• Title/Summary/Keyword: Pure lead

Search Result 175, Processing Time 0.023 seconds

The Effects of Daily Melatonin Gavage on Reproductive Activity in the Male Syrian Hamsters

  • Jeon, Geon Hyung;Kim, Hyeon Jeong;Park, Jinsoo;Lee, Sung-Ho;Cheon, Yong-Pil;Choi, Donchan
    • Development and Reproduction
    • /
    • v.24 no.4
    • /
    • pp.263-275
    • /
    • 2020
  • The proper administration of melatonin has well been documented to induce testicular regression in seasonal breeding animals. The subcutaneous injections of melatonin in the afternoon, not in the morning, consistently occurred testicular involution in the male Syrian (golden) hamsters whose reproductive activity is regulated by the photoperiod. But the effects of daily melatonin via gavage have not been estimated. Golden hamsters housed in long photoperiod (LP) were divided into 5 groups: the control animals housed in LP or in short photoperiod (SP) and animals treated daily with low (15 ㎍), middle (150 ㎍), and high dosages (1,500 ㎍) of pure melatonin by using gavage in the evening for 8 weeks. As results, LP control animals had large testes and SP controls displayed small and entirely regressed testes. The animals treated with various dosages of melatonin showed collectively degenerating effects on the weights of testes, epididymides, and seminal vesicles in the middle and high dosage groups, with the individual differences as well. The high dosages induced testicular regression in more proportion than the middle dosages did. The low dosage had large testes like the LP control animals. The small and inactive testes shown in some animals of both middle and high groups presented the complete regression as those of the animals maintained in SP. These results strongly suggest that the administrations of melatonin lead to testicular involution in the male golden hamsters when it is administered through gavage.

Effect of Heat and Moisture on the Phase Transition in Dimethylammonium-Facilitated CsPbI3 Perovskite (다이메틸암모늄 유도 CsPbI3 페로브스카이트 상의 상전이 거동에 대한 열과 수분의 영향)

  • Sohyun Kang;Seungmin Lee;Jun Hong Noh
    • Korean Journal of Materials Research
    • /
    • v.33 no.8
    • /
    • pp.344-351
    • /
    • 2023
  • Cesium lead iodide (CsPbI3) with a bandgap of ~1.7 eV is an attractive material for use as a wide-gap perovskite in tandem perovskite solar cells due to its single halide component, which is capable of inhibiting halide segregation. However, phase transition into a photo inactive δ-CsPbI3 at room temperature significantly hinders performance and stability. Thus, maintaining the photo-active phase is a key challenge because it determines the reliability of the tandem device. The dimethylammonium (DMA)-facilitated CsPbI3, widely used to fabricate CsPbI3, exhibits different phase transition behaviors than pure CsPbI3. Here, we experimentally investigated the phase behavior of DMA-facilitated CsPbI3 when exposed to external factors, such as heat and moisture. In DMA-facilitated CsPbI3 films, the phase transition involving degradation was observed to begin at a temperature of 150 ℃ and a relative humidity of 65 %, which is presumed to be related to the sublimation of DMA. Forming a closed system to inhibit the sublimation of DMA significantly improved the phase transition under the same conditions. These results indicate that management of DMA is a crucial factor in maintaining the photo-active phase and implies that when employing DMA designs are necessary to ensure phase stability in DMA-facilitated CsPbI3 devices.

A Study on the Theories of Ideal Society in Daesoonjinrihoe (대순진리회의 이상사회론 연구)

  • Na, Kwon-soo
    • Journal of the Daesoon Academy of Sciences
    • /
    • v.21
    • /
    • pp.409-452
    • /
    • 2013
  • This paper aims to cast light on the theoretical characteristics of Korean new religions' utopian theory from the perspective of theology and apply the findings to the utopian theory of the new religions in Korea. The utopian theory of the new religions in Korea occurred to meet people's aspiration towards a new world on the background of the national ordeal and its consequential psychology in the late Chosun dynasty. As a result, it has the characteristics of a shift from a pure religious framework to participation in reality to realize religious ideals 'right here, right now'. Thus, it basically defined an utopian theory as the product of a society and history, and explained the utopian theory as the projection of the thoughts about current conflicts. However, an approach in this way may leave the likelihood that the individual characteristics of Daesoonjinrihoe would be overlooked and the utopian theory would be limited to the byproduct of the age, only. Thus, this paper has dealt with the religious experience of the founders as the lead of discussion, not a sociological approach. In this context, the religious experience of founders can be more significant clues to view the characteristics of an utopian theory. This directivity of a study can be understood as an attempt to improve the previous sociological methodologies, the leading discourses, and to contribute to the different perspectives on an understanding of the utopian theories of Daesoonjinrihoe. Furthermore, this paper is anticipated to give salience to the individual characteristics reflected in the new religions in Korea and to enhance its status in the history of thoughts, not as the trend of the thought limited to the past.

Effect of Transition Metal Ion on the Reaction of Benzylbromide with Grignard Reagent (Grignard 시약과 브로모벤질과의 반응에서 첨가전이 금속이온의 영향 연구)

  • Jack C. Kim;Young-Sim Koh;Ung-Chan Yoon;Min-Sook Kim
    • Journal of the Korean Chemical Society
    • /
    • v.37 no.2
    • /
    • pp.228-236
    • /
    • 1993
  • The effect of ferric ion on the reaction of CH_3$MgI with benzylbromide was investigated by determining the product ratio between cross-coupling product, ethylbenzene (A) and homocoupling product, bibenzyl (B) in the presence of ferric ion. When CH_3$MgI prepared with pure magnesium was used, the ratio of A to B was 22 to 78 and with reagent grade magnesium, the ratio became 33 to 67 indicating that metallic impurities in magnesium affect the reaction mechanism to lead less homocoupling product, B. The ratio changes became significant when ferric chloride was added in the reaction mixture in catalytic amounts and the ratio of A to B reached to 80 to 20 at maximum. The reaction in the presence of ferric ion seems to follow mainly an ionic mechanism which involves iron-benzyl bromide ${\pi}$-complex formation. The complex formation is expected to be able to enhance ionic attack of CH_3$MgI on benzyl carbon to give more A.

  • PDF

Development of a Computation Code for the Verification of the Vulnerability Criteria for Surf-riding and Broaching Mode of IMO Second-Generation Intact Stability Criteria (IMO 2세대 선박 복원성 기준에 따른 서프라이딩/ 브로칭 취약성 기준 검증을 위한 계산 코드 개발)

  • Shin, Dong Min;Oh, Kyoung-gun;Moon, Byung Young
    • Journal of Ocean Engineering and Technology
    • /
    • v.33 no.6
    • /
    • pp.518-525
    • /
    • 2019
  • Recently, the Sub-Committee on SDC (Ship Design and Construction) of IMO have discussed actively the technical issues associated with the second-generation intact stability criteria of ships. Generally, second generation intact stability criteria refer to vulnerability five modes ship stability which occurs when the ship navigating in rough seas. As waves passes the ship, dynamic roll motion phenomenon will affect ship stability that may lead to capsizing. Multi-tiered approach for second generation of intact stability criteria of IMO instruments covers apply for all ships. Each ship is checked for vulnerability to pure loss of stability, parametric roll, and broaching/surf-riding phenomena using L1(level 1) vulnerability criteria. If a possible vulnerability is detected, then the L2(level 2) criteria is used, followed by direct stability assessment, if necessary. In this study, we propose a new method to verify the criteria of the surf-riding/broaching mode of small ships. In case, L1 vulnerability criteria is not satisfied based on the relatively simple calculation using the Froude number, we presented the calculation code for the L2 criteria considering the hydrodynamics in waves to perform the more complicated calculation. Then the vulnerability criteria were reviewed based on the data for a given ship. The value of C, which is the probability of the vulnerability criteria for surf-riding/broaching, was calculated. The criteria value C is considered in new approach method using the Froude-Krylov force and the diffraction force. The result shows lower values when considering both the Froude-rylov force and the diffraction force than with only the Froude-Krylov force was considered. This difference means that when dynamic roll motion of ship, more exact wave force needs considered for second generation intact stability criteria This result will contribute to basic ship design process according to the IMO Second-Generation Intact Stability Criteria.

Study on the Manufacturing Techniques of Metallic Ornament of Treasure 930, the Staffs of Yi Gyeong-seok (보물 제930호 이경석 지팡이에 사용된 장석의 제작기법 고찰)

  • Lee, Jae-sung;Jeon, Ik-hwan
    • Journal of Conservation Science
    • /
    • v.31 no.3
    • /
    • pp.309-318
    • /
    • 2015
  • The staff given with chair to Yi Gyeong-seok, senior official over 70 years old by King Hyeonjong of Joseon Dynasty is representative handcraft of Joseon Dynasty. Results of analysis on the metallic decoration show that the metallic ornament of the end part which is connected to the spade was made by rolling of iron plate and brass plating. The plated part is limited to the ornament of the end part connected to the spade and the plating was not applied to the spade. Brass including 20% zinc was used for the connecting part of guard while brass gilded iron was used for the spade. This suggests that the tone of the connecting part of the guard and the spade was not different for reason of visual harmonization. Potential applied plating method can be amalgam, dippping in molten brass, and brushing but the analysis result suggests that dipping in molten brass method is the most likely accepted method. The brass guard of knife was joined by tin-lead solder. Rivet used to fix the blade was made by pure iron as an optimum material which satisfies flexibility and strength.

Analysis of Molecular Expression in Adipose Tissue-Derived Mesenchymal Stem Cells : Prospects for Use in the Treatment of Intervertebral Disc Degeneration

  • Jin, Eun-Sun;Min, Joongkee;Jeon, Sang Ryong;Choi, Kyoung Hyo;Jeong, Je Hoon
    • Journal of Korean Neurosurgical Society
    • /
    • v.53 no.4
    • /
    • pp.207-212
    • /
    • 2013
  • Objective : Recent studies have shown encouraging progress toward the use of autogenic and allogenic mesenchymal stem cells (MSCs) to arrest, or even lead to partial regeneration in, intervertebral disc (IVD) degeneration. However, this technology is still in its infancy, and further development is required. The aim of this study was to analyze whether rat adipose-derived mesenchymal stem cells (ADMSC) can differentiate towards IVD-like cells after treatment with transforming growth factor ${\beta}3$ (TGF-${\beta}3$) in vitro. We also performed quantitative analysis of gene expression for ADMSC only, ADMSCs treated with TGF-${\beta}3$, and co-cultured ADMSCs treated with TGF-${\beta}3$. Methods : ADMSCs were sub-cultured to homogeneity and used in fluorocytometry assays for CD11, CD45, and CD90/Thy1. ADMSCs were differentiated in spheroid culture towards the chondrogenic lineage by the presence of TGF-${\beta}3$, dexamethasone, and ascorbate. We also co-cultured pure ADMSCs and nucleus pulposus cells in 24-well plates, and performed immunohistochemical staining, western blotting, and RT-PCR for quantitative analysis of gene expression. Results : Results of fluorocytometry were positive for CD90/Thy1 and negative for CD11 and CD45. TGF-${\beta}3$-mediated induction of ADMSCs led to the expression of the differentiation markers of intervertebral disc-like cells, such as aggrecan, collagen II, and sox-9. Co-cultured ADMSCs treated with TGF-${\beta}3$ showed higher expression of differentiation markers and greater extracellular matrix production compared with ADMSCs treated with TGF-${\beta}3$ alone. Conclusion : ADMSC treated with TGF-${\beta}3$ may be an attractive source for regeneration therapy in degenerative IVD. These findings may also help elucidate the pathologic mechanism of MSC therapy in the degeneration of IVD in vivo.

Ore Geology of Skarn Ore Bodies in the Kasihan Area, East Java, Indonesia (인도네시아 까시한지역 스카른광체의 광상학적 특성)

  • Han, Jin-Kyun;Choi, Sang-Hoon
    • Economic and Environmental Geology
    • /
    • v.45 no.1
    • /
    • pp.1-8
    • /
    • 2012
  • Copper-zinc-bearing skarns of the Kasihan area developed at limestone layers in the sedimentary facies of the Late Oligocene Arjosari Formation. The skarns consist mainly of fine-grained, massive clinopyroxene-garnet, garnet, garnet-epidote, and epidote skarns. Most copper and zinc(-lead) ore mineralization occur in the clinopyroxene-garnet and garnetepidote skarn, respectively. Clinopyroxene occurs as a continuous solid solution of diopside and hedenbergite (from nearly pure diopside up to ${\approx}34$ mole percent hedenbergite), with a maximum 28.2 mole percent johannsenite component. The early and late pyroxenes of Kasihan skarns are diopsidic and salitic, respectively. They fall in the fields typical Cu- and Zn-dominated skarns, respectively. Garnet displays a relatively wide range of solid solution between grossular and andradite with up to ${\approx}2.0$ weight percent MnO. Garnet in early pyroxene-garnet skarn ranges from 49.1 to 91.5 mole percent grossular (mainly ${\geq}78$ mole % grossular). Garnets in late garnet and garnet-epidote skarns range from 2.8 to 91.4 mole percent grossular (mainly ${\geq}70$ mole % for garnet skarn). Epidote compositions indicate solid solutions of clinozoisite and pistacite varying from 65.8 to 76.2 mole percent clinozoisite. Phase equilibria indicate that skarn evolution was the result of interaction of water-rich fluids ($X_{CO_2}{\leq}0.1$) with original lithologies at ${\approx}0.5$ kb with declining temperature (early clinopyroxene-garnet and garnet skarn, ${\approx}450$ to $370^{\circ}C$; late garnet-epidote and epidote skarn, ${\approx}370$ to $300^{\circ}C$).

Preparation and Properties of Low Density Polyethylene/Organo-clay Nanocomposite (저밀도 폴리에틸렌 나노복합재료의 제조 및 특성)

  • Moon, Sung-Chul;Jung, Hyo-Sun;Lee, Jae-CHul;Hong, Jin-Who;Choi, Jae-Kon;Jo, Byung-Wook
    • Applied Chemistry for Engineering
    • /
    • v.16 no.1
    • /
    • pp.52-60
    • /
    • 2005
  • In this study, low density polyethylene/organo-clay nanocomposites were prepared by melt blending. Thermal property, structure, and morphology of the LDPE/organo-clay nanocomposites were investigated. When the composition ratios of the compounds of LDPE/PE-g-MA/organo-clay were 90/10/1~10 (w/w/w), X-ray diffractograms of LDPE/organo-clay nanocomposites revealed that the intercalation of polymer chains lead to increase the spacing between clay layers. TEM microphotographs showed that LDPE was intercalated into organo-clay. TGA performed under air atmosphere demonstrated a great increase in thermal stability of the LDPE/organo-clay nanocomposties. The maximum decomposition temperature of LDPE/organo-clay nanocomposite was increased about $80^{\circ}C$ compared with pure LDPE. When the organo-clay contents were 1.0~5.0 wt%, the LOI values were increased with increasing the organo-clay content, but in the case of the contents more than 5.0 wt%, the LOI values were not increased any more.

WBI Design and Implementation for active instruction in high school curriculum information society and computer (능동적인 학습을 위한 고교 정보사회와 컴퓨터 교과의 WBI 설계 및 구현이동)

  • Bae, Seok-Chan;Du, Chang-Won
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2007.06a
    • /
    • pp.895-901
    • /
    • 2007
  • Currently the advancement of the computer and the Internet sees the direction of studying freely to do, it does not receive not to be, the student the environment it will be able to study oneself it is doing the direct help of the teacher and to be possible. Plan and it embodied the high school information society which it follows in 7th curriculum and the WBI of computer subject from the dissertation which it sees. In order to improve the qualify of curriculum ultimately, it endeavored. Territory it analyzes a subject contents first, especially it surveys, foundation it hardens, the actual training semester and pure with studying of self-evaluation do to become accomplished, studying oneself to sleep the possibility of doing own lead studying which is the possibility of studying spontaneously and integrated textbook studying in same tine it does to be with they are composing of the education paradigm the flag for a problem solving ability and an originality accident. In this dissertation used the php, Apache web server and the DBMS used the MySQL. To program member joining, the information society and computer curriculum take a course and test, it questions and, it is composed to data mourge. After taking a course, simultaneously lecturing a paper and online instruction, set up a foundation and quering that gratify one's curiosity thus it will be able to digest a study in once.

  • PDF