• 사상체질의학회지
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• 제35권3호
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• pp.12-28
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• 2023

Introduction This study reports case series of Soyangin patients with coldness in hands and feet using Sasang constitutional medicine approach. This study suggests a value of using constitutional medicine indicators as both prognostic and diagnostic tools. Methods Among patients who visited an outpatient clinic, 7 patients were selected based on the criteria. These selected patients were exclusively treated with herbal medicine and monitored every 2 to 4 weeks retrospectively. Results The average treatment period was 8 weeks. Patients with a favorable pattern showed the improvement within 8 weeks, while those with an unfavorable pattern required more time. Discussion This study confirms the significance of Sasang constitutional medicine approach in Soyangin exterior cold syndrome with coldness in hands and feet. It also validates the current coldness in hands and feet as meaningful diagnostic indicator of Soyangin exterior cold syndrome. Furthermore, it highlights the value of original symptoms as prognostic tools.

• 동의생리병리학회지
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• 제19권2호
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• pp.530-535
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• 2005

A Korean traditional herbal formular, Taeumbiman-tang(TBT), was based on Taeumjowi-tang, currently the most widely used herbal formula compound, and which is known to be safe and have a positive effect on adult obesity. TBT was given to obese children for thirty days, and was found to be clinically safe and effective. The subjects were children who had been admitted into the hospital to be treated for obesity, that had more than 20% relative body weight. Originally there were 19 subjects, but 5 dropped out of the experiment. There were 5 girls and 9 boys, whose average ages were $11.00\;{\pm}\;2.60$ years, average weight was $54.01\;{\pm}\;18.59\;kg$. As a pretest, all of the volunteers were examined for height, weight, blood pressure, pulse rate, EKG, and chest radiography. The subjects underwent interview, body measurement tests, blood tests, and safety tests under 8 hour fasting state. After 15 days of TBT intake, the safety tests and the interview were conducted. The interview, body measurement tests, blood tests, and safety tests were conducted again after the 30 day trial was completed. The short term effects of TBT on obese children is weight loss. It did not cause any significant changes in the subject's livers, hearts, and kidneys, and clinically dangerous side effects or withdrawal symptoms were not observed.

• 사상체질의학회지
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• 제25권3호
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• pp.158-166
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• 2013

Objectives Recently, Sasang Constitutional Analysis Tool (SCAT) was developed using face, body shape, questionnaire, and voice information. The purpose of this paper is to analysis the characteristics of SCAT in detail for the subjects whose Sasang Constitutional (SC) type was confirmed clearly. Methods 1) The SC types of 108 patients were diagnosed by an expert of Sasang constitutional medicine through the observation of improvements after taking more than 20 packs of herbal medicine prescribed 2) The diagnostic results of SCAT were acquired for the patients. 3) Comparison between diagnostic results of the SCAT and expert was performed according to SC probability difference, the number of packs of herbal medicine prescribed, the number of hospital visits, and age. Results 1) The concordance rate was 65.9% and 59.4% in the male and female groups, respectively. 2) Overall, the concordance rate increased as the SC probability difference increased. In case of more than 5% SC probability difference, it increased up to 71.0% and 66.7% in the male and female groups, respectively. 3) The concordance rate did not show any trend as the number of packs of herbal medicine prescribed and the number of hospital visits increased. 4) The higher concordance rate was observed in Taeeumin, Soyangin, and 20s ~ 40s groups of male patients, and in Soyangin, 20s, and 40s groups of female patients. Conclusions The strong and weak points of SCAT were observed and they will contribute to the improvement of SCAT performance.

• 사상체질의학회지
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• 제21권3호
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• pp.154-167
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• 2009

1. Objectives: Fever is an abnormal elevation of body temperature, usually as a result of a pathologic process. Fever can cause chilling, myalgia, headache and other related symptoms. We have tried researching effect of herbal medicine Doksampalmulkunja-tang(獨蔘八物君子湯) on fever. 2. Methods: The subjects are three patients who were on diagnosed Soeumin Woolgwang-incurable disease. They are treated by Doksampalmulkunja-tang(獨蔘八物君子湯). 3. Results: Doksampalmulkunja-tang(獨蔘八物君子湯) was effective on the subjects. Their fever and related symptoms were improved. 4. Conclusions: This case study shows that the treatment with herb-medicine may have effect on fever of Soeumin by rasing the stagnant yang qi.

• 사상체질의학회지
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• 제28권1호
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• pp.57-66
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• 2016

Objectives The purpose of this study is to report on the collecting status of the prospective clinical data, that is designed to find clinical factors for determining the constitutional prescription.Methods We collected the prospective clinical data of 1208 subjects in the 10 oriental hospitals and 2 oriental clinic, from September 2012 to July 2015. Subjects were diagnosed and prescribed by the Sasang Constitution specialist. We counted the usage frequency of each constitutional herbal formula. Besides we check the main chief complaints on each constitutional herbal formula.Results & Conclusions In TE type, Yeoldahanso-tang, Cheongsimnyeonja-tang were used in high frequency. In SE type, Palmulgunja-tang, Gwakhyangjunggi-san were used in high frequency. In SY type, Hyeongbangjihwang-tang, Yanggyeoksanhwa-tang were used in high frequency. The both of high frequency-prescriptions in TE types were for the Interiorheat disease, expecially liver-heat lung-dry symptomatology. The main chief complaint of high frequency-prescriptions was fatigue in every constitution. We hope that the process of constitutional prescription would be standardized through the subsequent researches.

• 사상체질의학회지
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• 제25권4호
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• pp.373-383
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• 2013

Objectives The purpose of this clinical trial was evaluate the safety and efficacy of Mahwangjeongcheon-tang (MJT). Methods Twenty six volunteers were recruited as subjects. They were divided into two groups, which were MJT test group and placebo group. The investigated items related to the safety were the weight, the results of renal function and liver function. The investigated items related to the efficacy are the results of the spirometer, the clinical asthma measurement scale in oriental medicine-V (CAMSOM-V) and the quality of life questionnaire for adult Korean asthmatics (QLQAKA). Results There are no difference in the weight, the results of the renal functions and the liver functions between MJT test group and placebo group. There are the some differences in the result of the questionnaires related to the efficacy between MJT test group and placebo group. The significant difference were observed in the CAMSOM-V at the 4th visit. Conclusion MJT is the safe and effective herbal prescription that is useful to the asthma patients.

• 사상체질의학회지
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• 제14권3호
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• pp.85-96
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• 2002

The purpose of this study is to examine the effects of sasang constitutional herbal extracts such as Yangkyuksanhwatang(YST) on EKG. For this purpose, 3 hospitalized Soyangin patients having heart disease history was selected. and changes of the symptoms and EKGs was investigated. We measured and observed EKG changes of before YST medication and after medication. The results of these experiments were as follows. 1. The activity of HR, PR, QRS was decreased on EKG2 comparison to EKG1 after Yangkyuksanhwatang(YST) medication 2. QT, QTC interval was prolonged after YST medication 3. RR time was prolonged after YST medication 4. The voltage of Q wave was decreased after YST medication From the above results, it is suggested that Yangkyuksanhwatang(YST) have influenced on EKG.

• 사상체질의학회지
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• 제24권4호
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• pp.75-83
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• 2012

Objectives : Although Yeoldahanso-tang (YDHST) has been widely used for treatment of obesity and its related diseases such as hyperinsulinemia and hypertension for Taeeumin, no scientific evidence has reported yet to support its ability to work against these metabolic disorders. Our study was aimed to investigate the anti-obesity effect of YDHST extract on the cellular differentiation of 3T3-L1 preadipocytes into adipocytes. Methods : 3T3-L1 preadipocytes were differentiated into adipocytes by adding insulin, dexamethasone and 3-isobutyl-1-methylxanthine (IBMX) for 8 days in the absence or presence of YDHST extract. Anti-obesity effects of YDHST extract were evaluated by Oil Red O staining, glycerol-3-phosphate dehydrogenase (GPDH) activity, triglyceride contents, and leptin production. Results : YDHST extract remarkably prevented lipid accumulation with no cytotoxicity in the differentiated 3T3-L1 cells. In addition, YDHST extract decreased contents of triglyceride 3T3-L1 adipocytes. Consistently, YDHST extract caused a significant inhibition of GPDH activity and leptin production in a dose-dependent manner. Conclusions : Our findings suggest that Sasang constitutional herbal formula YDHST for Tae-eumin has anti-obesity activity by regulation of the adipogenesis process in vitro. Additional study will be required to further confirm the inhibitory effect on adipocyte differentiation by using in vivo animal model.

• 한국한의학연구원논문집
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• 제14권1호
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• pp.91-96
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• 2008

Although the theory of Sasang Consititution is widely used in oriental clinic, there is only conceptual definition about the constitution not technical definition which is consented by every experts. In the present, the effect and different responses of constitutional medicines is the most widely accepted criteria among technical definitions. However, these medicines consist of several herbs which are included specific constitution. So, it is hard to define the characters about the Sasang Constitution through analysis of the medicines. In this paper, we collected the various information about the constitutional herbs, and constructed database and web application for accessing this information. It is useful and can be basis for finding the characteristics of constitutional medicines.

• 사상체질의학회지
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• 제15권2호
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• pp.89-93
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• 2003

Pernicious anemia is a pathologic state due to lack of Vit.B12 or folic acid. Pernicious anemia is due to metabolic disorder including poor absorption of stomach through gastroectomy. We experienced a 76 year old male patient diagnosed as pernicious anemia for perfomed total gastroectomy. Herbal medicine that we had was mainly treated and several remarkable changes have been showed. This is a clinical report of that patient.