Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.417.2-418
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- 2002
Effects of Sustained-Release Formulation of Recombinant Human Growth Hormone on Body weight. Bone growth and Organs in Hypophysectomized Rats
- Jo, Yeong-Woo (Research Laboratories, Dong-A Pharm. Co. Ltd.) ;
- Park, Yong-Man (College of Pharmacy Seoul National University) ;
- Lee, Ghun-Il (College of Pharmacy Seoul National University) ;
- Park, Yong-Man (College of Pharmacy Seoul National University) ;
- Yang, Hi-Chang (College of Pharmacy Seoul National University) ;
- Kim, Mi-Ryang (College of Pharmacy Seoul National University) ;
- Lee, Sung-Hee (College of Pharmacy Seoul National University) ;
- Kwon, Jong-Won (College of Pharmacy Seoul National University) ;
- Kim, Won-Bae (College of Pharmacy Seoul National University)
- Published : 2002.10.01
Abstract
The rhGH-loaded PLGA microsphere formulation was prepared using a double emulsion process from hydrophilic 0:50 poly(D.L-lactide-co-glycolide) (PLGA) polymers. To investigate the sustained efficacy of this formulation, ts pharmacodynamic characteristics were analyzed. It showed particle size of ca 53.1
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