• Title/Summary/Keyword: Sensitive to radiation

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Changes in the Characteristics of Wintertime Climatology Simulation for METRI AGCM Using the Improved Radiation Parameterization (METRI AGCM의 복사 모수화 개선에 따른 겨울철 기후모의의 특징적 변화)

  • Lim, Han-Cheol;Byun, Young-Hwa;Park, Suhee;Kwon, Won-Tae
    • Atmosphere
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    • v.19 no.2
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    • pp.127-143
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    • 2009
  • This study investigates characteristics of wintertime simulation conducted by METRI AGCM utilizing new radiation parameterization scheme. New radiation scheme is based on the method of Chou et al., and is utilized in the METRI AGCM recently. In order to analyze characteristics of seasonal simulation in boreal winter, hindcast dataset from 1979 to 2005 is produced in two experiments - control run (CTRL) and new model's run (RADI). Also, changes in performance skill and predictability due to implementation of new radiation scheme are examined. In the wintertime simulation, the RADI experiment tends to reduce warm bias in the upper troposphere probably due to intensification of longwave radiative cooling over the whole troposphere. The radiative cooling effect is related to weakening of longitudinal temperature gradient, leading to weaker tropospheric jet in the upper troposphere. In addition, changes in vertical thermodynamic structure have an influence on reduction of tropical precipitation. Moreover, the RADI case is less sensitive to variation of tropical sea surface temperature than the CTRL case, even though the RADI case simulates the mean climate pattern well. It implies that the RADI run does not have significant improvement in seasonal prediction point of view.

Protective effect of Hizikia fusiforme on radiation-induced damage in splenocytes (방사선을 조사한 마우스에서 비장세포에 대한 톳의 보호 작용)

  • Kim, Areum;Bing, So Jin;Cho, Jinhee;Ahn, Ginnae;Lee, Ji-Hyeok;Jeon, You-Jin;Lee, Byung-Gul;Jee, Youngheun
    • Korean Journal of Veterinary Research
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    • v.55 no.1
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    • pp.21-30
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    • 2015
  • The immune system is specifically sensitive to oxidative stress induced by ionizing radiation because of its rapid proliferative activity. For this reason, an instructive immune system is one of the best ways to minimize side effects, such immunodeficiency, of gamma radiation. Over the past few decades, several natural plants with antioxidant and immunomodulatory properties have been identified as adjuncts for nontoxic and successful radiotherapy. Hizikia fusiforme extract (HFE) containing plentiful dietary fiber and fucoidan is known for its instructive antioxidant capacity, immunomodulation abilities, and immune activation. In this study, we determined whether HFE protects radiosensitive immune cells from gamma radiation-induced damage. C57BL/6 mice were irradiated with gamma-ray. The effect of HFE on the ionizing radiation damage of immune cells was then evaluated with an MTT assay, 3H-thymidine incorporation assay, and PI staining. We found that HFE stimulated the proliferation of gamma-ray irradiated immune cells without cytotoxic effects. We also observed that HFE not only decreased DNA damage but also reduced gamma radiation-induced apoptosis of the immune cells. Our results suggest that HFE can protect immune cells from gamma-ray damage and may serve as an effective, non-toxic radioprotective agent.

Diffusion-Weighted MR Imaging in Biopsy-Proven Creutzfeldt-Jakob Disease

  • Hyo-Cheol Kim;Kee-Hyun Chang;In Chan Song;Sang Hyun Lee;Bae Ju Kwon;Moon Hee Han;Sang-Yun Kim
    • Korean Journal of Radiology
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    • v.2 no.4
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    • pp.192-196
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    • 2001
  • Objective: To compare conventional and diffusion-weighted MR imaging in terms of their depiction of the abnormalities occurring in Creutzfeldt-Jakob disease. Materials and Methods: We retrospectively analyzed the findings of conventional (T2-weighted and fluid-attenuated inversion recovery) and diffusion-weighted MR imaging in four patients with biopsy-proven Creutzfeldt-Jakob disease. The signal intensity of the lesion was classified by visual assessment as markedly high, slightly high, or isointense, relative to normal brain parenchyma. Results: Both conventional and diffusion-weighted MR images demonstrated bilateral high signal intensity in the basal ganglia in all four patients. Cortical lesions were observed on diffusion-weighted MR images in all four, and on fluid-attenuated inversion recovery MR images in one, but in no patient on T2-weighted images. Conventional MR images showed slightly high signal intensity in all lesions, while diffusion-weighted images showed markedly high signal intensity in most. Conclusion: Diffusion-weighted MR imaging is more sensitive than its conventional counterpart in the depiction of Creutzfeldt-Jakob disease, and permits better detection of the lesion in both the cerebral cortices and basal ganglia.

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The Analysis of Heat Transfer through the Multi-layered Wall of the Insulating Package

  • Choi, Seung-Jin
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.12 no.1
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    • pp.45-53
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    • 2006
  • Thermal insulation is used in a variety of applications to protect temperature sensitive products from thermal damage. Several factors affect the performance of insulation packages. Among these factors, the thermal resistance of the insulating wall is the most important factor to determine the performance of the insulating package. In many cases, insulating wall consists of multi-layered structure and the heat transfer through this structure is a very complex process. In this study, an one-dimensional mathematical model, which includes all of the heat transfer principles covering conduction, convection and radiation in multi-layered structure, were developed. Based on this model, several heat transfer phenomena occurred in the air space between the layer of the insulating wall were investigated. From the simulation results, it was observed that the heat transfer through the air space between the layer were dominated by conduction and radiation and the low emissivity of the surface of each solid layer of the wall can dramatically increase the thermal resistance of the wall. For practical use, an equation was derived for the calculation of the thermal resistance of a multi-layered wall.

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Measurement of the Surface Emissivity of the LED Lighting Module (LED 조명 모듈 표면의 방사율 측정에 관한 연구)

  • Park, Jin-Sung;Huh, Chang-Su
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.26 no.6
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    • pp.493-501
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    • 2013
  • LED lighting is sensitive because it made by semiconductor. So it has been researched about radiation of heat technologies for a long time. In addition, measurement and assessment a radiation of heat also conducted. It is necessary to get a date of accuracy temperature on the board after LED driven for measuring Junction temperature of the LED Lighting. For this research, we use 5 chip which is 4 W power on top of LED lighting board made by aluminum. Thermal camera effects to emissivity depending on material and property of the surface in LED board because it determines thermal energy which emitted from material surface. it is not only thermal camera has not a standard about emissivity. It has an error of temperature when emissivity was measured by thermal camera. we confirmed that emissivity and reflected temperature depending on color and quality of the surface throughout experiment.

Radiation Protective Effect of vitamin C and Cysteine on DNA Damage in Mice Splenic Lymphocytes by Single Cell Gel Electrophoresis Assay (단세포 겔 전기영동법을 이용한 생쥐 비장 림프구 DNA 손상에 대한 비타민 C 및 시스테인의 방사선 방어효과)

  • 천기정;김진규;김봉희
    • Environmental Analysis Health and Toxicology
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    • v.16 no.1
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    • pp.17-20
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    • 2001
  • The alkaline comet assay, employing a single-cell gel electrophoresis(SCGE), is a rapid, simple and sensitive technique for visualizing and measuring DNA damage leading to strand breakage in individual mammalian cells. The protecting effect of pretreatment with vitamin C and cysteine on the DNA damage of gamma ray was investigated in mice splenic lymphocytes. Vitamin C and cysteine were administered orally for five consecutive days before irradiation. Four week old ICR male mice were irradiated wish 3.5Gy of γ-radiation and were sacrificed 3 days later. Spleens were taken for DNA damage examination by Comet assay and the tail moments of DNA single -strand breaks in tole splenic lymphocytes were evaluated. The results show that pretreatment with vitamin C and cysteine were effective in protecting against DNA damage by gamma ray. Administration of antioxidants like vitamin C and cysteine to mice before irradiation was effective in reducing the tail moment of splenic lymphocytes DNA.

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Selection of 5-Methyltryptophan and S-(2-Aminoethyl)-L-Cysteine Resistant Microspore-Derived Rice Cell Lines Irradiated with Gamma Rays

  • Kim, Dong-Sub;Lee, In-Sok;Jang, Cheol-Seong;Hyun, Do-Yoon;Lee, Sang-Jae;Seo, Yong-Weon;Lee, Young-Il
    • Journal of Plant Biotechnology
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    • v.5 no.1
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    • pp.33-41
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    • 2003
  • Microspore-derived cell lines resistant to 5-methyltryptophan (5MT, a tryptophan analog) or S-(2-aminoethyl)-L-cysteine (AEC, a Iysine analog) were selected in rice by in vitro mutagenesis. For selection of 5MT or AEC resistant cell lines, suspension-cultured cells were irradiated with gamma rays. Thirteen 5MT resistant cell lines were selected and they were able to grow stably at 2 times higher 5MT concentration. A feedback insensitive form of anthranilate synthesis, the pathway specific control enzyme for tryptophan synthesis, was detected from the 5MT resistant lines. Contents of the free amino acids in five resistant lines (MR12-1 to MR12-5) showed a 7.4 to 46.6 times greater level than that in the control culture. Tryptophan, phenylalanine, and tyrosine levels in the shikimate pathway were 28.1 and 22.5 times higher in MR12-3 and MR12 4, respectively, than that measured in the control cells. Four AEC resistant cell lines were isolated from cultures grown on medium containing 1 mM AEC, They were able to grow stably with 2 mM AEC, while sensitive calli were inhibited by 0.5 mM AEC. Aspartate kinase activities of the resistant lines were insensitive to the natural inhibitor, Iysine, and accumulated 2.2 to 12.9-fold higher levels of free Iysine than that of the control cells. Especially, the levels of aspartate, asparagine, and methionine in the aspartate pathway showed higher accumulation in the AEC resistant lines than that in the control cells.

Automated radiation field edge detection in portal image using optimal threshold value (최적 문턱치 설정을 이용한 포탈영상에서의 자동 에지탐지 기법에 관한 연구)

  • 허수진
    • Journal of Biomedical Engineering Research
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    • v.16 no.3
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    • pp.337-344
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    • 1995
  • Because of the high energy of the treatment beam, contrast of portal films is very poor. Many image processing techniques have been applied to the portal images but a significant drawback is the loss of definition on the edges of the treatment field. Analysis of this problem shows that it may be remedied by separating the treatment field from the background prior to enhancement and uslng only the pixels within the field boundary in the enhancement procedure. A new edge extraction algorithm for accurate extraction of the radiation field boundary from portal Images has been developed for contrast enhancement of portal images. In this paper, portal image segmentation algorithm based on Sobel filtration, labelling processes and morphological thinning has been presented. This algorithm could automatically search the optimal threshold value which is sensitive to the variation of the type and quality of portal images.

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AN EXPERMENTAL STUDY ON THE EFFECTS OF COBALT-60 RADIATION OF THE TEETH OF THE RAT (Co-60 방사선 조사가 백서 치아에 미치는 영향에 관한 실험적 연구)

  • Lee, Chan-Young
    • Restorative Dentistry and Endodontics
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    • v.8 no.1
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    • pp.61-68
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    • 1982
  • This study was undertaken to compare the histopathological effects of the fractionated doses of 2,400, 4,800 and 7,200 rads of Cobalt-60 irradiation on the teeth of the sixty eight rats (Wester strain), weighing approximately 130gm. They were devided into four groups; no irradiation as a control (Group I) and others (Group II, III, and IV) which received different doses of radiation using 1.25 Mev RAC-120 Cobalt-60 Teletherapy Unit with exposure dose rate 69 rads/min, TSD 80cm. Experimental animals received 600 rads every three days until the total dosage of their groups were reached. Experimental animals were sacrified at the 1st day, 1st, 2nd, 3rd, 4th, 5th and 6th week irradiation. The following histopathologic findings were obtained: 1. The Group II, received 2,400 rads, showed no histopamologic changes essentially same as those of the control Group. 2. In the Groups III and IV, received 4,800 rads and 7,200 rads, disarray of the normal palasading arrangement of the odontoblastic cells, vacuolar degeneration in the odontoblastic layer, osteodentin and dentinal niches in the anterior teeth were observed. 3. There were no distinct changes in the posterior teeth in the Groups III and IV. 4. The ameloblast cells seemed to be less sensitive to radiation damage than the odontoblast cells.

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RESULTS OF THE TOTAL DOSE EXPERIMENT ON KITSAT-1 (우리별 1호에서의 총 방사선 측정 실험)

  • 이대희;신영훈;민경욱
    • Journal of Astronomy and Space Sciences
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    • v.14 no.1
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    • pp.80-86
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    • 1997
  • High energy particles in the earth's radiation belts cause transient and long term effects on electronic materials, devices, and integrated circuits on board the satellites. Hence, it is very important to have the information on the space radiation environment and the damage on the electronics caused by the se high energy particles. One of the radiation monitor devices frequently used in space is RADFET, a specially designed MOSFET with a thick gate oxide region. The present study focuses on the calibration of RADFET TOT500 using the $Co^{60}{\gamma}-ray$ source. The result shows that the response of RADFET is very sensitive to the change of temperature. The peculiar behavior observed in the TDE (Total Dose Experiment) on board the KITSAT-1 is identified as the thermal effect due to the change in the eclipse rate of the satellite.

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