tonle Sap Lake (TSL) Basin, and flood inundation may threaten the natural diversities and characteristics. The impacts of flood inundation in 11 sub-basins contributing to the Tonle Sap Lake were assessed using the Rainfall-Runoff-Inundation (RRI) model to quantify the potential magnitude and extent of the flooding. The RRI model is set up by using gauged rainfall data to simulate the information of river discharge and flood inundation of huge possible flood events. Moreover, two satellite precipitation products (SPPs), CHIRPS and GSMaP, within respectively spatial resolutions of 0.05° and 0.1°, are utilized as an input for the RRI model to simulate river discharge, flood depth, and flood extent for the great TSL Basin of Cambodia. This study used statistical indicators such as NSE, PBIAS, RSR, and R2 as crucial indices to evaluate the performance of the RRI model. Therefore, the findings of this study could provide promising guidance in hydrological modeling and the significant implications for flood risk management and disaster preparedness in the region.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.17 no.6
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• pp.668-672
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• 2004

Upon Debye's dielectric relaxation theory, we tried simple determination method of trap level in organic EL materials. From dielectric measurements in the 20 Hz - 1 MHz frequency range and in the 150 K - 320K temperature range, the depth of traps in Alq$_3$ filled with remaining electrons was determinated. Comparing to other determination techniques like TSL, or TL, the apparatus all we need is just simple LCR meter, thermometer and cooling method(liquid nitrogen). The mean activation energy is about 0.20 eV. It is in good agreement with previous determinations by other techniques like TSL. This results consolidate the validity of Burrow's transport mechanism model. Further intensified experiment with UV light on the dielectric absorption(Photodipolair effect) was nevertheless disturbed by the photoconductivity component.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.17 no.8
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• pp.757-765
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• 2007

Enhanced PSPICE circuit model for vented-box loudspeaker system with lumped parameters was proposed to more accurately simulate real vented-box loudspeaker system. Frequency dependent parameters were used to model voice coil inductor. Acoustic pressure response curves and electrical impedance curves were simulated and investigated by PSPICE circuit model according to circuit parameters' variations. Finally, it was used to identify faults detection in woofers manufactured by unskilled persons.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.17 no.10
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• pp.983-992
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• 2007

It was proposed to identify Thiele Small Parameters for loudspeaker attached to closed-box using known dynamic mass of moving parts. Also, enhanced PSPICE circuit model for closed-box loudspeaker system was proposed to more accurately simulate real closed-box loudspeaker system. Frequency dependent parameters were used to model voice coil inductor. Acoustic pressure response curves and electrical impedance curves were simulated and investigated by PSPICE circuit model according to compensation filter's parameters. Finally, proposed method is expected to be utilized for identification of pseudo Thiele Small parameters of microspeaker.

• 한국전산유체공학회:학술대회논문집
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• 2004.03a
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• pp.172-177
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• 2004

In the present work, we have interests on the modification of parallel implemented with MPI(Message Passing Interface) programming method, 3-Dimensional, unsteady, incompressible Navier-Stokes equation solver to analyze the low-Reynolds number flow In order to accurate calculation aerodynamic coefficients in low-Reynolds number flow field, we modified the two-equation turbulence model. This paper describes the development and validation of a new two-equation model for the prediction of flow transition. It is based on Mentor's low Reynolds $\kappa-\omega$ model with modifications to include Total Stresses Limitation (TSL) and Separation Transition Trigger (STT)

• Journal of the Korean Chemical Society
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• v.58 no.6
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• pp.575-579
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• 2014

Development of liposomes has been actively studied for effective delivery of drug at tumor site. However, despite their preferential accumulation at tumor site, the therapeutic efficacy of such liposomal drug has been limited because of low drug release. Therefore, we developed a temperature-sensitive liposome (TSL), which can be made to maximize release of drug by external stimulation such as ultrasound. Doxorubicin (DOX) as a model drug was encapsulated into TSL by a pH gradient method. The particle size of the TSL was $142.0{\pm}6.24nm$. Surface charge was $-10.55{\pm}1.12mV$. Release of drug from TSLs was up to 80% within 15 min at over $42^{\circ}C$ measured by fluorescence intensity. Cytotoxicity of released DOX from TSLs with ultrasound was highly increased compared to TSLs without ultrasound. Taken together, we demonstrate that temperature sensitive drug release from TSLs with ultrasound, which may be useful for cancer therapy to increase drug concentration at tumor site by external stimulation.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.103-104
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• 2015

본 논문에서는 모형 차량을 이용하여 자율주행 시스템을 구현하고자 한다. 이 시스템의 목적은 차선을 계속 유지함으로써 자율주행을 하는데 있다. 이를 위하여 32비트 마이크로프로세서를 이용한 모형차량을 설계하고 흰 바탕과 검은색 차선으로 이루어진 환경에서 시뮬레이션을 통해 살펴본다. 라인스캔 카메라(TSL1401CL)를 사용하여 차선을 인식하고 이에 따라 자율주행을 하는 시스템을 구현한다.

• 전자공학회논문지 IE
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• v.45 no.4
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• pp.60-67
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• 2008

Skin color is a very important information for an automatic face recognition. In this paper, we proposed a skin region extraction method using color information and skin color model. We use the adaptive lighting compensation technique for improved performance of skin region extraction. Also, using an preprocessing filter, normally large areas of easily distinct non skin pixels, are eliminated from further processing. And we use the modified ST color space, where undesired effects are reduced and the skin color distribution fits better than others color space. Experimental results show that the proposed method has better performance than the conventional methods, and reduces processing time by $35{\sim}40%$ on average.