• Asian-Australasian Journal of Animal Sciences
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• 제26권5호
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• pp.603-608
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• 2013

Hanwoo have been subjected over the last seventy years to intensive artificial selection with the aim of improving meat production traits such as marbling and carcass weight. In this study, we performed a signature of selection analysis to identify recent positive selected regions driven by a long-term artificial selection process called a breeding program using whole genome SNP data. In order to investigate homozygous regions across the genome, we estimated iES (integrated Extended Haplotype Homozygosity SNP) for the each SNPs. As a result, we identified two highly homozygous regions that seem to be strong and/or recent positive selection. Five genes (DPH5, OLFM3, S1PR1, LRRN1 and CRBN) were included in this region. To go further in the interpretation of the observed signatures of selection, we subsequently concentrated on the annotation of differentiated genes defined according to the iES value of SNPs localized close or within them. We also described the detection of the adaptive evolution at the molecular level for the genes of interest. As a result, this analysis also led to the identification of OLFM3 as having a strong signal of selection in bovine lineage. The results of this study indicate that artificial selection which might have targeted most of these genes was mainly oriented towards improvement of meat production.

• Journal of Information Processing Systems
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• 제10권4호
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• pp.555-567
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• 2014

Biometric performance improvement is a challenging task. In this paper, a hierarchical strategy fusion based on multimodal biometric system is presented. This strategy relies on a combination of several biometric traits using a multi-level biometric fusion hierarchy. The multi-level biometric fusion includes a pre-classification fusion with optimal feature selection and a post-classification fusion that is based on the similarity of the maximum of matching scores. The proposed solution enhances biometric recognition performances based on suitable feature selection and reduction, such as principal component analysis (PCA) and linear discriminant analysis (LDA), as much as not all of the feature vectors components support the performance improvement degree.

• Animal Bioscience
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• 제37권3호
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• pp.461-470
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• 2024

Objective: The objective of this study was to investigate the genetic diversity, population structure and whole-genome selection signatures of Luxi cattle to reveal its genomic characteristics in terms of meat and carcass traits, skeletal muscle development, body size, and other traits. Methods: To further analyze the genomic characteristics of Luxi cattle, this study sequenced the whole-genome of 16 individuals from the core conservation farm in Shandong region, and collected 174 published genomes of cattle for conjoint analysis. Furthermore, three different statistics (pi, F_st, and XP-EHH) were used to detect potential positive selection signatures related to selection in Luxi cattle. Moreover, gene ontology and Kyoto encyclopedia of genes and genomes pathway enrichment analyses were performed to reveal the potential biological function of candidate genes harbored in selected regions. Results: The results showed that Luxi cattle had high genomic diversity and low inbreeding levels. Using three complementary methods (pi, F_st, and XP-EHH) to detect the signatures of selection in the Luxi cattle genome, there were 2,941, 2,221 and 1,304 potentially selected genes identified, respectively. Furthermore, there were 45 genes annotated in common overlapping genomic regions covered 0.723 Mb, including PLAG1 zinc finger (PLAG1), dedicator of cytokinesis 3 (DOCK3), ephrin A2 (EFNA2), DAZ associated protein 1 (DAZAP1), Ral GTPase activating protein catalytic subunit alpha 1 (RALGAPA1), mediator complex subunit 13 (MED13), and decaprenyl diphosphate synthase subunit 2 (PDSS2), most of which were enriched in pathways related to muscle growth and differentiation and immunity. Conclusion: In this study, we provided a series of genes associated with important economic traits were found in positive selection regions, and a scientific basis for the scientific conservation and genetic improvement of Luxi cattle.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제9권12호
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• pp.411-418
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• 2020

정보보안을 위한 IDS(Intrusion Detection Systems)는 통상적으로 서명기반(signature based) 침입탐지시스템과 이상기반(anomaly-based) 침입 탐지시스템으로 분류한다. 이 중에서도 네트워크에서 발생하는 트래픽 데이터를 기계학습으로 분석하는 이상기반 IDS 연구가 활발하게 진행됐다. 본 논문에서는 공격 유형 학습에 사용되는 데이터에 존재하는 희소 클래스 문제로 인한 성능 저하를 해결하기 위한 전처리 방안에 대해 연구했다. 희소 클래스(Rare Class)와 준 희소 클래스(Semi Rare Class)를 기준으로 데이터를 재구성하여 기계학습의 분류 성능의 개선에 대하여 실험했다. 재구성된 3종의 데이터 세트에 대하여 Wrapper와 Filter 방식을 연이어 적용하는 하이브리드 특징 선택을 수행한 이후에 Quantile Scaler로 정규화를 처리하여 전처리를 완료한다. 준비된 데이터는 DNN(Deep Neural Network) 모델로 학습한 후 TP(True Positive)와 FN(False Negative)를 기준으로 분류 성능을 평가했다. 이 연구를 통해 3종류의 데이터 세트에서 분류 성능이 모두 개선되는 결과를 얻었다.

• 정보보호학회논문지
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• 제30권3호
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• pp.357-367
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• 2020

2018년 시만텍 보고서에 따르면, 모바일 환경에서 변종 악성 앱은 전년도 대비 54% 증가하였고, 매일 24,000개의 악성 앱이 차단되고 있다. 최근 연구에서는 기존 악성 앱 분석 기술의 사용 한계를 파악하고, 신·변종 악성 앱을 탐지하기 위하여 기계학습을 통한 악성 앱 탐지 기법이 연구되고 있다. 하지만, 기계학습을 적용하는 경우에도 악성 앱의 특성을 적절하게 선택하여 학습하지 못하면 올바른 결과를 보일 수 없다. 본 연구에서는 신·변종 악성 앱의 특성을 찾아낼 수 있도록 개선된 특성 선택 방법을 적용하여 학습 모델의 정확도를 최고 98%까지 확인할 수 있었다. 향후 연구를 통하여 정밀도, 재현율 등 특정 지표의 향상을 목표로 할 수 있다.

• International Journal of Costume and Fashion
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• 제15권1호
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• pp.51-74
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• 2015

The purpose of this exploratory research is to study Cashin's fashion philosophy and to draw her design characteristics through analysis of her work. As a result of this research, 76 garment pieces were selected from the 180 Bonnie Cashin collections at the University of Cincinnati to document and evaluate. The final selection includes: sixteen jackets, fifteen skirts, five pants, five tops, seven dresses, twenty five coats, and three capes. Bonnie Cashin specialized in practical and functional; yet innovative designs such as leather trimmed tweed Jackets/coats, canvas raincoats, suede leather coats, and ponchos. Her trademark elements include toggle closures, oversized pockets, her Noh coats, tweed suits, canvas raincoats, fringed suede dresses, funnel neck pullovers, jersey dresses, and ponchos. She emphasized function and comfort and she believed that a good design must also be practical. The examination of these 76 pieces from the University of Cincinnati's private Bonnie Cashin Collection brings to light Bonnie Cashin's creative design and what she represented in the development of American fashion design in the $20^{th}$ century.

• 한국융합학회논문지
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• 제9권11호
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• pp.75-81
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• 2018

블록체인 내의 모든 트랜잭션이 공개되기 때문에 익명성과 프라이버시 문제는 중요해지고 있다. 공개 블록체인은 사용자 대신 공개키 주소를 사용하여 익명성을 보장하는 것처럼 보이지만 트랜잭션 그래프를 기반으로 다양한 기법을 통해 추적함으로써 익명성을 약화시킬 수 있다. 본 논문에서는 블록체인 환경에서 익명성과 프라이버스를 보호하기 위하여 다양한 보안 기법을 융합하여 사용자의 추적을 어렵게 하는 기법을 제안한다. 제안 기법은 k-anonymity 기술, 믹싱 기술, 은닉서명, 다단계 기법, 램덤 선택기법, 영지식 증명 기법 등을 융합하여 인센티브 및 기여자의 참여를 통해 익명성과 프라이버시를 보호한다. 성능 분석을 통해 제안기법은 기여자의 수가 공모자의 수보다 많은 환경에서는 공모를 통한 프라이버시 및 익명성 훼손이 어렵다는 것을 보였다.

• Asian-Australasian Journal of Animal Sciences
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• 제33권9호
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• pp.1378-1386
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• 2020

Objective: Chinese indigenous sheep breeds can be classified into the following three categories by their tail morphology: fat-tailed, fat-rumped and thin-tailed sheep. The typical sheep breeds corresponding to fat-tailed, fat-rumped, and thin-tailed sheep are large-tailed Han, Altay, and Tibetan sheep, respectively. Detection of copy number variation (CNV) and selection signatures provides information on the genetic mechanisms underlying the phenotypic differences of the different sheep types. Methods: In this study, PennCNV software and F-statistics (F_ST) were implemented to detect CNV and selection signatures, respectively, on the X chromosome in three Chinese indigenous sheep breeds using ovine high-density 600K single nucleotide polymorphism arrays. Results: In large-tailed Han, Altay, and Tibetan sheep, respectively, a total of six, four and 22 CNV regions (CNVRs) with lengths of 1.23, 0.93, and 7.02 Mb were identified on the X chromosome. In addition, 49, 34, and 55 candidate selection regions with respective lengths of 27.49, 16.47, and 25.42 Mb were identified in large-tailed Han, Altay, and Tibetan sheep, respectively. The bioinformatics analysis results indicated several genes in these regions were associated with fat, including dehydrogenase/reductase X-linked, calcium voltage-gated channel subunit alpha1 F, and patatin like phospholipase domain containing 4. In addition, three other genes were identified from this analysis: the family with sequence similarity 58 member A gene was associated with energy metabolism, the serine/arginine-rich protein specific kinase 3 gene was associated with skeletal muscle development, and the interleukin 2 receptor subunit gamma gene was associated with the immune system. Conclusion: The results of this study indicated CNVRs and selection regions on the X chromosome of Chinese indigenous sheep contained several genes associated with various heritable traits.

• Journal of Animal Science and Technology
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• 제56권7호
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• pp.23.1-23.7
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• 2014

Background: Scanning of the genome for selection signatures between breeds may play important role in understanding the underlie causes for observable phenotypic variations. The discovery of high density single nucleotide polymorphisms (SNPs) provide a useful starting point to perform genome-wide scan in pig populations in order to identify loci/candidate genes underlie phenotypic variation in pig breeds and facilitate genetic improvement programs. However, prior to this study genomic region under selection in commercially selected Berkshire and Korean native pig breeds has never been detected using high density SNP markers. To this end, we have genotyped 45 animals using Porcine SNP60 chip to detect selection signatures in the genome of the two breeds by using the $F_{ST}$ approach. Results: In the comparison of Berkshire and KNP breeds using the FDIST approach, a total of 1108 outlier loci (3.48%) were significantly different from zero at 99% confidence level with 870 of the outlier SNPs displaying high level of genetic differentiation ($F_{ST}{\geq}0.490$). The identified candidate genes were involved in a wide array of biological processes and molecular functions. Results revealed that 19 candidate genes were enriched in phosphate metabolism (GO: 0006796; ADCK1, ACYP1, CAMK2D, CDK13, CDK13, ERN1, GALK2, INPP1; MAK, MAP2K5, MAP3K1, MAPK14, P14KB, PIK3C3, PRKC1, PTPRK, RNASEL, THBS1, BRAF, VRK1). We have identified a set of candidate genes under selection and have known to be involved in growth, size and pork quality (CART, AGL, CF7L2, MAP2K5, DLK1, GLI3, CA3 and MC3R), ear morphology and size (HMGA2 and SOX5) stress response (ATF2, MSRB3, TMTC3 and SCAF8) and immune response (HCST and RYR1). Conclusions: Some of the genes may be used to facilitate genetic improvement programs. Our results also provide insights for better understanding of the process and influence of breed development on the pattern of genetic variations.

• 정보처리학회논문지:소프트웨어 및 데이터공학
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• 제10권2호
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• pp.65-72
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• 2021

최근 네트워크 환경에 대한 공격이 급속도로 고도화 및 지능화 되고 있기에, 기존의 시그니처 기반 침입탐지 시스템은 한계점이 명확해지고 있다. 이러한 문제를 해결하기 위해서 기계학습 기반의 침입 탐지 시스템에 대한 연구가 활발히 진행되고 있다. 하지만 기계학습을 침입 탐지에 이용하기 위해서는 두 가지 문제에 직면한다. 첫 번째는 실시간 탐지를 위한 학습과 연관된 중요 특징들을 선별하는 문제이며, 두 번째는 학습에 사용되는 데이터의 불균형 문제로, 기계학습 알고리즘들은 데이터에 의존적이기에 이러한 문제는 치명적이다. 본 논문에서는 위 제시된 문제들을 해결하기 위해서 Hybrid Feature Selection과 Data Balancing을 통한 심층 신경망 기반의 네트워크 침입 탐지 모델인 HFS-DNN을 제안한다. NSL-KDD 데이터 셋을 통해 학습을 진행하였으며, 기존 분류 모델들과 성능 비교를 수행한다. 본 연구에서 제안된 Hybrid Feature Selection 알고리즘이 학습 모델의 성능을 왜곡 시키지 않는 것을 확인하였으며, 불균형을 해소한 학습 모델들간 실험에서 본 논문에서 제안한 학습 모델이 가장 좋은 성능을 보였다.