• Title/Summary/Keyword: Systemic effects

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The Effects of Circuit Training and Circuit Training with Whole Body Vibration on Pulmonary Function in Adolescent

  • Jun, Hyun ju;Jeong, Chan Joo;Yang, Hoe Song;Jeong, Ye rim;Jegal, Hyuk;Yoo, Young Dae
    • Journal of International Academy of Physical Therapy Research
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    • v.6 no.2
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    • pp.902-907
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    • 2015
  • The purpose of this study was to parallel circuit training and circuit training with sonic systemic mechanism was to compare the differences in pulmonary function and chest expansion in adult men. This study was performed on 20 subjects. 20 subjects were divided into two groups; Circuit training group(n=10), Circuit training with sonic systemic mechanism(n=10). Both of the group performed the exercise 3 times a week for 5 weeks. The data was analyzed by the Repeated t-test for comparing before, during and after changes of factors in each group and the Independent t-test for comparing the between groups. The result are as follows. Circuit training group was statistically significant difference FVC, FEV1/FVC(p<.05), Circuit training with sonic systemic mechanism group was statistically significant difference PEF, VC in pulmonary function(p<.05). Circuit training group was statistically significant difference FEV1/FVC of between the two group in pulmonary function(p<.05). Circuit training group and circuit training with sonic systemic mechanism group was statistically significant difference in chest expansion(p<0.05) and there was no statistically significant difference of between the two group in chest expansion(p>.05).

Mediating Effects of Resilience on the Relationship between Stress and Therapeutic Compliance in Patients with Systemic Lupus Erythematosus (루푸스 환자의 스트레스와 치료지시이행의 관계에 미치는 극복력의 매개효과)

  • Lee, Mi Hye;Min, Hye Sook
    • Journal of muscle and joint health
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    • v.24 no.3
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    • pp.196-204
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    • 2017
  • Purpose: This study was conducted to explore the mediating effect of resilience in the relationship between stress and therapeutic compliance in patients with systemic lupus erythematosus. Methods: The subject (N=145) was a systemic lupus erythematosus patient who visited the D Hospital in B city. Data collection was conducted from January 2016 to August 2016. Twenty-five resilience measurement tools, 20 stress measurement tools, 39 therapeutic compliance measurement tools used to measure resilience, stress and therapeutic compliance levels. The collected data were analyzed using descriptive analysis, Pearson correlation, 3-step regression analysis of Baron and Kenny, and Sobel test in SPSS/WIN 21.0. Results: There was a significant negative correlation between stress and therapeutic compliance, a significant negative correlation between stress and resilience, and significant positive correlation between resilience and therapeutic compliance. Resilience showed a direct effect on therapeutic compliance through stress as a mediating variable. Conclusion: It is necessary to develop appropriate resilience enhancement program to improve therapeutic compliance with systemic lupus erythematosus.

Inhalation Exposure to Nickel Hydroxide Nanoparticles Induces Systemic Acute Phase Response in Mice

  • Kang, Gi-Soo;Gillespie, Patricia Anne;Chen, Lung-Chi
    • Toxicological Research
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    • v.27 no.1
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    • pp.19-23
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    • 2011
  • It has been proposed that acute phase response can be a mechanism by which inhaled particles exert adverse effects on the cardiovascular system. Although some of the human acute phase proteins have been widely studied as biomarkers of systemic inflammation or cardiovascular diseases, there are only a few studies that investigated the role of serum amyloid P (SAP), a major acute phase protein in mice. In this study, we investigated the changes in SAP, following inhalation exposure to nickel hydroxide nanoparticles (nano-NH). We conducted 1) acute (4 h) exposure to nano-NH at 100, 500, and $1000\;{\mu}g/m^3$ and 2) sub-acute (4h/d for 3d) exposure at $1000\;{\mu}g/m^3$, then measured serum SAP protein levels along with hepatic Sap mRNA levels. The results show that inhaled nano-NH can induce systemic acute phase response indicated by increased serum SAP levels and hepatic Sap mRNA levels. To the best of our knowledge, this is the first study showing induction of SAP in response to repeated particle exposure, and the results suggest that SAP can be used as a biomarker for systemic inflammation induced by inhaled particles.

A Systemic Analysis of S-1 Regimens for Treatment of Patients with Colon Cancer

  • Zhang, En;Cao, Wei;Cheng, Chong;Huo, Bin-Liang;Wang, Yong-Heng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.5
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    • pp.2191-2194
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    • 2014
  • Background: Fluorouracil-based regimens have been widely accepted and recommended in the guidelines for treating patients with early or advanced staged colon cancer, although results are controversial. Here we performed a systemic analysis to evaluate the impact of S-1 based regimens on response and survival of patients with colon cancer. Methods: Clinical studies evaluating the impact of S-1 based regimens on response and survival of patients with colon cancer were identified using a predefined search strategy. Summary response rates (RRs) to treatment were calculated. Results: Six clinical studies which including 227 patients with advanced colorectal cancer were considered eligible for inclusion. Two studies were conducted using combination of S-1 and Oxaliplatin, and four studies featured S-1 and irinotecan. Systemic analysis showed that, in all patients, pooled RRs was 43.17%. Major adverse effects were hematological toxicities, gastrointestinal disturbance, neurosensory toxicity. No treatment related death occurred. Conclusion: This systemic analysis suggests that S-1 based regimens, both with oxaliplatin or irinotean are associated with acceptable response and toxicity in patients with colon cancer.

The Effect of Uncertainty and Fatigue Perceived by Patients with Systemic Lupus Erythematosus on Resilience (루푸스 환자가 지각하는 불확실성과 피로가 극복력에 미치는 영향)

  • Cho, OK-Hee;Lim, Jong-Mi
    • Journal of Digital Convergence
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    • v.19 no.11
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    • pp.615-623
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    • 2021
  • The purpose of this study was to identify the factors influencing resilience of patients with systemic lupus erythematosus. The subject(N=118) was a systemic lupus erythematosus patient who visited the E hospital in D city. The collected data were analyzed by descriptive statistics, t-tset, ANOVA, pearson correlation, and multiple regression. As a result of the study, impact domain of uncertainty, fatigue, self-management domain of uncertainty, trust in doctors domain of uncertainty significant effects on resilience. Based on this study, in order to improve the resilience of patients with systemic lupus erythematosus, a multifaceted approach is needed to reduce the uncertainty perceived by the patient and control fatigue. In addition, it is required to develop an effective nursing intervention program to enhance resilience reflecting influencing factors.

Chemical Control Effect Against Spot Clothing Wax Cicada, Lycorma delicatula (Hemiptera: Fulgoridae) Nymphs and Adults (꽃매미(Lycorma delicatula) 약충과 성충에 대한 약제방제 효과)

  • Kim, Sun-Kook;Lee, Gi-Yeul;Shin, Yon-Ho;Kim, Gil-Bah
    • The Korean Journal of Pesticide Science
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    • v.14 no.4
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    • pp.440-445
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    • 2010
  • This study was carried out to investigate the toxicities of five registered insecticides to the Lycorma delicatula nymphs and adults. Insecticidal activities were evaluated by testing systemic and residual effects in the laboratory, and control efficacy in the vineyard. For the 3rd nymphal instars and adults, etofenprox+diazinon, chlorpyrifos, etofenprox, dinotefuran and imidacloprid showed perfect insecticidal activity. The systemic effects of dinotefuran and etofenprox+diazinon on grape roots at half concentration were showed the adult mortality of 82.2% and 84.4%, respectively. Chlorpyrifos at recommended concentration was showed mortality of 86.0%. The leaf systemic effects at recommended and half concentrations of all insecticides except dinotefuran were lower than 65% but the mortality at double concentration of chlorpyrifos, dinotefuran, etofenprox were more than 82%. The residual effect between etofenprox+diazinon and dinotefuran at recommended and double concentrations were 100% at 14 days after treatment, the other insecticides have low efficacy. All the four insecticides showed 87% control value on nymphs in the field test and adults appeared more than 96% control value st and adinotefuran, etofenprox+diazinon, however, the other insecticides decreased to 59.1 % and 61.2%. Therefore, dinotefuran and etofenprox+diazinon showing high systemic effects to roots and long residual effects to leafs have high control efficacies.

Effects of Temperature on Systemic Infection and Symptom Expression of Turnip mosaic virus in Chinese cabbage (Brassica campestris)

  • Chung, Bong Nam;Choi, Kyung San;Ahn, Jeong Joon;Joa, Jae Ho;Do, Ki Seck;Park, Kyo-Sun
    • The Plant Pathology Journal
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    • v.31 no.4
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    • pp.363-370
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    • 2015
  • Using the Chinese cabbage (Brassica campestris) cultivar 'Chun-goang' as a host and turnip mosaic virus (TuMV) as a pathogen, we studied the effects of ambient temperature ($13^{\circ}C$, $18^{\circ}C$, $23^{\circ}C$, $28^{\circ}C$ and $33^{\circ}C$) on disease intensity and the speed of systemic infection. The optimal temperature for symptom expression of TuMV was $18-28^{\circ}C$. However, symptoms of viral infection were initiated at $23-28^{\circ}C$ and 6 days post infection (dpi). Plants maintained at $33^{\circ}C$ were systemically infected as early as 6 dpi and remained symptomless until 12 or 22 dpi, depending on growth stage at the time of inoculation. It took 45 days for infection of plants grown at $13^{\circ}C$. Quantitative realtime polymerase chain reaction (q-PCR) results showed that the accumulation of virus coat protein was greater in plants grown at $23-28^{\circ}C$. The speed of systemic infection increased linearly with rising ambient temperature, up to $23^{\circ}C$. The zero-infection temperature was $10.1^{\circ}C$. To study the effects of abruptly elevated temperatures on systemic infection, plants inoculated with TuMV were maintained at $10^{\circ}C$ for 20 d; transferred to a growth chamber at temperatures of $13^{\circ}C$, $18^{\circ}C$, $23^{\circ}C$, $28^{\circ}C$, or $33^{\circ}C$ for 1, 2, or 3 d; and then moved back to $10^{\circ}C$. The numbers of plants infected increased as duration of exposure to higher temperatures and dpi increased.

Diffusion of Knowledge Related to Systemic Disease among Dental Hygienists (치과위생사의 전신질환 관련 지식 확산)

  • Kim, Young-Jin;Lim, Soon-Ryun
    • Journal of dental hygiene science
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    • v.16 no.1
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    • pp.9-17
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    • 2016
  • This study was aimed to identify the diffusion of systemic disease-related knowledge among dental hygienists. Two hundreds and eleven dental hygienists were selected for the study. Data was collected between August 31, 2015 and September 20, 2015 by handing out questionnaires. Returned questionnaires were analyzed by descriptive statistics, t-test, and ANOVA. Dental hygienists showed overall mean of 0.64 on the systemic disease related knowledge. Age, education level, career, and educational experience showed significant influence on the systemic disease knowledge (p<0.01). Dental hygienists revealed overall mean of 0.61 (full mark=1) on the usefulness recognition of systemic disease related knowledge. Age (p<0.001), education level (p<0.01), career (p<0.001), and educational experience (p<0.01) showed significant effects on the usefulness recognition of systemic disease knowledge. Degree of how dental hygienists apply the systemic disease-related knowledge to the service was mean 0.86 (full mark=2). Age (p<0.01), education level (p<0.01), career (p<0.01), and educational experience (p<0.001) had significant impacts on how dental hygienists apply the systemic disease related knowledge to the service. The diffusion of systemic disease knowledge among dental hygienists was 2.17, which represented 'persuade'. These results indicated that a study is needed to understand the diffusion of systemic disease knowledge among dental hygienists and to identify obstacles in the process. Moreover, an education program should be developed to offer practical training on the systemic disease-related knowledge. Further studies should evaluate the effectiveness of the program.

Effect of 2-6 weeks of systemic steroids on bone mineral density in children

  • Kuniyil, Athira;Pal, Somdipa;Sachdev, Namrita;Yadav, Tribhuvan Pal
    • Clinical and Experimental Pediatrics
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    • v.65 no.5
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    • pp.254-261
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    • 2022
  • Background: The use of systemic steroids for 6+ weeks in children is associated with decreased bone mineral content (BMC) and density (BMD). However, the effects of a shorter duration of use on BMD are unknown. Purpose: To determine the effect of the use of systemic steroids for 2-6 weeks on BMD and BMC in pediatric patients. Methods: Twenty-five pediatric patients (21 with tuberculosis, 2 with systemic juvenile idiopathic arthritis, 1 with inflammatory bowel disease, 1 with autoimmune hemolytic anemia) who received systemic steroids for 2-6 weeks and 25 age- and sex-matched controls were enrolled. BMC, BMD, and z scores of the whole body (WB), lumbar spine (LS), nondominant distal radius (DR), and total body less the head (TBLH) were determined by dual-energy x-ray absorptiometry at baseline, the end of steroid therapy or 6 weeks (whichever was earlier; first follow-up), and at the end of 3 months from baseline (second follow-up) in patients and at baseline in controls. The values were adjusted for confounding variables. Continuous and categorical variables were compared using Student t test and the chi-square test or Fisher exact test, respectively. Pairwise comparisons employed Bonferroni correction. Results: Statistically significant decreases in BMC, BMD, and all z scores were observed. BMC declined by 5.37%, 2.08%, 1.82%, and 2.27%, and 11.42%, 3.75%, 3.34%, and 4.17% for WB, LS, DR, and TBLH, respectively, at the first and second follow-ups, respectively. Similarly, BMD declined by 2.01%, 2.31%, 2.18%, and 1.70% and 4.59%, 3.76%, 3.14%, and 3.50% for the WB, LS, DR, and TBLH, respectively, at the first and second follow-ups, respectively. A significant negative correlation was found among bone densitometric parameters, duration, and cumulative dose. Conclusion: The use of systemic steroids for 2-6 weeks in pediatric patients decreased the BMD and BMC of trabecular and cortical bones, an effect that persisted after discontinuation.

Systemic review of Xiaochaihutang and its correlation with KCD (소시호탕 systemic review 및 KCD 코드 대조)

  • Lee, Ji Ho;Park, Sun Dong;Kim, Young Woo
    • Herbal Formula Science
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    • v.28 no.1
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    • pp.117-135
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    • 2020
  • Objectives : Xiaochaihutang(小柴胡湯) is a famous herbal prescription in the Traditional Korean Medicine, and its components include Bupleuri Radix(柴胡), Scutellariae Radix(黃芩), Ginseng Radix(人蔘), Pinelliae Tuber(半夏), Glycyrrhizae Radix et Rhizoma(甘草), Zingiberis Rhizoma Crudus(生薑), Zizyphi Fructus(大棗). Methods : In this study, we reviewed the effects of xiaochaihutang by searching Pubmed. And we connected with Korean Standard Classification of Diseases (KCD) and the effects of xiaochaihutang. Results and Conclusion : The effects of xiaochaihutang was related with B18, C22, C34, C56, J30, J45, K70, K74, K76, F32, F33, F34, F41 as indicated by KCD. In clinics, the medical doctors almost use the KCD code for insurance. This review give us the scientific clue of Xiaochaihutang's effect in KCS system.