• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권1호
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• pp.7-18
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• 2021

Purpose: The long-term efficacy and safety of infliximab (IFX) in children with ulcerative colitis (UC) have not been well-evaluated. Here, we reviewed the long-term durability and safety of IFX in our single center pediatric cohort with UC. Methods: This retrospective study included 20 children with UC who were administered IFX. Results: For induction, 5 mg/kg IFX was administered at weeks 0, 2, and 6, followed by every 8 weeks for maintenance. The dose and interval of IFX were adjusted depending on clinical decisions. Corticosteroid (CS)-free remission without dose escalation (DE) occurred in 30% and 25% of patients at weeks 30 and 54, respectively. Patients who achieved CS-free remission without DE at week 30 sustained long-term IFX treatment without colectomy. However, one-third of the patients discontinued IFX treatment because of a primary nonresponse, and one-third experienced secondary loss of response (sLOR). IFX durability was higher in patients administered IFX plus azathioprine for >6 months. Four of five patients with very early onset UC had a primary nonresponse. Infusion reactions (IRs) occurred in 10 patients, resulting in discontinuation of IFX in four of these patients. No severe opportunistic infections occurred, except in one patient who developed acute focal bacterial nephritis. Three patients developed psoriasis-like lesions. Conclusion: IFX is relatively safe and effective for children with UC. Clinical remission at week 30 was associated with long-term durability of colectomy-free IFX treatment. However, approximately two-thirds of the patients were unable to continue IFX therapy because of primary nonresponse, sLOR, IRs, and other side effects.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권4호
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• pp.357-365
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• 2021

Purpose: A change in diagnosis from ulcerative colitis (UC) to Crohn's disease (CD) has been reported in pediatric inflammatory bowel disease; however, only a few clinical characteristics and predictors of this diagnostic change have been reported. We aimed to describe the clinical characteristics of patients with UC who underwent a change in diagnosis to CD and identify variables associated with the change. Methods: The medical records of pediatric patients with UC who were followed up at the National Center for Child Health and Development between 2006 and 2019 were retrospectively reviewed. Clinical data on disease phenotype, laboratory parameters, endoscopic findings, and treatment of patients whose diagnosis changed to CD (cCD) were compared to those of patients whose diagnosis remained UC (rUC). Results: Among the 111 patients initially diagnosed with UC, 11 (9.9%) patients were subsequently diagnosed with CD during follow-up. There was no significant difference between the cCD and rUC groups in terms of sex, age at initial diagnosis, and the extent and severity of disease at initial diagnosis. Albumin and hemoglobin levels were significantly lower in the cCD group than in the rUC group. The proportion of patients who required biologics was significantly higher in the cCD group than in the rUC group (p<0.05). Conclusion: Approximately 10% children initially diagnosed with UC were subsequently diagnosed with CD. Hypoalbuminemia and anemia at initial diagnosis and use of biologics could be predictors of this diagnostic change.

• 가족자원경영과 정책
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• 제26권2호
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• pp.53-70
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• 2022

이 연구는 다양한 가정의 건강성 증진 이라는 건강가정정책 및 제 4차 건강가정기본계획의 강조점에 주목하여 한부모가족의 건강성 지표를 개발하여 제시하고자 한다. 이 지표를 통해 현장의 한부모가족 사업 효율화 및 활성화에 기여하고자 한다. 본 연구가 개발한 한부모가족 건강성 지표는 특히 현장을 방문한 가족이 건강성 지표를 측정하여 강점과 취약점을 발견할 수 있고 이에 근거하여 컨설팅과 사례관리, 교육/상담/자조모임 등 프로그램과의 연계 등으로 이어질 수 있다는 점에서, 다양한 가족에 대한 맞춤형의 사업을 수행할 수 있는 기반이 될 것이다. 한부모가족 건강성 지표를 개발하기 위한 연구방법과 절차로는 먼저, 선행연구를 통해 가정의 건강성, 한부모가족의 실태와 요구를 파악하여 한부모가족 건강성 지표의 영역을 검토하였다. 예비조사를 통해 건강성 지표 초안을 마련하였고, 본조사의 결과를 통계분석하여 지표의 타당성과 신뢰도를 검증하였다. 이러한 과정을 통해 최종적으로 5개 영역(기본적 토대, 부모역할, 일-생활 균형, 사회적 네트워크, 라이프스타일, 가정경영과 생애설계)5개 영역, 총 48개 항목으로 구성된 한부모가족 건강성 지표를 확정하였다. 이 연구가 개발하여 제시한 한부모가족 건강성 지표는 생활과학이나 가정관리학, 가정복지학 등의 고유한 관점을 반영하였다는 점에서 그 의의를 찾을 수 있다. 가정의 건강성은 생활과학, 가정관리학, 가정복지학 등에서 지속적으로 연구해 온 주제이다. 따라서 건강가정지원센터, 가족센터와 같은 현장에서 사업을 할 때 건강성 지표를 활용함으로써 다른 기관 사업과의 차별화를 모색할 수 있다. 나아가 맞벌이가정, 다문화가족, 조손가족, 분거가족 등 다양한 형태의 가정에게 적용할 수 있는 건강성 지표 개발의 선행 자료로서의 유용성도 함께 강조할 수 있을 것이다.

• 가족자원경영과 정책
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• 제26권4호
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• pp.25-38
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• 2022

이 연구는 취업 청년 1인가구의 일상적인 돌봄노동 경험을 분석하고자 하였다. 1인가구의 증가와 함께 다양한 학문분야에서, 다양한 주제로 1인가구 연구를 축적하고 있다. 가족자원경영학 분야는 오랫동안 가사노동, 돌봄노동을 연구해 온 바, 이 연구는 1인가구의 일상적인 돌봄노동 경험을 사례연구를 통해 분석함으로써, 가족자원경영학에서 1인가구 연구의 활성화에 기여하고자 하였다. 2022년 8월, 취업한 상태의 청년 1인가구 10명을 대상으로 심층면접을 실시하였다. 이를 통해 날마다 수행하는 돌봄노동의 특성, 돌봄노동 수행의 경험을 밝히고자 하였다. 연구주제는 첫째, 1인가구로서의 특성과 관련된 내용이다. 1인가구로 살게 된 동기와 자발성, 1인가구로 산 기간, 만족도 등을 조사하였다. 둘째, 일상적인 돌봄노동 수행실태를 분석하였다. 셋째, 돌봄노동을 수행하면서 갖게 된 경험에 주목하여 새로운 발견, 돌봄노동의 의미에 대한 해석 등을 분석하였다. 분석 결과, 연구참여자들은 1인가구로 살면서 혼자 수행하는 돌봄노동을 통해 돌봄노동이 독립을 위한 필수조건이라는 사실을 새롭게 깨닫게 되면서 주체성, 자부심, 책임감 등을 갖게 되었다는 점을 발견하였다. 또한 돌봄노동을 통해 일상생활의 여러 측면에서 변화의 경험이 함께 발견되었다. 연구결과에 기초하여 향후 가족자원경영학 분야에서 1인가구를 주제로 한 후속연구에의 제안점을 도출하였다.

• 한국가정과학회지
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• 제10권1호
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• pp.19-25
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• 2007

The study is attempted to help double-income families use resources efficiently and rationally by analyzing The Time Use each of working women and housewives having preschool children based on the data of The Time Use survey carried out in 2004 and promote understandings on their quality of life, lifestyle and family welfare. To this end, the study analyzes the actual The Time Use of double-income families haying preschool children. The findings of the study are as follows: First, according to the comparison of The Time Use between double-income families and single-income families in 1999 and 2004, there is no significant difference in husbands' participation time in family management or family care between 1999 and 2004. Second, according to the comparison of The Time Use between double-income families and single-income families depending on the presence or non-presence of preschool children, families haying preschool children spent much more hours in family care than families without preschool children. Third, according to the comparison of the weekend schedule between double-income families and single-income families, it is found that working women work much more than housewives not only on weekdays but also on weekends and in particular, it is found that working women having preschool children work 2 hours longer than housewives.

• 대한물리치료과학회지
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• 제15권2호
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• pp.79-86
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• 2008

Background: The purpose of this study was to present a practical method of medical treatment to improve the balance and motor ability of the mentally retarded child with a single mentally retarded child-subject. Methods: The subject of the study was a 39-month-old mentally retarded female. This study included a 2-week basic period and a 13-week treatment period. The treatment method was based on the Bobath Approach. Gross motor function measurement (GMFM) was used to examine changes in motor ability, and the Pediatric Balance Scale (PBS) was used to measure changes in balance ability. The curative program was composed of normalization of muscle tone, strengthening of leg endurance and muscular strength, the improvement of trunk alignment, and the increase of balance. Visual rate of change was used to examine the results. Results: As a result of this study, balance ability increased on the Pediatric Balance Scale (PBS) by 24 points, and motor function increased in terms of Gross Motor Function Measurement (GMFM) by 6.9% (18 points). Standing increased by 41% (16 points), and walking, running, and jumping increased by 31.9% (23 points) compared to thebasic period. Therefore, the Bobath Approach appears to be an appropriate method to improve balance and motor ability in mentally retarded children. Conclusion: It is surmised that aggressive intervention by physical therapists and occupational therapists, and a follow-up study, are required for the growth of motor ability in mentally retarded children.

• 한국간호교육학회지
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• 제19권4호
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• pp.508-517
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• 2013

Purpose: The purpose of this study was to evaluate the effectiveness of infant CPR (Cardiopulmonary Resuscitation) immediate remediation[LAB2]. Methods: This is a quasi-experimental study with a non-equivalent comparison group pre-post test design. Participants were 73 child care teachers in J district in Seoul. The experimental group (35) received immediate remediation with video learning [LAB3]for infant CPR education and the control group (38) received video learning only. We investigated confidence of infant CPR and tested single-rescuer infant CPR performance depending on a checklist (8 items). Data were collected before and right after to evaluate the confidence of infant CPR and before, right after and 2 weeks after the education to evaluate the skill performance and final acceptance. Results: There was a significant increase in confidence of infant CPR in the experimental group and control group. There was a statistically significant difference in the degree of skill performance between groups according to the amount time (F=10.58, p<.001). The degree of skill performance was tested two weeks after the education and immediate remediation was 5.35 times more effective compared to the video image demonstration (B=1.677, p<.001). Conclusion: The findings provide the necessity of immediate remediation education of infant CPR to increase confidence and skill performance ability.

• Parasites, Hosts and Diseases
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• 제52권6호
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• pp.677-680
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• 2014

Infection cases of diphyllobothriid tapeworms are not much in the below teen-age group. We report a case of Diphyllobothrium nihonkaiense infection in a 13-year-old boy. He presented with severe fatigue, occasional abdominal pain at night time. He also had several episodes of tapeworm segment discharge in his stools. By his past history, he had frequently eaten raw fish including salmon and trout with his families. Numerous eggs of diphyllobothriid tapeworm were detected in the fecal examination. We introduced amidotrizoic acid as a cathartic agent through nasogastroduodenal tube and let nearly whole length (4.75 m) of D. nihonkaiense be excreted through his anus. After a single dose of praziquantel, the child's stool showed no further eggs, and his symptoms disappeared. The evacuated worm was identified as D. nihonkaiense by mitochondrial cox1 gene analysis. Here we report a successful extracorporeal worm extraction from an infection case of D. nihonkaiense by the injection of amidotrizoic acid.

• 가정과삶의질연구
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• 제30권3호
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• pp.59-67
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• 2012

This study investigate the influence of resilience on organizational commitment using social support as a mediating variable for kindergarten and childcare teathers. The subjects were 630 kindergarten and childcare teathers. The collected data were analyzed by Pearson's correlation as well as single and multiple regressions that used SPSS Win 19.0. The results were as follows: (1) The resilience was significantly associated with organizational commitment of kindergarten and childcare teachers. (2) The resilience was significantly associated with social support of kindergarten and childcare teachers. (3) The resilience was not significantly associated with organizational commitment of kindergarten and childcare teachers, controlled by social support. The results showed the social support was more important variable affecting organizational commitment of kindergarten and childcare teachers than the resilience. As a result, teachers have to be strengthened for support of social emotion that helps to control of their emotional condition and social evaluation that estimates their role positive under administration system.

• 부모자녀건강학회지
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• 제20권1호
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• pp.10-17
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• 2017

Purpose: This study was conducted to investigate the effects of simulation-based education using high-fidelity simulator and standardized patient in nursing care for children with fever on nursing students. Methods: A total of 166 senior nursing students who completed pediatric nursing practicum courses participated in this study. The single group study design with pretest and posttest was used. The simulation education was provided for 200mins including orientation, simulation preparation, simulation practicum, and debriefing. Pre and post surveys were performed using questionnaires on clinical performance competency, communication skills, critical thinking disposition and self-confidence. Results: The mean scores of clinical performance competency (t=-2.56, p<.05), communication skills (t=-6.39, p<.001), critical thinking disposition (t=-3.43, p<.001), and self-confidence (t=-3.72, p<.001) in posttest were significantly higher than those in pretest. Also, clinical performance competency in nursing care for children with fever has significant relationships with communication skills, critical thinking disposition and self-confidence. Conclusion: The results indicate that simulation-based education using high-fidelity simulator and standardized patient is an effective strategy for improving clinical performance competency, communication skills, critical thinking disposition and self-confidence in nursing students. Further study is needed to verify the effects.