• The Korean Journal of Legal Medicine
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• 제41권2호
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• pp.41-45
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• 2017

Fetal DNA (fDNA) detection in maternal serum is a challenge due to low copy number and the smaller size of fDNA fragments compared to DNA fragments derived from the mother. Massively parallel sequencing (MPS) is a useful technique for fetal genetic analysis that is able to detect and quantify small amounts of DNA. In this study, seven clinical samples of maternal serum potentially containing fDNA were analyzed with a commercial single nucleotide polymorphism (SNP) panel, the HID-Ion $AmpliSeq^{TM}$ Identity Panel, and the results were compared to those from previous studies. Reference profiles for mothers and fetuses were not available, but multiple Y chromosomal SNPs were detected in two samples, indicating that fDNA was present in the serum and thereby validating observations of autosomal SNPs. This suggests that SNP-based MPS can be valuable for fDNA detection, thereby offering an insight into fetal genetic status. This technology could also be used to detect small amounts of DNA in mixed DNA samples for forensic applications.

• Archives of Pharmacal Research
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• 제22권1호
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• pp.44-47
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• 1999

Three 1,2-benzothiazine derivatives were synthesized, and their analgesic / anti-inflammatory efficacy and their effect s of gastric irritation were evaluated. Among the three compounds, 39 exhibited the most potent anlagesic action, but the effect was weaker than that of piroxicam. Nonetheless, the compound showed 4 times more potent analgesic action with less gastric damage than did ibuprofen. These compounds did not show anti-inflammatory effect at an oral dose of 5 mg/kg.

• 한국의류학회지
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• 제11권1호
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• pp.29-42
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• 1987

This study was an attempt to survey, the relationships between women's values and preference in clothing design. For the measurement of values scale was to relect the theoretical, economic aesthetic, social. political and religious values explained by Allport-vernon- Lindzey. The preference rate in clothing design consisted of 50 items and 3 factors including color, form and texture. The questionnaire were administered to a sample of women (between college students and adult) who lined in Seoul, Korea. The date for 910 respondents were analyzed by person's carrelation coefficient, to-test and $x^2$ test. Through this study, the followings were founds; 1. Aesthetic value was the mast important of female college students values and economic value was the most important of adult's values. 2. There were significant relation between values and the preference for clothing form in line and style; 1) In line preference, adult women indicated negative correlation with religious values but positive correlation with aesthetic and political values. 2) In style preference, adult women indicated negative correlation with economic values positive correlation with social values, for female college students indicated positive correlation with aesthetic social and political values. 3. There were significant relation between values and preference for texture in touch, thickness, weight, light and luster; 1) In relationship between texture and values, adult women indicated touchness preference negative correlation with theoretical and religious values, for female college students indicated positive correlation with aesthetic and social values. 2) In thickness preference adult women indicated negative correlation with theoretical values but female college students indicated positive correlation with political values. 3) In weight preference, adult women indicated negative correlation with theoretical values. But female college students indicated positive correlation with religious values. 4) In brightness preference, only adult women indicated positive correlation with social values, negative correlation with economic values. In transparency preference, adult women indicated positive correlation with aesthetic values, negative correlation with religious values. 4. There were significant correlation among color and economic, aesthetic; political and religious values, that is, evacuation and economic political values in adult women there were positive correlation with religious values in female students. 1) In chroma only adult women indicated negative correlation with religious values. In warm and cold, positive correlation with economic values in both of them. 2) In coloration, adult women like a complement color indicated negative correlation with aesthetic values, but positive correlation with political values. 5. There were significant differences in the preference of clothing design between female college students and adult women; correlationship with color variables. Evacuation, both of them indicated negative correlation with chroma positive correlation with warm and cold and coloration. In chroma, adult women indicated negative correlation with coloration and warm and cold, for female students indicated negative correlation with coloration. 6. Comparison with clothing preference: 1) In color preference, adult women liked the most white, brown, blue and black in sequence. Female college students liked the most white, also the next is blue and pink. 2) Clothing design preference, there was significant difference in warm and cold and coloration, adult women more liked than female students. In shape of clothing, both of them indicated significant difference in line and style, female students more liked sporty style. In texture, adult women more liked soft thin light weight and bright. 3) In silhouette preference, the most is H-line, female college students more liked.

• 한국농촌간호학회지
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• 제17권2호
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• pp.59-66
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• 2022

Purpose: This study was conducted to provide basic data for college students living in the Seoul metropolitan area to prevent the spread of infectious diseases and explore countermeasures by identifying the degree of difference with anxiety, stress, and preventive health behavior before and after the COVID-19 vaccination. Methods: Data were collected from the subjects of the study, 192 college students aged 19 to 29 who completed the COVID-19 vaccination in the Seoul metropolitan area. The data were analyzed with the correlation, paired t-test, and independent t-test using the SPSS 27.0. Results: Preventive health behavior, health anxiety, and stress showed the positive correlation before and after the COVID-19 vaccination among the college students. After the COVID-19 vaccination, COVID-19 related stress including fear of infection (d=-0.11±0.09), and difficulty in social distancing (d=-0.21±0.08), and health behavior (d=-0.06±0.44) decreased compared to before the vaccination. Conclusion: Health education and health policies are required to continue preventive health behavior even after the vaccination.

• 대한간호
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• 제37권4호
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• pp.72-84
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• 1998

This study has been done for the purpose of testing the effects of education for women's health on the performance of health promoting behavior and self esteem of college women. The study was designed as simulated control group pretest-posttest design, the experimental group was composed 182 college women and the control group was composed 151 college women at D University in Seoul. The instruments used for this study were Health Promoting Behavior Scale developed by Walker et al(1987)were modified by Shin(1997) and Self Esteem Scale developed by Rosenberg(1965). The data were analyzed by chi-square test, t-test and ANCOVA using $SPSSIPC^+$ program. The results were as follows: 1. The result of the homogeneity test in terms of the demographic characteristics of two group showed that there were significant difference in major discipline($x^2=155.854$, p=.000), religion($x^2=6.325$, p=.011), and disease experience($x^2=3.949$, p=.046). 2. Hypotheses 1 that the college women who get women's health education will have a higher score of health promoting behavior than the college women who do not get women's health education was supported. The score of health promoting behavior between two group showed statistically difference(t=7.25, p= .000). Mer control of covariates(major discipline, religion, and disease experience), the score of health promoting behavior between two group showed statistically difference(F=31.817, p= .000). 3. Hypotheses 2 that the college women who get women's health education will have a higher score of self esteem than the college women who do not get women's health education was supported. The score of self esteem between two group showed statistically difference(t=4.91, p= .000). After control of covariates(major discipline, religion, disease experience), the score of self esteem between two group showed statistically difference(F=12.688, p= .000). The following suggestions are made based on the above results : 1) Replication of the research is needed to confirm effects of health education including the college man and various demographic differences. 2) More effective health education programs appropriate to subject need to be developed. 3) Nursing college or departments of nursing should make an effort to develop and carry out various health education program for health for all.

• 여성건강간호학회지
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• 제11권2호
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• pp.156-162
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• 2005

Purpose: The study was done to identify the relationship of symptoms of stress, cancer prevention behavior, the quality of life in women, and the factors influencing the quality of life. Method: The subjects of this study were 210 married women. They were living in Gyeonggi Province and Busan Metropolitan City. Symptoms of stress were measured by the Park's Stress Scale. Cancer preventive behavior was measured by Suh's Korean scale, and Smith Kline Beecham Quality of life' Scale by Dunbar. Data was analyzed with the SPSS program by ANOVA, Pearson's correlation, and Multiple Regression Analysis. Result: The higher scores of physical stress correlated with lower practice scores of cancer prevention behavior. Psychological and physical stress revealed negative correlations among sub-items of the QOL such as competence, psychological well-being, stability, physical well-being and activity. Multiple regression analysis revealed that the predictor of quality of life in the women was stress. A combination of symptoms of stress and cancer prevention behaviors accounted for 35.3% of the variance in the quality of life in the women. Conclusion: The most important factor influencing the quality of life of women was stress. Thus the study's findings can be useful in directing a comprehensive nursing care plan to improve the QOL of women.

• 약학회지
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• 제55권2호
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• pp.160-167
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• 2011

Cirsium japonicum var. ussuriense (CJ) is used as a folk medicine for diuretic, arthritis, dyspepsia, and bleeding in Korea. Until now, more than fifteen kinds of CJ were identified and among them, Cirsium japonicum var. nakaianum Nakai was selected as experimental material. Both that from The Medical Herb Garden of Seoul National University located at Gayang-dong, Koyang city and native that from a hillock near Dangjin, Chungnam were collected and analyzed to determine whether it is varied in efficacy on their habitats. Extracts and fractions of CJ had a strong effect of antibacterial activity on H. pylori and antioxidant effects. And the CJ from Garden and Dangjin were showed to be more efficient in acute gastritis through the HCl${\cdot}$ethanol-induced gastric lesion test and chronic gastritis through the indomethacin-induced gastric lesion test, respectively. This study proved that the effects of CJ are varied by their habitats. Also, these results suggest that the CJ has potentials for use as functional food and medicine.

• Journal of Nutrition and Health
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• 제35권9호
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• pp.962-969
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• 2002

This study examined the effect of calcium supplementation and exercise on bone mineral density (BMD) and general characteristics, dietary intake and biochemical measurements for 45 healthy middle-aged women (40-57 years). Subjects were divided in to 4 groups; control group (G1), exercise group (G2), calcium supplementation group (G3), and calcium supplementation with exercise group (G4). The subjects were 45.8$\pm$ 0.66 years old. BMI(kg/$m^2$) was 23.31 $\pm$ 0.63 in Gl group, 22.92 $\pm$ 0.51 in G2 group, 23.64 $\pm$ 0.61 in G3 group, 23.40 $\pm$ 0.37 in G4 group, and BMI of all groups were in normal value. Energy intake was 1332.28㎉/day, 60% of RDA, so that may be unbalance of micronutrients. Especially, calcium intake was 62.8% of RDA that was very low level. Osteocalcine was not statistically significant but calcium supplementation group (G3) be showed increase. BMD was usually decreased by Aging, but in this study was increased in the all group, except control group. It showed increase of BMD for calcium supplementation and/or exercise. Overall results indicate that calcium supplementation and/or exercise increased BMD of middle-aged women, but long-term calcium supplementation and exercise will be able to more effect.(Korean J Nutrition 35(9) : 962~969, 2002)

• 한국보건간호학회지
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• 제37권1호
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• pp.43-53
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• 2023

Purpose: This study aims to identify the factors influencing the depression of teachers in child day care centers. Methods: The study 181 teachers working at national/public or child day care centers certified by Seoul Metropolitan government in Seoul, South Korea. Data from September to October 2021, and emotional labor, job stress, ego resilience, stress resilience, and depression. Data were analyzed using t-test, ANOVA, Pearson's correlation coefficients, and stepwise multiple regression. Results: The average depression of child day care center's teachers 8.52±7.58 out of 60 points, and the depression group (above 21 points) was 9.4%. Depression in child day care center's teachers was positively correlated with job stress (r=.42, p<.001) and negatively correlated with ego resilience and stress resilience (r=-.55, p<.001). Factors affecting depression of child day care center's teachers were found to be job stress (p=0.005), ego resilience (p<.001), stress resilience (p=0.031) and the explanatory power of these variables was 39%. Conclusion: Results of this study indicate that in the future development of depression intervention programs for teachers of child day care centers, it is necessary to include measures that reduce job stress and strengthen ego resilience and stress resilience.

• 대한약학회:학술대회논문집
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• 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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• pp.272.1-272.1
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• 2001