• YAKHAK HOEJI
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• v.41 no.3
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• pp.381-388
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• 1997

Metabolism of DWP401, recombinant juman epidermal growth factor, was examined in vivo and in vitro in rats. When $^{125}I$-labeled DWP401 was administered at a dose of 50 ${\mu}g$/kg by i.v. injection. $^{125}I$-labeled DWP401 was rapidly degraded within 30 minytes above 93%. Thin layer chromatography analysis of urine collected for 24 hr after i.v. administration of $^{125}I$-labeled DWP401 showed ohly one spot on a X-ray film which was considered as diiodo-tyrosine. This result suggests tha $^{125}I$-labeled DWP401 was completely digested into free amino acids without any specific intermediate polypeptides. About 42.1% of the administered iodine was recovered in 24 hr. For in vitro degradation study, $^{125}I$-labeled DWP401 was added to plama and tissue homogenates of rats and incubated at $37^{\circ}C$. Almost 98% of the added radioactivity recovered from the protein fraction of the liver, kidey, small intestine, stomach and spleen decreased rapidly. For examplem the recovery rates of $^{125}I$-labeled DWP401 were 58.6, 63.2, 39.9, 52.9 and 66.8% after 4hrs of incubation in respective organ homogenates.

• Journal of Microbiology and Biotechnology
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• v.14 no.2
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• pp.290-296
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• 2004

The effects of potassium, sodium, calcium, magnesium, and iron on cyanobacterial bloom potentials were investigated in Daechung Reservoir, Korea. Potassium showed the highest correlation with the cyanobacterial cell number (r=0.487, P<0.05) and phycocyanin concentration (r=0.499, P<0.05). However, it was not likely that the potassium had directly affected the bloom formation, because the variations of its concentration were not significantly large. In contrast, the Fe concentration fluctuated drastically and exhibited a negative correlation with the cyanobacterial cell number (r=- 0.388, P<0.1) and phycocyanin concentration (r=-0.446, P<0.05). Accordingly, the K:Fe atomic ratio would appear to reflect the extent of cyanobacterial bloom more precisely than K or Fe alone. The K:Fe ratio specifically correlated with cyanobacterial percentage, the cyanobacterial cell number and phycocyanin concentration (r=0.840, P<0.001; r=0.416, P<0.05; r=0.522, P<0.01, respectively). With the K:Fe atomic ratio of over 200, the chlorophyll-a concentration, cyanobacterial cell number, and phycocyanin concentration exceeded $10\mu$g $1^{-1}$20,000 cells $ml^{-1}$, and 20 pM, respectively, the general criteria of eutrophic water.

• Journal of Korean Society of Steel Construction
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• v.15 no.4 s.65
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• pp.379-388
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• 2003

The response of single story buildings and other case studies were investigated to observe trends and develop a better understanding of the impact of some design parameters on the seismic response of Concentrically Braced Frames (CBF). While many parameters are known to influence the behavior of braced frames, the focus of this study was mostly on quantifying energy dissipation in compression and its effectiveness on seismic performance. Based on dynamic analyses of single story braced frame and case studies, a bracing member designed with bigger R and larger KL/r was found to result in lower normalized cumulative energy ratio in both cases.

• International Journal of Advanced Culture Technology
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• v.8 no.4
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• pp.89-94
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• 2020

This study attempted to investigate cognitive load, vividness, and cybersickness in nursing students, in the last year of nursing college, who used a 360-degree video content for studying intravenous fluid infusion, one of the core fundamental nursing skills. The aim was to determine the correlation between the variables, and to decide whether the 360-degree video content can be used as an effective supplementary educational material in the regular curricula. This study, a descriptive research, was conducted from October 31, 2019 to November 14, 2019. The participants in this study were 64 students in the 4th year of nursing college at a university located in B City, South Korea. They were instructed to watch a 360-degree video content for intravenous infusion using a Samsung Head Mounted Display (HMD) while ensuring the safety of the students. The results showed that the scores, out of 7 points, for material design, self-evaluation, and physical effort for cognitive load in nursing students were 5.93±0.71, 5.92±0.71, and 5.64±0.74 points, respectively. In addition, the scores, out of 7 points, for mental effort and task difficulty were 2.55±1.08 and 1.94±0.75 points, respectively, and the scores for vividness and cybersickness in the participants were 5.82±0.84, and 2.57±0.98 points, respectively. Physical effort, self-evaluation, and material design for cognitive load in the participants were positively correlated with vividness (r=.379, r=.458, r=.507). In addition, mental effort for cognitive load was positively correlated with cybersickness (r=.684), whereas self-evaluation and material design were negatively correlated with cybersickness (r=-.388, r=-.343). Based on the results of this study, we believe that the 360-degree video content for intravenous fluid infusion can be used as an educational medium in regular and non-regular curricula. In addition, future studies are needed to specifically develop and verify teaching and learning methods on how to apply 360-degree video contents..

• The Korean Journal of Emergency Medical Services
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• v.12 no.2
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• pp.85-97
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• 2008

Purpose : This study was cross-sectional study to examine the influence of job stress in 119 briefing room workers and aimed to provide the important basic materials for improving working conditions of 119 briefing room workers and further studies. Methods : This study selected 271 workers of 119 briefing room at National Emergency Management Agency and fire stations, metropolitan cities and provinces to examine the influences of job stress of 119 briefing room workers on depression. and as a result of analysis, the following conclusions. Results : 1) The whole average of job stress measure was 3.30. The highest area was interpersonal relationship factor as 3.41, 'job characteristic factor' as 3.36 and communication factor' as 3.01. 2) Total score of whole items of depression was 11.88 and showed slight depression level. 3) There was static correlation between job stress and depression(r=44.7, p= .000). There were statistically significant static correlations between job stress factor and depression(r= .388, p= .000), interpersonal relationship factor and depression(r= .471, p= .000), and communication factor and depression(r= .386, p= .000). 4) There was statistically significant difference in the influence of job stress on depression(B=8.575, p< .001). Influence of job stress on depression was explained as $R^2=.200$. When job stress factors as independent variables were input, interpersonal relationship factor(B=5.062, p< .001) had the greatest influence on depression and there was no statistically significant difference in communication factor(B=2.490, p< .05). Conclusions : It is considered that development of the various programs including program for getting rid of job stress of 119 briefing room workers and counseling program will be needed. particularly, factors such as human relationships and communication in the area of job stress must be the first priority.

• Korean Journal of Pharmacognosy
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• v.32 no.1 s.124
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• pp.55-60
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• 2001

The comparison of $IC_{50}$ values of Salvia plebeia R. Br. extracts on L1210, $P388D_1$ cancer and Vero normal cell lines showed that the n-hexane soluble extract of S. plebeia R. Br. retains the most growth-inhibitory activity against tumor cell lines. The minimum inhibitory concentration (MIC) of the extract against microorganisms were also examined. Antimicrobial activity of amocla and ketoconazole as references was compared to those of other solvent extracts such as $H_2O$, n-hexane, chloroform, ethyl acetate and methanol. The antimicrobial activity of extract had growth inhibition activity against gramnegative bacteria, gram-positive bacteria and fungi $(MIC\;>\;200\;{\mu}g/ml)$ except for n-hexane extract. Seven bacterial strains were tested for in vitro susceptibility to the extract of S. plebeia R. Br. However the n-hexane extract of S. plebeia R. Br. inhibited the growth of several bacterial strains (MIC values between 100 and $200\;{\mu}g/ml$ for gram positive bacteria, $25\;{\mu}g/ml$ for P. putida).

• Korean journal of applied entomology
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• v.22 no.1 s.54
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• pp.7-14
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• 1983

Septoria brown spot closed by Septoria glycines is one of the most serious fungal diseases in soybean. Average yield reduction of 3 varieties for two years was $16.1\%$ by the septoria brown spot inoculation and $9.0\%$ by the natural infection as compared to fungicide-sprayed plots. Number of pods per plant and seed weight were significantly reduced while plant height, number of branches and number of nodes per plant were not affected. Yield reduction was positively correlated to the septoria brown spot severity in all varieties examined. Correlation coefficient $(r=0.38^*)$ between yield reduction and area under the disease progress curve was higher than that (r=0.156) between yield reduction and Van der Plank's apparent infection rate. Potential effect of the septoria brown spot on the soybean yield reduction estimated with the area under the disease progress curve was expressed by the equation of Y=4.38+0.05X $(r=0.0696^*,\;df=25)$.

• Physical Therapy Korea
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• v.30 no.3
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• pp.194-201
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• 2023

Background: Falls are a common and serious problem in the elderly population. Muscle strength and balance are important factors in the prevention of falls. The Y-balance test (YBT) is used to assess dynamic postural control and shows excellent test-retest reliability. However, no studies have examined the relationship between lower-limb strength and YBT scores in elderly women. Objects: This study aimed to examine the relationship between lower-limb strength and YBT scores in elderly women. Methods: Thirty community-dwelling elderly women participated in the study. Lower-limb strength including hip flexor, hip extensor, hip abductor (HAB), hip adductor (HAD), knee flexor, knee extensor, ankle dorsiflexor, and ankle plantar flexor (PF) muscles was examined using a smart KEMA strength sensor (KOREATECH Inc.), and the YBT was used to assess dynamic balance. Relationship between lower-limb strength and YBT was demonstrated using a Pearson's correlation coefficient. Results: HAB strength (r = 0.388, p < 0.05), HAD strength (r = 0.362, p < 0.05), and ankle PF strength (r = 0.391, p < 0.05) positively correlated with the YBT-anterior direction distance. Ankle PF strength was positively correlated with the YBT-posteromedial direction distance (r = 0.396, p < 0.05) and composite score (r = 0.376, p < 0.05). Conclusion: The results of this study suggest that HAB, HAD, and ankle PF strengths should be considered for dynamic postural control in elderly women.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2010.06a
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• pp.388-388
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• 2010

In this study, Ferroelectric vinylidene fluoride-trifluoroethylene (VF2-TrFE) copolymer films were directly deposited on degenerated Si (n+, $0.002\;{\Omega}{\cdot}cm$) using by spin coating method. A 1~5 wt% diluted solution of purified vinylidene fluoride-trifluoroethylene (VF2:TrFE = 70:30) in a dimethylformamide (DMF) solvent were prepared and deposited on silicon wafers at a spin rate of 2000 ~ 4000 rpm for 2 ~ 30 seconds. After annealing in a vacuum ambient at 100 ~ $200^{\circ}C$ for 60 min, upper aluminum electrodes were deposited by vacuum evaporation for electrical measurement. X-ray diffraction results showed that the VF2-TrFE films on Si substrates had $\beta$-phase of copolymer structures. The capacitance on highly doped Si wafer showed hysteresis behavior like a butterfly shape and this result indicates clearly that the copolymer films have ferroelectric properties. The typical measured remnant polarization ($P_r$) and coercive filed ($E_c$) values were about $5.7\;{\mu}C/cm^2$ and 710 kV/em, respectively, in an applied electric field of ${\pm}$ 1.5 MV/em. The gate leakage current densities measured at room temperature was less than $7{\times}10^{-7}\; A/cm^2$ under a field of 1 MV/cm.

• Korean Journal of Environmental Agriculture
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• v.25 no.3
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• pp.211-216
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• 2006

The present research was undertaken to investigate the activities of ligninolytic enzymes and dye-decolorization capabilities of white-rotting fungi Coriolus hirsutus LD-1. The isolated white-rotting fungi (Coriolus hirsutus LD-1) produced laccase (16,388.9 U/L) and manganese-dependent peroxidase (19.81 U/L) but it did not produce lignin peroxidase. When the isolated fungi was incubated with the treatment of dyes for 8 days, the rates of decolorization of remazol brilliant blue R and bromophenol blue were 70.2% and 98%, respectively. The activity for manganese-dependent peroxidase was low, whereas that for laccase was very high. Moreover, the laccase was more effective to decolor when compared to manganese-dependent peroxidase. The results suggested that laccase of Coriolus hirsutus LD-1 might be playing an important role in the decolorization of the dyes.