• 대한상한금궤의학회지
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• v.9 no.1
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• pp.85-99
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• 2017

Objective : The objective of this study is to define the conceptional meaning of Shanghanlun provision while applying Shanghanlun disease pattern identification diagnostic system. Methods : 2 clinical cases, whose patients were treated by Injinho-tang, which was selected according to Shanghanlun provisions dualized with Je-Gang(提綱) and Jo-Moon(條文), were analyzed. Results : According to the results of analysis of 2 cases, the patients' diseases were improved when the treatment was applied according to Shanghanlun disease pattern identification diagnostic system and the interpretation of Shanghanlun provisions according to the etymology of Chinese character. Conclusions : These results suggests that Shanghanlun provisions be applied according to etymological interpretation of Chinese character in Shanghanlun disease pattern identification diagnostic system.

• The Journal of Internal Korean Medicine
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• v.40 no.5
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• pp.752-759
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• 2019

Objective: The purpose of this case study was to report the effect of Korean medicine treatment on a patient diagnosed with a nasal polyp. Methods: A 62-year-old female patient with a nasal polyp visited the clinic sixteen times from September 11th, 2018 to December 18th, 2018. The patient was treated with Eunhwayeongyo-tang, Haeyeol-tang, Hongsamkyungok-go extract, and acupuncture during the treatment period. We evaluated the improvement of symptoms by nasoendoscopy. Results: After the Korean medicine treatment, the nasal polyp was completely eradicated. Hyperemia of the nasal mucous membrane and rhinorrhea were also relieved. Conclusion: The study findings suggested that Korean medicine treatment (Eunhwayeongyo-tang, Haeyeol-tang, and Hongsamkyungok-go extract, and acupuncture) might be effective for treatment of patients diagnosed with nasal polyps.

• 대한상한금궤의학회지
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• v.11 no.1
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• pp.83-94
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• 2019

Objective : There was an improvement in a patient with psoriasis following the intake of Hoeyeok-tang for 317 days. By analyzing these cases, we reviewed the use of Hoeyeok-tang in skin diseases and attempted to interpret the related Shanghanlun articles. Methods : The diagnostic process was analyzed according to the disease pattern identification diagnostic system based on the Shanghanlun provisions. The progression of psoriasis, which was addressed, was assessed using the PASI score. Results : The patient was diagnosed with Soeum-byung 324, and the PASI score decreased from 13.6 to 0.4 after the intake of Hoeyeok-tang for 317 days. The patient's compliance and expectation from treatment were good, and no specific adverse effect was identified. Conclusions : This study suggests the clinical use of Hoeyeok-tang in psoriasis based on Shanghanlun.

• 대한상한금궤의학회지
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• v.10 no.1
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• pp.69-80
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• 2018

Objective : Patients complaining of dizziness and olfactory hallucination who were diagnosed and treated with the Shanghanlun disease pattern identification diagnostic system were analyzed to report cases. Methods : This is a case report on a patient who has been suffering from Dizziness andolfactory hallucination. According to Diagnostic system based on Shanghanlun provisions, Gyeji-tang was provided. The severity of Dizziness was evaluated by NRS. Results : When analyzing the patient's history and symptoms, it can be found in article No. 42 in Shanghanlun. In the first case, NRS changed from 8 to 2. In the second case, NRS change 8 to 1. Conclusions : Gyeji-tang can be effective in dizziness and olfactory hallucination with the Shanghanlun disease pattern identification diagnostic system.

• International Journal of Advanced Culture Technology
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• v.11 no.3
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• pp.172-181
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• 2023

Dunhuang murals are one of the most outstanding achievements in the art of traditional grotto painting in China, and are known as a "Wall Museum". As a representative of the heyday of Dunhuang murals, an in-depth exploration of Dunhuang murals from the perspective of color will help researchers understand the laws and connotations of color in Dunhuang murals during the Tang Dynasty and fully grasp the art of Dunhuang murals. The color system of the traditional Chinese "Five colors" concept expresses the cultural attributes and emotions of the Chinese people and has distinctive national characteristics. This thesis provides a theoretical grasp of the traditional Chinese "Five colors" view of color system, the Dunhuang murals of the Tang Dynasty, and the color configuration of the color composition principles, and uses the modern design principles of color composition to conduct an in-depth analysis of the configuration of the Dunhuang murals' use of color. Explore the unique characteristics of Tang Dynasty Dunhuang murals, and help modern designers master richer color application techniques by learning from and studying the harmonious patterns of Dunhuang murals to provide a new path for the dissemination of excellent Chinese traditional culture.

• The Journal of Internal Korean Medicine
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• v.32 no.1
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• pp.10-25
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• 2011

Objectives : Asthma is considered an inflammation disease characterized by airway hyperresponsiveness and pulmonary eosinophilia. Chungsang boha-tang is a herbal medication which has been frequently used in traditional therapeutic agents for asthma. We aimed to observe the clinical effects of Chungsangboha-tang on blood eosinophil, serum IgE, AST, ALT and pulmonary function in asthmatic outpatients. Methods : The subjects consisted of 66 asthmatic patients who had been treated with Chungsangboha-tang among all the asthmatic patients who visited the 5th Internal Medicine of the Oriental Medicine Hospital of Kyung Hee University from November,2004 to November,2009. We observed blood eosinophil, serum IgE, AST, ALT levels and pulmonary function test results as well as medical records of patients to evaluate the effects. Results : Pulmonary function significantly improved after 8 weeks of treatment, and blood eosinophil and serum IgE level significantly decreased after 8 weeks of treatment. AST, ALT levels changed in normal ranges. Chungsangboha-tang was significantly effective on the male patients who had a smoking history and worse initial lab findings. We also observed a significant improvement of pulmonary function and decrease of eosinophil and serum IgE levels in the patient group who had a single treatment of Chungsangboha-tang without steroid therapy. Conclusions : This study shows that Chungsangboha-tang has effects on the improvement of pulmonary function and decrease of eosinophil and serum IgE levels as well as improvement of symptoms. And, 8 weeks of long-term treatment showed no negative effects such as significant increase of AST, ALT levels.

• The Journal of Internal Korean Medicine
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• v.29 no.2
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• pp.334-347
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• 2008

Background and Objective : Haeyeol-tang, composed of Houttuyniae Herba, Lonicerae Flos, Taraxaci Herba, and Scrophulariae Radix, is widely used for alleviating the symptom of various kinds of inflammatory pulmonary disease, including asthma and COPD. We want to know whether Haeyeol-tang has an anti-inflammatory effect by analyzing expression of pro-inflammatory cytokines. Materials and Methods : We differentiated the THP-1 cells into macrophage-like cells by treatment with PMA. Inflammation was induced by treatment with LPS and PMA. We found the safe concentration of Haeyeol-tang by using MTS assay and used PD98059 as a negative control for comparison of anti-inflammatory effect of Haeyeol-tang. Results : The RT-PCR analysis results show that the cell survival rate is over 100% within 1 ng/mL to 1 ug/mL of Haeyeol-tang and begins to decrease under 100% at 10 ug/mL. The gene expression of $IL-1{\beta}$, IL-6, IL-8, IL-10, $TNF-{\alpha}$ and $TGF-{\beta}$ levels were down-regulated when Haeyeol-tang was treated at concentrations between 1 ng/mL an 1 ug/mL on monocyte-derived macrophages. Interestingly, 1 ug/mL Haeyeol-tang-treated samples showed that the transcriptional activities of IL-8, $TNF-{\alpha}$, IL-10 and $TGF-{\beta}$ were more down-regulated than those of PD098059 $(TNF-{\alpha}$ inhibitor). At protein level, the ELISA analysis results showed that there were more remarkable (p<0.001) decreases in expression of $IL-1{\beta}$, IL-6, IL-8 and $TNF-{\alpha}$ on both the 1 ug/mL Haeyeol-tang-treated group and the PD98059-treated group than the LPS-treated group. Conclusion : We conclude that Haeyeol-tang has an anti-inflammatory effect by inhibiting expression of pro-inflammatory cytokines and chemokines at mRNA and protein levels. These results may provide us a promising way to care for general inflammatory diseases as well as inflammatory pulmonary disease, including asthma and COPD, with further clinical study.

• The Journal of Internal Korean Medicine
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• v.32 no.4
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• pp.497-503
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• 2011

Objectives : To assess the effect of Bojungiki-tang for symptomatic management in stable asthmatic patients after initial treatment. Methods : Outcome measures of asthmatic patients were recorded using patient's charts and inquiry. Compared with the patient's state right after they got their treatment, "Excellent" was if it was almost the same state, "Good" was if the patient's state was maintained for almost 70%, "Fair" was for 50%, "Poor" was for under 50% or if the patient required another treatment. Results : Of 25 patients, 21 used Bojungiki-tang for more than one month and 20 maintained a stable state, that is, feeling more than 70% of symptom control compared with previous best status. Conclusions : Bojungiki-tang has a good effect for maintaining asthma after treatment.

• 대한상한금궤의학회지
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• v.15 no.1
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• pp.117-130
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• 2023

Objective : The objective of this study is to explore the meaning of 弦 in Shanghanlun through analyzing two cases. Methods : Two cases treated with modified Soshiho-tang, which is administrated when 弦 aggravates chief complaints, were analyzed. All of the cases were diagnosed by disease pattern identification diagnostic system based on Shanghanlun Provisions. Results : The patients' chief complaints of all 2 cases were improved after administration of modified Soshiho-tang. As pulling symptom was reduced in all 2 cases, patients' disease were relieved. Through the etymological research and clinical treatment results, the clinical meaning of 弦 is deduced as 'pulling'. Conclusions : The etymological and clinical analysis suggest that the concept of '弦' maybe defined as 'pulling' in Shanghanlun.

• The Journal of Korean Medicine
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• v.29 no.4
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• pp.123-132
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• 2008

Objective: In this study, the author tried to investigate whether revised Seonbangpaedok-tang (SPT) and Sigyeongcheongpye-tang (SCT) significantly effects both PMA-induced mucin production and MUC5AC gene expression from airway epithelial cells. Objective: In this study, the author tried to investigate whether revised Seonbangpaedok-tang (SPT) and Sigyeongcheongpye-tang (SCT) significantly affects both PMA-induced mucin production and MUC5AC gene expression from airway epithelial cells. Materials and Methods: Confluent NCI-H292 cells were pretreated for 30 min in the presence of SPT and SCT and treated with PMA (10 ng/$m{\ell}$), to assess the effects of the agents on PMA-induced mucin production by enzyme-linked immunosorbent assay (ELISA). Also, the effects of the agents on PMA-induced MUC5AC gene expression from the same cells were investigated. Possible cytotoxicities of the agent were assessed by measuring the rate of survival and proliferation of NCI-H292 cells after treatment of agents during 48 hrs. Results: (1) SPT and SCT did not show significant cytotoxicity to NCI-H292 cells; (2) SPT significantly inhibitedthe expression levels of PMA-induced MUC5AC gene in NCI-H292 cells. SCT slightly decreased the expression levels of PMA-induced MUC5AC gene; (3) SPT significantly decreased PMA-induced mucin production from NCI-H292 cells. However, SCT did not affect mucin production. Conclusion: Theseresults suggest that SPT can not only affect the production of mucin but also the expression of the mucin gene and this explains the traditional use of SPT in oriental medicine. The effects of SPT and SCT with their components should be further investigated using animal experimental models that reflect pathophysiology of airway diseases via ongoing studies.