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Antimicrobial Activity of Some Schiff Bases Derived from Benzoin, Salicylaldehyde, Aminophenol and 2,4 Dinitrophenyl Hydrazine

  • Jesmin, Mele;Ali, M. Mohsin;Salahuddin, M.S.;Habib, M. Rowshanul;Khanam, Jahan Ara
    • Mycobiology
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    • v.36 no.1
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    • pp.70-73
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    • 2008
  • The antibacterial and antifungal activities of three schiff bases were evaluated against some pathogenic bacteria and fungi. Parallel experiments were also carried out with standard drugs (Kanamycin for bacteria and Nystatin for fungi). Two compounds [N-(1-phenyl-2-hydroxy-2phenylethylidine)-2',4' dinitrophenyl hydrazine, abbreviated as PDH and N-(2-hydroxy benzylidine)-2'-hydroxy imine, abbreviated as HHP] showed significant antimicrobial activities. The rest one [N-(l-phenyl 2-hydroxy-2 phenyl ethylidine) 2'-hydroxy phenyl imine, abbreviated as PHP] showed moderate activity. All these three compounds were found to possess pronounced cytotoxic effect. These compounds can be considered as potent antimicrobial agents.

Effects of Plant Extracts on Conidial Germination, Mycelial Growth and Sporulation of Fungi Isolated From Poultry Feed

  • Islam, M. Rafiqul;Alam, Shahidul;Rahman, M. Ziaur;Chowdhury, S.P.;Begum, M.F.;Akhter, Nargis;Alam, M.S.;Han, Kee-Don;Lee, Min-Woong
    • Mycobiology
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    • v.31 no.4
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    • pp.221-225
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    • 2003
  • Effect of ethanolic extracts of Lawsonia inermis, Azadirachta indica, Vinca rosea, Tagetes patula, Ocimum sanctum, Colocasia antiquorum, Adhatoda vasica, Moringa oleifera, Datura metel and Curcuma longa leaf on conidial germination, mycelial growth and sporulation of Aspergillus flavus, A. niger and A. fumigatus were examined. The conidial germination of A. flavus and A. fumigatus were most inhibited by the extract of L. inermis, while that of A. niger was inhibited by A. indica. Other tested plant extracts have a good effect on conidial germination on the selected fungi. The highest mycelial growth of A. flavus(37 mm) was found in V. rosea, but in case of A. niger and A. fumigatus it(38 and 39 mm) was found in D. metel. The lowest(4, 9 and 6 mm) respectively mycelial growth of these fungi found in L. inermis. The highest sporulation($75{\times}10^4/ml$) of A. flavus was counted in V. rosea, but in case of A. niger and A. fumigatus those($45{\times}10^4$ and $55{\times}10^4/ml$) were in D. metel and the lowest($5{\times}10^4,\;12{\times}10^4\;and\;9{\times}10^4/ml$) respectively sporulation of these fungi counted in L. inermis plant extract medium.

Effect of Fungicides and Plant Extracts on the Conidial Germination of Colletotrichum gloeosporioides Causing Mango Anthracnose

  • Imtiaj, Ahmed;Rahman, Syed Ajijur;Alam, Shahidul;Parvin, Rehana;Farhana, Khandaker Mursheda;Kim, Sang-Beom;Lee, Tae-Soo
    • Mycobiology
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    • v.33 no.4
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    • pp.200-205
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    • 2005
  • In Northern Bangladesh, generally mango trees are planted as agroforest that gives higher Net Present Value (NPV) than traditional agriculture. Mango anthracnose caused by Colletotrichum gloeosporioides Penz. is seen as a very destructive and widely distributed disease, which results in poor market value. Five fungicides such as Cupravit, Bavistin, Dithane M-45, Thiovit and Redomil were tested against conidial germination of C. gloeosporioides. Dithane M-45 and Redomil were the most effective when the conidia were immersed for $10{\sim}20$ minutes at $500{\sim}1000\;ppm$ concentrations. Antifungal activities of 13 plant extracts were tested against conidial germination of C. gloeosporioides. Conidial germination of C. gloeosporioides was completely inhibited in Curcuma longa (leaf and rhizome), Tagetes erecta (leat) and Zingiber officinales (rhizome) after 15 minutes of incubation respectively.

Effect of Citrus macroptera Fruit Pulp Juice on Alteration of Caspase Pathway Rendering Anti-Proliferative Activity against Ehrlich's Ascites Carcinoma in Mice

  • Hasan, Md. Mahmudul;Islam, Md. Shihabul;Hoque, Kazi Md. Faisal;Haque, Ariful;Reza, Md Abu
    • Toxicological Research
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    • v.35 no.3
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    • pp.271-277
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    • 2019
  • Citrus macroptera (Rutaceae) has long been used in folk medicine in Bangladesh. Considering the folkloric context, this study was aimed to scrutinize anti-proliferative activity of C. macroptera fruit pulp juice (CMFPJ) against Ehrlich's ascites carcinoma (EAC). The anti-proliferative capacity of CMFPJ was investigated and confirmed primarily using MTT assay. In vivo anti-proliferative aptitude of CMFPJ was investigated with 25, 50, and 100 mg/kg/day intraperitoneal (i.p.) treatment. Anti-proliferative efficacy of CMFPJ was assessed based on EAC growth inhibition. CMFPJ inhibited EAC growth in vitro in a dose-dependent manner. And the percentages of in vivo EAC growth inhibition were 19.53, 49.2, and 68.9% at 25, 50, and 100 mg/kg CMFPJ respectively. CMFPJ significantly induced expression of apoptosis regulatory genes caspase-8, caspase-9, cytochrome-c, and caspase-3. This considerable anti-cancer activity was perhaps due to combinatorial effect of lectin, polyphenols, and flavonoids present in CMFPJ.

A GENERAL MULTIPLE-TIME-SCALE METHOD FOR SOLVING AN n-TH ORDER WEAKLY NONLINEAR DIFFERENTIAL EQUATION WITH DAMPING

  • Azad, M. Abul Kalam;Alam, M. Shamsul;Rahman, M. Saifur;Sarker, Bimolendu Shekhar
    • Communications of the Korean Mathematical Society
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    • v.26 no.4
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    • pp.695-708
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    • 2011
  • Based on the multiple-time-scale (MTS) method, a general formula has been presented for solving an n-th, n = 2, 3, ${\ldots}$, order ordinary differential equation with strong linear damping forces. Like the solution of the unified Krylov-Bogoliubov-Mitropolskii (KBM) method or the general Struble's method, the new solution covers the un-damped, under-damped and over-damped cases. The solutions are identical to those obtained by the unified KBM method and the general Struble's method. The technique is a new form of the classical MTS method. The formulation as well as the determination of the solution from the derived formula is very simple. The method is illustrated by several examples. The general MTS solution reduces to its classical form when the real parts of eigen-values of the unperturbed equation vanish.

In Vitro Effect of Fungicides, Plant Extracts and Smoke on Conidial Germination of Fusarium oxysporum Root Rot Pathogen of Piper betle

  • Alam, Shahidul;Islam, M. Rafiqul;Sarkar, Montaz Ali;Chowdhury, Arfatun Nahar;Alam, M.S.;Lee, Min-Woong
    • Mycobiology
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    • v.32 no.1
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    • pp.42-46
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    • 2004
  • Five fungicides such as rovral, bavistin, cupravit, dithane M-45 and thiovit were tested against conidial germination of Fusarium oxysporum. Dithane M-45 was the most effective against the fungus. Rests of the fungicides were more or less effective in the inhibition of conidial germination after $5{\sim}30$ minutes immersion in $500{\sim}2500$ ppm concentration. Five plant extracts(leaf extracts of Ocimum sanctum, Lantana camera, Calotropis procera, Azadirachta indica and Vinca rosea) found to be more or less effective against the fungus. 'Dhup' somke have good inhibitory effect on conidial germination of F. oxysporum.

Production of Virus Free Seeds using Meristem Culture in Tomato Plant under Tropical Conditions

  • Alam M.F.;Banu M.L.A.;Swaraz A.M.;Parvez S.;Hossain M.;Khalekuzzaman M.;Ahsan N.
    • Journal of Plant Biotechnology
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    • v.6 no.4
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    • pp.221-227
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    • 2004
  • Protocol was established for production of virus free healthy seeds using meristem ($0.3-0.5\;\cal{mm}$ in size) culture and field management under net house condition in tomato. The isolated meristem was found well established in MS liquid medium containing $0.1\;\cal{mg}\;1^{-1}\;of\;GA_3$. For shoot and root development either from primary meristem or from nodal segment of meristem derived plants, semisolid MS medium having $0.5\;\cal{mg}\;1^{-1}$ of IBA was found most effective. The elimination of the studied viruses (ToMV, CMV, ToLCV) in meristem-derived plants was confirmed by DAS-ELISA test. For field management of the virus eradicated meristem-derived plants, use of net house was found very effective measures to check viral vector visit and eventually infection. The meristem-derived plants were vigor and high yielder than the native seed derived plants and produced healthy seeds. Due to stop vector visit, no viral symptoms were observed in both $R_1\;and\;R_2$ plants cultivated in net house condition. Starting of viral infestation was observed in $R_2$ generation when they were planted in open house condition without control of vector visit. Therefore, for management of viral diseases, use of virus free meristem derived plantlets and their subsequent cultivation in soil under net house condition without using any vector killing insecticide can be recommended for producing healthy seeds in tomato. The developed protocol for environmentally healthy tomato seed production in Bangladesh may be used in the countries having similar tropical like environment conducive for viral vector visit.

Antishigellosis and Cytotoxic Potency of Crude Extracts and Isolated Constituents from Duranta repens

  • Nikkon, Farjana;Habib, M. Rowshanul;Karim, M. Rezaul;Hossain, M. Shamim;Mosaddik, M. Ashik;Haque, M. Ekramul
    • Mycobiology
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    • v.36 no.3
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    • pp.173-177
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    • 2008
  • The crude ethanol extracts (stem and fruits), their fractions and two triterpenes, $\beta$-Amyrin and 12-Oleanene 3$\beta$, 21$\beta$-diol, isolated as a mixture from the chloroform soluble fraction of an ethanolic extract of Duranta repens stem, were evaluated for antibacterial, antifungal activities by the disc diffusion method and cytotoxicity by brine shrimp lethality bioassay. The structures of the two compounds were confirmed by IR, $^1H$-NMR, $^{13}C$-NMR and LC-MS spectral data. The chloroform soluble fraction of stem and ethanol extract of fruits possess potent antishigellosis activity and also exhibited moderate activity against some pathogenic bacteria and fungi but the isolated compound 1 (mixture of $\beta$-Amyrin and 12-Oleanene 3$\beta$, 21$\beta$-diol) showed mild to moderate inhibitory activity to microbial growth. The minimum inhibitory concentrations (MICs) of the extracts (stem and fruits), their fractions and compound 1 were found to be in the range of 32$\sim$128 ${\mu}g/ml$. The chloroform soluble fractions of stem and ethanol extract of fruit showed significant cytotoxicity with $LC_{50}$ value of 0.94 ${\mu}g/ml$ and 0.49 ${\mu}g/ml$, respectively against brine shrimp larvae.

Research Trends in Library and Information Science in Bangladesh: An Analytical Study

  • Islam, Md. Shariful;Islam, Md. Nazmul;Mondal, Madhob
    • Journal of Information Science Theory and Practice
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    • v.6 no.2
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    • pp.36-45
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    • 2018
  • The utmost intention of this work is to identify various field areas which are most prevalent in library and information science education. The study also denotes the rate of tendency on the rapid growth and development of research production among information specialists in Bangladesh. In order to carry out the study, an extensive literature review was carefully done to collect the basic elements of research patterns. It is noted that in the period of 1980-2016, 200 articles were published in library and information science by Bangladeshi researchers in 62 journals. In this article a total of 200 articles were reviewed. The result of the present study shows that the ratio of female authors had fewer contributions than male authors did. The majority of articles were published from the United Kingdom. The study also shows that the largest numbers of articles (19 papers, 9.50%) were published in the Social Science Journal of the University of Rajshahi from Bangladesh. The paper also shows that about 71.50% of papers have been cited while 28.50% of papers did not receive any citation. The present research might be helpful for revealing the country's research trends in library and information science. However, this study may also inspire development of a subject-based indigenous database and can act as an important device for research scholars.

Optimal Conditions for Antimicrobial Metabolites Production from a New Streptomyces sp. RUPA-08PR Isolated from Bangladeshi Soil

  • Ripa, F.A.;Nikkon, F.;Zaman, S.;Khondkar, P.
    • Mycobiology
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    • v.37 no.3
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    • pp.211-214
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    • 2009
  • An actinomycete strain was isolated from northern part of Bangladesh and identified as a new Streptomyces species on the basis of its morphological, biochemical, cultural characteristics and 16S rRNA data. Attempts were made to optimize the culture conditions for the production of antimicrobial metabolites by this strain. Antimicrobial metabolites production was started after 7 days of incubation of culture broth and reached its maximum levels after 10 days and thereafter gradually decreased. The maximum production of antimicrobial metabolites was obtained when the culture medium pH was adjusted to 8. The optimum temperature for antimicrobial metabolites production was $39^{\circ}C$, indicated the new strain as mesophilic organism. Basel medium supplemented with glucose and yeast extract as carbon and nitrogen sources, respectively, was proved to be the best for the production of bioactive metabolites. Maximum production of bioactive metabolites was when NaCl concentration was 1% and among different minerals tested, $K_2HPO_4$ and NaCl showed positive influence on antibiotic production by the strain.