• Proceedings of the Korean Society of Precision Engineering Conference
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• 2012.10a
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• pp.983-984
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• 2012

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2011.06a
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• pp.47-48
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• 2011

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2010.11a
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• pp.303-304
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• 2010

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.309-313
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• 2018

Maker Activity based Design-Thinking 5 Step is a better experience for providing the public with a better approach to design by sympathizing with human needs and exploring the public's potential desires. This paper studied the teaching method by applying the value of the Maker Training that emphasizes the importance of sharing and opening results with others after creating them based on the ideas of the learners using different tools, the basic mind of Design-Thinking with the observation and empathy about human beings and the derivation of user-centric results to the SW coding curriculum. For this purpose, we studied teaching methods by Design-thinking based on sections that require coding in the information classes of the secondary school curriculum. We demonstrated the class to a group of education experts by applying the syllabus of instruction. Then we collected evaluations and opinions of the experts and we modified the syllabus to reflect the collected assessment. Under the Design-thinking 5 step foundation, classes were demonstrated with a group of education experts, opinions collected, and suggestions collected were reflected on the assessment outcome. I think that It is an effective training opportunity to practice a widespread idea that enables infinite thinking and a convergence of thinking that brings out the best decision from a widespread idea.

• Journal of KIISE
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• v.41 no.11
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• pp.935-942
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• 2014

Today, it is very important issue to high quality of software issue on huge scale of code and time-to-market. In the industrial fields still developers focuses on Code based development. Therefore we try to consider two points of views 1) improving the general developer the bad development habit, and 2) maintenance without design, documentation and code visualization. To solve these problems, we need to make the code visualization of code. In this paper, we suggest how to visualize the inner structure of code, and also how to proceed improvement of quality with constructing the Tool-Chain for visualizing Java code's inner structure. For our practical case, we applied Object Code with NIPA's SW Visualization, and then reduced code complexity through quantitatively analyzing and visualizing code based on setting the basic module unit, the class of object oriented code.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2473-2481
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• 2015

Colon cancer is one of the leading causes of cancer-associated death worldwide. The prognosis for advanced colorectal cancers remains dismal, mainly due to the propensity for metastatic progression. Accordingly, there is a need for effective anti-metastasis therapeutic agents. Since a great body of research has indicated anticancer effects for curcumin, we investigated the effects of dendrosomal curcumin (DNC) on cellular migration and adhesion of human SW480 cells and possible molecular mechanisms involved. Different methods were applied in this study including MTT, Scratch and adhesion assays as well as real-time PCR and transwell chamber assays. Based on the results obtained, DNC inhibits metastasis by decreasing Hef 1, Zeb 1 and Claudin 1 mRNA levels and can reduce SW480 cell proliferation with $IC_{50}$values of 15.9, 11.6 and $7.64{\mu}M$ at 24, 48 and 72h post-treatment. Thus it might be considered as a safe formulation for therapeutic purpose in colorectal cancer cases.

• BMB Reports
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• v.49 no.4
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• pp.220-225
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• 2016

Cancer cells have different characteristics due to the genetic differences where these unique features may strongly influence the effectiveness of therapeutic interventions. Here, we show that the spontaneous reactivation of extracellular signalregulated kinase (ERK), distinct from conventional ERK activation, represents a potent mechanism for cancer cell survival. We studied ERK1/2 activation in vitro in SW480 colorectal cancer cells. Although ERK signaling tends to be transiently activated, we observed the delayed reactivation of ERK1/2 in epidermal growth factor (EGF)-stimulated SW480 cells. This effect was observed even after EGF withdrawal. While phosphorylated ERK1/2 translocated into the nucleus following its primary activation, it remained in the cytoplasm during late-phase activation. The inhibition of primary ERK1/2 activation or protein trafficking, blocked reactivation and concurrently increased caspase 3 activity. Our results suggest that the biphasic activation of ERK1/2 plays a role in cancer cell survival; thus, regulation of ERK1/2 activation may improve the efficacy of cancer therapies that target ERK signaling.

• Journal of Advanced Navigation Technology
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• v.18 no.1
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• pp.22-28
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• 2014

This paper presents the design and development of ECU simulator in order to verify automatic firmware update system of ECU SW on the vehicle. We designed and developed general-proposed ECU simulator as devide into HW and SW parts. HWadopt 32bit MPU, CAN, LIN, LCD, and touch-pad button to satisfy general-proposed ECU level. And SW constructed as finite-state-machine structure in order to support HW spec. We developed ECU manager which deliveries update data to verify validity of operation. And we tested ECU simulator with ECU manager. For test of validity of ECU simulator, we set 4 scenarios between ECU simulator and manager. As the result, we confirmed validity of operation in ECU simulator for automatic SW update system.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.05a
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• pp.756-759
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• 2015

As the struggle to get a job becomes increasingly ferocious year after year, the website offering a range of employment information have continued to gain popularity. Those website, however, are not of much help when it comes to an interview to face the interviewer. Furthermore, many people suffer depression due to the heavy stress they are under while making preparations for employment or working for an organization. The current employment website do not have a team of professionals to deal with such issues. In an effort to solve those problems, the present study made arrangements to allow users to put in an enormous amount of employment information based on Google App Engine(GAE) and Google Web Toolkit(GWT) and upload interview videos. In addition, a Q&A board was created to help those who prepare for employment or current workers relieve their stress and provide them with access to a team of counseling professionals.

• Korean Chemical Engineering Research
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• v.52 no.1
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• pp.119-125
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• 2014

This study evaluated the environmental impacts of a soil washing (SW) process, especially, we compared the on-site and off-site remediation of TPH-contaminated soil using green and sustainable remediation (GSR) tool. To assess relative contribution of each stage on environmental footprints in the entire soil washing process, we classified the process into four major stages: site foundation (stage I), excavation (stage II), separation & washing (stage III), and wastewater treatment (stage IV). In on-site SW process, the relative contribution of $CO_2$ emissions and energy consumption were 87.1% and 80.4%, respectively in stage I, and in off-site SW process, the relative contribution of $CO_2$ emissions and energy consumption were 82.7% and 80.5%, respectively in stage II. In conclusion, the major factor contributing environmental impact in the SW process were consumable materials including steel and stainless steel for washing equipment in on-site treatment and fuel consumption for transportation of soil in off-site treatment.