Acknowledgement
We acknowledge the statistical analysis done by Dr Ashish Yadav-Statistician.
References
- Seth A, Aggarwal A. Monitoring adverse reaction to steroid therapy in children. Indian Pediatr 2004;41:349-57.
- Shuhart CR, Yeap SS, Anderson PA, Jankowski LG, Lewiecki EM, Morse LR, et al. Executive summary of the 2019 ISCD Position Development Conference on monitoring treatment, dxa cross-calibration and least significant change, spinal cord injury, peri-prosthetic and orthopedic bone health, transgender medicine, and pediatrics. J Clin Densitom 2019;22:453-71. https://doi.org/10.1016/j.jocd.2019.07.001
- Gordon CM, Bachrach LK, Carpenter TO, Crabtree N, El-Hajj Fuleihan G, Kutilek S, et al. Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions. J Clin Densitom 2008;11:43-58. https://doi.org/10.1016/j.jocd.2007.12.005
- Nurmalia LD, Tambunan T, Amir I. Comparison of bone mineral density in steroid dependent, frequent relapse, and infrequent relapse nephrotic syndrome in children. Paediatr Indones 2010;50:193-8. https://doi.org/10.14238/pi50.4.2010.193-8
- Borey NF, Addosooki A, Mohammad MA, El-Sonbaty MM, EL-Toukhy SE. Metabolic bone disease in children with idiopathic nephrotic syndrome. Life Sci J 2012;9:275-80.
- Leonard MB, Feldman HI, Shults J, Zemel BS, Foster BJ, Stallings VA. Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. N Engl J Med 2004;351:868-75. https://doi.org/10.1056/NEJMoa040367
- Mishra OP, Meena SK, Singh SK, Prasad R, Mishra RN. Bone mineral density in children with steroid-sensitive nephrotic syndrome. Indian J Pediatr 2009;76:1237-9. https://doi.org/10.1007/s12098-009-0256-1
- Tsampalieros A, Gupta P, Denburg MR, Shults J, Zemel BS, Mostoufi-Moab S, et al. Glucocorticoid effects on changes in bone mineral density and cortical structure in childhood nephrotic syndrome. J Bone Miner Res 2013;28:480-8. https://doi.org/10.1002/jbmr.1785
- Lien G, Flato B, Haugen M, Vinje O, Sorskaar D, Dale K, et al. Frequency of osteopenia in adolescents with early-onset juvenile idiopathic arthritis: a long-term outcome study of one hundred five patients. Arthritis Rheum 2003;48:2214-23. https://doi.org/10.1002/art.11097
- Valta H, Lahdenne P, Jalanko H, Aalto K, Makitie O. Bone health and growth in glucocorticoid treated patients with juvenile idiopathic arthritis. J Rheumatol 2007;34:831-6.
- Okumus O, Erguven M, Deveci M, Yilmaz O, Okumus M. Growth and bone mineralisation in patients with Juvenile idiopathic arthritis. Indian J Pediatr 2008;75:239-43. https://doi.org/10.1007/s12098-008-0052-3
- Kashef S, Saki F, Karamizadeh Z, Kashef MA. Bone mineral density in children with systemic lupus erythematosus and juvenile rheumatoid arthritis. Ann Saudi Med 2007;27:427-31. https://doi.org/10.4103/0256-4947.51458
- Dey S, Jahan A, Yadav TP, Bhagwani DK, Sachdev N. Measurement of bone mineral density by dual energy X-ray absorptiometry in juvenile idiopathic arthritis. Indian J Pediatr 2014;81:126-32. https://doi.org/10.1007/s12098-013-1037-4
- Lilleby V, Lien G, Froslie K F, Haugen M, Flato B, Forre O. Frequency of osteopenia in children and young adults with childhood-onset lupus erythematosus. Arthritis Rheum 2005;52:2051-9. https://doi.org/10.1002/art.21115
- Trapani S, Civinini R, Ermini M, Paci E, Falcini F. Osteoporosis in juvenile systemic lupus erythematosus: a longitudinal study on the effect of steroids on bone mineral density. Rheumatol Int 1998;18:45-9. https://doi.org/10.1007/s002960050056
- Phan V, Blydt-Hansen T, Fever J, Also N, Arora S, Atkinson S, et al. Skeletal findings in the first 12 months following initiation of glucocorticoid therapy for pediatric nephrotic syndrome. Osteoporos Int 2014;25:627-37. https://doi.org/10.1007/s00198-013-2466-7
- Chaudhary S, Aggarwal I, Sheshadri MS. Calcium and vitamin D for osteoprotection in children with new onset nephrotic syndrome treated with steroids: a randomised controlled interventional study. Pediatr Nephrol 2014;29:1025-32. https://doi.org/10.1007/s00467-013-2720-4
- Kosan C, Ayar G, Orbak Z. Effects of steroid treatment on bone mineral metabolism in children with glucocorticoid sensitive nephrotic syndrome. West Indian Med J 2012;61:627-30.
- Panda K, Dey S, Sachdev N, Yadav TP. Effect of 6-12 weeks of systemic glucocorticoids on bone mineral density in children. J Clin Diagnostic Res 2021;15:SC01-6.
- Gupta P, Bhatia B. Corticosteroid physiology and principles of therapy. Indian J Pediatr 2008;75:1039-44. https://doi.org/10.1007/s12098-008-0208-1
- Sarinho ESC, Melo VMPP. Glucocorticoid-induced bone disease: mechanisms and importance in pediatric practice. Rev Paul Pediatr 2017;35:207-15. https://doi.org/10.1590/1984-0462;2017/;35;2;00007
- Moon RJ, Gilbert RD, Page A, Murphy L, Taylor P, Cooper C, et al. Children with nephrotic syndrome have greater bone area but similar volumetric bone mineral density to healthy controls. Bone 2014;58:108-3. https://doi.org/10.1016/j.bone.2013.10.012
- Rodd C, Lang B, Ramsay T, Alos N, Huber AM, Cabral DA, et al. Incident vertebral fractures among children with rheumatic disorders 12 months after glucocorticoid initiation: a national observational study. Arthritis Care Res (Hoboken) 2012;64:122-31. https://doi.org/10.1002/acr.20589
- Gulati S, Sharma RK, Gulati K, Singh U, Srivastava A. Longitudinal follow-up of bone mineral density in children with nephrotic syndrome and the role of calcium and vitamin D supplements. Nephrol Dial Transplant 2005;20:1598-603. https://doi.org/10.1093/ndt/gfh809
- Bak M, Serdaroglu E, Guclu R. Prophylactic calcium and vitamin D treatments in steroid-treated children with nephrotic syndrome. Pediatr Nephrol 2006;21:350-4. https://doi.org/10.1007/s00467-005-2118-z
- Falcini F, Trapani S, Civinini R, Capone A, Ermini M, Bartolozzi G. The primary role of steroids on the osteoporosis in juvenile rheumatoid patients evaluated by dual energy X-ray absorptiometry. J Endocrinol Invest 1996;19:165-9. https://doi.org/10.1007/BF03349860
- Tantawy AA, El Bostany EA, Matter RM, El Ghoroury EA, Ragab S, El Sherif NH. Bone mass and biochemical markers of bone turnover in children and adolescents with chronic immune thrombocytopenia: relation to corticosteroid therapy and vitamin D receptor gene polymorphisms. Platelets 2013;24:282-7. https://doi.org/10.3109/09537104.2012.690544