• Title/Summary/Keyword: Survival time estimation

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Logistic Regression Method in Interval-Censored Data

  • Yun, Eun-Young;Kim, Jin-Mi;Ki, Choong-Rak
    • The Korean Journal of Applied Statistics
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    • v.24 no.5
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    • pp.871-881
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    • 2011
  • In this paper we propose a logistic regression method to estimate the survival function and the median survival time in interval-censored data. The proposed method is motivated by the data augmentation technique with no sacrifice in augmenting data. In addition, we develop a cross validation criterion to determine the size of data augmentation. We compare the proposed estimator with other existing methods such as the parametric method, the single point imputation method, and the nonparametric maximum likelihood estimator through extensive numerical studies to show that the proposed estimator performs better than others in the sense of the mean squared error. An illustrative example based on a real data set is given.

Estimation of Survival Rates in Patients with Lung Cancer in West Azerbaijan, the Northwest of Iran

  • Abazari, Malek;Gholamnejad, Mahdia;Roshanaei, Ghodratollah;Abazari, Reza;Roosta, Yousef;Mahjub, Hossein
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.9
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    • pp.3923-3926
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    • 2015
  • Background: Lung cancer is a fatal malignancy with high mortality and short survival time. The aim of this study was to estimate survival rates of Iranian patients with lung cancer and its associate predictive factors. Materials and Methods: The study was conducted on 355 patients admitted to hospitals of West Azerbaijan in the year 2007. The patients were followed up by phone calls until the end of June 2014. The survival rate was estimated using the Kaplan-Meier method and log-rank test for comparison. The Cox's proportional hazard model was used to investigate the effect of various variables on patient survival time, including age, sex, Eastern Cooperative Oncology Group (ECOG) performance, smoking status, tumor type, tumor stage, treatment, metastasis, and blood hemoglobin concentration. Results: Of the 355 patients under study, 240 died and 115 were censored. The mean and median survival time of patients was 13 and 4.8 months, respectively. According to the results of Kaplan-Meier method, 1, 2, and 3 years survival rates were 39%, 18%, and 0.07%, respectively. Based on Cox regression analysis, the risk of death was associated with ECOG group V (1.83, 95% CI: 1 Conclusions: The survival time of the patients with lung cancer is very short. While early diagnosis may improve the life expectancy effective treatment is not available.

Estimation of Survival Function and Median Survival Time in Interval-Censored Data (구간중도절단자료에서 생존함수와 중간생존시간에 대한 추정)

  • Yun, Eun-Young;Kim, Choong-Rak
    • The Korean Journal of Applied Statistics
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    • v.23 no.3
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    • pp.521-531
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    • 2010
  • Interval-censored observations are common in medical and epidemiologic studies; however, limited studies exist due to the complexity and special structure of interval-censoring. This paper introduces the imputation method and the self consistency method in the interval-censored data. We propose a new method of generating random numbers under an interval-censoring set-up. Through simulation studies we compare two methods under various simulation schemes in the sense of the mean squared error for estimating the median survival time and the mean integrated squared error for estimating the survival function. Under a moderate censoring percentage, the mean imputation method showed a better performance than the self-consistency method in estimating the median survival time and the survival function.

Estimation of the Survival Function under Extreme Right Censoring Model (극단적인 오른쪽 관측중단모형에서 생존함수의 추정)

  • Lee, Jae-Man
    • Journal of the Korean Data and Information Science Society
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    • v.11 no.2
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    • pp.225-233
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    • 2000
  • In life-testing experiments, in which the longest time an experimental unit is on test is not a failure time, but rather a censored observation. For the situation the Kaplan-Meier estimator is known to be a baised estimator of the survival function. Several modifications of the Kaplan-Meier estimator are examined and compared with bias and mean squared error.

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Change-Point Estimation and Bootstrap Confidence Regions in Weibull Distribution

  • Jeong, Kwang-Mo
    • Journal of the Korean Statistical Society
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    • v.28 no.3
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    • pp.359-370
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    • 1999
  • We considered a change-point hazard rate model generalizing constant hazard rate model. This type of model is very popular in the sense that the Weibull and exponential distributions formulating survival time data are the special cases of it. Maximum likelihood estimation and the asymptotic properties such as the consistency and its limiting distribution of the change-point estimator were discussed. A parametric bootstrap method for finding confidence intervals of the unknown change-point was also suggested and the proposed method is explained through a practical example.

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Estimation for a bivariate survival model based on exponential distributions with a location parameter

  • Hong, Yeon Woong
    • Journal of the Korean Data and Information Science Society
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    • v.25 no.4
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    • pp.921-929
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    • 2014
  • A bivariate exponential distribution with a location parameter is proposed as a model for a two-component shared load system with a guarantee time. Some statistical properties of the proposed model are investigated. The maximum likelihood estimators and uniformly minimum variance unbiased estimators of the parameters, mean time to failure, and the reliability function of system are obtained with unknown guarantee time. Simulation studies are given to illustrate the results.

Target Birth Intensity Estimation Using Measurement-Driven PHD Filter

  • Zhang, Huanqing;Ge, Hongwei;Yang, Jinlong
    • ETRI Journal
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    • v.38 no.5
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    • pp.1019-1029
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    • 2016
  • The probability hypothesis density (PHD) filter is an effective means to track multiple targets in that it avoids explicit data associations between the measurements and targets. However, the target birth intensity as a prior is assumed to be known before tracking in a traditional target-tracking algorithm; otherwise, the performance of a conventional PHD filter will decline sharply. Aiming at this problem, a novel target birth intensity scheme and an improved measurement-driven scheme are incorporated into the PHD filter. The target birth intensity estimation scheme, composed of both PHD pre-filter technology and a target velocity extent method, is introduced to recursively estimate the target birth intensity by using the latest measurements at each time step. Second, based on the improved measurement-driven scheme, the measurement set at each time step is divided into the survival target measurement set, birth target measurement set, and clutter set, and meanwhile, the survival and birth target measurement sets are used to update the survival and birth targets, respectively. Lastly, a Gaussian mixture implementation of the PHD filter is presented under a linear Gaussian model assumption. The results of numerical experiments demonstrate that the proposed approach can achieve a better performance in tracking systems with an unknown newborn target intensity.

GENERALIZED LINDLEY DISTRIBUTION USING PROPORTIONAL HAZARD FAMILY AND INFERENCE OF FAILURE TIME DATA

  • Ahmed AL-Adilee;Hawraa A. AL-Challabi;Hassanein Falah;Dalael Saad Abdul-Zahra
    • Nonlinear Functional Analysis and Applications
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    • v.28 no.3
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    • pp.793-800
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    • 2023
  • In this paper, we propose a generalization of Lindley distribution (GLD) via a special structure that is concern with progressively Type-II right censoring and time failure data. We study the modern properties that we have built by such combination, for example, survival function, hazard function, moments, and estimation by non-Bayesian methods. Application on some selected data related to Lindley distribution (LD) and (ED) have been employed to find out the best distribution that can fit data comparing with the GLD.

A Study on Simple Calculation Method of Survival Time for Damaged Naval Ship Due to the Explosion (폭발에 의해 손상된 함정의 생존시간 간이계산법 연구)

  • Kim, Jae-Hyun;Park, Myung-Kyu
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.10 no.4
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    • pp.211-217
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    • 2007
  • Due to advanced new weapons and changes in the combat environment, survivability improvement methods for naval ship design have continuously evolved. Surface naval ships are easily detected by the enemy and, moreover, there are many attack weapons that may be used against surface naval ships. Therefore, it is important for modem naval ships, especially combat naval ships, to ensure survivability. In order to design a naval ship considering survivability, the designers are required to establish reasonable attack scenarios. An explosion may induce local damage as well as global collapse of the ship. Therefore, possible damage conditions should be realistically estimated at the design stage. In this study, an ALE technique was used to simulate the explosion analysis, and the survival capability of damaged naval ships was investigated. Especially, the author have establish the simple method of estimation of survival time for damaged naval ships.

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Estimation of the Cure Rate in Iranian Breast Cancer Patients

  • Rahimzadeh, Mitra;Baghestani, Ahmad Reza;Gohari, Mahmood Reza;Pourhoseingholi, Mohamad Amin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.12
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    • pp.4839-4842
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    • 2014
  • Background: Although the Cox's proportional hazard model is the popular approach for survival analysis to investigate significant risk factors of cancer patient survival, it is not appropriate in the case of log-term disease free survival. Recently, cure rate models have been introduced to distinguish between clinical determinants of cure and variables associated with the time to event of interest. The aim of this study was to use a cure rate model to determine the clinical associated factors for cure rates of patients with breast cancer (BC). Materials and Methods: This prospective cohort study covered 305 patients with BC, admitted at Shahid Faiazbakhsh Hospital, Tehran, during 2006 to 2008 and followed until April 2012. Cases of patient death were confirmed by telephone contact. For data analysis, a non-mixed cure rate model with Poisson distribution and negative binomial distribution were employed. All analyses were carried out using a developed Macro in WinBugs. Deviance information criteria (DIC) were employed to find the best model. Results: The overall 1-year, 3-year and 5-year relative survival rates were 97%, 89% and 74%. Metastasis and stage of BC were the significant factors, but age was significant only in negative binomial model. The DIC also showed that the negative binomial model had a better fit. Conclusions: This study indicated that, metastasis and stage of BC were identified as the clinical criteria for cure rates. There are limited studies on BC survival which employed these cure rate models to identify the clinical factors associated with cure. These models are better than Cox, in the case of long-term survival.