• Title/Summary/Keyword: Sensitivity Engineering

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Retrofit strategy issues for structures under earthquake loading using sensitivity-optimization procedures

  • Manolis, G.D.;Panagiotopoulos, C.G.;Paraskevopoulos, E.A.;Karaoulanis, F.E.;Vadaloukas, G.N.;Papachristidis, A.G.
    • Earthquakes and Structures
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    • v.1 no.1
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    • pp.109-127
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    • 2010
  • This work aims at introducing structural sensitivity analysis capabilities into existing commercial finite element software codes for the purpose of mapping retrofit strategies for a broad group of structures including heritage-type buildings. More specifically, the first stage sensitivity analysis is implemented for the standard deterministic environment, followed by stochastic structural sensitivity analysis defined for the probabilistic environment in a subsequent, second phase. It is believed that this new generation of software that will be released by the industrial partner will address the needs of a rapidly developing specialty within the engineering design profession, namely commercial retrofit and rehabilitation activities. In congested urban areas, these activities are carried out in reference to a certain percentage of the contemporary building stock that can no longer be demolished to give room for new construction because of economical, historical or cultural reasons. Furthermore, such analysis tools are becoming essential in reference to a new generation of national codes that spell out in detail how retrofit strategies ought to be implemented. More specifically, our work focuses on identifying the minimum-cost intervention on a given structure undergoing retrofit. Finally, an additional factor that arises in earthquake-prone regions across the world is the random nature of seismic activity that further complicates the task of determining the dynamic overstress that is being induced in the building stock and the additional demands placed on the supporting structural system.

Characterization of Hydrogen Gas Sensitivity of TiO2 Thin Films with Electron Beam Irradiation (전자빔 열처리에 따른 TiO2 박막의 수소가스 검출 특성 연구)

  • Heo, S.B.;Lee, H.M.;Jung, C.W.;Kim, S.K.;Lee, Y.J.;Kim, Y.S.;You, Y.Z.;Kim, D.
    • Journal of the Korean Society for Heat Treatment
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    • v.24 no.1
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    • pp.31-36
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    • 2011
  • $TiO_2$ films were deposited on a glass substrate with RF magnetron sputtering and then surface of $TiO_2$ films were electron beam irradiated in a vacuum condition to investigate the effect of electron bombardment on the thin film crystallization, surface roughness and gas sensitivity for hydrogen. $TiO_2$ films that electron beam irradiated at 450eV were amorphous phase, while the films irradiated at 900 eV show the anatase (101) diffraction peak in XRD pattern. AFM measurements show that the roughness is depend on the electron irradiation energy. As increase the hydrogen gas concentration and operation temperature, the gas sensitivity of $TiO_2$ and $TiO_2$/ZnO films is increased proportionally and $TiO_2$ films that electron beam irradiated at 900 eV show the higher sensitivity than the films were irradiated at 450eV. From the XRD pattern and AFM observation, it is supposed that the crystallization and rough surface promote the hydrogen gas sensitivity of $TiO_2$ films.

Increased Sensitivity to Chloramphenicol by Inactivation of manB in Streptomyces coelicolor

  • Rajesh, Thangamani;Song, Eunjung;Lee, Bo-Rahm;Park, Sung-Hee;Jeon, Jong-Min;Kim, Eunjung;Sung, Changmin;Lee, Jae-Hun;Yoo, Dongwon;Park, Hyung-Yeon;Kim, Yun-Gon;Kim, Byung-Gee;Yang, Yung-Hun
    • Journal of Microbiology and Biotechnology
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    • v.22 no.10
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    • pp.1324-1329
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    • 2012
  • Phosphomannomutase (ManB) is involved in the biosynthesis of GDP-mannose, which is vital for numerous processes such as synthesis of carbohydrates, production of alginates and ascorbic acid, and post-translational modification of proteins. Here, we discovered that a deletion mutant of manB (BG101) in Streptomyces coelicolor (S. coelicolor) showed higher sensitivity to bacteriostatic chloramphenicol (CM) than the wild-type strain (M145), along with decreased production of CM metabolites. Deletion of manB also decreased the mRNA expression level of drug efflux pumps (i.e., cmlR1 and cmlR2) in S. coelicolor, resulting in increased sensitivity to CM. This is the first report on changes in antibiotic sensitivity to CM by deletion of one glycolysis-related enzyme in S. coelicolor, and the results suggest different approaches for studying the antibiotic-resistant mechanism and its regulation.

A Projection-based Intensity Correction Method of Phased-Array Coil Images (위상 배열 코일 영상에서의 밝기 비균등성을 projection에 기반하여 수정하는 방법)

  • Yun SungDae;Chung Jun-Young;Han YeJi;Park HyunWook
    • Investigative Magnetic Resonance Imaging
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    • v.9 no.1
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    • pp.36-42
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    • 2005
  • Purpose : To develop a novel approach to calculate the sensitivity profiles of the phased array coil for use in non-uniform intensity correction. Materials and Methods : The proposed intensity correction method estimates the sensitivity profile of the coil to extract intensity variations that represent the scanned image. The sensitivity profile is estimated by fitting a non-linear curve to various angles of projections through the imaged object in order to eliminate the high-frequency image content. Filtered back projection is then used to compute the estimates of the sensitivity profile of each coil. The method was applied both to phantom and brain images from 8-channel phased-array coil and 4-channel phased-array coil, respectively. Results : Intensity-corrected images from the proposed method have more uniform intensity than those from the commonly used 'sum-of-squares' approach. By using the proposed correction method, the intensity variation was reduced to $6.1\%$ from $13.1\%$, acquired from the 'sum-of-squares'. Conclusion : The proposed method is more effective at correcting the intensity non-uniformity of the phased-array surface-coil images than the conventional 'sum-of-squares' method.

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Sensitivity Analysis for the Navier-Stokes Equations with Two-Equation Turbulence Models

  • 김창성;김종암;노오현
    • 한국전산유체공학회:학술대회논문집
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    • 2000.05a
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    • pp.66-72
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    • 2000
  • Aerodynamic sensitivity analysis is performed for the Navier-Stokes equations coupled with two-equation turbulence models using a discrete adjoint method and a direct differentiation method respectively. Like the mean flow equations, the turbulence model equations are also hand-differentiated to accurately calculate the sensitivity derivatives of flow quantities with respect to design variables in turbulent viscous flows. Both the direct differentiation code and the adjoint variable code adopt the same time integration scheme with the flow solver to efficiently solve the differentiated equations. The sensitivity codes are then compared with the flow solver in terms of solution accuracy, computing time and computer memory requirements. The sensitivity derivatives obtained from the sensitivity codes with different turbulence models are compared with each other. Using two-equation turbulence models, it is observed that a usual assumption of constant turbulent eddy viscosity in adjoint methods may lead to seriously inaccurate results in highly turbulent flows.

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Design Sensitivity Analysis of Elasto-perfectly-plastic Structure for Stiffened Shell Structure (탄성-완전-소성 보강쉘 구조물의 설계민감도해석)

  • Jung, Jae-Joon;Lee, Tae-Hee;Lim, Jang-Keun
    • Proceedings of the KSME Conference
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    • 2001.11a
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    • pp.746-752
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    • 2001
  • Design sensitivity analysis for nonlinear structural problems has been emerged in the last decade as a glowing area of engineering research. As a result, theoretical formulations and computational algorithms have already developed for design sensitivity of nonlinear structural problems. There is not enough research for practical nonlinear problems using multi-element, due to difficulties of implementation into FEA. Therefore, nonlinear response analysis for stiffened shell which consists of Mindlin plate and Timoshenko beam, was considered. Specially, it presents the backward-Euler method which is adopted to describe an exact yield state in the stress computation procedure. Then, design sensitivity analysis of nonlinear structures, particularly elasto-perfectly-plastic structure, is developed using direct differentiation method. The accuracy of the developed sensitivity analysis was compared with the central finite difference method. Finally, on the basis of above results, design improvement for stiffened shell is suggested.

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