• 한국실내디자인학회논문집
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• 제21권1호
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• pp.78-85
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• 2012

The relevance between organisms and their external environment covers everything including humans, natural and artificial surroundings, regarding which academic and scientific understanding has continued. Relevant elements established by inter-dependence between humans and environment and the unity of life should be translated from the perspective of a whole, not of unit elements or reduction. That is, a space is formed by its own program and assumes sustainable relevance based on interactions between internal and external spaces, not building an independent system. The present study aims to present the feasibility of a potential mutant space formed by invisible arenas between individuals and evolutionary space formation based on an ecological paradigm Accordingly, this study suggested that evolutionary attributes as the major power source of biological changes could verify the virtual multiplicity of a new space formation, and that the potential form generation of hybrid mutant space of emergence and infinite formative capability could be supported. The suggestions made here will hopefully contribute to extending applicability of evolutionary space generation in the field of space design. To derive the potential mutant forms from biological space, a preliminary study was conducted regarding the characteristics of evolutionary form generation. For the purpose of this study, three evolutionary perspectives of reproduction, mutation (variation) and selection were taken. First, the theory of evolution was defined and characterized. Also, the relevance between the characteristics generated and hybrid mutant space was analyzed to consider relevant characteristics. The present study helped to understand that the hybrid mutant space had an evolutionary space structure based on a biological paradigm. It was also found that the mutant space structure built by mutant polymorphism assumed a systematic correlation between space and environment.

• 약학회지
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• 제50권6호
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• pp.386-392
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• 2006

Pramlintide, a synthetic analogue of human hormone amylin, is the first of a new class of amylinomimetic compounds. Present study was undertaken to compile and analyze the clinical trials of pramlintide, and thereby to facilitate the design of the bridging study for the earlier introduction of the drug, which might be needed by diabetes patients in Korea. Sixty-two articles from Pubmed and MEDLINE search were used to analyze the trials of pramlintide along with prescribing information and New Drug Application packet obtained form the manufacturer. The efficacy of the new drug was attributed to three mechanisms: delay of gastric emptying time, inhibition of post-prandial glucagon secretion, and reduction of food intake by enhanced satiety. Clinical trials consistently identified the effectiveness of the drug for the treatment of type 1and type 2 diabetes who have failed to achieve glycemic control despite optimal therapy with insulin. However, the six pivotal Phase III clinical trials were peformed with mostly caucasian and some black and hispanic people. None of the trials documented the proportion of either Asian or Korean participants. Since Korean diabetes patients show different epidemiology and characteristics in their disease state, it appears that the bridging study of pramlintide should be designed in the level of full scale Phase III clinical trial along with pharmacokinetic and pbarmacodynamic studies.

• 한국조경학회지
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• 제28권1호
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• pp.70-82
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• 2000

This is a study to generate a theoretical base for the development of wildlife corridor as a solution to the problems of wildlife population size reduction and declining bio-diversity resulting from the fragmented habitats caused by road constructions. This study seeks to examine and define techniques in very aspect of wildlife corridor including planning, site selection, design and development, and maintenance through an actual application. The results of this study are as follows. 1) The wildlife corridor should be developed in an approach supplementing a landscape ecological approach and a restoration ecological approach bilaterally. To this end, systematic methodology and process are required. 2) It was restored an ecosystem as close as possible go to the forest ecosystem before road development. In addition, in order to allow it to function as an ecological corridor, topography restoration, stream development, and ecological plantation were implemented. 3) The result of monitoring activities that continued for one year since the development confirmed the migration and inhabitation of a number of animals including small mammals. It is judged that it functions as a corridor in fragmented habitats as initially expected. 4) Through continuous monitoring in the future, the effects of corridor development on ecological restoration need to be reviewed in a long-term perspective. There is also a need to develop and refine a comprehensive maintenance plan for wildlife corridors and their surroundings. Based on such study results, actual data on the development of wildlife corridor should be accumulated. In follow-up studies, after continuous monitoring for a long period of time, the effects of wildlife corridor development should be evaluated comprehensively and wildlife corridor applicable to Korea should be standardized by correcting disclosed problems.

• 대한통합의학회지
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• 제9권1호
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• pp.141-150
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• 2021

Purpose : The purpose of this study was to investigate the effect of case-based learning application in human growth development classes on nursing students' problem-solving ability, self-directed learning ability, and academic self-efficacy. Methods : The research method was a self-report questionnaire before and after case-based learning for second-year nursing students who took the human growth development course at U University in K city. The collected data were statistically processed using SPSS WIN 21.0. Results : The results of the study showed that after case-based learning, problem-solving ability, self-directed learning ability, and academic self-efficacy were all significantly improved. In addition, as a result of examining the correlation between each variable after case-based learning, problem solving ability score and self-directed learning ability score (r=.54, ｐ<.01), and problem solving ability scores and academic self-efficacy scores (r=.44, ｐ<.01), were significantly correlated with self-directed learning ability scores and the academic self-efficacy reduction scores (r=.76, ｐ<.01). Conclusion : The results of this study suggested the need for various learning programs such as case-based learning to improve nursing students' problem-solving abilities and self-directed learning abilities and their application. In addition, to improve the learning self-efficacy of nursing students, a continuous and systematic study is suggested to develop and apply customized educational programs according to the learners' preferences. Since the sample group in this study was limited to one university, there were few cases and no control group, so there are limitations in generalizing the test effect, However, significant differences a were verified in the case-based learning pre-tests and post-tests.

• 지식경영연구
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• 제14권5호
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• pp.15-34
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• 2013

In a turbulent environment, it is important for a firm to obtain competitiveness through acquiring new technologies and new knowledge. Many studies has shown that R&D has positive effects on innovation and performance. However, the limitation of resources and research personnel for SMEs leads to the needs of collaboration between government R&D and SMEs. The quantitative results of government R&D comes in the form of patents or publication of papers while the qualitative results comes in the form of commercialization (revenue increase or cost reduction) of the SMEs acquiring the technology through technology transfer. Korean government invested 16.9 Trillion Won in 2013 and achieved remarkable quantitative results but the qualitative results are still yet to be improved. The technology transfer rate in 2011 was 26.0% while the success rate of commercialization of the transferred technology is only 23.6%. Therefore it is meaningful to study the success factors of the technology commercialization in Korea. In this study, a case of technology commercialization between ETRI and Initech is studied. Initech was a venture firm which started in 1997 with 2 employees and after transfer of technology from ETRI in 1999, it has grown to a firm of 238 employees. In this study, Jolly's commercialization model was used to analyze the success factors of the commercialization. It was shown that four main factors that leads to the success are (1) mobilizing interest and endorsement through customer oriented R&D by ETRI, (2) mobilizing resources for demonstration through systematic technology commercialization process by ETRI, (3) mobilizing market constitutents through government standardization that leads to the reliability of the participants, and (4) mobilizing complementary assets for delivery by management strategies of Initech.

• 한국치위생학회지
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• 제17권3호
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• pp.395-404
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• 2017

Objectives: The purpose of this study was to identify the effects of music intervention on the patient's fear and anxiety during scaling. Methods: 360 patients who had visited W University dental hygiene laboratory were selected as study subjects and divided into experiment group and control group. Results: Study results showed that the control group (71.9%) and the experimental group (75.1%) had experiences avoiding dental treatment due to fear. In the control group (37.6%) and experimental group (40.6%), the highest influencing factor was the sound of machine and followed by pain. The experimental group preferred classical music, followed by pop songs, trot music and instrumental music. In the experimental group (83.3%), fear and anxiety were alleviated by music, and 77.9% of the patients mentioned they would recommend music for scaling to other patients. There was an interaction effect (p=0.014) between the groups before and after the measurement of the lowest blood pressure. There was a significant difference in pulse before and after pulse measurement (p=0.000). There was a significant difference in respiration between groups (p=0.042) and before and after respiration (p=0.030). Conclusions: Study results showed that music intervention that utilizes music during scaling showed significant effects on the alleviation of fear and anxiety, affecting Pulse number among vital signs. Therefore, more systematic program is to be required to alleviate dental fear and anxiety with music therapy not only for scaling, but also for dental clinic in the future.

• 한국인구학
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• 제11권1호
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• pp.14-31
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• 1988

The national family planning program in Korea, which was instituted as an integral part of the nation's economic development plans since 1962, has contributed greatly to a reduction in the fertility and population growth rate. The total fertility rate dipped from 6.0 births per women in 1960 to 2.0 in 1985, and the population growth rate rom 2.84 percent per year to 1.25 percent during the same period, while the contraceptive practice rate for the 15-44 married women increased from 9 percent in 1965 to 70 percent in 1985. Study findings indicate that the fertility reduction in the past 26 years is largely attributed to the virgorous implementation of the national family planning program, rising age at marriage, wide-spread use of induced abortion, and the changes in attitude regarding the value of children that came into being in the wake of the rapid socio-economic development over the period. Among the strengths of the national family planning program are the following : 1) a pluralistic system of program manageent with active participation of various government and voluntary organizations, 2) utilization of a large corps of family planning field workers to conduct face-to-face communication and motivation activities, 3) use of private physicians with government support to provide contraceptive services, 4) a systematic program management system including program planning of traget allocation, evaluation, and supervision with a broad MIS and award system, 5) numerous incentive and disincentive schemes for stimulating the small family norm and contraceptive use, and 6) strong commitments to the family planning program by political leaders. The new demographic targets during the Sixth Five-Year Economic and Social Development plan period(1987-91) have been set for a further reduction in the population growth rate to 1.0 percent by 1993, assuming that the TFR will decline to 1.75 level in 1995. This target is, however, not easy to achieve due to anticipated unfavorable factors like the strong boy preference, high discontinuation rates of reversible contraceptive methods, fertility termination-oriented contraceptive use, a plateau level of contraceptive practice rate that has mostly accounted for a sterilization, shortened length of birth intervals, and the changing patterns of contraceptive mix. The recent changes in contraceptive and fertility behaviors clearly indicate that the past quantity-oriented management system of the national program should be redirected toward a quality-oriented approach. Particularly, program efforts should be expanded to recruit new contraceptive users in the 20s of younger age groups, both for birth spacing and controlling their fertility since the women aged 20 to 29 account for more than 80 percent of the total annual births in recent years. In addition, the current contraceptive fee system of the national family planning program should be gradually shifted from free contraceptive services to a acceptor's charge system, and the provision of contraceptive services through the medical insurance system, which will cover the entire population by 1989, should be accelerated as a means of integration of family planning program with other health programs.

• 한국산학기술학회논문지
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• 제17권11호
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• pp.271-284
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• 2016

본 연구는 임부의 산전우울에 대한 인지행동치료 중재의 효과를 검증하기 위해 수행된 체계적 문헌고찰 및 메타분석 연구이다. 데이터베이스는 CINAHL, PubMed, EMBASE 및 Koreamed, 국회도서관, 한국학술정보(Korean studies Information Service System, KISS), 한국의학논문데이터베이스 등 국내외 domain을 활용하였다. 검색은 ((Perinatal OR Antenatal OR Antepartum OR Pregnant) AND Depression) AND Women AND (CBT OR (Cognitive behavioral AND (Therapy OR Treatment)))와 '산전우울', '임부', '인지행동치료' 등의 검색어로 2016년 5월까지 출판된 문헌을 검토하였다. 분석은 R을 이용한 임의효과모형을 적용하여 산전우울과 불안의 효과크기를 각각 산출하였으며, 효과크기의 이질성을 검증하기위해 메타 ANOVA를 활용하여 조절효과분석을 실시하였다. 그리고 funnel plot, Egger's regression test, fail-safe N, trim-and-fill 분석을 활용한 출간오류분석과 민감성 분석을 실시하여 전체 연구 결과의 타당성을 검증하였다. 연구결과 총 180편의 문헌이 검색되었으며, 선택배제기준에 따라 최종적으로는 clinical trials 16편을 분석하였다. 분석에 포함된 개별문헌은 Scottish Intercollegiate Guideline Network (SIGN)의 checklist를 통해 비뚤림 위험을 평가하였으며, 대체로 비뚤림 위험은 낮았다. 연구결과 본 연구에서 중재의 산전우울에 대한 효과크기는 Hedges' g=-0.55(95% CI: -0.76~-0.33)로 통계적으로 유의하게 낮았으며, 불안에 대한 효과크기는 Hedges' g=-0.20(95% CI: -0.48~-0.08)이었으나, 통계적으로 유의한 차이는 없었다. 문헌의 이질성, 출판오류의 위험성 등은 낮았다. 본 메타분석결과에 의하면 인지행동치료는 임신부의 산전우울 증세 완화에 보통 정도의 효과가 있음이 밝혀졌다.

• 에너지공학
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• 제11권1호
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• pp.18-25
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• 2002

침부식 (FAC, Flow-Accelerated Corrosion)에 의한 감육 문제는 원자력 발전소 배관관리에 있어서 매우 중요하다. 특히 FAC는 배관 내부 유체의 pH, 용존산소 농도, 유체 온도, 유속 및 습증기 분율 등과 배관의 형상 및 재료 등의 특정 조건에서만 발생하므로, FAC 문제를 관리하기 위해서는 체계적인 접근이 필요하다. 본 연구에서는 국내 특정 CANDU원전의 2차계통 배관을 대상으로 관련 데이터베이스 구축, 구축된 데이터베이스를 이용한 FAC감육율의 예측 및 배관 잔여수명의 평가 등을 수행하였다. 또한 FAC 발생기구 및 FAC에 영향을 주는 요인에 대해서도 조사하였다. 습분분리기와 플래시탱크 사이 배관 라인의 해석 예로부터 FAC 문제를 관리하는 방안을 제시하였다. 제시된 방안은 국내 다른 원자력발전소의 배관 관리에도 활용될 수 있을 것이다.

• 패션비즈니스
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• 제14권3호
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• pp.35-51
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• 2010

This study aims at providing data for establishing a marketing strategy which can enhance the competitiveness of Korea domestic SPA(Specialty Store Retailer of Private Label Apparel) Brands by suggesting countermeasure strategy through the observation and analysis for SPA Brands, under the current circumstance in which the systematic and scholastic discussion for the matter, is lack, despite the diastrophism in fashion industry is prospected according to the rapid growth of Global SPA Brands. For this purpose, the characteristic and current status of Global SPA Brands is examined, and the main cause of growth is analyzed by approaching to their marketing characteristic, in this study. In relation with this situation, this study suggests the provisions as below, which are drawn from the analysis on Global SPA Brands' marketing strategy, so that Korea domestic SPA Brands could achieve successive performance under fierce competition. First, to be a competitive SPA Brands a business should be able to supply products with frequent product turnover by an interval level of one week or so, the existent product planning by seasons, as a business obtains various swift informations on consumers' demand with R&D center foundation. Secondly, SPA Brands should establish a strategy that a business can create high net profit by inventory management which enables lowering inventory ratio remarkably, and a strategy for innovative product supply by small quantity batch production, along with founding a high technological logistics system. Third, SPA Brands should establish a strategy for primary cost reduction by overseas dispersed outsourcing in order to enable diverse product development and rational price setting. Fourth, fashion marketers should establish also a strategy for communication by which brand image can be delivered effectively, by firming the brand identity and by informing product characteristic and customer service totally, with the method of VMD and flagship store. Additionary, fashion marketers also should establish a strategy by developing mobile application which can provide brand image and diverse other fashion related information.