• Title/Summary/Keyword: R-Factor

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Eudesmin Inhibits Tumor Necrosis Factor-$\alpha$ Production and T cell Proliferation

  • Cho, Jae-Youl;Yoo, Eun-Sook;Baik, Kyoung-Up;Park, Myung-Hwan
    • Archives of Pharmacal Research
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    • v.22 no.4
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    • pp.348-353
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    • 1999
  • Possible antiinflammatory effect of eudesmin were examined by assessing the effects on tumor necrosis factor (TNF)-$\alpha$ production and lymphocyte proliferation as well as cytotoxicity against murine and human macrophages. the compound significantly inhibited TNF-$\alpha$, production by lipopolysaccaride (LPS)-stimulated murine macrophage RAW264.7 without displaying cytotoxicity suggesting that eudesmin may inhibit TNF-$\alpha$ production without any interference of normal cell function. It also significantly attenuated T cell proliferation stimulated by concanavalin A (Con A) in a dose-dependent manner.

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The Effect of Physical Environment of Family Restaurants on Customers' Satisfaction (패밀리 레스토랑의 물리적 환경이 고객만족에 미치는 영향)

  • Kim, Ki-Young;Kim, Sung-Su;Cheon, Hee-Sook
    • Culinary science and hospitality research
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    • v.13 no.2
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    • pp.22-34
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    • 2007
  • We researched the previous study about the restaurant's physical environment and had made up questionnaires. The purpose of this study is to analyze the effect of physical facilities of family restaurants on customers' satisfaction. The result was as follows: First, customers visited with friends or family irrespective of days $2{\sim}3$ times a month. Second, the physical environment factors of family restaurants were interior design, interior, making atmosphere and exterior. Third, it was the interior factor(0.268), making atmosphere factor(0.353) and exterior factor(0.244) that affected customers' satisfaction in family restaurants(p<0.001). $R^2$ change was 0.659 and the regression model was suited to our study(F=56.475). To increase customers' satisfaction, the physical environment of family restaurants needs remodeling in proper time.

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A Study of Gage R&R Analysis Considering the Variations of Between-Within Group and Within Part (군간-군내-부품내 변동을 고려한 Gage R&R 분석에 관한 연구)

  • Lee, Seung-Hoon;Lee, Chang-Woo
    • IE interfaces
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    • v.18 no.4
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    • pp.444-453
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    • 2005
  • The purpose of the Gage R&R study is to determine whether a measurement system is adequate for monitoring a process. If the measurement system variation is small relative to the process variation, then the measurement system is deemed "adequate". The sources of variation associated with the measurement system are compared using an analysis of variance (ANOVA) model, in general. A typical ANOVA model used in a standard Gage R&R study is the two-factor random effect model. Then, the ANOVA partitions the total variation into three categories: repeatability, reproducibility, part variation. However, if the process variation possesses the between group variation, within group variation, and within part variation, these variations can cause the measurement system evaluation to provide misleading results. That is, in the standard Gage R&R study these variations affect the estimate of repeatability, reproducibility, or both. This paper presents a four-factor nested factorial ANOVA model which explicitly considers these variations for the Gage R&R study. The variance component estimators are derived by setting the EMS equations equal to the corresponding mean square from the ANOVA table and solving. And the proposed model is compared with the standard Gage R&R model.

A Study on Determinant Factors of Foreign Firm's R&D Investment Scale in Korean Market (국내진출 해외기업들의 R&D관련 투자규모 결정요인에 관한 연구)

  • Choi, Soon-Gwon
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.38
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    • pp.377-408
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    • 2008
  • Globalization of R&D activities of multinational firms is becoming important in compared with the past, because of increasing globalization of world economy. So, every country tries to attract foreign investment including R&D activities. In this paper, effects of several factors, which determine the scale of foreign subsidiary's R&D activities in local market, are analyzed. Through the review of previous literature, I found that three groups of determinant factors. The first one is the factor which is related to characteristics of local market, such as competitive situation of local market, accessability to research institutions, etc. The second group is the factor which is related to relationship between foreign subsidiary and its mother company. The dominant factors of this group are operation strategy of foreign subsidiary, competitiveness of mother firm, and equity structure of foreign subsidiary. Finally the characteristics of industry affect to the scale of foreign subsidiary's R&D activities. Among these factors, 6 factors are chosen to investigate empirically. For the empirical investigation, 107 foreign subsidiaries among KOITA(Korea Industrial Technology Association)'s list are chosen. Each subsidiary has more than 50% of foreign equity and implement R&D activities in Korea. The results show that sales volume of foreign subsidiary is dominant influencing factor in determining scale of R&D activities in Korean market. And also I found that currently established firms are implementing more R&D activities than old established firms. This is quite interesting finding. However, R&D activities of foreign subsidiary are not vitalized in Korean market. It probably means that Korean government and Korean business partners have to make effort to enhance foreign firms/ R&D activities, because it could contribute technological and economic development of Korean market.

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Liquid Velocity and Local Fouling in Coagulation-submerged Microfiltration Module for Drinking Water Treatment (정수처리를 위한 응집-침지식 정밀여과 모듈의 유체유속 및 국부오염)

  • Choi, Youngkeun;Kim, Hyun-Chul;Noh, Soohong
    • Membrane Journal
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    • v.25 no.3
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    • pp.268-275
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    • 2015
  • Effects of aeration intensity on local fouling were investigated in submerged membrane modules. Higher liquid velocities were observed at the section with the lower fiber packing density. The liquid velocity is increased with increasing the gas-liquid injection factor. The high shear stress coincided with the high liquid velocity. The shear stress increases with the increasing of gas-liquid injection factor and the liquid velocity improves with the increasing of gas-liquid injection factor. Irreversible fouling resistance ($R_{ir}$) of the fiber position is significant in a local region of high suction pressure near the suction point of the fiber (position 1). The ratio of $R_{ir}/R_m$ and $R_{ir}/R_r$ of position 1 was highest compared to the position 2 and 3. Irreversible fouling resistances results confirmed the preferential deposition of foulants near the suction part of the fiber where the local suction pressure is the highest and correspondingly, more particles are accumulated to the membrane surface. The effects of local fouling along the fiber length are significant factors to optimize the design of submerged modules.

The structure analysis of $Y_1Ba_2Cu_3O_x$ high Tc superconductor based on rietveld method (리트벨트 해석법을 이용한 $Y_1Ba_2Cu_3O_x$ 고온 초전도체의 구조분석)

  • 채기병;소대화
    • Electrical & Electronic Materials
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    • v.8 no.6
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    • pp.780-786
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    • 1995
  • For the execution of RIETAN program adopting Rietveld Analysis Method, the sample superconductor is made according to the solid state synthesis method at 920.deg. C for 24hrs, and was examined for the optimization of parameters needed to analyze Rietveld method with the input of the measured pattern data after measuring the pattern resulted from the X-ray diffraction. It was proven that the lattice constant of the superconductor which was consisted of Pmmm orthorhombic crystal structure in the analyzed space group correspond to the presented theoretical lattice constant a=3.8887(8).angs., b=3.8238(4).angs., c=11.7079.angs.. Therefore, it was examined and confin-ned that the R factor, which was compensated after analyzing the structure of superconductor resulted from this experimented data with the computer simulation, was refined to $R_{wp}$=8.83[%], $R_{P}$=6.47[%], $R_{I}$=10.08[%], $R_{F}$=7.19[%], $R_{E}$=3.76[%]. On the basis of these experimental data, the significant parameter such as the scale factor(S) and the zero point shift(Z) and FWHM value(U,V,W) were optimized as follows; S=2.0827E-3, Z=0.2146, U=4.2761E-2, V=1.7983E-2, and W=2.6768E-2.2.2.2.2.2.

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Comparison of Threshold Stress Intensity Factor and Fatigue Limit for Micro-crack of Offshore Structural Steel F690

  • Gu, Kyoung-Hee;Lee, Gum-Hwa;Lee, Weon-Gu;Oh, Chang-Seok;Nam, Ki-Woo
    • Journal of the Korean Society of Industry Convergence
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    • v.25 no.2_1
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    • pp.141-148
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    • 2022
  • In this paper, the evaluation equations proposed by Tange et al. and Ando et al. were used to evaluate the threshold stress intensity factor ∆KRth(s) and fatigue limit ∆𝜎Rwc, according to the small crack of offshore structural steel F690. Despite the differences in concept and shape of the two equations, the ∆KRth(s) and ∆𝜎Rwc proved completely consistent. It is possible to use these equations to evaluate the dependence of the crack length on the ∆KRth(s) and ∆𝜎Rwc of structures made of all steel grades. With these equations, the characteristics of microcracks can be quantitatively evaluated, and the safety and reliability of the structure can be secured.

Reliability analysis of piles based on proof vertical static load test

  • Dong, Xiaole;Tan, Xiaohui;Lin, Xin;Zhang, Xuejuan;Hou, Xiaoliang;Wu, Daoxiang
    • Geomechanics and Engineering
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    • v.29 no.5
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    • pp.487-496
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    • 2022
  • Most of the pile's vertical static load tests in construction sites are the proof load tests, which is difficult to accurately estimate the ultimate bearing capacity and analyze the reliability of piles. Therefore, a reliability analysis method based on the proof load-settlement (Q-s) data is proposed in this study. In this proposed method, a simple ultimate limit state function based on the hyperbolic model is established, where the random variables of reliability analysis include the model factor of the ultimate bearing capacity and the fitting parameters of the hyperbolic model. The model factor M = RuR / RuP is calculated based on the available destructive Q-s data, where the real value of the ultimate bearing capacity (RuR) is obtained by the complete destructive Q-s data; the predicted value of the ultimate bearing capacity (RuP) is obtained by the proof Q-s data, a part of the available destructive Q-s data, that before the predetermined load determined by the pile test report. The results demonstrate that the proposed method can easy and effectively perform the reliability analysis based on the proof Q-s data.

Study on the Prediction of Pressure Drop for Alternative Refrigerants with lubricant in Micro-Fin Tubes (미세휜관내 윤활유를 포함한 대체냉매의 압력강하 예측에 관한 연구)

  • Choi, Jun-Y.;Lee, Jin-Ho
    • Proceedings of the KSME Conference
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    • 2000.04b
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    • pp.83-89
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    • 2000
  • This paper presents a pressure drop correlation for evaporation and condensation of alternative refrigerant with oil in micro-fin tubes. The correlation was developed from a data base consisting of oil-free pure and mixed refrigerants in micro-fin tube; Rl25 R134a. R32 R410a(R32/R125 50/50% mass), R22, R407c(R32/R125/R134a, 23/25/52% mass) and R32/R134a(25/75% mass). The micro-fin tube used in this paper had 60 0.2mm high fins with a 18 helix angle. The cross sectional flow area $(A_c)$ was $60.8 mm^2$ giving an equivalent smooth diameter$(D_e)$ of 8.8mm. The hydraulic diameter $(D_h)$ was estimated to the 5.45mm. The new correlation was obtained by replacing the friction factor and the tube-diameter in Bo Pierre correlation by a friction factor derived from pressure drop data for a micro-fin tube and the hydraulic diameter, respectively. This correlation was also used to predict some pressure data with a lubricant after using a mixing viscosity rule of lubricants and refrigerants. As a result, the new correlation was also well predicted to the measured data within a mean deviation of 19.0%.

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Derivations of Buckling Knockdown Factors for Composite Cylinders Considering Various Shell Thickness Ratios and Slenderness Ratios (다양한 두께비와 세장비를 고려한 복합재 원통 구조의 좌굴 Knockdown factor의 도출)

  • Kim, Do-Young;Sim, Chang-Hoon;Kim, Han-Il;Park, Jae-Sang;Yoo, Joon-Tae;Yoon, Young-Ha;Lee, Keejoo
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.49 no.4
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    • pp.321-328
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    • 2021
  • This paper derives numerically new buckling Knockdown factors for the lightweight design of the composite propellant tanks for space launch vehicles. A nonlinear finite element analysis code, ABAQUS, is used for the present postbuckling analysis of composite cylinders under compressive loads. Various thickness ratios (R/t) and slenderness ratios (L/R) are considered and Single Perturbation Load Approach is applied to represent the geometric initial imperfection of the composite cylinder. For the composite cylinder with thickness ratio of 500 and slenderness ratio of 2.04, the buckling Knockdown factor derived in this work is higher by 84.38% than NASA's previous buckling design criteria. Therefore, it is investigated that a lightweight design is possible when the present Knockdown factors are used for the design of composite propellant tanks. In addition, it is shown that global buckling loads and buckling Knockdown factors decrease as the thickness ratio or slenderness ratio of composite cylinders increases.