• Asian-Australasian Journal of Animal Sciences
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• 제30권2호
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• pp.154-159
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• 2017

Objective: This study was designed to characterize the DNA polymorphisms of the melanocortin-1 receptor (MC1R) gene in indigenous Saudi Arabian sheep breeds exhibiting different color coats, along with individuals of the Sawaknee breed, an exotic sheep imported from Sudan. Methods: The complete coding region of MC1R gene including parts of 3' and 5' untranslated regions was amplified and sequenced from three the indigenous Saudi sheep; Najdi (generally black, n = 41), Naeimi (generally white with brown faces, n = 36) and Herri (generally white, n = 18), in addition to 13 Sawaknee sheep. Results: Five single nucleotide polymorphisms (SNPs) were detected in the MC1R gene: two led to nonsynonymous mutations (c.218 T>A, p.73 Met>Lys and c.361 G>A, p.121 Asp>Asn) and three led to synonymous mutations (c.429 C>T, p.143 Tyr>Tyr; c.600 T>G, p.200 Leu>Leu, and c.735 C>T, p.245 Ile>Ile). Based on these five SNPs, eight haplotypes representing MC1R $E^d$ and $E^+$ alleles were identified among the studied sheep breeds. The most common haplotype (H3) of the dominant $E^d$ allele was associated with either black or brown coat color in Najdi and Sawaknee sheep, respectively. Two other haplotypes (H6 and H7) of $E^d$ allele, with only the nonsynonymous mutation A218T, were detected for the first time in Saudi indigenous sheep. Conclusion: In addition to investigating the MC1R allelic variation in Saudi indigenous sheep populations, the present study supports the assumption that the two independent nonsynonymous Met73Lys and Asp121Asn mutations in MC1R gene are associated with black or red coat colors in sheep breeds.

• Toxicological Research
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• 제29권3호
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• pp.187-193
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• 2013

The effects of toluene in dimethylformamide (DMF)-induced hepatotoxicity were investigated with respect to the induction of cytochrome P-450 (CYP) and the activities of related enzymes. The rats were treated intraperitoneally with the organic solvents in olive oil (Single treatment groups: 450 [D1], 900 [D2], 1,800 [D3] mg DMF, and 346 mg toluene [T] per kg of body weight; Combined treatment groups: D1+T, D2+T, and D3+T) once a day for three days, while the control group received just the olive oil. Each group consisted of 4 rats. The activities of the xenobiotic metabolic enzymes and the hepatic morphology were assessed. The immunoblots indicated that the expression of CYP2E1 was considerably enhanced depending on the dosage of DMF and the CYP2E1 blot densities were significantly increased after treatment with both DMF and toluene, compared to treatment with DMF alone. The activities of glutathione-S-transferase and glutathione peroxidase were either decreased or remained unaltered after treatment with DMF and toluene, whereas the lipid peroxide levels were increased with increasing dosage of DMF and toluene. The liver tissue in the D3 group (1,800 mg/kg of DMF) showed signs of microvacuolation in the central vein region and a large necrotic zone around the central vein, in rats treated with both DMF (1,800 mg/kg) and toluene (D3T). These results suggest that the expression of CYP2E1 is induced by DMF and enhanced by toluene. These changes may have facilitated the accelerated formation of N-methylformamide (NMF) from toluene, and the generated NMF may directly induce liver damage.

• Korean Journal of Mathematics
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• 제19권3호
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• pp.279-289
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• 2011

Let E be a uniformly convex Banach space with a uniformly Gateaux differentiable norm, C be a nonempty closed convex subset of E and f : $C{\rightarrow}C$ be a fixed bounded continuous strong pseudocontraction with the coefficient ${\alpha}{\in}(0,1)$. Let $\{{\lambda}_t\}_{0<t<1}$ be a net of positive real numbers such that ${\lim}_{t{\rightarrow}0}{\lambda}_t={\infty}$ and S = {$T(s)$ : $0{\leq}s$ < ${\infty}$} be a nonexpansive semigroup on C such that $F(S){\neq}{\emptyset}$, where F(S) denotes the set of fixed points of the semigroup. Then sequence {$x_t$} defined by $x_t=tf(x_t)+(1-t)\frac{1}{{\lambda}_t}{\int_{0}}^{{\lambda}_t}T(s)x{_t}ds$ converges strongly as $t{\rightarrow}0$ to $\bar{x}{\in}F(S)$, which solves the following variational inequality ${\langle}(f-I)\bar{x},\;p-\bar{x}{\rangle}{\leq}0$ for all $p{\in}F(S)$.

• 대한수학회보
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• 제49권4호
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• pp.799-813
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• 2012

In this paper, we first show that the iteration {$x_n$} defined by $x_{n+1}=P((1-{\alpha}_n)x_n +{\alpha}_nTP[{\beta}_nTx_n+(1-{\beta}_n)x_n])$ converges strongly to some fixed point of T when E is a real uniformly convex Banach space and T is a quasi-nonexpansive non-self mapping satisfying Condition A, which generalizes the result due to Shahzad [11]. Next, we show the strong convergence of the Mann iteration process with errors when E is a real uniformly convex Banach space and T is a quasi-nonexpansive self-mapping satisfying Condition A, which generalizes the result due to Senter-Dotson [10]. Finally, we show that the iteration {$x_n$} defined by $x_{n+1}={\alpha}_nSx_n+{\beta}_nT[{\alpha}^{\prime}_nSx_n+{\beta}^{\prime}_nTx_n+{\gamma}^{\prime}_n{\upsilon}_n]+{\gamma}_nu_n$ converges strongly to a common fixed point of T and S when E is a real uniformly convex Banach space and T, S are two quasi-nonexpansive self-mappings satisfying Condition D, which generalizes the result due to Ghosh-Debnath [3].

• 대한수학회논문집
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• 제33권4호
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• pp.1141-1158
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• 2018

Hahn difference operator $D_{q,{\omega}}$ which is defined by $$D_{q,{\omega}}g(t)=\{{\frac{g(gt+{\omega})-g(t)}{t(g-1)+{\omega}}},{\hfill{20}}\text{if }t{\neq}{\theta}:={\frac{\omega}{1-q}},\\g^{\prime}({\theta}),{\hfill{83}}\text{if }t={\theta}$$ received a lot of interest from many researchers due to its applications in constructing families of orthogonal polynomials and in some approximation problems. In this paper, we investigate sufficient conditions for stability of the abstract linear Hahn difference equations of the form $$D_{q,{\omega}}x(t)=A(t)x(t)+f(t),\;t{\in}I$$, and $$D^2{q,{\omega}}x(t)+A(t)D_{q,{\omega}}x(t)+R(t)x(t)=f(t),\;t{\in}I$$, where $A,R:I{\rightarrow}{\mathbb{X}}$, and $f:I{\rightarrow}{\mathbb{X}}$. Here ${\mathbb{X}}$ is a Banach algebra with a unit element e and I is an interval of ${\mathbb{R}}$ containing ${\theta}$.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제6권2호
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• pp.1-8
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• 2002

Let $T_{\phi}$ be a generalized Gauss transformation and $[a_1,\;a_2,\;{\cdots}]_{T_{\phi}}$ be a symbolic representation of $x{\in}[0,\;1)$ induced by $T_{\phi}$, i.e., generalized continued fraction expansion induced by $T_{\phi}$. It is shown that the distribution of relative frequency of [$k_1,\;{\cdots},\;k_n$] in $[a_1,\;a_2,\;{\cdots}]_{T_p}$ satisfies Central Limit Theorem where $k_i{\in}{\mathbb{N}}$ for $1{\leq}i{\leq}n$.

• Journal of Species Research
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• 제3권1호
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• pp.27-34
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• 2014

Two species of Tortanus (Eutortanus) are newly recorded from shallow Korean waters: T. (E.) vermiculus Shen, 1955 and T. (E.) komachi Itoh, Ohtsuka and Sato, 2001. As a result of this study, five species are reported in the subgenus of the family Tortanidae in Korea. The sequence of cytochrome c oxidase subunit 1 (CO1) is also provided as a molecular characteristic.

• 대한의생명과학회지
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• 제17권3호
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• pp.173-176
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• 2011

Free-living Acanthamoeba are eukaryotic protozoan organisms that are widely distributed in the air, water, etc such as environment. Acanthamoeba ingest the Escherichia coli which will replicate in cytoplasm of Acanthamoeba. Bacterial pathogenicity or virulence is one of important determinant factors to survive in free-living Acanthamoeba and otherwise Acanthamoebic pathogenicity is also an important factor for their interactions. Bacterial association with pathogenic strain of Acanthamoeba T1 and T4 was lower about two times than non-pathogenic T7. Bacterial invasion percentages into T1 were higher about three times than T7 but bacterial survival in T7 was increased as T1. The capsule-deletion mutant exhibited limited ability for invasion/uptake by and survival inside pathogenic Acanthamoeba T4. E. coli-outer membrane protein A (OmpA) decreased bacterial association with A. castellanii by about three times and it had higher effects than lipopolysaccharides (LPS). Under favorable conditions, the mutants were not survived in Acanthamoeba up to 24 h incubation. Therefore, this review will report pathogenic and non-pathogenic Acanthamoeba strains interactions with E. coli and its several mutants, i.e., capsule, OmpA and LPS.

• 대한수학회지
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• 제48권1호
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• pp.159-167
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• 2011

We consider a curve $\alpha$= $\alpha$(s) in Minkowski 3-space $E_1^3$ and denote by {T, N, B} the Frenet frame of $\alpha$. We say that $\alpha$ is a slant helix if there exists a fixed direction U of $E_1^3$ such that the function is constant. In this work we give characterizations of slant helices in terms of the curvature and torsion of $\alpha$. Finally, we discuss the tangent and binormal indicatrices of slant curves, proving that they are helices in $E_1^3$.

• 한국의류학회지
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• 제29권12호
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• pp.1535-1545
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• 2005

신축성 소재 여성용 바디수트 원형 설계에 관한 선행연구에서 개발된 바디수트의 진동둘레길이 항목을 적용한 소매원형 제도방법이 제안되었다 본 연구는 선행연구와 연속적 맥락에서, 첫째, 신축성 소재의 물성을 고려한 패턴축소율의 적용을 제시하고 둘째, 그에 따라 개발된 여성용 바디수트 소매원형의 제도방법의 단계별 서술을 통해 교육 및 산업분야에서의 사용을 목적으로 하였다. 본 연구를 위하여 광범위하게 사용되고 있는 기존의 소매원형 제도방법을 우선, 선정하여(i.e. Joseph-Armstrong: T1, Shoben & Ward: T2, Esmod: T3 그리고 Joseph-Armstrong 절충식 : T4) 분석하였다. 그 가운데 소매의 앞 뒤차가 반영되지 않는(i.e. T1) 것과 반영되는(i.e. T2, T3 그리고 T4) 방법으로 나누어 구분하고 그에 따른 바디수트 소매샘플을 선행연구와 동일한 신축성 소재$(wale: 50\%/course: 70\%)$를 사용하여 제작한 후, 5인의 전문평가단을 구성하여 그 외관과 동작적합성을 평가하였다. 외관평가에서 관찰된 항목은 앞, 옆, 뒤 바디수트 소매의 여유분, 중심선의 위치와 소매길이, 그리고 바디수트 몸판과의 조화정도의 총 13항목이었고, 쾌적성 평가에서는 전방수직, 측방수직, 측방수평 3동작을 통해 실험의의 동작적합성을 평가하였으며 최종적으로 외관과 동작성이 적절히 조화된 바디수트 소매원형을 제안하는 과정을 거쳤다. 외관평가에서 T3>T4>T2>T1 순서로 우수하게 평가되었으며, 동작적합성 평가에서는 T1>T4>T2>T3의 순으로 평가되어, 외관적으로는 여유분이 적어 당겨 보이는 이유로 점수가 낮아도 쾌적성에서는 오히려 죄어주는 것이 안정감이 있다고 분석되었다. 따라서 외관과 쾌적감의 균형을 고려하였을 때 최종적으로 T4,즉, 소재의 신축성에 따른 패턴축소율(전체소매길이 : 1.0RR, 소매산높이 : 0.7RR, 팔꿈치둘레: 0.9RR)이 반영되고, 진동둘레에 제로 이즈량을 부가하였으며, 앞뒤차가 반영된 바디수트 소매 원형 제도방법 이 제안되었다.