• Korean Journal of Adult Nursing
• /
• v.26 no.4
• /
• pp.393-402
• /
• 2014

Purpose: The aim of this study was to describe the risk of dysphagia among older adults in senior centers and to find the relationships between the risk of dysphagia and dysphagia-specific quality of life. Methods: The participants were 260 community-dwelling older adults, aged 65 years in two senior centers. Data were collected by self-report questionnaires or face to face interviews. The instruments were the modified dysphagia risk assessment scale for elderly and dysphagia-specific quality of life questionnaire. The data were analyzed using t-test, $x^2$-test, logistic regression, and pearson's correlation. Results: 162 older adults (62.3%) were classified as having the risk of dysphagia. Severe dry mouth (OR=15.677, CI=2.986~82.297), neurologic disease (OR=10.125, CI=1.092~93.899), gastritis (OR=5.731, CI=1.482~22.173), denture discomfort (OR=2.969, CI=1.016~8.677), teeth discomfort (OR=2.61, CI=1.311~5.196) were the significant factors predicting the risk of dysphagia. There is a significant correlation between the risk of dysphagia and dysphagia-specific quality of life. Conclusion: Dysphagia could be a major health problem among community dwelling older adults. It can affect the dysphagia-specific quality of life. Older adults having severe dry mouth, neurologic disease, or gastritis should receive dysphagia risk assessment and proper management on a regular basis. An effective nursing intervention needs to be developed for the older adults with risk factors of dysphagia.

• The Journal of Korean society of community based occupational therapy
• /
• v.2 no.1
• /
• pp.37-47
• /
• 2012

Objective : The purpose of this study was to identify Effects of the ROM dance on cognitive function, neuropsychiatric in using wheelchair senior in nursing home. Methods : The subjects of the experimental group were 15 seniors using wheelchair who attended an ROM dance program in a nursing home. It was carried out for 18 weeks from Mar. 2010. to August. 2010. The evaluation tools used for the presented study were the Mini-Mental Status Exam-Korean(MMSE-K) and Neuropsychiatric Inventory-Questionaire (NPI-Q). Results : In the terms of cognitive function there was no significant defference between the mean pre/post test. but the factor(orientation of time) of MMSE-K and the factors 2 (sleep/nighttime behavios, apathy/indefference) of NPI-Q was significant improvement. Conclusion : In this study, the ROM dance program was effective in improving cognitive function and neuropsychiatric in seniors using wheelchair. also ROM dance program was decreasing and regression delay effect in cognitive and neuropsychiatric.

• Journal of Microbiology and Biotechnology
• /
• v.28 no.2
• /
• pp.236-245
• /
• 2018

Ingredients of soy and fermented soy products have been widely utilized as food supplements for health-enhancing properties. The aim of this study was to evaluate the effects of fermented soymilk (FSM) and soymilk (SM) on free fatty acid-induced lipogenesis in the hepatocellular steatosis model. HepG2 cells were incubated with palmitic acid (PA) for 24 h to induce lipogenesis and accumulation of intracellular lipid contents. The PA-treated cells were co-incubated with FSM, SM, genistein, and estrogen, respectively. Lipid accumulation in the PA-treated HpG2 cells was significantly decreased by co-incubation with FSM. Treatment of HepG2 cells with PA combined with genistein or estrogen significantly increased the expression of SREBP-1. However, FSM co-incubation significantly attenuated SREBP-1 expression in the PA-treated HepG2 cells; in addition, expression of NRF-2 and phosphorylation of ERK were significantly increased in the PA and FSM co-incubated cells. PA-induced ROS production was significantly reduced by FSM and SM. Our results suggested that the bioactive components of FSM could protect hepatocytes against the lipid accumulation and ROS production induced by free fatty acids. These effects may be mediated by the inhibition of SREBP-1 and the activation of NRF-2 via the ERK pathway in HepG2 cells.

• Biomedical Science Letters
• /
• v.21 no.3
• /
• pp.152-159
• /
• 2015

Der p 2, which is a major allergen of house dust mite, plays an important role in the pathogenesis of allergic disease. There is controversy regarding whether Der p 2 binds to Toll-like receptor 4 (TLR4), and its inflammatory effect has not yet been elucidated. In the current study, we examined the interaction of Der p 2 with TLR4 and the effect of Der p 2 on cytokine release in THP-1 cells and lymphocytes. Among house dust mite extracts, recombinant TLR4 protein interacted with Der p 2. The overall structure of Der p 2 is characteristic of the immunoglobulin superfamily and contains ten ${\beta}-strands$, forming a ${\beta}-cup$ fold with two anti-parallel ${\beta}-sheets$, and a short 310 helix. The two sheets can be separated, further allowing the formation of a large internal pocket, which is narrow and suitable for binding large flat molecules such as lipid-like molecules. Der p 2 caused increased secretion of IL-6, IL-8, and MCP-1, which are neutrophil survival factors, in human monocytic THP-1 cells in a time-dependent manner. Der p 2 also induces the release of cytokines in normal and allergic lymphocytes. Supernatant after treatment with Der p 2 inhibited neutrophil apoptosis. In coculture of lymphocytes with neutrophils, Der p 2 inhibited spontaneous apoptosis of allergic neutrophils. In summary, Der p 2 binds to TLR4 and induces an inflammatory response such as cytokine secretion in immune cells. These findings may enable elucidation of allergy pathogenesis by specific allergen of house dust mite.

• Journal of Family Resource Management and Policy Review
• /
• v.12 no.3
• /
• pp.23-43
• /
• 2008

This research investigates the effect of leisure activities on lifestyle satisfaction of senior citizens. The target of this research is 202 people over 60 years of age who live in Seoul. Collected data was analyzed using frequency, percentage, average, T-test, one-way ANONA, and logistic regression analysis. SPSS and the Excel PC Program were used for the analysis. The following is the summary of the result of this research. First - in terms of participation in leisure activities: more active participation is observed with the elderly who have a spouse than with those who do not in every kind of leisure activity (except for the pastime activities). Second - all of the variables indicating the level of satisfaction from activities of the seniors who have a spouse are by far higher than those of the elderly who have no spouse. Third - the leisure activities and the satisfaction from the activities prove affective variables on whether they have a spouse or not. Notably, the religious leisure activities are enjoyed more by those senior citizens who are married. Comparatively, the unmarried senior citizens participate more actively in recreational and pastime leisure activities. This study suggests various practical means to promote leisure activities to the elderly and to raise the level of satisfaction received from those activities, as well as to help those who are concerned with understanding and improving lifestyle satisfaction of the elderly population. Nonetheless, this analysis is limited due to the restriction on the number of objects and samples studied. Therefore, studies to analyze leisure activities by regions in order to account for a more balanced set of systematical tools should follow.

• The Journal of the Korea Contents Association
• /
• v.13 no.4
• /
• pp.339-349
• /
• 2013

This study was undertaken to investigate the degree of career satisfaction and its affecting factors for senior nursing students. The subjects were 131 senior nursing students from one college located in Seoul. The data analyzed by using SPSS-WIN 18.0 program. Career satisfaction showed a significant positive correlation with recognition of career related to major(r=.690, p<.001), learning preference related to major(r=.666, p<.001), participation of activities related to major(r=.537, p<.001), major performance(r=.231, p=.008), concentration of major(r=.508, p<.001), intrinsic motivation(r=.357, p<.001), problem solving ability(r=.452, p<.001), satisfaction of laboratorial practice(r=.476, p<.001) and satisfaction of clinical practice(r=.410, p<.001). In addition, recognition of career, learning preference, participation of activities, concentration of major, and satisfaction of laboratorial practice were significant predictors to explain career satisfaction(63%). It is necessary to develop an effective career guidance program to improve career satisfaction considering these findings.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.15 no.2 s.38
• /
• pp.115-126
• /
• 1991

The purpose of this study was to investigate the relationship between Sex Role attitude and childrens clothing behavior for senior childhood years upon two regions-city of Wonju and Mokpo-The questionnaires were administered to 315 elementary school children in Mokpo and 268 in Wonju. This data was analyze ststistically using to pearson's correlation, ANOVA (one-way or two-way) and Multiple Classification Analyze. The major findings of this research can be summarize as followings: 1. There are significant relationships between the unisex clothing behavior and the sex role attitude subscales. Liberal attitude toward sex role were positively related to unisex clothing behavior for senior childhood years children. 2. There are significant positive correlationships between the attitude of solving problem and comfort, autonomy, linterest and management. 3. The Sex and Grade have significants effect on the sex role attitude in two regios. Girls exhibited higher liberal attitudes toward sex role than boys. 4. The Sex have significant effects on clothing behavior and Grade have partially significant effect on clothing behavior. 5. The equality of the sexes attitude is significant relationships among the sex role attitude subscales except attitude of solving problems. There are significant inter relationships between the family role, occupation role and play role among the sex role subscales. 6. There are significant positive correlations between the unisex clothing behavior and conformity. And significant negative correlations between comfort and the unisex clothing behavior. Comfort is related to autonomy and management. Management is related to auton-omy and interest. 7. There are significant differences in sex role attitude according to two regions.

• Research in Community and Public Health Nursing
• /
• v.32 no.4
• /
• pp.457-466
• /
• 2021

Purpose: The purpose of this study was to examine the correlations among emotional perception clarity, emotion regulation, family relationship, non-suicidal self-injury, and depression, and to determine associated factors of non-suicidal self-injury and depression for senior elementary school students. Methods: Data were collected from 150 early adolescences in K region, Korea. A self-report questionnaire consisted of Trait Meta-Mood Scale, Cognitive Emotion Regulation Questionnaire, Family Relationship Assessment Scale, Functional Assessment of Self-Mutilation, and Children's Depression Inventory. The data were analyzed using t-test, Pearson's correlation coefficient, logistic regression, and multiple regression analysis. Results: Non-suicidal self-injury and depression were positively associated with maladaptive emotion regulation strategy and family conflict, but negatively related to emotional perception clarity and family support. Adaptive emotion regulation strategy and family togetherness were only significantly correlated with depression. In logistic regression analysis, significant predictors of non-suicidal self-injury were emotional perception clarity, maladaptive emotion regulation strategy, and family support. Multiple regression analysis found that significant factors of depression were adaptive and maladaptive emotion regulation strategies, which explained 38.0% of the variance. Conclusion: Our study findings suggest that targeted intervention to reinforce the adaptive emotion regulation strategy and family relationship may prevent non-suicidal self-injury, and depression for senior elementary school students.

• Journal of Digital Convergence
• /
• v.20 no.2
• /
• pp.553-561
• /
• 2022

The purpose of this study is to understand the relationship between anxiety, sleep disturbance, and suicide ideation in the elderly using senior welfare centers and to identify factors influencing suicide ideation. Data were collected from January 6 to February 7, 2020 from 206 elders who analyzed using SPSS/Win 25.0 with descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, multiple regression analysis. anxiety, sleep disturbance, suicide ideation were positively correlated. Meanwhile, factor affecting suicide ideation were anxiety(β=.215, p=.001), sleep disturbance(β=.383, p<.001) and the explanatory power of suicide ideation was 27.3%. Therefore, in order to prevent suicide ideation, it will be necessary to develop an intervention program to maintain qualitative sleep and lower anxiety levels.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.22 no.1
• /
• pp.72-82
• /
• 2016

Purpose: The purpose of this study was to identify the effects of health status and health management on activities of daily living (ADL) in older, urban-dwelling Koreans. Methods: A total of 206 subjects were recruited from one senior welfare center, six senior citizen centers, and subjects' home in two cities. Data was collected with self-reported questionnaires in order to measure health management, health status, and ADL. Data was analyzed by t-test, ANOVA, and stepwise multiple linear regression using SPSS/WIN 22.0. Results: ADL in this subject were different depending on their age, education, marital status, type of family, and average monthly living expenses. Multivariate analysis showed that age (${\beta}=-0.35$, p<.001), exercise ability (${\beta}=0.20$, p<.001), diabetes (${\beta}=-0.17$, p<.001), osteoarthritis (${\beta}=-0.15$, p<.001), caregiver (${\beta}=0.14$, p=.005), frequency of health management (${\beta}=-0.13$, p=.006), smoking (${\beta}=-0.11$, p=.019), hypertension (${\beta}=-0.10$, p=.027), and type of family (${\beta}=-0.10$, p=.036) were significantly associated with ADL. Overall, approximately 60.2% of total variability in ADL could be explained by the 11 variables in this model ($R^2=0.602$, F=32.06, p<.001). Conclusion: This study suggests that individualized health care should be continued for older, community-dwelling Koreans in order to improve their ADL. Moreover, we need to develop self-care programs and encourage them to participate in those programs.