• Title/Summary/Keyword: Spikes

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Optical imaging of epileptic activity and epilepsy treatments in neocortex

  • Suh, Min-Ah
    • Proceedings of the Optical Society of Korea Conference
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    • 2009.02a
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    • pp.427-428
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    • 2009
  • Optical imaging offers excellent spatio-temporal sensitivity that is unparalleled by any other perfusion based imaging techniques. We used in vivo optical recording of intrinsic signals (ORIS) to map neurovascular hemodynamics of perfusion, oximetry and membrane potential during epileptic events in rat and mouse neocortex. Studies of hemodynamic changes with ORIS alone were also performed in human. Laboratory studies in rodent epilepsy models have demonstrated a persistent increase in deoxygenated hemoglobin (Hbr) and a decrease in tissue oxygenation during interictal spikes and ictal events. This "epileptic dip", like the "initial dip" recorded during normal sensory processing, implies that the enormous rise in cerebral blood flow (CBF) is inadequate to meet the increased metabolic demands associated with synchronized epileptic activity. These findings are critically important to the interpretation of the perfusion-based imaging studies, such as fMRI. In addition, we visualized the effect of direct cortical electrical stimulation, an alterative epilepsy treatment. The optical data following direct cortical electrical stimulation showed that hemodynamic signals are sensitive to different electrical stimulation parameters. Furthermore, our recent data demonstrated that the application of unilateral electrical stimulation is able to elicit bilateral hemodynamic responses in rat neocortex.

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Trend of AI Neuromorphic Semiconductor Technology (인공지능 뉴로모픽 반도체 기술 동향)

  • Oh, K.I.;Kim, S.E.;Bae, Y.H.;Park, K.H.;Kwon, Y.S.
    • Electronics and Telecommunications Trends
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    • v.35 no.3
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    • pp.76-84
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    • 2020
  • Neuromorphic hardware refers to brain-inspired computers or components that model an artificial neural network comprising densely connected parallel neurons and synapses. The major element in the widespread deployment of neural networks in embedded devices are efficient architecture for neuromorphic hardware with regard to performance, power consumption, and chip area. Spiking neural networks (SiNNs) are brain-inspired in which the communication among neurons is modeled in the form of spikes. Owing to brainlike operating modes, SNNs can be power efficient. However, issues still exist with research and actual application of SNNs. In this issue, we focus on the technology development cases and market trends of two typical tracks, which are listed above, from the point of view of artificial intelligence neuromorphic circuits and subsequently describe their future development prospects.

Air-Sea Heat Flux Estimation by Ocean Data Assimilation Using Satellite and TOGA/TAO Buoy Data

  • Awaji, Toshiyuki;Ishikawa, Yoichi;Iida, Masatora;In, Teiji
    • Proceedings of the KSRS Conference
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    • 1999.11a
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    • pp.221-226
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    • 1999
  • A data assimilation system for a 1-dimensional mixed layer model has been constructed using the adjoint method. The classical adjoint method does not work well for the mixed layer variabilities due to the occurrence of spikes in the gradient of the cost function. To solve this problem, the two techniques of scaling the cost function and optimization in the frequency space are used. As a result, the heat flux can be reliably estimated with an accuracy of 8Wm$^{-2}$ rms error in the identical twin experiments. We then applied this system to the tropical Pacific TOGA-TAO buoy data. The air-sea heat flux as well as the mixed layer variability were estimated in close approximation to the buoy data, particularly on time scales longer than the seasonal one.

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A Selection Method of Optimal Digital Low-pass Differentiator for Spike Detection of Surface Motor Unit Action Potential (표면 운동단위 활동전위 스파이크 검출을 위한 최적의 디지털 저역통과 미분기 선정 방법)

  • Lee, Jin;Kim, Sung-Hwan
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.60 no.10
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    • pp.1951-1958
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    • 2011
  • The objective of this study is to analyze the performance of digital low-pass differentiators(LPD) and then to provide a method to select effective LPD filter, for detecting spikes of surface motor unit action potentials(MUAP). The successful spike detection of MUAPs is a first important step for EMG signal decomposition. The performances of simple and weighted LPD(SLPD and WLPD) filters are analyzed based on different filter lengths and varying MUAPs from simulated surface EMG signals. The SNR improving coefficient and effective MUAP duration range from the analysis results can be used to select proper LPD filters under the varying conditions of surface EMG.

Waveform Detection Algorithm based on the Search of Distinctive Line-Segments (검색에 기초한 파형 검출 알고리듬)

  • 박승훈;장태규
    • Journal of Biomedical Engineering Research
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    • v.14 no.3
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    • pp.265-272
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    • 1993
  • We present a new waveform detection method, based on the search of distinctive line-segments. The method is based on the basic assumption that the waveform morphology of biological signals is readily characterized by a sequence of the distinctive line-segments and their structural features. In this method, the distinctive line-segments are first searched for, and a structural feature analysis is performed an the distinctive line-segments found. Experiments of detecting epileptic spikes were carried out to evaluate the detection per formance of the method. Two subjects were used for training and tuning the algorithm and four subjects for testing the method. The results were obtained on two different performance indices, detection ratio and the number of false detections per minute.

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EEG WAVEFORM DETECTION BASED ON THE SEARCH OF DISTINCTIVE LINE-SEGMENTS (특징적인 직선요소들의 검색에 기초한 EEG 파형 검출)

  • Park, Seung-Hun;Chang, Tae-Kyu
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.05
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    • pp.121-122
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    • 1992
  • We present a new EEG waveform detection method, based on the search of distinctive line-segments. The method is based on the assumption that EEG waveform morphology is characterized by a sequence of its distinctive line-segments and their structural features. In this method, the distinctive line segments are first searched for, and the structural feature analysis is performed on the found line-segment sequence. Experiments of detecting epileptic spikes are performed on four different subjects.

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Single-Phase Z-Source AC-AC Converter (SZAC) with Buck/Boost In-Phase and Out-Of-Phase Operation

  • Khai, Nguyen Minh;Jung, Young-Gook;Lim, Young-Cheol
    • Proceedings of the KIPE Conference
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    • 2008.06a
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    • pp.376-378
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    • 2008
  • A new family of single-phase Z-source ac-ac converter(SZAC) based on single-phase matrix converter (SPMC) is proposed in this paper. Compared to conventional Z-source ac-ac converter, the proposed SZAC has unique feature: providing a wide range of output ac voltage with buck/boost in-phase (maintaining phase angle) and buck/boost out-of-phase (reversing phase angle) operation. A new commutation strategy is used to eliminate voltage spikes on switches. The operating principle of the proposed SZAC is presented. Analysis and experimental results are also presented.

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Single-Phase Z-Source Matrix Converter (SZMC) with Output Voltage Boost Capability

  • Nguyen, Minh-Khai;Jung, Young-Gook;Lim, Young-Cheol
    • Proceedings of the KIPE Conference
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    • 2008.06a
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    • pp.234-237
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    • 2008
  • This paper deals with a new single-phase Z-source matrix converter (SZMC) topology. Unlike other conventional configurations, the proposed SZMC is not only a step-up frequency converter but also a step-down frequency converter and a voltage boost capability. Thus, the proposed SZMC is also called a frequency step-up/down and voltage step-up converter. A safe-commutation strategy is used in SZMC as free-wheeling operation to eliminate voltage spikes on switches. The operating principles and experimental results of the proposed SZMC are presented.

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Power Factor with Single Power Stage AC/DC Converter Operated in Active-Clamp Mode (능동 클램프 모드로 동작하는 단일 전력 AC/DC 컨버터에 의한 역률개선)

  • Yoon, Shin-Yong;Baek, Hyun-Soo;Kim, Yong;Kim, Cherl-Jin;Eo, Chang-Jin
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.50 no.8
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    • pp.392-401
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    • 2001
  • This paper presents the single-stage high power factor AC to DC converter operated in active-clamp mode. The proposed converter is added active-clamping circuit to boost-flyback single-stage power factor corrected power supply. The active-clamping circuit limits voltage spikes, recycles the energy trapped in the leakage inductance, and provides a mechanism for achieving soft switching of the electronic switches to reduce the switching loss. The auxiliary switch of active-clamping circuit uses the same control and driver circuit as the main switch to reduce the additional cost and size. To verify the performance of the proposed converter, a 100W converter has been designed. The proposed converter gives good power factor correction, low line current harmonic distortions, and tight output voltage regulation, as used unity power factor.

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A Study on the DC Link Inductor and Clamping Capacitor in GTO Inverter (GTO 인버터에서의 직류 링크 인덕터 및 클램핑 커패시터의 특성 고찰)

  • Jeon, Young-Keon;Yoon, Yong-Ki;Lee, Gie-Tae;Kim, Jin-Pyo;Choi, Sang-Won;Lee, Jong-Ha
    • Proceedings of the KIEE Conference
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    • 1999.07f
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    • pp.2628-2631
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    • 1999
  • One of the limitations of conventional ASCI for high-power induction motor drives is the high voltage that is produced in the commutation capacitors during the current commutation from one phase to another. Since the capacitor voltage appears directly on the semiconductor components, it increases their required voltage ratings. Also, the high-voltage spikes generated at the motor terminals may cause damage to the motor insulation. And we investigated how de input power is increased or decreased according to size of de link inductor. In this paper, de link inductor and clamping capacitor in GTO inverter suitable for induction motor drives are propose through experiment.

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