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Thymectomy for the Myasthemia Gravis Patient (중증 근무력증 환자의 흉선 절제술)

  • 정성운;박준호;김종원
    • Journal of Chest Surgery
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    • v.36 no.10
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    • pp.754-758
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    • 2003
  • Backgroun: Thymectomy was known as an effective treatment modality of myasthenia gravis. In this paper, we analyzed the result of thymectomy and the factors affecting the postoperative system improvement. Material and Method: We analyzed the medical records of 50 patients who received the thymectomy for myasthenia gravis from January 1997 to December 2001. Result: 39 patients showed sympton improvement. The effect of thymectomy as a treatment is 78%. There was no statistically significant correlation between postoperative improvement and Sex, Age, the Weight of thymic tissue, preoperative symptom duration, and preoperative mestinon dosage. However, the thymic pathology and low grade preoperative symptoms were affecting the postoperative prognosis. Conclusion: Thymic hyperplasia showed good prognosis compared to thymoma. Low grade preoperative symptoms (Group I or IIA) also showed good prognosis. So, early thymectomy is recommendable for the good treatment results of myasthenia gravis.

Analysis on the Runoff of Urban Watershed using MIKE SWMM Model (MIKE SWMM모형을 이용한 도시유역 유출분석에 관한 연구)

  • Kim Jong Seok;Choe Gyeong Rok;Ahn Jae Hyun;Moon Young Il
    • Proceedings of the Korea Water Resources Association Conference
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    • 2005.05b
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    • pp.862-866
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    • 2005
  • For urban watershed models, the ILLUDAS and SWMM are the popular rainfall-runoff models used in Korea. However, combined sewage systems in urban areas produced problems when a flood occured because of the surcharged precipitation amount which drained to the streams directly. Also, the lack of pipe line data and the difficulties of modeling yield inappropriate modeling results in urban runoff analysis. In addition, rainfall-runoff models in urban areas which use channel routing could have inaccurate and complicated processes. In this paper, the MIKE SWMM model has been applied for the stable runoff analysis of urban areas. Watershed and pipe line data were established by using past inundated records, DEM data, and the numerical pipe line data. For runoff modelings, the runoff block was adapted to a basin and the Extran block using dynamic equations was applied to the sewage system. After comparing to models that exist, it is concluded that the MIKE SWMM model produces reliable and consistence results without distorting the Parameters of the model.

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The Forecasting of Monthly Runoff using Stocastic Simulation Technique (추계학적 모의발생기법을 이용한 월 유출 예측)

  • An, Sang-Jin;Lee, Jae-Gyeong
    • Journal of Korea Water Resources Association
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    • v.33 no.2
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    • pp.159-167
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    • 2000
  • The purpose of this study is to estimate the stochastic monthly runoff model for the Kunwi south station of Wi-stream basin in Nakdong river system. This model was based on the theory of Box-Jenkins multiplicative ARlMA and the state-space model to simulate changes of monthly runoff. The forecasting monthly runoff from the pair of estimated effective rainfall and observed value of runoff in the uniform interval was given less standard error then the analysis only by runoff, so this study was more rational forecasting by the use of effective rainfall and runoff. This paper analyzed the records of monthly runoff and effective rainfall, and applied the multiplicative ARlMA model and state-space model. For the P value of V AR(P) model to establish state-space theory, it used Ale value by lag time and VARMA model were established that it was findings to the constituent unit of state-space model using canonical correction coefficients. Therefore this paper confirms that state space model is very significant related with optimization factors of VARMA model.

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A Case Analysis of Program Outcomes Assessment Systems for Engineering Education Accreditation of South Korea and USA (한국과 미국의 프로그램 학습성과 평가체계 사례분석)

  • Jin, Sung-Hee;Cho, Woo-Sug
    • Journal of Engineering Education Research
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    • v.14 no.2
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    • pp.13-20
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    • 2011
  • This study aimed to seek the ways of improving program outcomes assessment systems for engineering education accreditation of South Korea through performing comparative analysis on those of the United States. Case-study research method was implemented to achieve the research goal. Five university programs, which have been well recognized as good practices in engineering education accreditation in the United States, were selected and analyzed. In addition, those of three universities in South Korea were chosen for comparative analysis, which were reformed by university affiliated Engineering Education Innovative Centers. The analysis results indicated that there were differences in each program's program outcomes, assessment level of program outcomes, evaluation methods on program outcomes achievement, and analysis and improvement records. It was drawn up that the evaluation methods on program outcomes achievement should be paid full attention. For better program outcomes assessment system, however, the followings are in more attention. Firstly, to establish program outcomes reflecting program goal. Secondly, to set up the detailed plans for analysis and quality improvement on program outcomes. Thirdly, to keep continuing efforts on curriculum update.

Response Modification Coefficient Using Natural Period (고유진동주기를 이용한 응답수정계수)

  • 김희중
    • Computational Structural Engineering
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    • v.9 no.4
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    • pp.229-237
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    • 1996
  • In some current procedures, ground motions from different sources have been scaled by their peak ground accelerations and combined to obtain smoothed response spectra for specific regions. As consideration of the inelastic deformation capacity of structure, inelastic deformations are permitted under seismic ground excitation in all codes. In the ATC(Applied Technology Council) and UBC(Uniform Building Code), the inelastic design spectrum is obtained by reducing the elastic design spectrum by a factor that is independent of structural period. In this study, the average of nonlinear response spectra calculated from a sample of 20 records for each event are constructed to obtain the smoothed response spectra. These response spectra are used to examine the effects of structural strength factors such as the yield strength ratio and damping value. Through the regression analysis of nonlinear response of system for a given damping value and yield strength ratio, the required yield strength for seismic design can be estimated for a certain earthquake event. And a response modification coefficient depending on the natural period for current seismic design specifications are proposed.

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Bee-Venom theraphy -Method of Clinical Approach- (봉독요법 -임상활용방법을 중심으로-)

  • 이재동
    • The Journal of Korean Medicine
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    • v.21 no.3
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    • pp.3-8
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    • 2000
  • 1. Definition : Bee-venom therapy does not involve actual bee-stings: it is a treatment method with acquired bee-venom extract through the electric stimulus on the bee, It is injected subcutaneusly on the acupuncture point after refining, according to the diagnosis of constitution and disease. 2. History : Around 2000 B.C., records that Bee-venom was used for therapy were written in the medical book of Babylonia and Papirus of ancient Egypt. Hippocrates, who is called the father of Medicine, said that Bee-venom is Arcanum, which means mysteric medicine. In Oriental medicine, B.C. 200, there was a clinical record that the meat suspended in front of the bee house on the tree in order to get bee-venom, was attached on the lesion. 3. Mechanism of Action : There are two aspects: 1) The effect of stimulating acupunture point It is similar to the chemical moxa. I think that there are several methods of stimulating the acupuncture point: For example, a simple needle is a mechanical stimulus, Moxa is a heating stimulus and electric and Raser acupunture etc. And another stimulus: in the ancient orient, a chemical stimulus called Chungu(Tianjiu), is attached to the lesions by using grinded insects (ex. Mylaris phalerate PALL.) which have toxin. So Bee venom therapy is similar to this. 2) The effect of biochemical ingredients Bee venom consists of 40 kinds of ingredients. For example, me Iii tin, Apamin, Pospholipase A2, MCD peptide, Adolapin and so on. They have effects which have been proven through experimentation l) tonifying mechanism of the body through increasing hormon secretion 2) tonifying immune system through proliferation of WBC, lymphocytes, macrophage 3) anti-inflammatory reaction Therefore Bee venom therapy is the representative 3rd Medicine, which combined East & West medicine. 4. Application of disease : L.B.P and HIVD, O.A, R.A, degenerative arthritis, shoulder pain and other pain diseases. 5. Therapic methods : According to constitution and disease, proper concentration of bee venom is injected on acupunture point, 2 times a week. Generally one term is consisted of 15times. 6. Contraindication : Heart disease, TBc, DM, kidney disease(nephritis), pregnancy, woman in menstruation 3-4 persons per 100,000 persons may have severe allergic reaction.

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Issues of IPR Database Construction through Interdisciplinary Research (학제간 연구를 통한 IPR 데이터베이스 구축의 쟁점)

  • Kim, Dong Yong;Park, Young Chul
    • Journal of the Korea Convergence Society
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    • v.8 no.8
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    • pp.59-69
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    • 2017
  • Humanities and social sciences researchers and database experts have teamed up to build a database of IPR materials prepared by the Institute of Pacific Relations (IPR). This paper presents the issues and solutions inherent in the database construction for ensuring the quality of IPR materials. For the accessibility of the database, we maintain the database on the Web so that researchers can access it via web browsers; for the convenience of the database construction, we provide an integrated interface that allows researchers to perform all tasks in it; for the completeness of IPR materials constructed, we support the responsible input and the responsible approval that identify responsibilities of each IPR material entered; and for the immediacy of the approval, we support an interactive approval process facilitating the input of researchers. We also use database design, query processing, transaction management, and search and sorting techniques to ensure the correctness of IPR materials entered. In particular, through concurrency control using existence dependency relationships between records, we ensure the correctness between the operating system files and their paths. Our future studies include content search, database download and upload, and copyright related work on IPR materials.

Research on Actual Condition of Emergency Patients in Farming and Fishing Villages - In southwest coast district center - (농어촌지역 응급환자 실태조사 - 서남해안 지역을 중심으로 -)

  • Choi, Gil-Soon;Kwon, Hay-Rran
    • The Korean Journal of Emergency Medical Services
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    • v.10 no.1
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    • pp.13-21
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    • 2006
  • Purpose: This study aims to examine characteristics and actual conditions of patients using emergency room at farming and fishing villages, solve overcrowding of emergency room at the tertiary hospital and activate local emergency clinics. Methods: It examines department of diagnosis and treatment, vehicles used, sex, age, residential area, visit hour, length of stay, presence or absence of trauma, measures after first aid and degree of severity based on medical records of 6,740 patients using emergency room at farming and fishing villages from Jan. 1 to Dec. 31, 2005. Conclusion : 1. Sex distribution of patients of emergency room was male 54.9% and female 45.1% and age distribution between over 40 and below 50 was most as 15.9%. 2. Transport means to emergency room were 91.4 of private car and others (public transport and going on foot), 7.5 of 119, 129 and police car and 1.0% of ambulance. 3. According to distribution of residential areas of emergency patients, 38.9% were Eup area, 42.1% Myeon area, 11.4% distant area and 7.5% adjacent area. 4. According to distribution of emergency patients by department of diagnosis and treatment, internal medicine was most as 35.8% and 55% of patients visited emergency room from 3:31 p.m. to 11:30 p.m.. 5. According to total hours of diagnosis and treatment of subjects, 51.2% were within 30min. and cases of non-trauma disease were 68.2%. 6. According to degree of emergency of emergency patients, non-emergency cases were 65.3%, urgent cases 27.7% and emergency cases 7.0% and 74.2% of patients returned home after first aid and 20.6% of them hospitalized. In conclusion, characteristics and diversification of patients should be examined and efforts by government and local medical institutions which must organize emergency system and facility and personnel levels suitable to regional conditions are needed in order to prevent overcrowding of emergency center of the tertiary hospital and activate local emergency center.

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Clinical and Neuroimaging Outcomes of Surgically Treated Intracranial Cysts in 110 Children

  • Lee, Eun-Jung;Ra, Young-Shin
    • Journal of Korean Neurosurgical Society
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    • v.52 no.4
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    • pp.325-333
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    • 2012
  • Objective : The indications and optimal surgical treatments for intracranial cysts are controversial. In the present study, we describe long-term clinical and neuroimaging results of surgically treated intracranial cysts in children. The goal of this study is to contribute to the discussion of the debate. Methods : This study included 110 pediatric patients that underwent surgeries to treat intracranial cysts. Endoscopic cyst fenestrations were performed in 71 cases, while craniotomies and cyst excisions (with or without fenestrations) were performed in 30 patients. Cystoperitoneal shunts were necessary for nine patients. Long-term results were retrospectively assessed with medical and neuroimaging records. Results : Clinical and radiological improvement was reported in 87.3% and 92.8% of cases, respectively, after endoscopic neurosurgery, and in 93.3% and 100% using open microsurgery whereas 88.9% and 85.7% after shunt operation. There were no statistical differences in clinical outcomes (p=0.710) or volume reductions (p=0.177) among the different surgeries. There were no mortalities or permanent morbidities, but complications such as shunt malfunctions, infections, and subdural hematomas were observed in 56% of the patients that had shunt operations. A total of 13 patients (11.8%) underwent additional surgeries due to recurrences or treatment failures. The type of surgery performed did not influence the recurrence rate (p=0.662) or the failure rate (p=0.247). Conclusion : Endoscopic neurosurgeries are less invasive than microsurgeries and are at least as effective as open surgeries. Thus, given the advantages and complications of these surgical techniques, we suggest that endoscopic fenestration should be the first treatment attempted in children with intracranial cysts.

Factors Associated with the Prehospital Delay in Acute Myocardial Infarction (급성 심근경색증 환자의 병원내원시간 지연에 관련된 요인)

  • Choi, Kyu-Chul;Choi, Sung-Soo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.2
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    • pp.707-712
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    • 2013
  • In patients with acute myocardial infarction (AMI), the delay from symptom onset to hospital arrival has a critical effect on morbidity and mortality. This study examined to find out the determinants of the prehospital delay in patients with AMI. The study sample consisted of 597 patients hospitalized with AMI between Jan and Dec 2009. Demographic, medical history, and clinical data were abstracted from the hospital medical records of patients with confirmed AMI, the prehospital delay was categorized as less than or greater than 6 hours. Older age, low socioeconomic status(medical aid), and low use of Emergency medical system were associated with delays in seeking emergency care for Acute myocardial infarction. Education programs to improve patient knowledge of acute coronary syndrome symptoms and promote patient responsiveness with regard to seeking medical care should be used to reduce the prehospital delay time, especially in the low socioeconomic group.