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A mathematical model to predict fatigue notch factor of butt joints

  • Nguyen, Ninh T.;Wahab, M.A.
    • Structural Engineering and Mechanics
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    • v.6 no.4
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    • pp.467-471
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    • 1998
  • A mathematical model is developed to predict the fatigue notch factor of butt welds subject to number of parameters such as weld geometry, residual stresses under dynamic combined loading conditions (tensile and bending). Linear elastic fracture mechanics, finite element analysis, dimensional analysis and superposition approaches are used for the modelling. The predicted results are in good agreement with the available experimental data. As a result, scatters of the fatigue data can be significantly reduced by plotting S-N curve as ($S{\cdot}K_f$) vs. N.

The Relation between Effects of Positive Emotional Response of Female Customers in Busan and Behavioral Intention according to Their Food Service Consumption Propensity (부산지역 여성고객들의 외식소비성향이 긍정적 감정반응과 행동의도에 미치는 영향)

  • Han, Gyusang;Lee, Jong-Ho
    • Culinary science and hospitality research
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    • v.20 no.6
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    • pp.1-12
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    • 2014
  • This study was conducted by empirically analyzing the relation between effects of positive emotional response of female customers, who have at some point consumed food at Korean restaurants in Busan, and behavioral intention according to their food service consumption propensity. In order to achieve the objective of the study, the questionnaire survey was performed from March $10^{th}$ to $25^{th}$, and frequency analysis, confirmatory factor analysis, reliability analysis, correlation analysis, and SEM (structure equation model) were conducted by using SPSS 18.0 and AMOS for 248 questionnaires. As a result of an exploratory factor analysis, five factors were confirmed. In a confirmatory factor analysis, the average variance extracted (AVE) and composite reliability (CR) were confirmed as .508 to .665 and .905 to .946 respectively, which proved the convergent validity. In a hypothesis test, Hypothesis 1 was determined that the food service consumption propensity positively effects on emotional response. The results were as follows: the taste driven (${\beta}$=.325, t=3.907, p<.001), the health driven (${\beta}$=.190, t=2.688, p<.001), and the atmosphere driven (${\beta}$=.188, t=2.515, p<.001). Therefore, Hypothesis 1 was selected. Hypothesis 1 has determined that positive emotional response beneficially affects behavioral intention. As a result of an analysis, the standardized path coefficient was (${\beta}$=.496, t=6.388, p<.001), so Hypothesis 1 was selected. This result suggests that the taste driven factor has the biggest influence on emotional response in the food service consumption propensity for female customers, and food service business operators should strive to make a good restaurant atmosphere for customers to get positive emotional response (pleasure, comfort, satisfaction, and joy).

Effects of Ethanol Extract of Sargassum horneri on Adipocyte Differentiation and Adipogenesis in 3T3-L1 Preadipocytes (괭생이모자반 에탄올 추출물이 3T3-L1 지방전구세포의 분화 및 adipogenesis에 미치는 영향)

  • Kwon, Da Hye;Choi, Yung Hyun;Kim, Byung Woo;Hwang, Hye Jin
    • Journal of Life Science
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    • v.29 no.2
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    • pp.209-214
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    • 2019
  • Sargassum horneri (Turner) C. Agardh is a marine brown algae widely distributed in the North Pacific Ocean. It is known for its anti-inflammatory and anti-atopic effects. In this study, we determined the effects of ethanol extract of Sargassum horneri (Turner) C. Agardh (EESH) on anti-obesity activities in 3T3-L1 preadipocytes. Our results indicated that treatment with EESH decreased the differentiation of 3T3-L1 preadipocytes in a dose-dependent manner, as confirmed by a decrease in lipid droplet content observed by oil red O staining. The concentrations of cellular triglycerides were also reduced in 3T3-L1 cells after treatment with EESH. Triglyceride content was inhibited by 13%, 16%, and 23% after treatment with 250, 500, and $1,000{\mu}g/ml$ of EESH in 3T3-L1 cells, respectively. Western blotting analysis showed that EESH suppressed adipogenic transcription factor expression in a dose dependent manner. Specifically, it suppressed cytidine-cytidine-adinosine-adenosine-thymidine (CCAAT) /enhancer binding proteins $(C/EBP){\alpha}$, $C/EBP{\beta}$ and peroxisome proliferator-activated receptor $(PPAR){\gamma}$. This indicated that EESH could control the expression of adipogenic transcription factors and inhibit the differentiation of adipocytes. Taken together, these findings demonstrated that EESH showed anti-obesity effects and could have potential uses in the field of nutraceuticals.

The Systematization of the Concept on Apparel Store Service and Relationship with the Shopping Type of Consumer (의류점포의 서비스 개념 체계와 쇼핑유형과의 관련성)

  • 김윤희;김미영
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.1
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    • pp.183-194
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    • 2001
  • The purpose of this study are to systematize the concept on apparel store service and to provide the importance of each service according to the shopping types as well as demographic characteristics of consumers. The data was collected from 628 females and analyzed by factor analysis, reliability analysis, mean, percentage, cluster analysis, ANOVA, Duncan test, paired t-test, and t-test. The results are as follows: 1) All apparel stores consist of two categories, Products and Services. The products obviously entail whatever the store is selling. The services, on the other hand, can be broken down into three different factors of responsibility: public relations service, store environmental service, and promotional service. 2) Consumers can be classified into one of four categories: conventional type, practical type, recreational type, and casual type. 3) A recreational type and a practical type shoppers take into consideration all three service factors. The conventional and casual type shoppers, as compared to the recreational or practical type shoppers, arent really concerned with much of anything, least of the promotional service factor. 4) It has been found that the typical Korean consumer is more concerned with the public relations service factor, rather than the store environmental service factor or promotional service factor. 5) It has been found that the importance of services are significantly different in relation to the demographic characteristics, whether that be age, marital status, or the age of the youngest child.

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Attitudes of Hospice Volunteers towards Death with Dignity (호스피스 자원봉사자의 존엄사에 대한 태도요인)

  • Hwang, Byung-Deog
    • The Korean Journal of Health Service Management
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    • v.5 no.2
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    • pp.1-14
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    • 2011
  • The purpose of this study was analyzed the factors of influencing toward attitude to death with dignity to hospice volunteers. The data was collected for 21 days from 14 March to 3 April 2010. Among a total of 220 cases of the questionaries, only 195 cases were used. To data were analyzed by factor analysis, independent t-test, one-way anova and logistic regression using PASW statistics 18.0. The results were as follows; The attitudes towards death with dignity according to general characteristics was high in those with will to agreed to the passive euthanasia than those opposite to the attitude factors, namely, acceptive, the right to decide, negative, and dereliction of duty attitude factors. Significant variables for effects of death with dignity were gender, acceptive attitude factor and dereliction of duty attitude factors. Given that main provider of human organs is the brain-dead and we don't have enough organ donation, death with dignity should be linked with activating policy of organ donation, while solving donation shortage problem. This way, constructing social implementation and sharing consciousness on organ donation, would be diluting the bio-ethic controversies.

Low T3 syndrome in Kawasaki disease: Relation to serum levels of tumor necrosis factor-α, interleukin-6 and NT-proBNP (가와사끼병에서의 저 T3 증후군 : 혈청 tumor necrosis factor-α, interleukin-6 및 NT-proBNP 농도와의 관계)

  • Cho, Hye Kyung;Sohn, Jin A;Kim, Hae Soon;Sohn, Sejung
    • Clinical and Experimental Pediatrics
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    • v.52 no.2
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    • pp.234-241
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    • 2009
  • Purpose : We investigated the relationship between thyroid hormone and serum tumor necrosis factor (TNF-${\alpha}$), interleukin (IL-6) and N-terminal fragment of pro-brain natriuretic peptide (NT-proBNP) in patients with Kawasaki disease (KD). Methods : Serum levels of thyroid hormone, TNF-${\alpha}$, IL-6, and NT-proBNP were measured in 52 KD patients in the acute and subacute phase and 10 patients with acute febrile illness (control group). TNF-${\alpha}$ and IL-6 were determined by sandwich enzyme-linked immunosorbent assay (ELISA). Echocardiography was performed to detect coronary artery lesions (CAL) in KD patients. Results : Low $T_3$ syndrome occurred in 63.5% of KD patients. $T_3$ in the acute phase of KD was lower than that in the control. In KD patients, $T_3$ was lowered in the acute phase and elevated in the subacute phase, whereas TNF-${\alpha}$, IL-6 and NT-proBNP were elevated in the acute phase and decreased in the subacute phase. NT-proBNP, and IL-6 were higher in patients with low $T_3$ than in those with normal $T_3$. In addition, $T_3$ inversely correlated with IL-6 and NT-proBNP. Of the 4 patients with CAL, 3 had very low $T_3$. Compared with intravenous immunoglobulin (IVIG)-responsive patients, IVIG-resistant patients had lower $T_3$ and higher IL-6 and NT-proBNP. Conclusion : $T_3$ decreases in the acute phase of KD and normalizes in the subacute phase without thyroid hormone replacement. Low $T_3$ may be partially induced by IL-6 rather than TNF-${\alpha}$, and is strongly associated with high NT-proBNP. $T_3$ in KD may be used for the differential diagnosis, monitoring the activity of the disease, and predicting the severity of inflammation.

The WNT/Ca2+ pathway promotes atrial natriuretic peptide secretion by activating protein kinase C/transforming growth factor-β activated kinase 1/activating transcription factor 2 signaling in isolated beating rat atria

  • Li, Zhi-yu;Liu, Ying;Han, Zhuo-na;Li, Xiang;Wang, Yue-ying;Cui, Xun;Zhang, Ying
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.6
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    • pp.469-478
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    • 2022
  • WNT signaling plays an important role in cardiac development, but abnormal activity is often associated with cardiac hypertrophy, myocardial infarction, remodeling, and heart failure. The effect of WNT signaling on regulation of atrial natriuretic peptide (ANP) secretion is unclear. Therefore, the purpose of this study was to investigate the effect of Wnt agonist 1 (Wnta1) on ANP secretion and mechanical dynamics in beating rat atria. Wnta1 treatment significantly increased atrial ANP secretion and pulse pressure; these effects were blocked by U73122, an antagonist of phospholipase C. U73122 also abolished the effects of Wnta1-mediated upregulation of protein kinase C (PKC) β and γ expression, and the PKC antagonist Go 6983 eliminated Wnta1-induced secretion of ANP. In addition, Wnta1 upregulated levels of phospho-transforming growth factor-β activated kinase 1 (p-TAK1), TAK1 banding 1 (TAB1) and phospho-activating transcription factor 2 (p-ATF2); these effects were blocked by both U73122 and Go 6983. Wnta1-induced ATF2 was abrogated by inhibition of TAK1. Furthermore, Wnta1 upregulated the expression of T cell factor (TCF) 3, TCF4, and lymphoid enhancer factor 1 (LEF1), and these effects were blocked by U73122 and Go 6983. Tak1 inhibition abolished the Wnta1-induced expression of TCF3, TCF4, and LEF1 and Wnta1-mediated ANP secretion and changes in mechanical dynamics. These results suggest that Wnta1 increased the secretion of ANP and mechanical dynamics in beating rat atria by activation of PKC-TAK1-ATF2-TCF3/LEF1 and TCF4/LEF1 signaling mainly via the WNT/Ca2+ pathway. It is also suggested that WNT-ANP signaling is implicated in cardiac physiology and pathophysiology.

RELATIVE SEQUENCE ENTROPY PAIRS FOR A MEASURE AND RELATIVE TOPOLOGICAL KRONECKER FACTOR

  • AHN YOUNG-HO;LEE JUNGSEOB;PARK KYEWON KOH
    • Journal of the Korean Mathematical Society
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    • v.42 no.4
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    • pp.857-869
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    • 2005
  • Let $(X,\;B,\;{\mu},\;T)$ be a dynamical system and (Y, A, v, S) be a factor. We investigate the relative sequence entropy of a partition of X via the maximal compact extension of (Y, A, v, S). We define relative sequence entropy pairs and using them, we find the relative topological ${\mu}-Kronecker$ factor over (Y, v) which is the maximal topological factor having relative discrete spectrum over (Y, v). We also describe the topological Kronecker factor which is the maximal factor having discrete spectrum for any invariant measure.

A Study on Health Promoting Behavior In Post-Mastectomy Patients (유방절제술을 받은 여성의 건강증진행위에 관한 연구)

  • Kim, Hyun Ju;So, Hyang Sook
    • Korean Journal of Adult Nursing
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    • v.13 no.1
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    • pp.82-95
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    • 2001
  • The purpose of this study was to examine the relationship among perceived health status, self-esteem, self-efficacy and health promoting behavior, and to determine the predictors of health promoting behavior in post-mastectomy patients. The study, a descriptive correlational study, was done with structural questionnaires. A total of 51 post-mastectomy subjects from C university hospital in Kwang-ju, South Korea completed mail-in self-reporting questionnaires during a three month period from March to June, 1999. The data were collected using Lawstone's(1982) perceived health status scale, Rosenberg's(1965) self-esteem scale, the modified self-efficacy scale(Shere et al, 1982), and the modified health promoting lifestyle profile (Walker et al, 1987). The data obtained were analyzed according to percentage, mean and standard deviation, principal component analysis, varimax rotation, t-test, ANOVA, Pearson's correlation, and stepwise multiple regression. The results were as follows: 1. The health promoting behavior measurement resulted in six factors. Each factor was labelled as follows: self-actualization, nutrition, stress management, exercise, health responsibility and interpersonal support. The total percent of variance explained by the six factors was 58.4%. 2. The mean score of health promoting behavior was 85.92(range 58~117). The scores of six factor were nutrition 3.20, self-actualization 2.59, stress management 2.58, interpersonal support 2.58, health responsibility 2.49, and exercise 2.34 on a four point scale. 3. When the score of health promoting behavior factors were compared by general characteristics. Factor I: self-actualization, differed significantly by the frequency of pregnancy (F=3.06, p=.037). Factor II: nutrition differed significantly by drinking experience(t=-2.26, p=.028) and the pre- or post stage of menopause(F=2.69, p=078). FactorIII: stress management differed significantly depending on regularity of mensturation(t=-2.12, p= .042). FactorIV: exercise differed significantly by type of religion (F=2.49, p=.072), marital status(F=5.03, p=.010), and feeding type (F=2.64, p=.036). Factor V: health responsibility differed significantly by regularity of mensturation(t=2.18, p=.037). 4. The total health promoting behavior score was significantly related to self-esteem and perceived health status(r=.610, p.006; r= .378, p=.006). The score of selfactualization also corresponded with selfesteem and perceived health status(r=.556, p=.001; r=.343, p=.013). 5. The predictor to explain the score of health promoting behavior was self-esteem, which accounted for 37.1% of the total variance. The predictor to explain the score of self-actualization was self-esteem, which accounted for 30.9% of the total variance. The score of nutrition was primarily affected by both premenopause and drinking experience, which accounted for 13.1% and 9.5% respectively. Finally, the score of exercise was dictated by marriage, Buddhism, no experience of breast feeding, which accounted for 17%, 9.8%, & 5.2% respectively. In conclusion, self-esteem is the main predictor for health promoting behavior in post-mastectomy women. These findings suggest a need for nursing strategies which promote self-esteem in such patients.

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The Relationship between Anxiety, Anger and Fatigue among Stress factor of Nursing Students in Clinical Practice (간호학생들의 임상실습시 스트레스에 따른 불안, 분노 및 피로경험)

  • Han, San-Young;Lee, Young-Mee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.2
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    • pp.554-561
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    • 2012
  • The purpose of this study was to identify the relationship between anxiety, anger and fatigue among stress factor in clinical practice of nursing students. The subjects were 197 nursing students who have practiced at the hospital in T city. Data was analyzed by using descriptive statistics, ANOVA, t-test and pearson's correlation coefficient. The mean score for stress was 3.82. The mean score for anxiety was 48.82. The mean score for anger was 1.17. The mean score for fatigue was 30.96. The factor of stress was a significant difference of anxiety according to conference, theory and practice, satisfaction of clinical practice. The factor of stress was a significant difference of anger according to report, theory and practice, orientation, nurse, environment. The factor of stress was a significant difference of fatigue according to conference, orientation, environment, patient relationship. In results, This study revealed that there was a significant correlation among stress, anxiety, anger and fatigue of nursing students in clinical practice.