• 한국정보통신학회논문지
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• 제22권1호
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• pp.26-32
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• 2018

단백질의 이차구조는 단백질의 진화, 구조, 기능을 연구하는데 중요한 정보이다. 단백질 서열 정보만을 이용하여 단백질의 이차 구조를 예측하는 분야에 심층 학습 방법들이 최근 들어 활발히 적용되고 있다. 이러한 방법에서 널리 사용되는 입력은 단백질 서열을 변환하여 만들어진 단백질 프로파일이다. 본 논문에서는 효과적인 단백질 프로파일을 얻기 위하여 단백질 서열 탐색 방법으로 PSI-BLAST와 더불어서 HHblits를 사용하였다. 단백질 프로파일의 구성에 사용되는 상동 단백질 서열을 결정하기 위한 유사도 문턱치와 상동 단백질 서열 정보를 반복적으로 사용하는 회수를 조절하였다. 합성곱 신경망과 순환 신경망을 사용하여 단백질 이차구조를 예측하였는데, 진화적 정보를 한번만 추가하여 만들어진 단백질 프로파일이 효과적이었다.

• 대한전기학회논문지:전기물성ㆍ응용부문C
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• 제54권8호
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• pp.365-370
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• 2005

Microwave diagnostics have been widely utilized to measure the important parameters of high temperature and high density plasmas. Reflectometry is known as a promising microwave diagnostic which has a number of merits to measure electron density profiles. In the KSTAR device, X-mode FM reflectometry is planned to measure the plasma density profiles. FM reflectometry is required to extract phase information on raw mixer IF signals, thereby obtaining time-of-flight of reflectometry signals. It is known that the data analysis method is crucial to determine the performance of FM reflectometry In fact, there are several analysis programs which have been utilized in various FM systems. Since each program was developed for a specific device, however, it is difficult to directly apply it to a different reactor like the KSTAR device. It is necessary, therefore, to develop a data analysis program for the KSTAR FM reflectometry. In this paper, complex digital demodulation (CDM) and wavelet transformation are examined in terms of the performance of density profile reconstruction. For the comparison of both methods, FM reflectometry signals are generated on the basis of assumed profiles and the interaction of the X-mode wave and the plasma. In order to see how well both methods work under various conditions, three types of profiles are assumed and noise effects are included. As a result, both methods work well under the condition of gentle density gradient and small noise level. As density gradient becomes steeper and noise level gets higher. the reconstruction performance of wavelet is better than that of CDM.

• 한국컴퓨터정보학회논문지
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• 제17권6호
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• pp.131-144
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• 2012

모델 기반 개발 방법은 모바일 어플리케이션 개발의 특성을 잘 수용할 수 있으므로 모바일 어플리케이션 개발에 적용하기 위한 다양한 연구가 진행 중이다. 그러나 모델 기반 개발 수행 시 PIM과 PSM 설계에 필요한 UML 프로파일의 체계적인 개발 관련 연구는 부족한 상황이며, 프로파일을 활용한 모델 변환 기법 관련 연구도 요구되고 있다. 이에 본 논문에서는 모바일 어플리케이션의 PIM과 PSM 설계에 적용할 UML 프로파일 구성 기법과 이를 활용한 모델 변환 기법을 제안한다. 제안한 기법은 모바일 어플리케이션의 특성을 반영하여 스테레오타입을 분류한 후 프로파일 구성 지침에 따라 각 모델에 적용할 프로파일을 구성한다. 프로파일을 적용하여 구성한 PIM은 모델 변환 절차에 따라 프로파일 간 대응 규칙에 의하여 초기 PSM으로 변환되며, 모바일 플랫폼의 세부정보를 반영하여 구성한 PSM 템플릿을 적용하여 정제한 PSM으로 변환 생성된다. 제안한 기법의 유용성을 확인하기 위하여 안드로이드 기반 위치 기록 어플리케이션을 대상으로 제안 기법을 적용하여 개발하고, 기존의 기법들과 비교를 수행하였다.

• 한국토양비료학회지
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• 제49권5호
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• pp.434-439
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• 2016

Anthropogenic soil in cropland is formed in the process of subsoil reversal and the refill of soil into cropland. However, there was little information on the chemical properties within soil profiles in anthropogenic soil under rice paddy near the river. In this study, we investigated the chemical properties within soil profiles in the anthropogenic soil located at 4 sites in Gumi, Kimhae, Chungju, and Euiseong to compare with the natural paddy soil near the river. Among particle sizes, the sand content decreased under soil profiles but the silt and clay contents increased compared to the natural paddy soil in soil profiles. Organic matter content in topsoil of anthropogenic soil was lower than in that of natural soil, which was shown the contrary tendency within soil profiles. Also, the soil pH, available $P_2O_5$, and exchangeable cations were higher in anthropogenic soil compared to natural paddy soil at topsoil, which was maintained these tendency into soil depth. Nutrients may be equally distributed in anthropogenic soil during the process of refill in paddy soil near the river. This results indicated that anthropogenic soil would contribute to carbon sequestration, the mitigation of compaction, and reduction of fertilizer application in paddy soil. Therefore, characteristics of anthropogenic soil can be used for the soil management in cropland.

• 한국임상수의학회지
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• 제24권2호
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• pp.160-163
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• 2007

Patients often present with spontaneous bleeding, or a bleeding disorder may be discovered when an otherwise healthy dog develops marked bleeding during or after surgery. In this study, we were aimed to elucidate whether the cesarean section in dogs has influence on the coagulation profiles. And we gained the normal data on a panel of screening laboratory tests which allow accurate characterization of a hemostatic defects in dogs. Of the 20 healthy adult dogs, buccal mucosa bleeding time (BMBT) was $83.0{\pm}10.5$ seconds, platelet count was $24.0{\pm}3.5{\times}10^4/{\mu}l$, activated partial thromboplastin time (APTT) was $8.8{\pm}2.0$ seconds, the concentration of fibrinogen was $288.5{\pm}77.9mg/dl$, and the concentration of fibrin degradation products (D-dimer) was <250.0 ng/ml. Coagulation profiles before and after cesarean section of 13 cesarean sectioned dogs were in the normal range and there were no statistical differences in coagulation profiles between normal dogs and cesarean sectioned dogs (p>0.05). The results suggested that labor and cesarean section in healthy dogs did not alter coagulation profiles.

• Nutrition Research and Practice
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• 제9권5호
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• pp.489-495
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• 2015

BACKGROUND/OBJECTIVES: The present study was conducted to investigate the effects of dried Momordica charantia aqueous extracts (MCA) and ethanol extracts (MCE) on obesity and lipid profiles in mice fed a high-fat diet. MATERIALS/METHODS: Forty two ICR mice were randomly divided into six groups. The normal group was fed a basal diet, and other groups were fed a 45% high-fat diet (HFD) for 7 weeks. The normal and HFD groups were also orally administered distilled water each day for 7 weeks. The remaining groups received Momordica charantia extract (0.5 or 1.0 g/kg/day MCA, and 0.5 or 1.0 g/kg/day MCE). In order to measure the anti-obesity and lipid profile improvement effects, body and visceral tissue weight, lipid profiles, plasma insulin levels, hepatic malondialdehyde (MDA) levels and superoxide dismutase (SOD) activity were measured. RESULTS: Both MCA and MCE significantly decreased body and visceral tissue weight relative to those of the HFD group (P < 0.05). Additionally high doses of MCE and MCA significantly reduced the plasmatic insulin levels compared to the HFD groups (P < 0.05) to concentrations comparable to those found in the normal group. MCA and MCE supplementation also significantly modulated the lipid profiles in plasma, liver, and feces compared to mice fed the HFD (P < 0.05). Furthermore MCA and MCE significantly increased hepatic SOD activity, and reduced MDA generation in the liver of the HFD mice (P < 0.05). CONCLUSIONS: Results from the present study suggest that Momordica charantia extracts have anti-obesity effects and the ability to modulate lipid prolife of mice fed a HFD by suppressing body weight gain, visceral tissue weight, plasma and hepatic lipid concentrations, and lipid peroxidation along with increasing lipid metabolism.

• Journal of the Korean Data Analysis Society
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• 제20권6호
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• pp.3049-3067
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• 2018

최근 조직몰입(organizational commitment) 3요인(정서적 몰입, 규범적 몰입, 지속적 몰입) 모델(Allen, Meyer, 1990, 1991) 관련 연구에서 사람중심 접근법(person-centered approach)이 많은 관심을 받고 있지만 아직 국내 연구자들에게는 크게 확산되지 못하고 있다. 이에 본 논문은 사람중심 접근법의 개념과 관련 자료분석 방법을 군집분석(cluster analysis)과 잠재프로파일분석(latent profile analysis)을 중심으로 소개하고자 한다. 또한 이러한 방법들의 실제 적용 사례를 제시하기 위해 국내 직장인들 349명으로부터 수집한 자료를 바탕으로 군집분석과 잠재프로파일분석을 각각 실행하여 각 분석으로부터 6개의 조직몰입 프로파일 유형들을 도출하였으며 그 결과를 비교하였다. 뿐만 아니라, 조직몰입 프로파일 유형 간 이직의도(turnover intention)의 차이를 살펴봄으로써 도출된 프로파일의 타당성을 확인하였다. 본 논문은 조직몰입에 대한 기존의 변수중심 접근법(variable-centered approach)에 대한 보완적 방법으로 사람중심 접근법이 갖는 의미를 이해하고, 나아가 국내 직장인들의 조직몰입 프로파일 유형을 살펴볼 수 있다는 점에서 국내 연구자들 뿐만 아니라 실무담당자들에게 시사하는 바가 크다고 할 수 있다.

• 한국지반공학회논문집
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• 제25권12호
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• pp.69-85
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• 2009

댐체의 내진설계를 위해서 각 부분의 정확한 동적 물성치 산정이 매우 중요하다. 그러나 기존 댐체의 내진 설계시 현장 시험결과 없이 가정 물성을 이용하거나 문헌연구를 이용하여 해석을 수행하여 신뢰성 있는 결과를 도출하지 못하였다. 따라서 현장 실험을 통하여 댐체의 전단파속도로 대표되는 동적물성치를 효율적으로 획득해야 한다. 이를 위하여 본 연구에서는 표면파 탐사 기법을 적용하여 락필댐 심벽부와 사력부의 전단파 속도를 도출하였다. 대표적인 표면파 기법인 SASW기법과 새롭게 개발된 HWAW 기법을 이용하여 6개 댐에서 수행하여 전단파 속도를 획득하였으며, 기존 연구결과를 종합하여 댐체의 깊이별 전단파 속도의 D/B와 구속압-전단파속도 관계식를 구축하였다. 획득한 D/B와 관계식은 기존에 사용되었던 Sawada와 Takahashi의 결과와 비교 분석하였다

• Safety and Health at Work
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• 제14권1호
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• pp.85-92
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• 2023

Background: Presenteeism is closely related to work performance, work quality and quantity, and productivity at work. According to the job demand-control-support model, job demand, job control, and support play important roles in presenteeism. The present study investigated job characteristics profiles based on the job demand-control-support model and identify the association between job characteristics profiles and presenteeism. Methods: This secondary data analysis used the Sixth Korean Working Condition Survey, a nationwide cross-sectional dataset. The study included 25,361 Korean wage workers employed in the workplace with two or more workers. Participants were classified into four job characteristics profiles based on the job demand-control-support model, using latent profile analysis, and logistic regression was performed to examine the association between study variables. Results: Overall, 11.0 % of study participants reported experience of presenteeism in the past 12 months. Age, sex, location, monthly income, shift work, work hours, health problems, and sleep disturbances were significantly associated with presenteeism. The rate of presenteeism was the highest in the passive isolate group. The passive collective, active collective, and low-stain collective groups had a 23.0%, 21.0%, and 29.0% lower likelihood of experiencing presenteeism, respectively, than the passive isolate group. Conclusions: The job demand-control-support profiles and the risk of presenteeism were significantly associated. The most significant group that lowered the experience of presenteeism was the low-strain collective group, which had a low level of demand and high levels of control and support. Therefore, we need a policy to reduce job demand and increase job control and support at the organizational and national levels.

• 한국간호교육학회지
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• 제30권2호
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• pp.160-169
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• 2024

Purpose: This study aimed to identify the career decision profiles for nursing students and analyze their career barriers, preparation behaviors, decision-making self efficacy, and adaptability according to the career decision profiles. Methods: This cross-sectional study used content analysis. A total of 219 nursing students enrolled in two private Korean universities participated in this study. The data were collected in person and via email between December 8 and 31, 2020. Results: The decidedness and comfort results were statistically significant. Four clusters were identified: undecided-uncomfortable, decided-uncomfortable, decided-comfortable, and undecided-comfortable. Most participants were found to be decided-uncomfortable, followed by decided-comfortable, undecided-uncomfortable, and undecided-comfortable. The self efficacy scores were higher for the decision-comfortable profile than for the undecided-uncomfortable and decided-uncomfortable profiles. The mean adaptability scores were higher for the decision-comfortable profile than for the undecided-comfortable profile. Career barriers were negatively correlated with preparation behavior, decision-making self efficacy, and adaptability, while preparative behaviors were positively correlated with decision-making self efficacy and adaptability. Decision-making self efficacy was positively correlated with adaptability. The mean career barriers, preparation behaviors, decision-making self efficacy, and adaptability scores differed significantly across profiles. The mean career barrier score was higher for the undecided-uncomfortable than for the decided-comfortable profile; preparation behaviors exhibited no significant differences. Conclusion: Tailored career coaching and counseling programs based on personal characteristics and areas of interest are needed for freshmen and senior nursing students to reduce career barriers and to improve preparation behaviors, decision-making self efficacy, and adaptability.