• Biomolecules & Therapeutics
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• 제6권3호
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• pp.296-302
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• 1998

The bioequivalence of two cyclosporin A products was evaluated in 26 normal male volunteers (age 25 ~33 yr, body weight 56~84 kg) following single oral administration. Test product was a hard capsule containing the granule of cyclosporin A (Chong Kun Dang Corp., Korea) and reference product, Sandimmun", was a soft capsule containing surfactant, oil, alcohol and cyclosporin A (Sandoz, Swiss). Both products contain 100 mg of cyclosporin A. Four capsules of the test and the reference product were administered to the volunteers, respectively, by randomized two period cross-over study (2$\times$2 Latin square method). Average drug concentrations at each sampling time and pharmacokinetic parameters were not significantly different between two products (p>0.05); the area under the concentration-time curve to last sampling time (24 hr) (AU $Co_{24}$) (5034.8$\pm$ 1760.6 vs 4635.4$\pm$ 1158.9 ng . h/ml), maximum plasma concentration ( $C_{max}$) (1002.7$\pm$353.1 vs 980. 4$\pm$ 171.7 ng/71), and mean residence time (MRT) (6.16$\pm$0.81 vs 5.64$\pm$0.50 h). The differences of mean AUC 7-,4,7~, T_ and MRT between the two products (7.93,2.22,16 and 8.39%, respectively) were less than 20% given as a guideline. The power (1-$\beta$) and treatment difference ($\Delta$) for AU $Co_{24}$, $C_{max}$ and MRT were more than 0.8 and less than 0.2, respectively. Although $T_{max}$ of the two products was significantly different each other (p<0.05), $T_{max}$ might be an insignificant parameter because cyclosporin A generally requires long-term administration. From these results, the two products are bioequivalent.alent.t.

• 한국의류학회지
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• 제38권5호
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• pp.627-637
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• 2014

This study explored the product attributes Vietnamese mothers consider for the purchase of children's wear, the differences of product attributes between groups with different levels of conspicuous consumption, and the extent to which the Korean wave affects the purchasing behavior of children's wear brands. The results are as follows. First, the product attribute that Vietnamese mothers consider most when purchasing children's clothes is the comfort in physical activities. Fabric type and quality, sizing and fit, durability, color, child suitability, design, cutting and construction, price, fashionability, and maintenance and laundering are the other attributes (respectively) that influence the purchase of children's wear. Second, the high conspicuous consumption group considers brand, maintenance and laundering, durability, the reactions of others, and fashionability significantly more than the low conspicuous consumption group. Third, the purchase intention of Korean children's wear brands is affected by the perception of the Korean wave than the influence of the reference group or the tendency of conspicuous consumption. The results show that low prices and practicality were important considerations for children's clothing purchases by Vietnamese mothers; however, brand name and fashionability were more powerful predictors for the high conspicuous consumption group. Those with a high perception of the Korean wave also had a higher intention of Korean children's wear brand, which is indicative of the halo effect of the Korean wave. Thus, Korean children's wear brands that plan to enter the Vietnamese market should make active use of the Korean wave.

• 대한임상검사과학회지
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• 제36권2호
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• pp.121-126
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• 2004

The primary goal of six sigma is to improve patient satisfaction, and thereby profitability, by reducing and eliminating defects. Defects may be related to any aspect of customer satisfaction: high product quality, schedule adherence, cost minimization, process capability indices, defects per unit, and yield. Many six sigma metrics can be mathematically related to the others. Literally, six means six standard deviations from the mean or median value. As applied to quality metrics, the term indicates that failures are at least six standard deviations from the mean or norm. This would mean about 3.4 failures per million opportunities for failure. The objective of six sigma quality is to reduce process output variation so that on a long term basis, which is the customer's aggregate experience with our process over time, this will result in no more than 3.4 defect Parts Per Million(PPM) opportunities (or 3.4 Defects Per Million Opportunities. For a process with only one specification limit (upper or lower), this results in six process standard deviations between the mean of the process and the customer's specification limit (hence, 6 Sigma). The results of applicative six sigma experiment studied on 18 items TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA tests in clinical chemistry were follows. Assessment of process performance fits within six sigma tolerance limits were TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA with 72.2%, items that fit within five sigma limits were total bilirubin, chloride and sodium were 3 sigma. We were sure that the goal of six sigma would reduce test variation in the process.

• 한국CDE학회논문집
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• 제17권6호
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• pp.417-425
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• 2012

In recent years, great attention has been paid to using simple physical objects as tangible objects to improve user interaction in augmented reality (AR) environments. In this paper, we address AR-based user interaction using tangible objects, which has been used as a key component for virtual design evaluation of engineered products including digital handheld products. We herein consider the use of two types (product-type and pointer-type) of tangible objects. The user creates input events by touching specified parts of the product-type object with the pointer-type object, and the virtual product reacts to the events by rendering its visual and auditory contents on the output devices. The product-type object is used to reflect the geometric shape of a product of interest and to determine its position and orientation in the AR environment. The pointer-type object is used to recognize the reference position of the pointer (or finger) in the same environment. The rapid prototype of the product is employed as a good alternative to the product-type object, but various alternatives to the pointer-type object can be considered according to fabrication process and touching mechanism. In this paper, we present four alternatives to the pointer-type object and investigate their strong and weak points by performing experimental comparison of their various aspects including interaction accuracy, task performance, and qualitative user experience.

• 복식문화연구
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• 제25권4호
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• pp.529-542
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• 2017

The purpose of this study is to utilize technology as basic data for smart clothing product research and development. This technology can recognize user's motion according to characteristics types and functions of wearable smart clothing products. In order to analyze the case of motion recognition products, we searched for previous research data and cases referred to as major keywords in leading search engines, Google and Naver. Among the searched cases, information on the characteristics and major functions of the 42 final products selected on the market are examined in detail. Motion recognition for smart clothing products is classified into four body types: head & face, body, arms & hands, and legs & feet. Smart clothing products was developed with various items, such as hats, glasses, bras, shirts, pants, bracelets, rings, socks, shoes, etc., It was divided into four functions health care type for prevention of injuries, health monitor, posture correction, sports type for heartbeat and exercise monitor, exercise coaching, posture correction, convenience for smart controller and security and entertainment type for pleasure. The function of the motion recognition smart clothing product discussed in this study will be a useful reference when designing a motion recognition smart clothing product that is blended with IT technology.

• The Journal of Asian Finance, Economics and Business
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• 제5권4호
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• pp.117-125
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• 2018

As various types of information technology systems are becoming more pervasive than ever, many studies have evaluated the systems from the user perspective. Some of them have used surveys to measure consumers' cognitive responses to the target technology. However, this method may cause problems if the survey participants do not have a useful frame of reference for evaluating an unfamiliar system. To examine this issue, the current study empirically tested the effect of personal product knowledge on the predictability of a behavioral model, such as Technology Acceptance Model. A series of measurement invariance tests as well as multi-group comparison tests were conducted for rigorous examination of the data. Our analysis showed that the variance of attitude that is explained by the two believes (perceived usefulness and ease of use) was relatively small when the survey respondents had lower amount of product knowledge. Moreover, the group had weaker causal relationship between attitude and intention to use the technology, hindering the predictability of the research model. The results indicated that respondents should have a certain amount of knowledge of the target system in order to form accurate beliefs and behavioral decisions. The findings of this study provide important implications on sampling strategies for researchers with new technology.

• Nuclear Engineering and Technology
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• 제36권1호
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• pp.36-46
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• 2004

The ISAAC fission product release calculation is based on detailed FPRAT models developed by Jaycor. For volatile fission product release calculations, either the Cubicciotti steam oxidation correlation or the NUREG-0772 correlation is used. In this study, evaluation is carried out for these volatile fission product release models. As a result, in the case of early release, the IDCOR model with an in-vessel Te release option shows the most conservative results and for the late release case, the NUREG-0772 model shows the most conservative results. Considering both early and late release, the IDCOR model with an in-vessel Te bound option is evaluated to show mitigated conservative results. In addition, a sensitivity study on detailed core nodalization is performed. In the study, 380 horizontal fuel channels in the Wolsong plant are nodalized into 12 (6 channels per loop, $3{\times}3$ Core Pass) representative channels and detailed by 16/20/24 channels. For reference accidents, LOAH and large LOCA are selected as representing high and low pressure sequences, respectively. According to the results, the original 12 channel approach with $3{\times}3$ core passes is evaluated to be sufficient as an optimal scheme.

• Industrial Engineering and Management Systems
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• 제13권2호
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• pp.203-209
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• 2014

This research designed and implemented a supply chain risk management platform and applied it to a case study of reduced-fat Lanna pork sausage as a new product development project. The proposed framework has three stages: risk identification, risk assessment, and risk mitigation. Seventeen risk agents with 17 risk events were identified based on SWOT analysis and the Porter Five Forces concept through the process of planning, sourcing, making and delivering, partially captured from the supply chain operations reference model in the first stage. In the second stage, an house of risk (HOR) framework was applied to present the impacts of each risk agent. In the third stage, eight risk agents with high impact were selected to design 21 preventive actions. Finally, three preventive actions with the highest effectiveness to difficulty ratio scores-'sales evaluation of familiar products', 'increasing distribution channels and promotions to improve sales', and 'work flow improvement for work safety'-were then recommended for this new product development.

• 한국엔터테인먼트산업학회논문지
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• 제13권5호
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• pp.111-117
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• 2019

분석하여 화장품 포장 디자인에 사용된 컬래버레이션 사례를 연구, 특히 쿠션화장품 중 캐릭터 이미지와 컬래버레이션 하여 화장품 디자인에 사용된 사례를 분석하였다. 화장품 디자인 컬래버레이션 연구를 통해 제품 가치와 브랜드 이미지를 제고시키고, 소비자에게 새롭고 개성 있는 제품을 제공하여 젊은층 소비자 그룹을 타겟팅, 유치하는 데 목적이 있다. 이 연구는 향후 화장품 포장 디자인을 하는데 참고할 만한 내용을 제공하리라 기대한다.

• 한국콘텐츠학회논문지
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• 제8권9호
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• pp.124-132
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• 2008

경제적 환경의 변화와 인터넷 등의 다양한 유통경로 등장으로 인해 경쟁이 심화되면서 가격은 아주 강력한 마케팅 수단이 되고 있다. 이에 따라 가격할인 등의 가격전략을 통해 소비자의 구매행동을 강화하는 현상을 볼 수 있는데, 많은 광고에서 가격할인 정보를 제시하면서 준거가격을 함께 제시하는 전략을 활발하게 사용하고 있다. 이에 따라 많은 연구들이 준거가격제시에 따른 광고효과를 검증하였는데, 본 연구에서는 기존의 제품에 한정된 준거가격 연구에서 확장하여 서비스 경우에 준거가격을 제시함에 따른 효과를 검증하고, 서비스의 명성에 따라 준거가격제시 방법에 따른 광고효과의 차이를 검증한다. 서비스의 명성과 준거가격제시 방법에 따른 실험을 설계하여 분석을 실시하였다. 분석결과, 서비스 광고에서 준거가격을 제시하는 경우에 가격태도 및 이용의도가 높은 것으로 나타났는데, 서비스 명성이 높은 경우에는 준거가격을 제시하는 것 보다 할인율을 표시하는 것이 더 효과가 높으며, 서비스 명성이 낮은 경우에는 준거가격 제시만으로 광고효과가 높아짐을 볼 수 있다. 이를 통해 서비스 경우에는 그 명성에 따라 준거가격을 제시하는 방법과 관련한 전략적 관점이 필요함을 알 수 있다.