• Journal of Pharmaceutical Investigation
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• 제1권1호
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• pp.101-108
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• 1971

The stability and toxicity test for p.p'-DDT, DDVP and dipterex that put to used sample in this study effects is follows A. about p.p'-DDT (1) In elevating the stability of p.p'-DDT, best stabilizing solvent was benzene. (2) The stability-agent has no difficulty as long as it not contain metal ion for instance $Z_n^{2+}$,$C_r^{3+}$,$Al^{3+}$,and $Fe^{2+or3+}$ but in case of contain $F_e^{3+}$, the combination of salicylaminoguanidine is best effective. (3) Using this product for water-suspension, We must use span 40 for stability agent and adding it at the same time. (4) We must use container which does not week alkali and metal ion but it is to preserved in tight light-resistant container. (5) The stopper of container is adapted with above-mentioned condition of container, but it is better not to use metal material. (6) This product needs opening ventilation more than 30 minutes after diffusion or spray and in the room we remove cause of remained poison by cleaning the bottom. B. about DDVP and Dipterex (1) Benzene or toluene in best solvent to preserve stability of DDVP and Dipterex. (2) Span 40 is superior for stability agent of this product and second is span 80. (3) The pH of solution is very stable in pH 5-6 and comparative stable in alkali more than p,p'-DDT. (4) Container is to preserved in tight, lightresistant container and especially be careful of outflow and inflow of water. (5) Because this product is centeral stimulant poison, we must pay attention to prevent cause of contact diadermic toxicity after use.

• 한국학교ㆍ지역보건교육학회지
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• 제13권1호
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• pp.77-87
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• 2012

This study is a descriptive paper addressing the relationship between test anxiety, self-esteem and the mental health levels of freshmen and third year students of Dental Hygienics. In late 2011, we received a total of 298 questionnaires from freshmen and third year Dental Hygienics students of three South Korean universities, located specifically in Seoul and Gyeonggi-do. The timing of this questionnaire was significant because it was one week prior to midterm examinations. The results were as follows:1. There was a statistically significant relationship between age (t=3.017, p<.001) and grade(t=2.665, p<0.05), subjective health status(t=27.513, p<.001). 2. The lower the participants' reported mental health in general, the higher their level of test anxiety (r=.565, p<.001), broken down into two subdivisions: cognitive text anxiety (r=526, p<.001) and emotional test anxiety (r=.534, p<.001). 3. When considering the factors that influence the general mental health of participants, there were age differences. For first year students, their subjeetive health status (${\ss}$=-.300, p<.001) and test anxiety (${\ss}$=.530, p<.001) were significant. For third year students, this was also true (subjective mental condition: ${\ss}$=-.242, p<.001 and test anxiety: ${\ss}$=.350, p<.001) but self-worth was also significant (${\ss}$=.377, p<.001). The results of this study suggest that the key factors that influence the mental health level of students Dental Hygienics are test anxiety, subjective appraisal of health level, and general self-worth. A systematic approach is therefore needed to improve students' mental health and reduce test anxiety. Health management programs which address and test students' physical health will also be important in improving student performance and welfare.

• 치위생과학회지
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• 제3권1호
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• pp.11-14
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• 2003

각종 토양시료로부터 M배지와 AMP배지에서 생육하는 500여종의 방선균을 분리하였으며, 그 중 전배양배지(GMY 배지)에서 가장 뛰어난 항암활성능을 소유한 균주를 불리하고 배양하여 세포외 항암성물질을 분리하여 이 물질을 완전정제하고 MTT 정량분석을 실시하여 암세포에 대한 세포독성검사를 실시하였다. 1. 정제는 배양한 균체를 완전히 제거하고 동량의 ethylacetate를 처리하여 배양액중의 항암성분을 추출하고 무수 magnesium sulfate로 건조 후 농축, ethanol로 용해, 10배량의 water을 첨가하여 $4^{\circ}C$에서 overnight 시킨 후 추출액을 원심분리(12,000 rpm, 30분)하여 methylene chloride로 용해시켜 silica gel 60 column(${\phi}35{\times}600mm$, Merck Co.), methylene chloride-ethanol(96:4) 용매로 용출하고 sephadex LH-20 column(${\phi}15{\times}300mm$, Pharmacia LKB)에서 100% methanol로 용출하여 HPLC(Waters, ODS)를 이용하여 최종적으로 완전 정제하였다. 2. Compound는 Gram(+) 세균(6균주), Gram(-) 세균(11균주), 효모(2균주), 곰팡이(1균주)에 대하여 항균 효과를 나타내었다. 3. 완전 정제된 물질에 대한 항암효과를 측정한 결과, 모든 실험 암세포에 대해서 뛰어난 항암효과를 나타내었으며 protein성 물질은 아닌 것으로 추정되었다.

• Child Health Nursing Research
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• 제5권1호
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• pp.5-17
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• 1999

This study was designed to determine the schemata and their characteristics of stress experience the subjectivity of stress experience(structure of subjectivity) would be a basic step for the effective clinical education through the stress management for characteristics of these types. Q-methodological method was used for that purpose. The research method statements were collected prior to the study through indepth interviews. For the study, 31 Q-statements were selected. There were 34 nursing students as subjects for the research. The 34 nursing students sorted the 31 statements using the principal of forced normal distribution. The principle of forced normal distribution, which has 9 scales to measure the individual opinions, was called. Q-factor analysis by using PC QUANL program supply the material. According to the outcomes of this study, there were 3 types of special opinion about the stress experience of clinical practice. The first type is called 'Influence of practical atmosphere type'. Members of this type experienced stress by an inadequate orientation and undesirable role model of nursing. The second type is called 'conflict of nursing role type'. Members of this type experienced stress by an inadequate orientation and undesirable role model of nursing. The third type is called 'Lack of confidence type'. Members of this type experienced stress because of a lack of confidence for their own nursing knowledge and skill. As a result, we now need further study to identify individual psychological aspects of stress for clinical practice. The findings will guide the development in effective approaches for clinical education. Finally, the result of the study will provide us the need for developing systematic and integrated practice education program for students and active involvement of clinical instructor.

• 한국조리학회지
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• 제23권5호
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• pp.169-177
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• 2017

Smoking bans at restaurants and bars have recently been introduced in Korea. Researchers and stakeholder are interested in the resulting changes in sales of restaurants and bars and their impact on overall national economy including employment. We examined the input-output tables (2013) issued by The Bank of Korea. The result showed that the production inducement coefficient was about 2.16; employment inducement coefficient was 13.1 for the restaurant and bar industry. The amount of inducement in the national production was calculated by 93,100 billion KRW. Employment inducement was calculated by 1,219,610 persons overall industries for a year. Assuming there comes a change (3%, 5%, 10%) in restaurant and bar production in consequence of the smoking bans, we computed following change in the national production and employment. The resulting changed in national production was 6,033 billion, 10,055 billion, and 20,110 billion KRW, respectively. The impact of employment overall industries was calculated 79,032, 131,720 and 263,441 persons, respectively.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제29권1호
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• pp.7-13
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• 2018

Objectives: Problem behaviors pose a great obstacle to daily functioning in children with neurodevelopmental deficits and are an important target for treatment. In this study, we translated the Behavior Problems Inventory (BPI)-01 into Korean language and tested its psychometric properties. Methods: We attained the approval of the BPI author and performed standard translation-back translation. Then, professional caregivers examined appropriateness according to cultural and situational contexts in order to make necessary modifications of the Korean version of the BPI. Results: The BPI-01, Korea-Scales of Independent Behavior-Revised (K-SIB-R), and Child Behavior Checklist were completed for 98 autistic spectrum disorder or intellectual development disorder participants (mean age=28.3, standard deviation=7.3, range=10.1-51.7). The inter-rater reliability of the BPI-01 was found to be high (r=0.992-1.000). As for the results for concurrent validity for subscale items of BPI-01 and scales of SIB, correlations between SIB and BPI-01 subscales were statistically significant (r=0.357-0.672). Discussion: The Korean version of the BPI-01 showed good psychometric properties with high reliability and sufficient convergent validity. Further examination of the validity of BPI-01 should be carried out with inclusion of younger aged children and a closer look at less frequently occurring symptoms.

• 보건행정학회지
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• 제19권4호
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• pp.1-17
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• 2009

The purpose of this study was to find factors affecting health of the rural residents. The data were collected from a sample of 2,587 people aged from 40 to 70 in the year 2005-2006, Wonju City and Pyeongchang County, Gangwon-do, Korea. The theoretical model adopted in this study was the Lalonde's health field(human biology, environment, lifestyle, and health care organization). SF-12 was used to measure subjective health status. In the category of human biology, men were healthier than women. Age and BMI showed negative relation to health status. Income, education and social support showed positive relation to health status in the environment category. In the category of life style, stress showed negative relation to health status. Medical expenses showed negative relation to health status in the category of health care organization. After converting SF-12 score to percentage score, the health determinants portions were 47% lifestyle, 26% environment, 18% human biology and 9% health care organization. These findings suggest that life style, environment and biology are main factors in determinants of health. Especially stress in the life style category is more focused for the community health promotion. We also may be able to improve income, education and social support in the environment category with self empowerment efforts, community supports and government helps. Finally greater attention must be payed to life style in the future health planning and budget allocation priority in the healthcare area.

• Archives of Plastic Surgery
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• 제39권6호
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• pp.593-599
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• 2012

Background This study aimed to investigate the possibility of isolating mesenchymal stem cells (MSCs) from human thigh adipose tissue and the ability of human thigh adipose stem cells (HTASCs) to differentiate into hepatocytes. Methods The adipose-derived stem cells (ADSCs) were isolated from thigh adipose tissue. Growth factors, cytokines, and hormones were added to the collagen coated dishes to induce the undifferentiated HTASCs to differentiate into hepatocyte-like cells. To confirm the experimental results, the expression of hepatocyte-specific markers on undifferentiated and differentiated HTASCs was analyzed using reverse transcription polymerase chain reaction and immunocytochemical staining. Differentiation efficiency was evaluated using functional tests such as periodic acid schiff (PAS) staining and detection of the albumin secretion level using enzyme-linked immunosorbent assay (ELISA). Results The majority of the undifferentiated HTASCs were changed into a more polygonal shape showing tight interactions between the cells. The differentiated HTASCs up-regulated mRNA of hepatocyte markers. Immunocytochemical analysis showed that they were intensely stained with anti-albumin antibody compared with undifferentiated HTASCs. PAS staining showed that HTASCs submitted to the hepatocyte differentiation protocol were able to more specifically store glycogen than undifferentiated HTASCs, displaying a purple color in the cytoplasm of the differentiated HTASCs. ELISA analyses showed that differentiated HTASCs could secrete albumin, which is one of the hepatocyte markers. Conclusions MSCs were islolated from human thigh adipose tissue differentiate to heapatocytes. The source of ADSCs is not only abundant abdominal adipose tissue, but also thigh adipose tissue for cell therapy in liver regeneration and tissue regeneration.

• 성인간호학회지
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• 제27권5호
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• pp.527-536
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• 2015

Purpose: The purpose of this study was to analyze the trend of nursing theories by Korean Journal of Adult Nursing (KJAN) for the last five years and to provide future directions for improvement. Methods: The study analyzed data collected from 323 research papers published in KJAN between 2010~2014. Descriptive analysis was conducted with a focus on frequency and percentage for the quantitative analysis. Qualitative analysis was performed for the analysis of nursing theories. Results: As for research topics, the analysis results based on the meta-paradigm of nursing show that the most frequent factors of analysis were adult patients in the area of human beings, hospitals in the area of environment, depression, anxiety, and suicide in the area of health, and all the influential factors in the area of nursing. The analysis results of uses of nursing theories in the papers reveal that only 4(1.2%) out of total 323 papers used the nursing theories, which indicates that the linkage and utilization of nursing theories in the published papers for the last five years were poor. Conclusion: We needs to make efforts at the society level to activate nursing theory utilization in research which is beloved to connect nursing practice, education, and research.

• 산업융합연구
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• 제18권2호
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• pp.9-18
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• 2020

본 연구의 목적은 간호대학생의 환자안전간호와 관련된 요인을 융·복합적 측면에서 체계적으로 고찰하고, 메타분석을 통해 관련 요인의 효과크기를 파악하는 것이다. 연구방법은 문헌검색은 Medline, Embases, CINAHL, DBpia, Research Information Service System(Riss), Korean Studies Information Service System(Kiss)을 이용하였으며, 국외 데이터베이스는 MeSH용어와 Emtree를 활용하여 검색하였다. 검색식은 [(patient safety or patient harm or safety management) and (students, nursing)] or [(patient safety or patient harm or safety management) and (education, nursing, graduate)] 이었다. 문헌선정은 PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)를 이용하였다. 연구결과 관련 요인으로는 간호수행, 지식, 태도, 자신감, 인식 및 인지 등이 확인되었고, 그 중 환자안전간호 수행과 관련성이 높은 요인에는 자신감, 태도, 인식, 지식 순으로 파악되었다.