• Archives of Pharmacal Research
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• v.25 no.4
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• pp.428-432
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• 2002

Three new dammarane glycosides were isolated from the processed ginseng (SG; Sun Ginseng). Their structure were determined to be $3{\beta},{\;}12{\beta}-dihydroxydammar-20(21),24-diene-3-O-{\beta}-D-glucopyranosyl(1{\;}{\rightarrow}{\;}2)-{\beta}-D-glucopyranoside;{\;}3{\beta},{\;}12{\beta}-dihydroxydammar-20(21),24-diene-3-O-{\beta}-D-{\;}glucopyranoside{\;}and{\;}3{\beta},6{\alpha},12{\beta}-trihydroxydammar-20(21),24-diene-6-O-{\beta}-D-glucopyranoside$ based on spectroscopic evidences. The compounds were named as ginsenoside $Rk_1,{\;}Rk_2,{\;}and{\;}Rk_3$ respectively.

• Journal of Industrial and Engineering Chemistry
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• v.67
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• pp.469-477
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• 2018

We describe surgical sutures enabled with the local, sustained delivery of a TGF-${\beta}$ inhibitory drug, tranilast. To fabricate drug-delivery sutures, we separately prepared a tranilast-loaded strand using poly (lactic-co-glycolic acid), which was then physically braided with a surgical suture already in clinical use. By this method, the drug-delivery sutures maintained the mechanical strength and allowed the modulation of drug release profiles by simply altering the tranilast-loaded strand. The drug-delivery sutures herein released tranilast for up to 14 days. When applied to animal models, scarring was indeed reduced with diminished TGF-${\beta}$ expression and fibroblast numbers during the entire 21 day testing period.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.3
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• pp.54-69
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• 2023

This study investigated the distribution of users in urban parks to overcome the limitations of existing research, which made it difficult to determine where data came was collected. It aimed to provide implications for park planning and management based on user distribution using mobile signal data. Five urban parks in Seongdong-gu, Seoul, with various physical characteristics, were selected. Mobile signal data provided by the Seoul Big Data Campus was used to identify the distribution of user inflow through hot spot analysis per park. The relationship between urban context and park influence area was derived. Seoul Forest (P1) and Seongsu Park (P3), which have a high proportion of commercial spaces around the park, showed wider user hotspots compared to Eungbong Park (P2), Dokseodang Park (P4), and Daehyunsan Park (P5), which were located in residential areas. Parks with a significant presence of commercial spaces had a broader influence, while parks with larger sizes and gentle slopes exhibited wider influence areas. This study proposed a novel data-based approach to urban park planning and management based on the inflow distribution of park users. Through this research, valuable insights were derived that could be utilized for urban park planning and management, aiming to enhance the effectiveness and efficiency of park utilization.

• Journal of Chest Surgery
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• v.54 no.6
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• pp.513-516
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• 2021

An 87-year-old man presented with a saccular aneurysm at the proximal descending thoracic aorta. As computed tomography revealed a shaggy aorta, we planned hybrid thoracic endovascular aortic repair (TEVAR) with embolic protection devices (EPDs) in both internal carotid arteries to prevent a cerebrovascular accident. We inserted an Emboshield NAV⁶ Embolic Protection System (Abbott Vascular, Abbott Park, IL, USA) into both internal carotid arteries before performing the TEVAR procedure. The patient was discharged from the hospital on postoperative day 4 without any neurological complications.

• Proceedings of the Korean Vacuum Society Conference
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• 2007.02a
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• pp.39-39
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• 2007

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.417.2-418
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• 2002

The rhGH-loaded PLGA microsphere formulation was prepared using a double emulsion process from hydrophilic 0:50 poly(D.L-lactide-co-glycolide) (PLGA) polymers. To investigate the sustained efficacy of this formulation, ts pharmacodynamic characteristics were analyzed. It showed particle size of ca 53.1 $\mu\textrm{m}$ with high drug ncorporation efficiency and it was sucutaneously administrated to hypophysectomized rats and whole body rowth responses of this formulation were compared to those of the different dosing patterns of rhGH. (omitted)

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.05a
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• pp.91-91
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• 2007

• 대한임상약리학회:학술대회논문집
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• 1998.12a
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• pp.36-36
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• 1998

• Proceedings of the Korean Society of Potoscience Conference
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• 2006.06a
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• pp.52-52
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• 2006

• Proceedings of the Korean Society of Toxicology Conference
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• 2005.05a
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• pp.187-187
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• 2005