• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1727-1735
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• 2012

Regardless of advances in treatment modalities with the invention of newer therapies, breast cancer remains a major health problem with respect to its diagnosis, treatment and management. This female malignancy with its tremendous heterogeneous nature is linked to high incidence and mortality rates, especially in developing region of the world. It is the malignancy composed of distinct biological subtypes with diverse clinical, pathological, molecular and genetic features as well as different therapeutic responsiveness and outcomes. This inconsistency can be partially overcome by finding novel molecular markers with biological significance. In recent years, newer technologies help us to indentify distinct biomarkers and increase our understanding of the molecular basis of breast cancer. However, certain issues need to be resolved that limit the application of gene expression profiling to current clinical practice. Despite the complex nature of gene expression patterns of cDNAs in microarrays, there are some innovative regulatory molecules and functional pathways that allow us to predict breast cancer behavior in the clinic and provide new targets for breast cancer treatment. This review describes the landscape of different molecular markers with particular spotlight on vitamin D signaling pathway and apoptotic specific protein of p53 (ASPP) family members in breast cancer.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.62
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• pp.55-86
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• 2014

Korea has become a member of the United Nations Convention on Contract of the International Sales of Goods (the 'CISG') effective since March 1, 2005. As, therefore, the governing law of the general terms and conditions (the 'GTC') in the Government Foreign Procurement Contract (the 'Contract') is mandatorily fixed to the Korean Law, the CISG, as an International Convention, now having an equivalent or even higher status to the Korean Law, unless expressly excluded, will be priorly applied to the Contract where a transaction occurs between its members. In this regard, this study focuses on how to find the way for the CISG to be a governing law of the GTC in order to eliminate legal uncertainties and lacks of foreseeability prevailed in the international trade. For that purpose, the legal aspects of GTC, and the Buyer's remedy for the Seller's breach of the Contract are analyzed in accordance with the comparative study between the CISG and the GTC including the relevant case studies. As a result of this study, the application of the CISG into the GTC is highly recommended in order to reflect into the Contract such features as fairly harmonized for the interest of both parties. Taking this opportunity, a GTC, amended from the existing one, or newly formed, within the perimeter of not conflicting with the provisions of the CISG, including but not limited to the Civil Law and Commercial Law, is required in order to evenly share each party's responsibilities and obligations where the breach or remedy of the Contract is, and, thus, which will ultimately contribute to an efficient conduct of the Contract.

• Journal of KIISE:Software and Applications
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• v.37 no.12
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• pp.946-950
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• 2010

Many sentiment categorization systems based on machine learning methods use morphological analyzers in order to extract linguistic features from sentences. However, the morphological analyzers do not generally perform well in a customer review domain because online customer reviews include many spacing errors and spelling errors. These low performances of the underlying systems lead to performance decreases of the sentiment categorization systems. To resolve this problem, we propose a feature extraction method based on simple longest matching of Eojeol (a Korean spacing unit) and phoneme patterns. The two kinds of patterns are automatically constructed from a large amount of POS (part-of-speech) tagged corpus. Eojeol patterns consist of Eojeols including content words such as nouns and verbs. Phoneme patterns consist of leading consonant and vowel pairs of predicate words such as verbs and adjectives because spelling errors seldom occur in leading consonants and vowels. To evaluate the proposed method, we implemented a sentiment categorization system using a SVM (Support Vector Machine) as a machine learner. In the experiment with Korean customer reviews, the sentiment categorization system using the proposed method outperformed that using a morphological analyzer as a feature extractor.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.20 no.4
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• pp.383-387
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• 1998

The mucoepidermoid carcinoma is classified as either well, moderately, or poorly differentiated. The criteria used to classify the lesions are discussed, and pathologic features are illustrated. The most important factors in prognosis are : 1. degree of histologic differentiation, and 2. presence or abscence of tumor on the lines of surgical excision. Recurrences rates are correlated with histologic differentiation. Stewart, Foote, and Becker in 1945 coined the term "mucoepidermoid tumor" to discribe an unusual salivary neoplasm containing epidermoid and mucus-secreting cells which was thought to arise in salivsary gland ducts. The treatment of the mucoepidermoid carcinoma is chiefly surgical, although recent data have shown favorable responses to radiation therapy. Currently, surgery followed by radiation treatment is recommended for intermediate-grade and high-grade tumors ; low-grade tumors can be managed by surgery alone. Authors present a case of mucoepidermoid carcinoma managed with wide surgical resection and postoperative irradiation and showing a good clinical result with review of literatures.

• Journal of Oral Medicine and Pain
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• v.42 no.4
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• pp.89-101
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• 2017

Purpose: The purpose of this study is to investigate the prevalence of temporomandibular disorders (TMDs) in children and adolescents, their characteristic contributing factors, the characteristic features of symptoms and symptoms, and the response to treatment. Methods: We studied the researches, that were the results of the searches for words such as temporomandibular disorder, TMD, children, adolescents, and juvenile through PubMed and DBpia. Results: According to a study conducted in Busan, the ratio of adolescents increased from 18.3% to 21% in 2008 compared to 2000, and the proportion of boys increased from 38.58% to 45.38%. One of the characteristic contributing factors for adolescents is the macrotrauma such as jaw trauma, vehicle accidents, sports, physical abuse, forceful intubation, and third molar extraction. The second is a microtrauma from parafunctional habit such as bruxism, clenching, hyperextension, wind instrument, and fingernail biting that can cause joint overload, cartilage breakdown, synovial fluid alterations, and other changes within the joint. The diagnosis of TMDs in juvenile adolescents is not significantly different from that of adults. Medical history, clinical examination and radiological examinations are required. Conclusions: In the temporomandibular joint history and assessment, all comprehensive dental history examination is required, including head and neck pain, mandibular dysfunction, previous orofacial trauma, history of present illness with an account of current symptoms. For the treatment and management of temporomandibular arthritis in juvenile adolescents, understanding the characteristics of TMDs in juvenile adolescents and thoroughly analyzing appropriate diagnosis and possible contributing factors through comprehensive history taking & examination, conservative treatment, including fast and active cautions education, will be essential.

• Biomedical Science Letters
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• v.3 no.1
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• pp.43-47
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• 1997

The authors presented the human Thelaziasis case in Korea, with the review of the literatures. The patient was 60-year-old farmer who had lived in Chunchoun since birth. He complained lacrimation and foreign body sensation of the left eye. Total 10 worms, appeared to be slender milky-white nematodes, were extracted from the left upper conjuctival sac by authors. Micrograph morphological features are as follows： Three male worms are 8.83∼9.32 mm in length, 0.24∼0.25 mm in width, 259∼263 cuticular striations per mm, and showing cloaca with spicules. seven female worms are 11.91∼12.77 mm in length, 0.25∼0.26 mm in width, 259∼289 cuticular striations per mm, and vulva opening locating anterior to esophago-intestinal junction. From the above findings, these nematodes were confirmed as Thelazia callipaeda Railliet and Henry, 1910.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.10 no.5
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• pp.63-71
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• 2015

Lean six sigma has to be utilized considering irrational system or defects based on features of organization beforehand. Otherwise, it won't improve anything but burden another heavy responsibilities to the people in charge. Therefore, a survey was conducted in addition to a literature review and a case study about lean six sigma to verify effective deployment method for lean 6sigma tools. The survey was conducted across for 96 interviewees who have MBB or BB was selected from 15 companies which have been running six sigma projects over 10 years and SPSS 16.0 was used for verifying reliability and validity of the research. In conclusion, some issues occurred in the process of six sigma projects were identified and effective deployment method of lean six sigma tools by integrating lean manufacturing into 6sigma were suggested based on those issues.

• Journal of the Korean Society of Costume
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• v.51 no.1
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• pp.163-174
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• 2001

The purpose of this study is to review the features of eroticism expressed in men's fashion, to explain psychological and social contexts which engender eroticism and to analyze in what way eroticism is portrayed in men s fashion in this context. Eroticism as the metonymy of forbidden sexual desire, has been embodied mostly in visual forms such as picture and photo. From a psychoanalytic view, the context in which eroticism is formed can be explained by primary narcissism and fetishism. Primary narcissism is the feeling of satisfaction with the self in which the subject who is admiring and the object of admiration are one and the same. Accordingly, in order to give rise to eroticism, both subject and object have to exist. Fetishism, the metonymy of castrated penis, is also one of the factors to produce eroticism. Metaphorically seen as a woman who has a penis, a man who dresses in the same manner as a woman dresses can be a source of eroticism to gays. From a sociological view, the context in which eroticism is fostered depends on the dynamic relations among social powers. In these relations, who is a subject or who is an object has been continuously changing. In the Post-modern culture appearing in the late 20th century, power begins to take various forms, and gays and women who had never been subjects begin to make man an object of eroticism. The other point is that social morality, ignoring desire itself, objectifies sexual desire and seeks to remove It by exchanging it for objectified symbols. The design elements provoking eroticism in men s fashion are exposure and decoration. In particular, models in exposure and decorative fashion have been objectified through the methods of fragmentation rather than showing the whole figure or removing a person s individuality or will,.

• The Journal of the Korea Contents Association
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• v.11 no.11
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• pp.91-101
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• 2011

This research aims to suggest web-based 3D face modeling system for hairline modification surgery. As public interests in beauty regarding face escalate with era of wide persoanl mobile smart iCT devices, need for medical information system is urgent and increasing demand. This research attempted to build 3D facing modeling library deploying conventional technology and proprietary software available. Implications from the our experiment found that problems and requirement for developing new web based standard. We suggest new system from our experiment and literature review regarding relevant technologies. Main features of our suggested systems is based on studies regarding hair loss treatment such as medical science, beauty studies and information technology. This system processes input images of 2D frontal and profile pictures of face into 3D face modeling with mesh-data. The mesh data is compatible with web standard technology including SVG and Canvas Tag supported natively by HTML5.

• Journal of Dairy Science and Biotechnology
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• v.30 no.2
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• pp.119-129
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• 2012

Lactic acid bacteria (LAB) have been used as starter cultures in the manufacturing processes of fermented dairy products such as cheese and yogurt. LAB have a proteolytic system to use the nitrogen source from milk for their growth. The proteolytic system involved in casein utilization provides cells with essential amino acids during growth in milk and is also of industrial importance, because of its contribution to the development of the organoleptic properties such as flavor of fermented milk products. In the most extensively studied LAB, Lactococcus lactis, the main features of the proteolytic system comprise 3 groups. The first is proteinase, which initially cleaves the milk protein to peptides. The second group consists of transport systems for the internalization of oligopeptides, which are involved in the cellular uptake of small peptides and amino acids. The third group, peptidases in the cell, cleaves peptides into smaller peptides and amino acids. This review is to provide the information about the proteolytic system of LAB.