• 제목/요약/키워드: Research and Development Department

검색결과 20,363건 처리시간 0.054초

신형식 해상풍력 구조체 최적 설계 (Optimum Design of New Type Offshore Wind Power Tower Structure)

  • 한택희;윤길림;원덕희;오영민
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2012년도 춘계학술대회
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    • pp.388-389
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    • 2012
  • 현재 해상풍력 발전 타워는 강구조로 제작되고 있으며, 발전용량의 증가에 따라 타워 구조체 또한 장대화 되는 추세이다. 강조조물의 특성상 좌굴에 취약하며, 장대화 됨에 따라 세장비가 증가하여, 좌굴 및 진동에 취약한 특성을 보이게 된다. 본 연구에서는 신형식 구조체인 이중관-콘크리트 합성 구조(DSCT; Double Skinned Composite Tubular)를 적용한 해상풍력 타워를 제시하고 요구 성능을 만족하는 최적 단면 설계를 제시하였다. 관은 섬유보강 합성수지 (FRP; Fiber Reinforce Polymer)와 강재를 적용한 경우를 고려하였으며, 모두 요구 성능을 만족하였다.

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Applications of molecular markers in the discrimination of Panax species and Korean ginseng cultivars (Panax ginseng)

  • Jo, Ick Hyun;Kim, Young Chang;Kim, Dong Hwi;Kim, Kee Hong;Hyun, Tae Kyung;Ryu, Hojin;Bang, Kyong Hwan
    • Journal of Ginseng Research
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    • 제41권4호
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    • pp.444-449
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    • 2017
  • The development of molecular markers is one of the most useful methods for molecular breeding and marker-based molecular associated selections. Even though there is less information on the reference genome, molecular markers are indispensable tools for determination of genetic variation and identification of species with high levels of accuracy and reproducibility. The demand for molecular approaches for marker-based breeding and genetic discriminations in Panax species has greatly increased in recent times and has been successfully applied for various purposes. However, owing to the existence of diverse molecular techniques and differences in their principles and applications, there should be careful consideration while selecting appropriate marker types. In this review, we outline the recent status of different molecular marker applications in ginseng research and industrial fields. In addition, we discuss the basic principles, requirements, and advantages and disadvantages of the most widely used molecular markers, including restriction fragment length polymorphism, random amplified polymorphic DNA, sequence tag sites, simple sequence repeats, and single nucleotide polymorphisms.

Physiological Effects of Diethylstilbestrol Exposure on the Development of the Chicken Oviduct

  • Seo, Hee-Won;Park, Kyung-Je;Lee, Hyung-Chul;Kim, Dae-Yong;Song, Yong-Sang;Lim, Jeong-Mook;Song, Gwon-Hwa;Han, Jae-Yong
    • Journal of Animal Science and Technology
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    • 제51권6호
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    • pp.485-492
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    • 2009
  • Estrogen has dramatic effects on the development and function of the reproductive tract in mammals. Although diethylstilbestrol (DES) triggers the development of reproductive organs in immature animals, continued exposure to DES induces dysfunction of the female reproductive tract in mice. To investigate the effects of neonatal estrogen exposure on the reproductive tract of female chickens, we implanted DES pellets into the abdominal region of immature female chicks and then examined the effects of DES on the oviducts of both immature chicks and sexually mature chickens (30 weeks old). DES induced mass growth and differentiation of the oviduct in immature chicks. The chick oviduct increased by 2.7- and 29-fold in length and weight, respectively, following primary DES stimulation. In secondary DES stimulation, the length and weight of the chick oviduct increased by 4.5- and 74-fold, respectively. Additionally, DES treatments caused abnormal development of the infundibulum and magnum in hen oviducts. Furthermore, infundibulum abnormality gave rise to unusual ovulation of follicles and resulted in infertility and dysfunction of the magnum, such as less production of egg white proteins. Our results indicate that DES exposure during early developmental stages in chickens has detrimental effects on the development and maintenance of the female reproductive tract after sexual maturation.

Genetic Approach to Identify Critical Factors for Mouse Early Embryogenesis

  • Park, Joon-Hyun;Kim, Ji-Soo;Sonn, Sung-Keun;Rhee, Kun-Soo
    • Animal cells and systems
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    • 제10권1호
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    • pp.41-47
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    • 2006
  • Development of the mammalian pre-implantation embryos has unique features, such as a slow and unsynchronized cell division, compaction, and eventual formation of blastocysts with inner cell mass and trophectoderm. In order to have a clue on molecular mechanisms that reside in mouse early development, we suppressed expression of early embryo-specific genes with RNAi and observed their development in vitro. We observed developmental defects in embryos microinjected with dsRNAs for Oct4 or Nanog among the tested genes. Careful examinations revealed that development of the most of the Oct4- or Nanog-suppressed embryos were arrested at the morula stage. These results suggest that the Oct4 and Nanog activities are also required for embryogenesis earlier than the blastocyst stage.

Detection algorithm of ionospheric delay anomaly based on multi-reference stations for ionospheric scintillation

  • Yoo, Yun-Ja;Cho, Deuk-Jae;Park, Sang-Hyun;Shin, Mi-Young
    • 한국항해항만학회지
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    • 제35권9호
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    • pp.701-706
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    • 2011
  • Radio waves including GPS signals, various TV communications, and radio broadcasting can be disturbed by a strong solar storm, which may occur due to solar flares and produce an ionospheric delay anomaly in the ionosphere according to the change of total electron content. Electron density irregularities can cause deep signal fading, frequently known as ionospheric scintillation, which can result in the positioning error using GPS signal. This paper proposes a detection algorithm for the ionosphere delay anomaly during a solar storm by using multi-reference stations. Different TEC grid which has irregular electron density was applied above one reference station. Then the ionospheric delay in zenith direction applied different TEC will show comparatively large ionospheric zenith delay due to the electron irregularity. The ionospheric slant delay applied an elevation angle at reference station was analyzed to detect the ionospheric delay anomaly that can result in positioning error. A simulation test was implemented and a proposed detection algorithm using data logged by four reference stations was applied to detect the ionospheric delay anomaly compared to a criterion.

사염화탄소로 섬유화가 유도된 흰쥐 간에서 털부처꽃 뿌리 추출물의 항산화 및 섬유화저해 활성 (Antioxidant and Anti-fibrotic Properties of Root Extract of Lythrumsalicaria L. in $CCL_4$-Induced Liver Fibrosis Rat Model)

  • 이승은;안태진;김금숙;김영옥;한희선;서진숙;정해영;박충범;차선우;박호기;성낙술
    • 한국약용작물학회지
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    • 제17권4호
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    • pp.243-250
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    • 2009
  • Fifty percent ethanol extract of Lythrum salicaria Linne root (LSR) was tested in vitro on antioxidant activity, and furthermore was investigated on antioxidative and fibrosis protecting activities in $CCL_4$-induced liver fibrosis rat model. Ratio of hepatic GSH/GSSG (reduced glutathione/oxidized glutathione) as bio-parameter of antioxidant level in $CCL_4$ plus LSR-treated rats for 6 weeks significantly increased from 2.8- to 5.7-fold than that of $CCL_4$-treated rats at p < 0.05. Thiobarbituric acid reactive substances (TBARS) contents in $CCL_4$ plus LSR-treated rats ranged from 1.57- to 2.19-fold of normal rats and were lower than those in $CCL_4$ plus silymarin-treated rats ($1.78{\sim}2.46$-fold of normal rats) (p < 0.05). Amounts of hydroxyproline of liver tissue showing the content of total collagen, a parameter of fibrosis, in $CCL_4$ plus LSR-administrated rat livers were $4.9{\sim}8.8{\mu}g$/mg ($-47{\sim}-71%$, compared with that in $CCL_4$-treated rat livers ($16.6{\mu}g$/mg tissue), which were significantly lower than those in $CCL_4$ plus silymarin-administrated rats being $8.4{\sim}11.7{\mu}g$/mg ($-30{\sim}-50%$). This collagen reducing effect of liver tissue in $CCL_4$ plus LSR-treated rats was supported by histological observation using microscopy assay. From the results, we conclude that the root of L. salicaria have efficient antioxidant potential and effective antifibrotic activities.

New Liquid Crystal Photoalignment Materials Based on Photosensitive Polyimides Having Long Alkoxy Cinnamate Chains

  • Wu, Jing-Jing;Jeong, Seok-Jin;Lee, Seung-Hee;Lee, Myong-Hoon
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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    • pp.893-896
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    • 2007
  • A series of new photosensitive polyimides having long alkoxy cinnamate chains were synthesized for liquid crystal (LC) photoalignment material. The polymer after irradiating linearly polarized UV light induced homogeneous and stable LC alignment. The chemical structure of the polymeric material was characterized and their photochemical LC alignment behavior was evaluated.

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Global DNA Methylation of Porcine Embryos during Preimplantation Development

  • Yeo, S.E.;Kang, Y.K.;Koo, D.B.;Han, J.S.;Yu, K.;Kim, C.H.;Park, H.;Chang, W.K.;Lee, K.K.;Han, Y.M.
    • 한국가축번식학회지
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    • 제27권4호
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    • pp.309-315
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    • 2003
  • DNA methylation at CpG sites, which is a epigenetic modification, is associated with gene expression without change of DNA sequences. During early mouse embryogenesis, dynamic changes of DNA methylation occur. In this study, DNA methylation patterns of porcine embryos produced in vivo and in vitro were examined at various developmental stages by the immunocytochemical staining method. Interestingly, active demethylation was not observed on the paternal pronucleus of porcine zygotes. However, differences were detected in the passive demethylation process between in vivo and in vitro embryos. There was no change in the DNA methylation state until the blastocyst stage of in vivo embryos, whereas partial demethylation was observed in several blastomeres from a 4 cell stage to a morula stage of in vitro embryos. The whole genome of inner cell mass (ICM) and trophectoderm (TE) cells in porcine blastocysts were evenly methylated without de novo methylation. Our findings demonstrate that genome-wide demethylation does not occur in pig embryos during preimplantation development unlike murine and bovine embryos. It indicates that the machinery regulating epigenetic reprogramming may be different between species.

COMS SYSTEM LEVEL RF COMPATIBILITY TEST SYNTHESIS

  • Lim, Hyun-Su;Park, Durk-Jong;Yang, Hyung-Mo;Ahn, Sang-Il
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2007년도 Proceedings of ISRS 2007
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    • pp.500-503
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    • 2007
  • During the COMS system level test, the RF compatibility will be performed in order to verify that there is no issue in RF interface between satellite and COMS ground station, namely SOC (Satellite Operation Center) before the launch. As used for KOMPSAT1, the RF coaxial cable was chosen to be used to connect satellite and SOC with various advantages as compared with ground antennas. As the preparation step, RF cable and required multiplexer were tested in advance. This paper suggests the way for the RF compatibility tests between the satellite and the SOC over RF cable interface and presents the estimated level diagram as the signal power analysis result.

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