Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2002.10a
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- Pages.417.1-417.1
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- 2002
Characterization of the rhGH released from rhGH-loaded PLGA microspheres
- Jo, Yeong-Woo (College of Pharmacy Seoul National University) ;
- Lee, Ghun-Il (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Park, Yong-Man (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Yang, Hi-Chang (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Kim, Mi-Ryang (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Lee, Sung-Hee (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Kwon, Jong-Won (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Kim, Won-Bae (Research Laboratories, Dong-A Pharm. Co. Ltd) ;
- Choi, Eung-Chil (Research Laboratories, Dong-A Pharm. Co. Ltd.)
- Published : 2002.10.01
Abstract
The in vitro release of rhGH from PLGA microspheres was characterized. rhGH-loaded PLGA microspheres were prepared with 50:50 poly(D.L-lactide-co-glycolide) (PLGA) polymers using a double emulsion process. To simulate rhGH release under physiological conditions. the microspheres were suspended in a physiological buller at 37
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