• Title/Summary/Keyword: R&D industry

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Antimutagenic and Cytotoxic Effects of an Ethanol Extract of Buckwheat Sprout (메밀싹 에탄올 추출물의 항돌연변이원성 및 암세포 성장억제 효과)

  • Cui, Cheng-Bi;Lee, Eui-Yong;Ham, Seung-Shi;Lee, Deuk-Sik
    • Applied Biological Chemistry
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    • v.51 no.3
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    • pp.212-218
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    • 2008
  • This study was performed to determine the antimutagenic and anticancer effects of ethanol extract of buckwheat sprout using Ames test and SRB assay, respectively. An ethyl acetate fraction (200 ${\mu}/plate$) from the ethanol extract of buckwheat sprout showed inhibition rate of 80.6% against the mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Salmonella typhimurium TA100 strain. Also the ethyl acetate fraction (200 ${\mu}/plate$) showed higher antimutagenic activity than other fractions against the mutagenesis induced by 4-nitroquinoline-1-oxide (4NQO) in Salmonella typhimurium TA98 and TA100. In addition, the ethyl acetate fraction (200 ${\mu}/plate$) showed high antimutagenic effect of 80.9% and 85.9% against the mutation of TA98 and TA100 strains induced by 3-amino-1,4-dimethyl-5H-pyrido-(4,3-b)indol (Trp-P-1), respectively. The cytotoxic effects of each solvent fraction from the ethanol extract of buckwheat sprout against human cancer cell lines including lung carcinoma (A549), gastric carcinoma (AGS), breast adenocarcinoma (MCF-7), hepatocellular carcinoma (Hep3B), and colon adenocarcinoma (Colo 205) were investigated. The ethyl acetate fraction of buckwheat sprout ethanol extract at the concentration of 1.0 mg/ml showed strong cytotoxic activities of 70.3, 94.8, 79.6, 82.3, and 73.2% against A549, AGS, MCF-7, Hep3B and Colo 205 cancer cell lines, respectively.

A Relative Importance Evaluation of Shipbroking Service by the AHP (AHP 분석을 이용한 해운중개 서비스의 상대적 중요도 평가)

  • Kim, Hwa Young;Kim, Un Soo
    • Journal of Korea Port Economic Association
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    • v.29 no.4
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    • pp.157-174
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    • 2013
  • A shipbroking is maritime service business, which is consist of market of freight, shipbuilding, sales & purchase and demolition for intermediation between customer and supplier. In this way, a shipbroking business has strong relationship with shipping industry and is also knowledge service business for creation additional value based on shipping, shipbuilding, financial and law etc. However, the research on the evaluation items and a method for shipbroking company were not carried out in previous research. In this paper, We defined evaluation items with three high level, six middle level and sixteen low level for evaluation of shipbroking service by expert's brainstorming and AHP(analytic hierarchy process) method. And also carried out survey to employees of shipbroking company as supplier and shipping company as customer. As a result of survey, result of service in high level, convenient of middle level and credibility of low level are evaluated highly, and also business credit rating, profit of customer, achievement of customer's object are considered to more important than others items. In case of comparison between group, a method of contact with client, problem-solving ability, good relationship with clients of international and domestic evaluated importantly in common.

A Study on the compensation regime and response cost for oil pollution in Korea and advanced country (선진국과 우리나라의 유류오염 방제비용 및 피해보상제도에 관한 연구)

  • Kim, Du-Ho;Im, Taek-Soo;Na, Eun-Young;Kim, Han-Gyu
    • Proceedings of KOSOMES biannual meeting
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    • 2006.11a
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    • pp.175-179
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    • 2006
  • With the rapid development of oil and chemical industry in the late 20C, massive transportation of oil by oil tanker vessel has grown and it caused the big oil pollution accidents. When oil spill from the oil tanker, damages reach into the astronomical figures in economically and damages affect wide area and many people with break the balance of ecosystem. Recently in Korea, the oil pollution accidents has occurred frequently as growing of oil consumption and it caused large-scale damages to the victim. Oil pollution in Korean offshore takes not only korean fishermen from their life ground and break the ecosystem but it takes too much time and money to recover. To minimize oil pollution damages, it is necessary to make pre-caution effort as a ship owner and relevant government bodies should endeavor to prevent from more damages. But once oil pollution accidents occurs in territorial sea, compensation for victim fishermen is very important. But it is true that compensation is not paid to victim smoothly. So this study aims at the problems of oil pollution compensation to the Korean victim and find the best way to get reasonable compensation.

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Decision Algorithm of Natural Algae Coagulant Dose to Control Algae from the Influent of Water Works (정수장 유입조류 전처리를 위한 천연조류제거제(W.H.)의 최적주입농도 결정)

  • Jang, Yeo-Ju;Jung, Jin-Hong;Lim, Hyun-Man;Yoon, Young H.;Ahn, Kwang-Ho;Chang, Hyang-Youn;Kim, Weon-Jae
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.9
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    • pp.482-496
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    • 2016
  • Algal blooms of cyanobacteria (blue-green Algae) due to the eutrophication of rivers and lakes can cause not only the damage by its biological toxins but also the economic loss in drinking water treatment. The natural algae coagulant, a commercial product known as W.H. containing the algicidal and allelopathic material derived from oak, can control algal problems proactively through the coagulation flotation process. However, because there have been no applications of the process for pre-treatment in drinking water plants, we could find no report on the optimum injection dose of W.H.. In this study, we have conducted several sets of jar-tests while changing W.H. dose and concentration of chl-a for (1) Han-river samples and (2) subcultured cyanobacteria samples, and monitored the removal mechanisms of algae intensively. Based on these jar-test results, two linear equations with variables of chl-a and turbidity have been deduced to predict the optimal W.H. dose after the multiple regression analysis using IBM-SPSS. Also, prototypes of automatic control logic have been suggested to inject the optimal W.H. dose promptly in response to the variation of water quality.

Causal Links from Innovative Activities to Financial Performance in Korean Manufacturing Firms: Mediating Effects of Innovative and Operational Performance (한국 제조업에서 혁신활동과 재무적 성과 간의 인과경로: 혁신성과 및 운영성과의 매개효과를 중심으로)

  • Kim, KonShik
    • Journal of Korea Technology Innovation Society
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    • v.17 no.1
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    • pp.146-173
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    • 2014
  • Extant studies have explained that firm's innovations including technological product and process innovations contribute to its competitive advantage and growth, thereby supporting competitiveness and growth of industry. These studies, however, have focused mainly on the role and effect of technological change that is primarily measured by the patent numbers and R&D intensity. Aside from these traditional streams, there has been growing interest on the impact by various dimensions of innovation including non-technological innovations. Apart from the discussions on the dimensions and scope of innovation, stages or processes of innovation also have been studied. Extant studies on innovation process model, however, has limited its interests in the structure of the transformation of knowledge. This study have established a comprehensive model embracing operational and financial performance to investigate the causal paths between innovation and firm performance. Using multi-level generalized linear model with path analysis, this study have found results as follows: First, the processes from innovative activities to innovation output and outcomes including operational and financial performance at firm level were verified. Secondly, the influence of innovation decreases gradually as the distance away from the direct outputs of the innovation increase in the direction of financial outcomes. Third, the effect of innovation on the sales growth rate is higher for small businesses than for medium-sized businesses. The effect of innovation on the profit rate, however, is significant only for medium-sized businesses. For large businesses, innovation has no positive significant impact on any financial performance at all. Fourth, Fourth, the appropriability of innovation has positive impacts on innovative performance, patent applications, and operational performance.

Comparison between Planned and Actual Data of Block Assembly Process using Process Mining in Shipyards (조선 산업에서 프로세스 마이닝을 이용한 블록 조립 프로세스의 계획 및 실적 비교 분석)

  • Lee, Dongha;Park, Jae Hun;Bae, Hyerim
    • The Journal of Society for e-Business Studies
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    • v.18 no.4
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    • pp.145-167
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    • 2013
  • This paper proposes a method to compare planned processes with actual processes of bock assembly operations in shipbuilding industry. Process models can be discovered using the process mining techniques both for planned and actual log data. The comparison between planned and actual process is focused in this paper. The analysis procedure consists of five steps : 1) data pre-processing, 2) definition of analysis level, 3) clustering of assembly bocks, 4) discovery of process model per cluster, and 5) comparison between planned and actual processes per cluster. In step 5, it is proposed to compare those processes by the several perspectives such as process model, task, process instance and fitness. For each perspective, we also defined comparison factors. Especially, in the fitness perspective, cross fitness is proposed and analyzed by the quantity of fitness between the discovered process model by own data and the other data(for example, the fitness of planned model to actual data, and the fitness of actual model to planned data). The effectiveness of the proposed methods was verified in a case study using planned data of block assembly planning system (BAPS) and actual data generated from block assembly monitoring system (BAMS) of a top ranked shipbuilding company in Korea.

A study on standardization and R&D strategies of agrifood-ICT convergence technology (농식품-ICT 융·복합 기술 개발 및 표준화 추진방향)

  • Min, J.H.;Huh, M.Y.;Park, J.Y.
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.05a
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    • pp.777-780
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    • 2015
  • Currently, our country has promoted sustainable growth in agriculture field by expanding the growth engine which is going to creat new value through agrifood industry & ICT convergence, the deployment of computerization in rural areas and the efficiency increase of agricultural administration system. Since the level of domestic agriculture-ICT convergence technology focusing on production areas is at early stage, it is necessary to deploy the successful models through the systematic development of technology and standardization including production, distribution and consumption phase. In addition, because the management and control systems of large glass greenhouse are mostly foreign products with no standardization and related small domestic companies, there is a limit to agri-food & ICT convergence activation led by the agri-food private sector. Also, it is vital to increase productivity & efficiency and improve quality throughout the entire agricultural process including production, distribution and consumption by the fusion of information technology, automatic control technology and unique ICT on existing agricultural technology, Therefore, in this paper we propose the agricultural-ICT convergence technology fields in which our country can lead technology and the standardization plans through analyzing the development, policy and standardization trends on agricultural-ICT convergence technology.

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Feasibility of Mineral Carbonation Technology as a $CD_{2}$ Storage Measure Considering Domestic Industrial Environment (국내 산업 여건을 고려한 $CD_{2}$ 저장 방안으로서 광물 탄산화 기술의 타당성)

  • Han, Kun-Woo;Rhee, Chang-Houn;Chun, Hee-Dong
    • Korean Chemical Engineering Research
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    • v.49 no.2
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    • pp.137-150
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    • 2011
  • $CO_{2}$ mineral carbonation technology, fixation technology of $CO_{2}$ as carbonates, is considered to be an alternative to the $CO_{2}$ geological storage technology, which can perform small- or medium-scale $CO_{2}$ storage. We provide the current R&D status of the mineral carbonation with special emphasis on the technical and economical feasibility of $CO_{2}$ mineral carbonation taken into consideration of the domestic geological and industrial environment. Given that the domestic industry produces relatively large amount of the industrial by-products, it is expected that the technology play a pivotal role on the $CO_{2}$ reduction countermeasure, reaching the potential storage capacity to 12Mt-$CO_{2}$/yr. The economics of the overall process should be improved via the development of advanced technologies on the pretreatment of raw materials, method/solvents for metal extraction, enhanced kinetics of carbonation reactions, heat integration, and the production of highly value-added carbonates.

Determination of Optimum Sterilization Condition for the Production of Retorted Kimchi Soup (레토르트 처리한 김치찌개 제품의 최적 살균조건 결정)

  • Cheon, Hee Soon;Park, Eun-Ji;Cho, Won-Il;Hwang, Keum Taek;Chung, Myong-Soo;Choi, Jun-Bong
    • Culinary science and hospitality research
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    • v.20 no.6
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    • pp.254-261
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    • 2014
  • In order to optimize process conditions for manufacturing retorted Kimchi soup by using stationary and rotary types systems were applied for sterilization process. For investigating the differences in heat penetration characteristics during sterilization, Kimchi soup was packed into retort pouches, and sterility ($F_0$ value) at various positions in the product was measured through a wireless $F_0$ sensor. Heat penetration characteristics were significantly affected by sterilization method. From data analysis, optimum ranges of sterilization temperature and time was determined to be $120.7^{\circ}C$, 13 min for rotary type and $120.7^{\circ}C$, 20 min for stationary type. At those conditions, they had similar sterility ($F_0$ value). The results showed that rotation provides faster heat penetration and more uniform sterility than various positions of the product. These results derived a lot of advantages from related industry. For instance, many of the more viscous semi-liquid products and heat sensitive natural products could be sterilized in the lager pouch sizes without overcooking or scorching. Hence, current study suggests that rotary type retort would make it possible not only to reduce processing times as 35~45%, but also to improve the quality of product as overall taste, flavor, color, and texture with significant difference (p<0.05).

Research on the Relative Importance and the Priority for the Functions of the U-City Service Aid Organization (U-City 서비스 지원기관 기능의 상대적 중요도와 우선순위 연구)

  • Yi, Mi Sook;Shin, Dong Bin;Lee, Jae Yong
    • Spatial Information Research
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    • v.21 no.2
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    • pp.35-43
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    • 2013
  • The aim of this research is to analyze the priority to functions of the U-city Service Aid Organization(USAO), which is to support invigorating U-City industry. This research analyzes the relative importance and the priority about the functional area and components of UASO based on AHP. This research also performs a sensitivity analysis. The research result shows that relative importance of functional area is like following orders: 1) distribution of U-City service-related information, 2) quality certification of U-City-related products and services, 3) R&D of U-City technology, 4) standardization of U-City, 5) U-City human resource development. The relative importance order of functional components is 1) establishment of U-City information distribution organization, 2) construction and management of U-City information distribution network, 3) supporting U-City information distribution and price policy, 4) providing U-City information list for distribution, 5) preparation and application of quality certification standard of U-City products and services, 6) research on legal system of U-City items, targets, and procedures for quality certification, 7) research, analysis, and provision of U-City information distribution situation, 8) level examination of constructed infrastructures and services in U-City, 9) U-City core technology development and localization of technology, 10) standardization of collected U-City information, service classification, distribution system. This research result can be applied directly to design functions of USAO. The result also can be used for duty management, human resource planning, or resource allocation.