• 제목/요약/키워드: Skin Test

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양말 소재별 인체생리적 반응 및 주관적 감각평가 (Evaluation of Physiological Responses and Subjective Sensation in Different Sock Materials)

  • 김칠순;정명희
    • 한국의류학회지
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    • 제25권8호
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    • pp.1475-1483
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    • 2001
  • The purpose of this study was to determine the physiological responses and subjective sensation according to fiber content of socks. Six female students participated in the wear trial test which was conducted in controled environmental chamber with 26${\pm}$1$^{\circ}C$ and 60${\times}$3%. R.H.SAS program was used for statistical analysis. The results of this study were as follows. Mean skin temperature was significantly different among three different socks. AWNP socks had the highest mean skin temperature and instep temperature. Also relative humidity in the microclimate of socks as well as heart rate were influenced by fiber content of socks, However, test of subjective sensation such as thermal, humid, comfort sensation showed that there was no significant difference among three different socks thermal sensation during the exercise and recovery period.

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CORRELATION BETWEEN SPF INDEX AND SAFETY MARKER IN SUNCREENS

  • Kim, Jong-Won;Suh, Soo-Kyung;Park, Ju-Young;Park, Chang-Won;Seo, Kyung-Won;Kim, Kyu-Bong;Kim, Kwang-Jin;Kim, Jae-Hee;Lee, Sun-Hee
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.195-195
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    • 2002
  • In recent years, the safety of sunscreens has been challenged based on the reports of its adverse effect on users; dermatitis, allergic contact dermatitis, photoallergic contact dermatitis. To investigate a correlation between sun protection factor (SPF) and the safety of sunscreens, we measured in vitro SPF index using homosalate as a standard and examined the toxicity tests on cosmetics; primary skin irritation tests, ocular irritation test, and skin sensitization test.(omitted)

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Neurological aspects of anhidrosis: differential diagnoses and diagnostic tools

  • Park, Kee Hong;Park, Ki-Jong
    • Annals of Clinical Neurophysiology
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    • 제21권1호
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    • pp.1-6
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    • 2019
  • Anhidrosis refers to the condition in which the body does not respond appropriately to thermal stimuli by sweating. Sweating plays an important role in maintaining the body temperature, and its absence should not be overlooked since an elevated body temperature can cause various symptoms, even leading to death when uncontrolled. The various neurological disorders that can induce anhidrosis make a detailed neurological evaluation essential. The medication history of the patient should also be checked because anhidrosis can be caused by various drugs. The tests available for evaluating sweating include the quantitative sudomotor axon reflex sweat test, thermoregulatory sweat test, sympathetic skin response, and electrochemical skin conductance. Pathological findings can also be checked directly in a skin biopsy. This review discusses the differential diagnosis and evaluation of anhidrosis.

Training Program to Raise Consciousness Among Adolescents for Protection Against Skin Cancer through Performance of Skin Self Examination

  • Balyaci, Ozum Erkin;Kostu, Nazan;Temel, Ayla Bayik
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권10호
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    • pp.5011-5017
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    • 2012
  • Background: Overexposure to sunlight in childhood and the adolescent period and associsated sunburns significantly increase the risk of skin cancer in adulthood. In Turkey, the incidence of skin cancer in the general population is 0.8%. The incidence is 0.6% and the mortality rate is 0.4% for men, while these rates are 1.0% and 0.7%, respectively, for women. If skin cancer is found early, its treatment is facilitated. Therefore, personal skin examination is important for early diagnosis. Objectives: Our aim was to determine the effects of training for raising consciousness among adolescents to protect against skin cancer by influencing skin self examination behavior. Method: This quasi experimental intervention study was conducted between February and April 2012 in Izmir. The study population consisted of students attending $6^{th}$, $7^{th}$ and $8^{th}$ classes of a primary school (n:302). No sampling was performed. Data were collected with a form developed by the researchers based on the literature. The first part of form is aimed to determine demographic characteristics of adolescents (3 questions) and their risk status of skin cancer (6 questions). The second part was prepared for skin cancer risks of adolescents (8 questions) and indications of skin cancer (12 questions). The last part was intended to determine their knowledge about skin self examination (4 questions) and behavioral stages of skin self examination (1 question). Data collection was achieved with a questionnaire form in three phases. In the 1st phase, data about demographic characteristics of students, risk status of skin cancer, knowledge level of skin cancer and behavior stages were collected. In the $2^{nd}$ phase, skin self examination training based on the transtheoretical model was performed within the same day just after obtaining preliminary data. In the $3^{rd}$ phase, adolescents were followed up three times to establish the efficacy of the training (on the $15^{th}$ day after training program and at end of the $1^{st}$ and $2^{nd}$ months). Follow-up data were evaluated by questioning skin self examination performing behavior stages through electronic mail. Results: Half of the adolescents (50.5%) are male, and 58.4% of them are 13 years old with a mean age of $12{\pm}1.15$ years. About 29.4% of adolescents had brown hair color, 37.9% had brown/hazel eye color, 29.4% had white skin, and 47.2% had fewer than 10 moles in their body. The pretest mean score on knowledge level about risks of skin cancer was found to be $4.19{\pm}1.96$, while the post-test mean score was $6.79{\pm}1.67$ (min:0, max:8).The pretest mean score about indications of skin cancer was $7.45{\pm}3.76$, while the post-test mean score was $10.7{\pm}2.60$ (min:0, max:12). The increases were statistically significant (p<0.05). The behavior "I do not perform skin self examination regularly in every month and I do not think to perform it in the next 6 months" was reduced from 52.8 to 35.5% after training. Conclusion: The training program organized to raise consciousness among adolescents for protection against skin cancer increased the knowledge level about risks and indications of skin cancer and it also improved the behavior of performing skin self examination.

SIP말뚝의 주면마찰특성 및 비선형 수치모델식 산정에 관한 연구 (A Study on the skin friction characteristics of SIP and the estimation of the nonlinear numerical modelling equation)

  • 천병식;임해식;김도형
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2003년도 봄 학술발표회 논문집
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    • pp.153-160
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    • 2003
  • While the interests on the environmental problem during the construction are increasing, the use of low noise-vibration auger-drilled pilling is increasing to solve noise and vibration problem in pilling. Therefore, in Korea, SIP(Soil-Cement Injected Precast Pile) method is mainly used as auger-drilled pilling. However, there is no proper design criteria compatible with the ground condition of Korea, so which is most wanted. To improve and supplement this situation, direct shear tests between SIP pile skin interface and soil were executed on various conditions. Through the analysis of test results, skin resistance characteristics of SIP were investigated thoroughly. Also, the nonlinear unit skin resistance capacity model with SM, SC soil were suggested.

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S-자형 플랩을 이용한 충격파와 경계층 간섭현상 제어에 관한 연구 (Control of Shock Wave/Boundary-Layer Interactions Using S-Shaped Mesoflaps)

  • 이열
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2002년도 학술대회지
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    • pp.159-160
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    • 2002
  • New S-shaped aeroelastic mesoflaps are utilized to control normal shock/boundary-layer interactions. New generation of the mesoflaps is designed f3r a better rigidness and a good flow uniformity across the ulteractions. ,Major advantages of the mesoflap system can be a better total pressure recovery downstream of the interactions due to the lambda shock structure over the flap system, and a rehabilitation of the thickened boundary layer due to bleeding through a cavity underneath the flap system. Skin friction has been measured downstream of the interactions, using the laser interferometer skin friction (LISF) meter, which optically detects the rate of thinning of an oil film applied to the test surface. Various flap-thicknesses of the S-shaped mesoflap arrays are tested, and the results are compared to the solid-wall reference case. Overall, not much difference in the level of skin friction is noticed for the S-shaped flap arrays of various thicknesses, and its level is lower than the skin friction downstream of the solid-wall interaction

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HRV 검사를 통한 피부과 내원환자의 자율신경 균형 및 스트레스 단면 연구 (The Cross Sectional Study of Autonomic Nerve Balance And Stress In Patient Who Visted Dept. of Oriental Medical Dermatology)

  • 김규석;남혜정
    • 한방안이비인후피부과학회지
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    • 제21권2호
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    • pp.142-153
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    • 2008
  • Objective : Etiologically, stress is a important factor to immune system and skin disease. Human body is controled to keep his homeostasis from stress by autonomic nerve system. So we investigated autonomic nerve balance and stress level of patients with skin disease by heart rate variability(HRV) test. Research Methods and Procedures : Fifty two patient(from 15 years old to 35 years old) who visited Dept. of Oriental medical Dermatology, Kyunghee university at first and had an examination by HRV test, were selected as the subject of our study. We checked items of HRV test(such as SDNN, RMSSD, VLF, LF, HF, TP, norm-LF, norm-HF, LF/HF ratio, LnHF and LnHF), and analyzed time and frequency domain by sex, age, onset, color on end of patient's tongue, sweating and sleep condition. Results and Conclusion : Men showed significant higher SDNN, RMSSD, LF, norm-LF, norm-HF, LF/HF ratio, LnLF and LnHF than women(p <0.05). Patients who were attacked by skin disease within 6 months, showed significant higher TP and VLF than over 6 months(p <0.05). Patients with normal color on the end of their tongue showed significant higher TP and VLF than with flare color. We analyzed correlation to color on the end of tongue and RMSSD. Prevalence risk(RMSSD <20ms) in the case of normal color on the end of tongue was 5 times as high as in the case of flare color(p <0.1). And we analyzed correlation to age and LF/HF ratio. Prevalence risk(LF/HF ratio <1) of patients from 15 years old to 25 years old was 1.467 times as high as from 26 years old to 35 years old(p <0.1).

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실내환경 주요 호흡기 알레르기 항원 감작검사를 위한 피부단자 시험과 혈청 ELISA시험의 상관성에 대한 연구 (Correlation Between Skin Prick Test and Enzyme-linked Immunosorbent Assay Using Serum for Identification of Subjects Positive to Major Indoor Respiratory Allergens)

  • 허용;김형아
    • 한국환경보건학회지
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    • 제34권5호
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    • pp.369-373
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    • 2008
  • The indoor environment is an important source of exposure to various aeroallergens and pathogenic microorganism. It has been shown that exposure to aeroallergens enhances the risk of indoor inhabitants developing asthma. Since the skin prick test, a typical clinical method for identification of subjects positive to allergens, can rarely cause fatal or non-fatal reactions in susceptible persons, an in vitro assay such as ELISA using serum has been considered for testing positivity against various allergens. We evaluated the validity of a serum ELISA kit for screening positive subjects to major aeroallergens including Dermatophagoides farinae, Dermatophagoides pteronyssinus, cockroach, Alternaria, Cladosporium, Aspergillus, Penicillium, dog hair, cat fur, mugwort, and ragweed. The ELISA results were compared with the skin prick test results, and sensitivity, specificity, and overall accuracy were calculated to each allergen. Higher sensitivities were obtained from D. farinae, (77.8%) and D. pteronyssinus (69.2%), but sensitivities to Aspergillus, Penicillium, dog hair, cat fur, and ragweed were very low down to 0%. Specificity ranged from 88.7% (cat fur) to 100% (mugwort and ragweed). Overall the accuracy of the serum ELISA kit was relatively high, in that the lowest was 85.1% for cat fur and the highest was 98.6% for Alternaria, Cladosporium, and ragweed. Considering specificity and overall accuracy for the serum ELISA kit, it may be considered reliable. However, when the kit is used for screening purpose, positivity to aeroallergens should be carefully determined since sensitivity for the kit is low.

4-Chloro-m-cresol, Didecyl Dimethyl Ammonium Chloride 그리고 Glutaraldehyde로 구성된 살균 소독제에 대한 피부 자극성 및 감작성 시험에 관한 연구 (Skin Irritation and Sensitization Studies on a Disinfectant Composed of 4-Chloro-m-cresol, Didecyl Dimethyl Ammonium Chloride, and Glutaraldehyde for the Bactericide)

  • 정희식;김석;천명선;정원철;김동혁;임정주;손호영;김무석;김곤섭;이후장
    • 한국식품위생안전성학회지
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    • 제22권2호
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    • pp.110-115
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    • 2007
  • 살균소독제, 크레오콤플렉스 (4-chloro-m-cresol(10%), didecyldimethyl ammonium chloride(10%), glutaraldehyde (10%))에 대하여 토끼와 기니픽을 이용하여 피부 자극성 및 감작성 평가를 각각 수행하였다. 토끼의 등 부위의 털을 제거하고 찰과부위와 비찰과 부위에 여러 농도로 크레오콤플렉스를 도포한 후, 피부 자극성을 확인한 결과 10% 크레오콤플렉스의 1차 자극지수가 0.13으로 비자극성 물질로 분류되었다. 기니픽을 이용한 피부 감작성 시험에서는 1, 2차 감작 후, 2주 후 10% 크레오콤플렉스로 감작을 유도한 결과, 어떠한 알러지 반응도 보이지 않아, 감작성이 매우 약한 물질로 분류되었다. 따라서, 본 연구를 통하여, 10% 크레오콤플렉스는 피부자극성과 감작성을 야기하지 않는 물질로 평가되었다.

화장품원료를 위한 오존화 올리브오일의 동물 피부자극 측정에 관한 연구 (A Study on Animal Skin Irritation Measurement of Ozoneized Olive Oil for Cosmetic Ingredients)

  • 김덕술
    • 융합신호처리학회논문지
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    • 제22권1호
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    • pp.14-19
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    • 2021
  • 본 연구는 오존화 올리브오일이 피부 질환에 우수한 치료효과를 가진다는 연구 결과가 알려지면서 오존을 피부 질환치료에 사용하려는 다양한 시도가 있어 왔지만, 적절한 계측 절차가 수립되지 않아 국내에서는 임상적으로 가치가 있는 양질의 데이터를 확보할 수 없었다. 일반적으로 화장품의 성능확인을 위한 목적으로 동물실험을 통해 실측 데이터 계측을 진행하는 경우는 많지 않지 않으나, 독성실험의 경우 피부의 반응을 정확히 계측하는 것이 반드시 필요한 사항으로 권고되고 있어 본 실험이 실시되었다. 본 실험에서는 실험 Rabbit에 대한 오존화오일(고농도)에 대한 피부자극 평가를 위하여 오존화오일(고농도)을 털을 제거하여 피부가 노출된 Rabbit의 등 부위에 도포한 후 24시간 동안 영상처리장치와 육안 검사를 통해 피부 반응을 관찰하여 피부자극 평가를 위한 데이터를 확보하고자 하였고 오존화오일(고농도)의 의한 일반적인 반응, 사망과 같은 반응을 함께 측정하는 과정을 진행하였다. 총 24시간 이내의 결과에서 실험에 사용된 동물들 모두에서 시험물질 처치 부위의 육안관찰, 영상촬영을 통한 이상 반응은 관찰되지 않았고 사망과 같은 돌발적인 이상반응 역시 확인되지 않아 오존화오일(고농도)의 생체 안전성을 확인할 수 있었다.