• Title/Summary/Keyword: Sub-channels

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Homer2 regulates amylase secretion via physiological calcium oscillations in mouse parotid gland acinar cells

  • Kang, Namju;Kang, Jung Yun;Shin, Dong Min;Yang, Yu-Mi
    • International Journal of Oral Biology
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    • v.45 no.2
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    • pp.58-63
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    • 2020
  • The salivary glands secrete saliva, which plays a role in the maintenance of a healthy oral environment. Under physiological conditions, saliva secretion within the acinar cells of the gland is regulated by stimulation of specific calcium (Ca2+) signaling mechanisms such as increases in the intracellular Ca2+ concentration ([Ca2+]i) via storeoperated Ca2+ entry, which involves components such as Orai1, transient receptor potential (TRP) canonical 1, stromal interaction molecules, and inositol 1,4,5-triphosphate (IP3) receptors (IP3Rs). Homer proteins are scaffold proteins that bind to G protein-coupled receptors, IP3Rs, ryanodine receptors, and TRP channels. However, their exact role in Ca2+ signaling in the salivary glands remains unknown. In the present study, we investigated the role of Homer2 in Ca2+ signaling and saliva secretion in parotid gland acinar cells under physiological conditions. Deletion of Homer2 (Homer2-/-) markedly decreased the amplitude of [Ca2+]i oscillations via the stimulation of carbachol, which is physiologically concentrated in parotid acinar cells, whereas the frequency of [Ca2+]i oscillations showed no difference between wild-type and Homer2-/- mice. Homer2-/- mice also showed a significant decrease in amylase release by carbachol in the parotid gland in a dose-dependent manner. These results suggest that Homer2 plays a critical role in maintaining [Ca2+]i concentration and secretion of saliva in mouse parotid gland acinar cells.

Discussion to Spatial Characteristics on a Sub-tidal Benthic Community Composed to the Complicated Coastal Lines Around Tongyeong, Korea (복잡한 해안선 구조를 가진 통영 해역에서 조하대 저서생물 군집의 공간특성 비교)

  • Yoon, Kon-Tak;Jung, Yun-Hwan;Kang, Rae-Seon
    • Ocean and Polar Research
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    • v.32 no.2
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    • pp.123-135
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    • 2010
  • Around Tongyeong coasts which located in southern coast of Korea composed to the complex coastal line and scattered by small islands. It also has been distributed to a complicated bathymetric structure by several types of channels. This study carried to analyze the spatial characteristics of macrobenthic community and benthic environmental variance on sub-tidal area based on multivariate statistics tools. Sediment composition varied from muddy sand to mud, and along the channels, it composed to a heterogeneous bottoms mixed by shell fragment, cobbles and mud. Organic contents on the surface sediment varied 1.1-3.9%. Total of 272 species, $33,349\;ind./m^2$ of macrobenthos identified in all of sample area. Polychaetes also prevailed among the specimen. L. longifolia, P. pinnata dominated based on density. Considering on the biomass, echinoderm S. lacunosa, A. tricoides listed. Closer to the coastal area, the density and diversity were higher. Community structure based on cluster analysis was discriminated into three groups. Each group was also characterized by geographical state such as depth, sediment composition. In addition, when applied to the bathymetric data, the channel, which composed to the mixed sediment, made a role of limited factor which characterized to benthic community. Because the specimen around the channel have been affected on the diverse sediment mixture. Most of benthic studies in the southern coast of Korea focused to the condition of benthic organic pollution spatially, because along the coast, it also developed a aquaculture ground and industrial complex. But, as results, most of the area, it turn out the less polluted areas nevertheless similar environment situation. It supposed that benthic community affect to the bottom sediment composition by physical characteristics.

Improved Code Timing Estimator for DS-CDMA Systems Using Correlated Antennas in Time-Varying Fading Channels (시변 페이딩 채널에서 상관관계가 있는 안테나를 사용하는 DS-CDMA 통신 시스템을 위한 개선된 최대가능도 코드 타이밍 추정기)

  • Kim Sang-Choon;Jeong Bong-Sik
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.10 no.5
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    • pp.910-920
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    • 2006
  • We consider the problem of estimating a code-timing of DS-CDMA signal in antenna array systems in the presence of flat fading channels and near-far environments. We derive an approximate maximum likelihood algorithm of estimating the code-timing of a desired user for DS-CDMA systems to better utilize the time-varying characteristics of the fading process. In the development of code timing estimator, the given observation bits are divided into many sets of sub-windows with each sufficiently large. The proposed method uses sub-windows with equal size associated with the coherence time of channel fading. The alternative approach is that without the estimation of the fading rate, the sufficiently given observation bits are simply separated into two consecutive sets of sub-windows. The derivation of the proposed algorithms is based on multiple antennas partially correlated in space. The impacts of spatial fading correlation on acquisition and men acquisition time performance of the proposed algorithms are also examined.

An Experimental Study on Flow Boiling Heat Transfer within Horizontal Rectangular Channels with Small Heights (미세 수평 사각 유로에서의 비등 열전달에 대한 실험적 연구)

  • Lee, Sang-Yong;Lee, Han-Ju
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.9
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    • pp.1209-1218
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    • 2001
  • The present paper proposes a new correlation for the flow boiling heat transfer coefficients in the low flow rate condition (Re(sub)LF$\leq$200) within horizontal rectangular channels with small gaps (heights). The gap between the upper and the lower plates of each channel ranges from 0.4 to 2mm while the channel width being fixed to 20mm. Refrigerant 113 was used as the test fluid. The mass flux ranges from 50 to 200kg/㎡s and the channel walls were uniformly heated with the heat flux range of 3-15kW/㎡. The quality range covers from 0.19 to 0.76 and the flow pattern is considered to be annular. The measured heat transfer coefficients increase with the mass flux and the local quality; however the effect of the heat flux appears to be minor. At the low mass flux condition, which is more likely with the smaller gap size, the heat transfer is primarily controlled by the liquid film thickness. The proposed F factor for the heat transfer coefficient in the range of Re(sub)LF$\leq$200 well represents the experimental data within the deviation of $\pm$20%. The Kandlikars flow boiling correlation covers the higher flow-rate range(Re(sub)LF>200) within the deviation of $\pm$20%.

Hybrid-Feature Extraction for the Facial Emotion Recognition

  • Byun, Kwang-Sub;Park, Chang-Hyun;Sim, Kwee-Bo;Jeong, In-Cheol;Ham, Ho-Sang
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.1281-1285
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    • 2004
  • There are numerous emotions in the human world. Human expresses and recognizes their emotion using various channels. The example is an eye, nose and mouse. Particularly, in the emotion recognition from facial expression they can perform the very flexible and robust emotion recognition because of utilization of various channels. Hybrid-feature extraction algorithm is based on this human process. It uses the geometrical feature extraction and the color distributed histogram. And then, through the independently parallel learning of the neural-network, input emotion is classified. Also, for the natural classification of the emotion, advancing two-dimensional emotion space is introduced and used in this paper. Advancing twodimensional emotion space performs a flexible and smooth classification of emotion.

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Maximum Likelihood Receivers for DAPSK Signaling

  • Xiao Lei;Dong Xiaodai;Tjhung Tjeng T.
    • Journal of Communications and Networks
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    • v.8 no.2
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    • pp.205-211
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    • 2006
  • This paper considers the maximum likelihood (ML) detection of 16-ary differential amplitude and phase shift keying (DAPSK) in Rayleigh fading channels. Based on the conditional likelihood function, two new receiver structures, namely ML symbol-by-symbol receiver and ML sequence receiver, are proposed. For the symbol-by-symbol detection, the conventional DAPSK detector is shown to be sub-optimum due to the complete separation in the phase and amplitude detection, but it results in very close performance to the ML detector provided that its circular amplitude decision thresholds are optimized. For the sequence detection, a simple Viterbi algorithm with only two states are adopted to provide an SNR gain around 1 dB on the amplitude bit detection compared with the conventional detector.

Dynamic Sub-carrier Multiplexed channel allocation and efficient frame distribution scheme in optical access networks (광가입자망 SCM 채널 동적할당 및 효율적 프레임 분배 방안)

  • 김남욱;윤현호;김태연;유정주;김병휘;강민호
    • Proceedings of the IEEK Conference
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    • 2003.11c
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    • pp.113-116
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    • 2003
  • In this paper, we propose a dynamic parallel channel allocation mechanism that dynamically controls total number of allocation channels of each subscriber to effectively service user bandwidth demands while high utilization and fairness are guaranteed in WDM based optical access networks. The logical performance gain of statistical multiplexing by dynamic channel allocation is validated with analytic method as well as simulations. We also introduce the adaptive padding scheme in order to efficiently distribute forwarded frames to aggregated multi-link channels which are formed by parallel channel allocation mechanism. The proposed scheme shows the performance enhancement by minimizing unnecessary padding size and the processing time.

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A Study on Factors that Affect Impulse Purchase on Cable TV Home-shopping (Cable TV 홈쇼핑에서의 충동구매에 영향을 미치는 요인)

  • 이은희;종은영
    • Journal of Families and Better Life
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    • v.21 no.2
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    • pp.61-74
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    • 2003
  • Recently, the number of consumers who buy various goods using the shopping channels on cable TV has increased. The objectives of this study are to examine the propensity of consumers to make an impulse purchase through cable TV, and to investigate the factors that influence consumers' impulse purchase. The following was found in this study: (1) The propensity of consumers to make impulse purchases on cable TV is somewhat low, Among sub-areas of impulse purchase, the propensity to make impulse purchase by suggestion is the highest. (2) Among the variables that affect consumers' impulse purchase on cable TV, the most influential variable is the psychological factor, followed by the frequency of shopping on cable TV, positive testimony from consumers who have used the product, and the amount of time spent in watching shopping channels on cable TV, in that order.

Solvent-Assisted Soft-Lithographic Patterning of Lyotropic Liquid Crystalline Polymer Film by Flow Control through Patterned Channels

  • Park, Chang-Sub;Park, Kyung-Woo;Kang, Shin-Won;Kwak, Gi-Seop;Kim, Hak-Rin
    • 한국정보디스플레이학회:학술대회논문집
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    • 2009.10a
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    • pp.641-644
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    • 2009
  • We demonstrated a solvent-assisted soft-lithographic patterning method for producing patterned structure and patterned ordering with lyotropic liquid crystalline polymer (LCP) film. Experimental results showed that the liquid crystalline ordering of lyotropic film could be controlled by shearing effects of the fluidic solvent though the patterned mold channels. In this work, two types of lyotropic LCPs were used to investigate the effects of the alkyl chain length of the lyotropic LCP on producing liquid crystalline ordering through the solvent-assisted fluidic patterning.

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Numerical Study on Performance of PEMFC with Block and Sub-channel of Cathode Flow Field (캐소드 유로에서 블록과 서브 채널의 고분자전해질 연료전지의 성능에 관한 전산해석 연구)

  • Jo, Seonghun;Kim, Junbom
    • Applied Chemistry for Engineering
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    • v.32 no.6
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    • pp.613-620
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    • 2021
  • A flow channel shape of PEMFC has an influence on the internal flow uniformity. If the reactant distribution in a flow path is not uniform during operation, both catalyst deactivation and mechanical damage of membrane could occur resulting in decreasing the membrane electrode assembly (MEA) durability. Numerous studies concerning flow design have been conducted to make smooth supply and uniform distribution of reactants in fuel cells. The baffle of flow path could improve fuel cell performance through the forced convection effect. A sub-channel, as an additional air flow path, could increase the reactant concentration and reduce the mass transfer loss via a smooth water discharge. In this study, computational fluid dynamics (CFD) was used to analyze the effect of blocks and sub-channels on the current density and oxygen concentration of the fuel cell. As a result, the limit current density and oxygen concentration at a rear block increased when using blocks and sub-channels in a flow channel. In particular, the current density increased significantly when the sub-channel was placed between two blocks. Also, the sub-channel position was optimized by analyzing the oxygen concentration, and the oxygen concentration was recovered at a rear block in the fuel cell.