• Broadcasting and Media Magazine
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• v.7 no.3
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• pp.94-103
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• 2002

본 논문은 전송 오류가 존재하는 환경에서 사용될 수 있는 오류 내성을 갖는 비트스트림을 생성하기 위한 H.26L부호화 알고리즘을 소개한다. 소개되는 새로운 부호화 알고리즘은 기존의 GOB 단위 forced intra-refreshment 기법이나 multiple decoder simulation 기반 RD 최적화 기법에 비해서 RD 특성 등에서 대단히 우수한 성능을 보인다.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.10B
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• pp.1470-1474
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• 2001

8B/10B 선로부호를 채택한 기가비트 이더넷 PCS 수신측에서는 동기부의 바이트 동기획득과 수신부의 디코딩을 위해 Running Disparity(RD) 에러인 데이터열을 검출해야 한다. 기존의 RD 에러 검출 방법은 직렬 입력 비트에서 RD 에러를 검출하였으나 제안하는 RD 에러 검출 방법은 125MHz 속도의 10비트 데이터열을 받아 4비트열과 6비트열로 나누어 바이트 클럭에 따라 RD를 계산하고 계산된 이전의 RD값과 현재의 RD값을 비교하며 RD 위반 에러 데이터를 검출한다. 이는 기존의 RD 에러 검출 방법이 비트 클럭과 니블 클럭에 따라 RD 에러를 검출하기 때문에 야기되는 초고속 처리에 대한 한계를 해결한 것이며 기가비트 이더넷에 적합한 새로운 RD 에러 검출 방법이다.

• Molecules and Cells
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• v.37 no.11
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• pp.795-803
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• 2014

To withstand ever-changing environmental stresses, plants are equipped with phytohormone-mediated stress resistance mechanisms. Salt stress triggers abscisic acid (ABA) signaling, which enhances stress tolerance at the expense of growth. ABA is thought to inhibit the action of growth-promoting hormones, including brassinosteroids (BRs). However, the regulatory mechanisms that coordinate ABA and BR activity remain to be discovered. We noticed that ABA-treated seedlings exhibited small, round leaves and short roots, a phenotype that is characteristic of the BR signaling mutant, brassinosteroid insensitive1-9 (bri1-9). To identify genes that are antagonistically regulated by ABA and BRs, we examined published Arabidopsis microarray data sets. Of the list of genes identified, those upregulated by ABA but downregulated by BRs were enriched with a BRRE motif in their promoter sequences. After validating the microarray data using quantitative RT-PCR, we focused on RD26, which is induced by salt stress. Histochemical analysis of transgenic Arabidopsis plants expressing RD26pro:GUS revealed that the induction of GUS expression after NaCl treatment was suppressed by co-treatment with BRs, but enhanced by co-treatment with propiconazole, a BR biosynthetic inhibitor. Similarly, treatment with bikinin, an inhibitor of BIN2 kinase, not only inhibited RD26 expression, but also reduced the survival rate of the plant following exposure to salt stress. Our results suggest that ABA and BRs act antagonistically on their target genes at or after the BIN2 step in BR signaling pathways, and suggest a mechanism by which plants fine-tune their growth, particularly when stress responses and growth compete for resources.

• The Journal of Internal Korean Medicine
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• v.26 no.2
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• pp.482-488
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• 2005

This study was designed to evaluate the effects of the oriental medicine(Sojeockjeongwonsan) on a Jeock-Jeung patient. The clinical data was analyzed on a patient with Jeock-Jeung, deemed due to Gangiulgyul(肝氣鬱結) and Junggiheoyak(正氣虛弱). The patient’s main symptoms were abdominal pain and abdominal mass. The patient was admitted to Dae-Gu Hanny University Dae-Gu Oriental Medicine Hospital. Clinical symptoms, including abdominal pain, abdominal mass and general condition, improved after treatment. This study suggests that Sojeockjeongwonsan is significantly effective in treatment of a Jeock-Jeung.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.3
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• pp.229-235
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• 2013

Among several animal models of retinitis pigmentosa (RP), the more recently developed rd10 mouse with later onset and slower rate of retinal degeneration than rd1 mouse is a more suitable model for testing therapeutic modalities. We therefore investigated the time course of retinal degeneration in rd10 mice before adopting this model in our interventional studies. Electroretinogram (ERG) recordings were carried out in postnatal weeks (PW) 3~5 rd10 (n=23) and wild-type (wt) mice (n=26). We compared the amplitude and implicit time of the b-wave of ERG records from wt and rd10 mice. Our results showed that b-wave amplitudes in rd10 mice were significantly lower and the implicit time of b-waves in rd10 mice were also significantly slower than that in wt mice ($20{\sim}160{\mu}V$ vs. $350{\sim}480{\mu}V$; 55~75 ms vs. 100~150 ms: p<0.001) through PW3 to PW5. The most drastic changes in ERG amplitudes and latencies were observed during PW3 to PW4. In multichannel recording of rd10 retina in PW2 to PW4.5, we found no significant difference in mean spike frequency, but the frequency of power spectral peak of local field potential at PW3 and PW3.5 is significantly different among other age groups (p<0.05). Histologic examination of rd10 retinae showed significant decrease in thickness of the outer nuclear layer at PW3. TUNEL positive cells were most frequently observed at PW3. From these data, we confirm that in the rd10 mouse, the most precipitous retinal degeneration occurs between PW3~PW4 and that photoreceptor degeneration is complete by PW5.

• Archives of Pharmacal Research
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• v.26 no.5
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• pp.375-382
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• 2003

Effects of ginsenosides on nitric oxide (NO) production induced by lipopolysaccharide plus TNF-$\alpha$ (LNT) were examined in C6 rat glioma cells. Among several ginsenosides, ginsenoside Rd showed a complete inhibition against LNT-induced NO production. Ginsenoside Rd attenuated LNT-induced increased phosphorylation of ERK. Among several immediate early gene products, only Jun Band Fra-1 protein levels were increased by LNT, and ginsenoside Rd attenuated Jun Band Fra-1 protein levels induced by LNT. Furthermore, LNT increased AP-1 DNA binding activities, which were partially inhibited by ginsenoside Rd. Our results suggest that ginsenoside Rd exerts an inhibitory action against NO production via blocking phosphorylation of ERK, in turn, suppressing immediate early gene products such as Jun Band Fra-1 in C6 glioma cells.

• Journal of Microbiology and Biotechnology
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• v.26 no.1
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• pp.44-55
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• 2016

Bacillus cereus is a gram-positive, rod-shaped, spore-forming bacterium that has been isolated from contaminated fermented soybean food products and from the environment. B. cereus produces diarrheal and emetic toxins and has caused many outbreaks of foodborne diseases. In this study, we investigated whether B. amyloliquefaciens RD7-7, isolated from rice doenjang (Korean fermented soybean paste), a traditional Korean fermented soybean food, shows antimicrobial activity against B. cereus and regulates its toxin gene expression. B. amyloliquefaciens RD7-7 exhibited strong antibacterial activity against B. cereus and inhibited the expression of B. cereus toxin-related genes (groEL, nheA, nheC, and entFM). We also found that addition of water extracts of soybean and buckwheat soksungjang (Korean fermented soybean paste made in a short time) fermented with B. amyloliquefaciens RD7-7 significantly reduced the growth and toxin expression of B. cereus. These results indicate that B. amyloliquefaciens RD7-7 could be used to control B. cereus growth and toxin production in the fermented soybean food industry. Our findings also provide a basis for the development of candidate biological control agents against B. cereus to improve the safety of fermented soybean food products.

• The Journal of Internal Korean Medicine
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• v.26 no.4
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• pp.776-784
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• 2005

Object : This study aims to assess the efficacy of Sopungsoongiwon(疏風順氣元) in constipated stroke patients and to find out the hepatotoxicity and nephrotoxicity of Sopungsoongiwon. Methods : Subjects were 111 patients who were admitted to tile hospital. The informations about the constipation and other factors were taken through medical records as follows : time until defecation, amount of Sopungsoongiwon until defecation, amount of stool, AST, ALT, BUN, Creatinine. We get the means and standard deviation from the various factors obtained from medical records. Results : 1. The mean time until defecation after taking Sopungsoongiwon was $20.919{\pm}17.885$ hours. 2. The dose of Sopungsoongiwon until defecation was $3.126{\pm}1.624$ packs. 3. The mean amount of stool was $135.360{\pm}63.288g$. 4. AST, ALT, BUN, Creatinine was maintained in normal range after taking sopungsoongiwon(p<0.0001).

• Broadcasting and Media Magazine
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• v.14 no.4
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• pp.26-32
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• 2009

• Korean Architects
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• s.475
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• pp.26-31
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• 2008