• Journal of Korean Society of Transportation
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• v.24 no.3 s.89
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• pp.103-112
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• 2006

For recent innovation of If technology and the beginning of Digital Multimedia Broadcasting (DMB) service, it has been dramatically increased to setup TV system in a car for watching TV and receiving traffic Information. Watching TV while driving would distract a driver s cognitive and visual attention as eating food, operating the radio, using a cell phone. However, there is paucity of empirical researches and it is uncertain how watching TV in driving impacts on the driver's cognition in the concrete. Therefore, we surveyed domestic drivers on the attitude watching TV while driving as well as conducted experiments through a driving simulator. Especially, we recruited two groups of participants to explore the effects of watching TV on driving behavior. The result proved that the participants who watched TV while their driving had relatively narrower the attention span than the Participants who did not watch TV. Also, those who watched TV drove with less stability and more urgent operations of the brake and accelerator than those who did not watched TV Finally, we discussed limitations and implications of the study.

• Korean Journal of Health Education and Promotion
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• v.25 no.3
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• pp.167-181
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• 2008

The prevention of life-style related diseases is an increasingly important issue in Japan, because not only have the number of patients with life-style related diseases increased but also medical care costs. This paper gives recent strategies for the prevention of cardiovascular diseases through life-style modification. Health objectives for the year 2010, called "Healthy Japan 21", were established in 2000 by the Ministry of Health, Labour and Welfare and the Health Promotion Act was enacted in 2002 to promote this health policy. However, the prevention efforts for life-style related diseases have not been effective in regard to the evaluation of the strategy objectives. The reform of the medical care system which included a new nationwide prevention strategy for life-style related diseases was presented in 2006. The new strategy starting from April 2008 included a "specific health checkup" and "specific health education" for those with metabolic syndrome. The specific health checkup is used to screen people according to criteria of the metabolic syndrome and divide them into 3 groups. These groups will receive specific health education. The purpose of this strategy is the early detection of those who have cardiovascular risk factors, and the early management of the clustering of cardiovascular risk factors of obese people aged 40-74 years old. It is mandatory for every insurer to conduct a specific health checkup and specific health education under the new Act. The implementation rate of the specific health checkup and the specific health education, and a reduction rate of individuals with metabolic syndrome among insured people will be evaluated every year. The national objective is to increase the rate of those undergoing the specific health checkup to 80% and the rate of those receiving the specific health education to 60% by the year 2015. The national objective also targeted a reduction rate of 25% for those with metabolic syndrome. This new strategy will be the biggest intervention trial in the world, and it will produce a big health care market in Japan. Not only public administrative institutions but also private institutions are now preparing to take part in this new strategy. However, various tasks remain, such as training more professionals in health education, developing more evidence based practices, and encouraging cooperation with various sectors, to enforce this new strategy.

• Tuberculosis and Respiratory Diseases
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• v.45 no.3
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• pp.546-552
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• 1998

Background: Up to 90% of a theophylline dose is biotransformed, by interaction with one or more the variants of the cytochrome P-450 drug metabolism system. Macrolides affect the elimination of theophylline by influencing on the microsomal enzyme systems. We evaluate the effect of erythromycin and new macrolides on the serum theophylline level and clearance. Method : Subjects consisted of moderate asthmatic patients with normal renal and hepatic functions. All subjects were non-smokers and treated with oral theophylline 400 mg per day. We randomly assigned 53 patients into four groups. Each group was treated with one macrolides, the first group erythromycin(n:19, 500 mg bid), second roxithromycin (n:14. 150 mg bid), third clarithromycin (n:10, 250 mg bid) and fourth azithromycin(n:10, 250 mg bid). We measured the serum theophylline level and clearance at three intervals, at pretreatment, after the first and fourth week after receiving the following macrolides, erythromycin, roxithromycin and clarithromycin. When azithromycin was administered, the serum theophylline level was measured at pretreatment and after one week of treatment They were measured by a computerized program of Bayesian method. Results : When compared with control, erythromycin and roxithromycin-treated groups had a significantly elevated serum theophylline level and decreased clearance. However, there were no significant changes of the serum theophylline level and clearance in clarithromycin and azithromycin-treated groups. Conclusion : These results suggest that theophylline dose may need to be readjusted and have periodic drug monitoring when erythromycin or roxithromycin is administered concurrently.

• 대한공업교육학회지
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• v.34 no.2
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• pp.346-362
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• 2009

The purpose of this study was to develop the handy non-contact measurement device of the surface roughness by using the optical fiber sensor. The advantages of fiber optic sensors are high-speed responsibility, non-effect of the magnetic, convenience of the product and high precision. The measurement theory for surface roughness of optical fiber sensor is one to one correspondence between the reflected light intensity based on the surface roughness of the object and the measurement value of previously known for surface roughness. The reflected light intensity was determined using the distance to the surface from the sensor probe and the limit reflection angle based on the surface roughness. Therefore, in this study, the sensor probe was produced for determining the value of surface roughness only using the limit reflection angle based on the surface roughness with the fixed distance from the surface. A prototype measurement system was composed of a transmitting part, a receiving part and a signal processing circuit. The materials of standard measurement which was used in this experiment were SM45C, STS303 and Al60. According to the results of this study, approximation surface roughness formulas which was deduced from the correlation of between the standard surface roughness and the sensing output were verified that they were effect against the surface roughness measurement value of the option sample. And handy optical fiber surface roughness measurement device which was produced by an order was verified that it was effect for measuring of the precision surface roughness.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.57
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• pp.283-303
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• 2013

When a trade conflict arises related to an officially supported export credit programme, The World Trade Organization(WTO), decides on whether the programme is a forbidden subsidy stipulated in the Agreement on Subsidies and Countervailing Measures(the ASCM Agreement). Korea was taken to the WTO panel two times for the export credit programme. One is the semiconductor case in 2002 and the other was the shipbuilding disputes in 2004. And, In 2012, the U.S. Commerce Department ruled K-SURE's export insurance for Korean refrigerator manufacturers as a forbidden subsidy even if the case was not taken to the WTO. This paper examines the significance of export credit programmes on the WTO ASCM Agreement and discusses how to operate these programmes so they would not infringe upon the Agreement by analyzing the actual cases of WTO subsidy conflicts that involved Korean enterprises in relation to export credit programmes for the purpose of determining the related issues and impacts. From this research the results were as follows: First, on whether export credit is a prohibited subsidy, the deciding factor was whether a benefit has been conferred to the beneficiary. On the presence of a benefit, the WTO panel used market benchmarks as the main criteria. Thus, official export credit agencies(ECAs) should be careful not to provide export credit support which had been granted to the beneficiary at better than market terms. Second, in the case of export credit, the special status of ECA as a public body receiving government support itself does not constitute a subsidy. However, caution must be taken not to provide export credit that may lead to WTO ASCM subsidy conflicts involving a certain exporter or industry by setting up clear and valid regulations and fair work processes in the operation of export credit programmes. Third, item (j) of Annex I cannot be interpreted reversely as this item is for interpreting the presence of a prohibited subsidy, not the presence of a benefit. Thus, an export credit program that confers a financial contribution, a benefit and specificity, could qualify as a prohibited subsidy. Fourth, ECAs not only have to maintain long-term account balance but also introduce additional measures to meet this long-term balance such as a clear and systematic premium system. Finally, export credit programmes that are not defined in item (j) of Annex I of the ASCM Agreement would not deemed as an prohibited export subsidy as long as the continued support of the programmes are not being forced.

• Journal of Korean Ophthalmic Optics Society
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• v.16 no.2
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• pp.107-115
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• 2011

Purpose: To design and fabricate the distributed auto edging machine for the development. Methods: We got the necessary data needed in design by using CAD. Based on the these data, we fabricated the trial product for the development of the distributed auto edging machine. Results: The patternless mode could be operated by receiving the eyesize data from the auto lay-outer with the RS232C transmission system and the pattern mode could be operated by setting the pattern on the left side of the machine. The distributed auto edging machine were composed with combinations of many elements; head, auto arm, pattern clamp and grinding wheels. The head part controlled the grinding of ophthalmic lens by operating the vertical and horizontal motors. The wheels part was comprised of glass mode, plastic mode, V-bevel mode and polish mode. The slide in the auto arm was equipped on the below of the patten and the slide could hold up the pattern which was rotated by fixed shaft. The pattern clamp could move the head part to the up and down or right or left way by the manual operation of optometrists. Conclusions: We could succeed in making the trial product by applying it to the development of the distributed auto edging machine which could be used as the patternless mode and pattern mode, selectively. Therefore, it was confidently expected that this product was very helpful for the optometrists to dispense the ophthalmic lens because of its cost-efficiency and convenience.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.47 no.4
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• pp.399-405
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• 2014

We investigated the effects of feeding rate on the growth performance, blood components, and histology of growing olive flounder Paralichthys olivaceus. Optimum feeding rate (initial fish mean weight : $316.7{\pm}6.18g$) was determined under the optimum water temperature. Two replicated groups of fish were fed a commercial diet at rates of 0%, 0.4%, 0.6%, and 0.8% of body weight (BW) per day, and to satiation. Feeding trial was conducted using a flow-through system with 10 1.2-metric ton aquaria receiving filtered seawater at $21-24^{\circ}C$ for 3 weeks. Weight gain (WG) and specific growth rate (SGR) were significantly higher in fish fed to satiation (1.0% BW/day) than in those in other treatments. These parameters were negative and significantly lower in the starved fish than in fish fed the experimental diet at all feeding rates. There were no significant differences in WG and SGR among fish fed at 0.4%, 0.6%, and 0.8% BW/day. Hematocrit and hemoglobin in fish fed to satiation were significantly lower than those in other treatments. Histological changes of fish fed at 0.6% BW/day indicated that this group was in the best condition; differences were not found in tissues of fish fed at 0%, 0.6% and 1.0% BW/day. Broken-line regression analysis of weight gain showed that the optimum feeding rate of olive flounder weighing 317 g was 0.99% BW per day at the optimum water temperature.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.11
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• pp.770-777
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• 2017

Building information modeling (BIM) has been receiving attention as an integrated information model instead of CAD since the 2000s. BIM technology was first used in the architectural field and was later introduced to the civil engineering field. However, the government announced a plan for the application of BIM to 20% of all SOC projects from 2020, so the adoption of BIM technology is expected to accelerate. In order to successfully adopt BIM, a systematic structure should be supported for integrated design information and implementation technology. Also, it is important to establish the relationship between information systems because many complicated factors are intertwined in the construction industry. In this study, we propose a framework for constructing integrated information through identifying the information relations for introducing BIM in the civil engineering industry. We applied this framework to a bridge project to confirm its effectiveness. This study can be applied to the integrated management of the construction process and costs by introduction of a work breakdown structure (WBS) to BIM. In addition, this study is expected to contribute to the adoption of BIM in the civil engineering field through the proposal of information system standardization in this field.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2669-2673
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• 2012

Purpose: Pancreatic carcinoma is one of the most malignant tumors of the alimentary system, with relatively high incidence rates. The purpose of this study was to assess the efficacy and safety of two regimens for advanced pancreatic carcinoma: continuous transarterial infusion versus systemic venous chemotherapy with gemcitabine and 5-fluorouracil. Methods: Of the 48 patients with advanced pancreatic carcinoma receiving chemotherapy with gemcitabine and 5-fluorouracil, 24 received the selective transarterial infusion, and 24 the systemic chemotherapy. For the continuous transarterial infusion group (experimental group), all patients received gemcitabine 1000 mg/$m^2$, given by 30-minute transarterial infusion, on day 1 of a 4-week cycle for 2 cycles, and a dose of 600 mg/$m^2$ 5-fluorouracil was infused on days 1~5 of a 4-week cycle for 2 cycles. For the systemic venous group (control group), gemcitabine and 5-fluorouracil were infused through a peripheral vein, a dose of 1000 mg/$m^2$ gemcitabine being administrated over 30 min on days 1 and 8 of a 4-week cycle for 2 cycles, and a dose of 600 mg/$m^2$ 5-fluorouracil was infused on days 1~5 of a 4-week cycle for 2 cycles. The effectiveness and safety were evaluated after 2 cyclesaccording to WHO criteria. Results:The objective effective rate in transarterial group was 33.3% versus 25% in the systemic group, the difference not being significant (P=0.626). Clinical benefit rates(CBR) in the transarterial and systemic groups were 83.3% and 58.3%, respectively (P=0.014). The means and medians for survival time in transarterial group were higher than those of the systemic group (P < 0.005). at the same time, the adverse effects did not significantly differ between the two groups (P > 0.05). Conclusion: Continuous transarterial infusion chemotherapy with gemcitabine and 5-fluorouracil could improve clinical benefit rate and survival time of patients with advanced pancreatic carcinoma, compared with systemic venous chemotherapy. Since adverse effects were limited in the transarterial group, the regimen of continuous transarterial infusion chemotherapy can be used more extensively in clinical practice. A CT and MRI conventional sequence can be used for efficacy evaluation after chemotherapy in pancreatic carcinoma.

• Journal of Nutrition and Health
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• v.14 no.2
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• pp.59-70
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• 1981

The objective of this study is to induce the primary characteristics of phenylketonuria in infant rats during the first 2 weeks after birth. The critical biochemical parameter in the development of phenylketonuria is the elevation of plasma phenylalanine while tyrosine is maintained at a relatively low level. A PKU-like condition was induced in infant rats during the first 2 weeks after birth using a modification of our previously published procedure for the development of a temporary (1 to 3 days) PKU-like condition. Phenylalanine was administered by stomach intubation every 6 hours (starting at 6:00 a.m.) at a dose level of 400mg per kg body weight (after birth-day 2 thru 5) and 500mg per kg body weight (day 6 thru 14). Amethopterin was given at 0.00625 or 0.0125mg per kg body weight (day 3 thru 14) and p-chlorophenylalanine at 50 mg per kg body weight (day 5 thru 14) at 9:00 a.m. and 9:00 p.m. At the times measured (6,10 and 14 days) plasma phenylalanine/tyrosine (P/T) ratios were elevated from a normal value of the or less to values ranging from 6 to 15. During the second week after birth a staggering gait, abnormal stance and decreased social behavior were also observed. None of these PKU-like characteristics were apparent in the three control groups receiving (a) no phenylalanine or inhibitors, (b) phenylalanine alone, or (c) inhibitors alone. The establishment of these primary biochemical characteristics of phenylketonuria by stomach intubation of phenylalanine and a combination of low dose levels of enzyme inhibitors to infant rats provides an experimental system which should he valuable for extensive biochemical, histological and behavioral studies in phenylketonuria.