• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.76.1-76.1
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• 2012

We have employed SNANA supernova analysis package to make YONSEI Supernova Catalogue 1, which contains distance modulus, light-curve shape parameters, and color or extinction values of each supernova. This database is used to study the dependence of Type Ia supernovae (SNe Ia) luminosities on the host-galaxy morphologies. The redshift range of this catalogue is 0.010 < z < 1.555, and we use three light-curve fitters: SALT2, MLCS2k2 (Rv = 3.1), and MLCS2k2 (Rv = 1.7). We find a systematic difference in the Hubble residual (HR) of $0.1{\pm}0.031$ mag between E-S0 and Scd/Sd/Irr host-galaxies, and of $0.16{\pm}0.044$ mag between passive and star-burst host-galaxies. This difference is significant over the $3{\sigma}$ level. Considering the significant difference in the mean age of stellar population between these morphological types, the difference in the HR reported here suggests that the evolution effect of SNe Ia luminosity should be considered in the cosmological application of SNe Ia data.

• Nutrition Research and Practice
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• v.6 no.4
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• pp.286-293
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• 2012

Resveratrol (3,4,5-trihydroxy-trans-stilbene), a phytoalexin found in grape skin, grape products, and peanuts as well as red wine, has been reported to have various biological and pharmacological properties. The purpose of this study was to investigate the anti-obesity effect of resveratrol-amplified grape skin extracts on adipocytes. The anti-obesity effects of grape skin extracts were investigated by measuring proliferation and differentiation in 3T3-L1 cells. The effect of grape skin ethanol extracts on cell proliferation was detected by the MTS assay. The morphological changes and degree of adipogenesis of preadipocyte 3T3-L1 cells were measured by Oil Red-O staining assay. Treatment with extracts of resveratrol-amplified grape skin decreased lipid accumulation and glycerol-3-phosphate dehydrogenase activity without affecting 3T3-L1 cell viability. Grape skin extract treatment resulted in significantly attenuated expression of key adipogenic transcription factors, including peroxisome proliferator-activated receptor, CCAAT/enhancer-binding proteins, and their target genes (FAS, aP2, SCD-1, and LPL). These results indicate that resveratrol-amplified grape skin extracts may be useful for preventing obesity by regulating lipid metabolism.

• The Journal of Korean Medicine
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• v.36 no.4
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• pp.74-79
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• 2015

Objectives: Here we investigated the anti-lipogenic potential of kaurenoic acid (KA), a diterpene derived from Aralia continentalis, in a cellular model of non-alcoholic fatty liver disease. Methods: HepG2 cells were treated with palmitate for 24h to induce intracellular lipid accumulation. To assess the influence of KA on steatotic HepG2 cells, various concentration of KA was co-administered. After palmitate treatment, Intracellular triglyceride content was measured. Expression level of several lipogenic genes, sterol regulatory element-binding transcription factor-1c (SREBP-1c), acetyl-CoA carboxylase (ACC), fatty acid synthase (FAS), and stearoyl-CoA desaturase-1 (SCD-1) were measured using Western-blot analyses or RT-PCR. Results: Palmitate markedly increased intracellular triglyceride level and expression of related lipogenic genes in HepG2 cells, and which was relieved by co-administered KA. Conclusions: It is conceivable that that KA may have a pharmacological potential to reduce lipid accumulation in non-alcoholic fatty liver disease.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.32 no.1D
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• pp.51-59
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• 2012

An efficient application method of XML schema matching technique to the document structure of structural calculation document (SCD) of bridge is proposed. With 30 case studies, a parametric study on weightings of name, sibling, child, and parent elements of XML scheme component that are used in the similarity measure of XML schema matching technique has been performed, and suitable weighting to analyze document structure of SCD is suggested. A simplified formula for quantification of similarity is also introduced to reduce computation time in huge scale document structure of SCDs. Numerical experiments show that the suggested method can increase the accuracy of XML schema matching by 10% with suitable weighting parameters, and can maintain almost the same accuracy without weighting parameters compared to previous studies. In addition, computation time can be reduced dramatically when the proposed simplified formula for the quantification of similarity is used. In the numerical experiments of testing 20 practical SCDs of bridges, the suggested method is superior to previous studies in the accuracy of analyzing document structure and 4 to 460 times faster than the previous results in computation time.

• Korean Journal of Food Science and Technology
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• v.44 no.1
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• pp.69-75
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• 2012

To investigate the effects of soybean germination time on the quality of cheonggukjang, the physicochemical characteristics and enzyme activities of cheonggukjang during fermentation were compared. B. subtilis SCD 115035 strain isolated from traditional cheonggukjang was selected for making cheonggukjang. Germinated (12-h) soybeancheonggukjang produced the highest amount of viscous substance (13.22%) after 48 h of fermentation, and the contents were inversely proportional to the germination time of the soybeans. The acidic- and neutral-protease activities of ungerminated soybean-cheonggukjang were higher than those of germinated soybean-cheonggukjang. The amino nitrogen content of ungerminated soybean-cheonggukjang was the highest (436.93 mg%) at 48 h of fermentation, and its content was similar to that of 12-h germinated soybean-cheonggukjang. However, the total isoflavone content of 36-h germinated soybean-cheonggukjang was the highest after 72 h of fermentation, and its content was higher than those of cheonggukjang made from soybeans germinated for 0, 12, and 24 h.

• Journal of Environmental Science International
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• v.18 no.1
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• pp.1-7
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• 2009

In this study a sediment yield is compared by IUSG, IUSG with Kalman filter, tank model and tank model with Kalman filter separately. The IUSG is the distribution of sediment from an instantaneous burst of rainfall producing one unit of runoff. The IUSG, defined as a product of the sediment concentration distribution (SCD) and the instantaneous unit hydrograph (IUH), is known to depend on the characteristics of the effective rainfall. In the IUSG with Kalman filter, the state vector of the watershed sediment yield system is constituted by the IUSG. The initial values of the state vector are assumed as the average of the IUSG values and the initial sediment yield estimated from the average IUSG. A tank model consisting of three tanks was developed for prediction of sediment yield. The sediment yield of each tank was computed by multiplying the total sediment yield by the sediment yield coefficients; the yield was obtained by the product of the runoff of each tank and the sediment concentration in the tank. A tank model with Kalman filter is developed for prediction of sediment yield. The state vector of the system model represents the parameters of the tank model. The initial values of the state vector were estimated by trial and error.

• BMB Reports
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• v.46 no.4
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• pp.207-212
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• 2013

The main purpose of this study is to examine the effect of caffeine on lipid accumulation in human hepatoma HepG2 cells. Significant decreases in the accumulation of hepatic lipids, such as triglyceride (TG), and cholesterol were observed when HepG2 cells were treated with caffeine as indicated. Caffeine decreased the mRNA level of lipogenesis-associated genes (SREBP1c, SREBP2, FAS, SCD1, HMGR and LDLR). In contrast, mRNA level of CD36, which is responsible for lipid uptake and catabolism, was increased. Next, the effect of caffeine on AMP-activated protein kinase (AMPK) signaling pathway was examined. Phosphorylation of AMPK and acetyl-CoA carboxylase were evidently increased when the cells were treated with caffeine as indicated for 24 h. These effects were all reversed in the presence of compound C, an AMPK inhibitor. In summary, these data indicate that caffeine effectively depleted TG and cholesterol levels by inhibition of lipogenesis and stimulation of lipolysis through modulating AMPK-SREBP signaling pathways.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.43 no.1 s.307
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• pp.55-66
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• 2006

We propose a progressive image retrieval method based on an efficient combination of multiresolution color and torture features in wavelet transform domain. As a color feature, color autocorrelogram of the hue and saturation components is chosen. As texture features, BDIP and BVLC moments of the value component are chosen. For the selected features, we obtain multiresolution feature vectors which are extracted from all decomposition levels in wavelet domain. The multiresolution feature vectors of the color and texture features are efficiently combined by the normalization depending on their dimensions and standard deviation vector, respectively, vector components of the features are efficiently quantized in consideration of their storage space, and computational complexity in similarity computation is reduced by using progressive retrieval strategy. Experimental results show that the proposed method yields average $15\%$ better performance in precision vs. recall and average 0.2 in ANMRR than the methods using color histogram color autocorrelogram SCD, CSD, wavelet moments, EHD, BDIP and BVLC moments, and combination of color histogram and wavelet moments, respectively. Specially, the proposed method shows an excellent performance over the other methods in image DBs contained images of various resolutions.

• Korean Journal of Remote Sensing
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• v.22 no.2
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• pp.141-151
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• 2006

UV-visible absorption measurement techniques using several horizone viewing directions in addition to the traditional zenith-sky pointing have been recently developed in ground-based remote sensing of atmospheric constituents. The spatial distribution of various trace gases close to the instrument can be derived by combing several viewing directions. Multi-axis differential optical absorption spectroscopy (MAX-DOAS) technique, one of the remote sensing techniques for air quality measurements, uses the scattered sunlight as a light source and measures it at various elevation angles (corresponding to the viewing directions) by sequential scanning with a stepper motor. A MAX-DOAS system developed by GIST/ADEMRC has been applied to measuring trace gases in urban air and plumes of the volcano and fossil fuel power plant in January, May, and October 2004, respectively. MAX-DOAS spectra were analyzed to identify and quantify $SO_2,\;NO_2,\;BrO,\;and\;O_4$ (based on Slant Column Densities, SCD) in the urban air, volcanic plume, and fossil fuel power plant utilizing theirs specific structured absorption features in the UV-visible region. Vertical scan through the multiple elevation angles was performed at different directions perpendicular to the plume dispersion to retrieve cross-sectional distribution of $SO_2\;or\;NO_2$ in the plumes of the volcano and fossil fuel power plant. Based on the estimated cross sections of the plumes the mixing ratios were estimated to 580 $SO_2$ ppbv in the volcanic Plume, and 337 $NO_2\;and\;227\;SO_2$ ppbv in the plume of the fossil fuel power plant, respectively.

• Ocean and Polar Research
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• v.44 no.1
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• pp.61-67
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• 2022

In this study, in order to evaluate the anti-obesity effect of sargassum horneri extract, the effects of the extract on lipase activity and preadipocyte differentiation in 3T3-L1 cells were investigated. S. horneri extract between 0.0 and 1.0 mg/mL showed no cytotoxicity and inhibited lipase activity by 68.1%. When S. horneri extract was utilized at levels of 0.25, 0.5, and 1.0 mg/mL in 3T3-L1 cells, preadipocytes differentiation decreased by 11.4, 19.7, and 25.6%, respectively, showing anti-obesity effects. In addition, after treatment with 1.0 mg/mL S. horneri extract, the mRNA expression levels of sterol regulatory element binding proteins-1c (SREBP-1c), peroxisome proliferator activated receptor-γ (PPAR-γ), CCAAT enhancer binding protein-α (CEBP-α), fatty acid synthase (FAS), and stearoyl-CoA desaturase1 (SCD1) in 3T3-L1 cells were significantly decreased (p < 0.05) by 65.2, 54.9, 50.0, 33.8, and 33.8% respectively. These results showed that S. horneri extract suppresses lipase activity and prophylactic preadipocyte differentiation in 3T3-L1, and thus can be used as an anti-obesity agent in functional foods and medicines.