• Journal of the Korean Wood Science and Technology
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• v.15 no.2
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• pp.1-15
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• 1987

This experiment was undertaken for the purpose of investigation of relative durability about thirty sorts of the korean native wood and nine sorts of the wood destroying fungi Polystictus versicolor, Irpex consors. Poria vaporaria, Merulius lacrymans, Schizophyllum commune, Trametes pini, Lenzites betulina, Paxillus panuoides by means of a laboratory methods. The results obtained are; (from the table 2 to 10) 1. By measuring the percentage of loss in weight with regard to Polystictus versicolor, the sap wood contained in Junipeus chinesis was calculated at 18.2%, therefore it is much higher durability than any others and the sap wood contained in Pinus densiflora was measured at 44.10%, therefore it is much lower durability than any others. 2. By measuring the percentage of loss in weight with regard to Irpex consors, the heart wood contained in Butula schmidtii was calculated at 1.23%, therefore durability is very high and the heart wood contained in Quercus dentata was calculated at 26.79%, therefore durability is very low. 3. By measuring the percentage of lass in weight with regard to Lenzites betulina, the heart wood contained in Betula schmidtii was calculated at 5.33%, therefore it is much higher durability than any others and the sap wood with regard to Abies holophylla was measured at 45.48%, therefore durability is very low. 4. By measuring the percentage of loss in weight with regard to Poria vaporaria, the sap wood contained in Fraxinus rhynchophylla was calculated at 5.57%, therefore durability is very high and the sap wood contained in Paulownia coreana was calculated at 35.6%, therefore it is much lower durability than any others. 5. By measuring the percentage of loss in weight with regard to Merulius lacrymans, the heart wood contained in Castanea crenata was measured at 0.09% and in the next place, the heart wood contained in Abies holophylla calculated at 0.15% did not decay almost and the sap wood contained in Cornus controversa was measured at 32.88%, therefore it is lower durability than any others. 6. By measuring the percentage of loss in weight with regard to Schizophyllum commune, the sap wood cantained in Junipensis chinensis was calculated at 1.09%, therefore durability is very high and the sap wood contained in Populus deltoides was calculated at 36.87%, it is much lower durability than any others. 7. By measuring the percentage of loss ill weight with regard to Trametes pini, the sap wood contained in Robinia pseudo-acacia was calculated at 1.33%, therefore durability is very high and the sap wood contained in Comus controversa was calculated at 33.19%, it is much lower durability than any others. 8. By measuring the percentage of loss ill weight with regard to Paxillus panuoides. the heart wood contained in Zelkova serrata was calculated at 1.73%, therefore durability is very high and the sap wood contained in Populus deltoides was calculated at 42.30%, therefore durability in very low. 9. By measuring the percentage of loss in weight with regard to Dardalea quercina, the heart wood contained in Castanea crenata was calculated at 0.92%, therefore durability is very high and the sap wood contained in Cornus controversa was calculated at 32.00% therefore durability is very low. The above results are summarized as follows 1. Durability between the heart wood and the soft wood find that it is nonsignificant, while durability is higher heart wood than sap wood. 2. Special sorts including in the element like Castanea cenata, Robinia pseudo-acacia, Juniperus chinensis and heart wood like Betula schmiditii and Styrax obasia are highly durable and soft wood like Cornus controversa, Populus davidiana, Salix koreensis, Celtis jessensis are lowly durable in general. 3. Among the wood destroying fungi Paxillus panuoides is highly durable and as follows. Poria vaporaria, Lenzites betulina and the Daedalea quercina is less in general and Irpex consors, Mersulius lacrymans are a middle degree.

• Journal of Life Science
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• v.24 no.10
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• pp.1063-1069
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• 2014

Reactive oxygen species (ROS) are known to lead to oxidation of lipids, proteins, and DNA and cause skin damage. Moreover, ROS promote melanogenesis, which causes melasma, age spots, and freckle. The main compounds of the herbal medicines Poria cocas, Glycyrrhiza uralensis, and Ulmus macrocarpa were reported to be parchymic acid, glabridin, and flavonoids, respectively. The aim of this study was to investigate the whitening and antioxidant effects of a mixture of P. cocas, G. uralensis, and U. macrocarpa extracts (PGUE) in B16F1 cells to develop whitening cosmetics. PGUE inhibited DPPH radicals and lipid peroxidation, in addition to high reduction power, compared with Glycyrrhiza uralensis ethylacetate extracts (GUEE). Furthermore, PGUE exhibited a protective effect against DNA oxidation induced by the hydroxyl radicals. In addition to its antioxidant activity, the inhibitory activity of PGUE against tyrosinase, which is associated with melanogenesis, was greater than that of arbutin used as a positive control. Moreover, PGUE exerted an inhibitory effect on melanin synthesis in live melanoma cells and reduced the expression levels of superoxide dismutase-1 (SOD-1) and tyrosinase related protein-1 (TRP-1). These results indicate that PGUE has skin whitening and antioxidant effects, suggesting that this mixture can be used as the main ingredient in the development of effective whitening cosmetics.

• Herbal Formula Science
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• v.25 no.2
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• pp.325-336
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• 2017

Objectives : The purpose of this study is to find out herb-pair prototype composed of Aconiti Radix(烏頭) or Aconiti Lateralis Preparata Radix(附子) written in ancient chinese medical classics. Methods : To search usages of Aconiti Radix and/or Aconiti Lateralis Preparata Radix, we have investigated the classics of herb and prescription such as "Fifty-two kinds of Diseases"("五十二病方"),"WuWeiHanDaiYiJian" ("武威漢代醫簡"),"Treatise on Febrile Caused by Cold"("傷寒論"),"Synopsis of Prescriptions of The Golden Chamber"("金匱要略"). Results : There were three herb pairs of Aconiti Radix and/or Aconiti Lateralis Preparata Radix in "Fifty-two kinds of Diseases", four herb pairs of it in "WuWeiHanDaiYiJian", eight herb pairs of it in "Treatise on Febrile Caused by Cold", and five herb pairs of it in "Synopsis of Prescriptions of The Golden Chamber". Conclusions : 1. Aconiti Radix herb-pairs written in ancient chinese medical classics are as follows ; Cinnamomi Cortex(桂), Arsenopyritum(礜) and Veratri Nigri Rhizoma et Radix(藜蘆). Zanthoxyli Fructus(蜀椒), Aconiti Lateralis Preparata Radix(附子), honey(蜜) and Asari Radix(細辛). 2. Aconiti Lateralis Preparata Radix(附子) herb-pairs written in ancient chinese medical classics are as follows ; Zanthoxyli Fructus(蜀椒), Paeonia Radx(芍藥), Ephedrae Herba(麻黃), Zingiberis Rhizoma(乾薑), Zingiberis Rhizoma(乾薑)-Allii Radix(葱白), Cinnamomi Cortex(桂), Atractylodis Rhizoma White(白朮), Poria(茯苓), Atractylodis Rhizoma White(白朮)-Poria(茯苓) and Gentianae Macrophyllae Radix(秦艽), Coisis semen(薏苡仁), Pinelliae Rhizoma(半夏). 3. In "Fifty-two kinds of Diseases"only Aconiti Radix was used and in "Treatise on Febrile Caused by Cold"only Aconiti Lateralis Preparata Radix was used, but in "WuWeiHanDaiYiJian"and "Synopsis of Prescriptions of The Golden Chamber"both herbs were used. 4. Method for reducing toxicity of Aconiti Radix and Aconiti Lateralis Preparata Radix was found in "Treatise on Febrile Caused by Cold"and "Synopsis of Prescriptions of The Golden Chamber".

• Journal of Oriental Neuropsychiatry
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• v.29 no.3
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• pp.145-163
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• 2018

Objectives: The study was designed to provide clinical evidence of homogeneity in analysis of the herbal medicine, Guipi decoction in treating insomnia, using a t-test of randomized controlled trials (RCTs). Methods: This study included RCTs that verified homogeneity of Guipi decoction in treating insomnia. Literature studies of CNKI (Chinese National Knowledge Infrastructure Database) were performed. The basic components group was made to the Guipi decoction of the Yixuerumen?s text. The excluded group was created with the number of herbs excluded from the basic components group. T-test performed that the effective rate in the basic components group and excluded groups. Results: The basic components of Guipi decoction contain Atractylodis Rhizoma Alba, Poria Sclerotium (Poria Sclerotium Cum Pini Radix), Polygalae Radix, Astragali Radix, Zizyphi Semen, Angelicae Gigantis Radix, Aucklandiae Radix, Glycyrrhiza uralensis Fischer, Ginseng Radix (Codonopsis Pilosulae Radix), Longanae Arillus. Herbs excluded from the basic components group were Longanae Arillus, Ginseng Radix (Codonopsis Pilosulae Radix), Glycyrrhiza uralensis Fischer and herbs added to the basic components group were Polygonum multiflorum Thunberg, Schisandrae Fructus, Salviae Militiorrhizae Radix, Paeoniae Radix Alba (in order from the most used to the least). T-test revealed the effective rate in the basic components group was not statistically significant compared to the excluded groups (p=0.161/p=0.162/p=0.103). Conclusions: Effectiveness in treatment of basic components of Guipi decoction and excluded groups were revealed to be homogeneous in treating insomnia. As the number of herbs in the basic components group decreased, mean value in effectiveness of treatment also decreased consequentially. However, there were no statistical significances.

• Herbal Formula Science
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• v.12 no.1
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• pp.79-92
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• 2004

This thesis aims to provide an analytical basis for existing or new prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines. To this end, prescriptions presented in the Various Changes in the Dominations of the Six Energies and their Relations with the Diseases of Plain Questions were analyzed based on the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine. This thesis focused on symptoms and prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines, which were described in tire Various Changes in tire Dominations of tire Six Energies and their Relations with the Diseases of Plain Questions with regard to the year when Taeeum is affecting the earth energy and the dampness energy is partially over-abundant. Those symptoms and prescriptions originate from the theory of the five elements and six climates. The symptoms were analyzed from the perspective of physiology. The prescriptions were first analyzed based on the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine. Then, a mix formula of oriental medicines pursuant to those prescriptions was studied. Lastly, established prescriptions, which were in conformity with the above prescriptions, were selected. From the physiological point of view, symptoms with regard to the year when Taeeum is affecting the earth energy and the dampness energy is partially over-abundant can be, based on the theory of the five elements and six climates, diagnosed as the symptoms from impaired kidney due to excessive dampness energy. Established prescriptions pursuant to prescriptions based on the theory for properties and tastes of Korean oriental herbal medicines can be broken down into the following: Poria powder with five herbs (Oryeongsan); Divine black bird decoction (Jinmootang); Tetrandra and astragalus decoction (Banggihoanggitang); Licorice, dried ginger, poria and bighead atractylodes decoction (Gamgangryeongchooltang); Spleen-reinforcing powder (Shilbeesan). Therefore, symptoms of six kinds of weather presented in the Various Changes in the Dominations of tire Six Energies and their Relations with tire Diseases of Plain Questions can be analyzed from the physiological point of view. As a result, in addition to the methodology that analyzes existing prescriptions within the boundary of the theory for properties and tastes of Korean oriental herbal medicines in Yellow Emperor's Canon of Internal Medicine, it is expected that a theoretical basis for new prescriptions can be provided by analyzing established prescriptions based on prescriptions from the theory for properties and tastes of Korean oriental herbal medicines.

• The Korea Journal of Herbology
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• v.27 no.5
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• pp.99-107
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• 2012

Objectives : This study was conducted to investigate the anti-obesity effects of mixed water extract of Plantaginis Semen & Poria (CJB) on obese rats induced with high fat diet. Method: Male Sprague-Dawley rats were divided into three groups; Normal group, high-fat (HF) group, HF+CJB(100 mg/kg, P.O.) for 8 weeks. The body weight, food intake and weights of adipose tissues were measured, respectively. Lipid profiles in serum were analyzed by automatic analyzer of blood. Obese marker proteins and the changes of NPY and LR immunoreactivities in hypothalamus were analyzed by Western blot and immunohistochemistry. Results : CJB significantly reduced body weight, food intake, adipose tissue weights compared to HF group. Serum triglyceride and total cholesterol were significantly higher in HF group than in Normal group however, CJB significantly lowered those of HF group. HDL-cholesterol level in CJB groups was elevated compared to HF group. The pAMPK in hypothalamus were decreased in that of HF group and that of CJB group decreased. Inversely, ACC was increased in HF group and that of CJB groups decrease. Expression of $PPAR{\gamma}$ in hypothalamus was increased by CJB treatment. However, $PPAR{\alpha}$ levels in CJB group were decreased compared to HF group. The expressions of NPY and LR in PVN and ARC of hypothalamus were decreased in CJB group, respectively. Conclusion : Administration of CJB can play anti-obesity through regulations of NPY and LR activities and obesity marker proteins in obese rat's hypothalamus.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.45 no.1
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• pp.77-85
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• 2019

OMiYakSung theory consists of various herbs that contain at least one or more of the five flavors. This theory has been used to prevent human diseases and enhance the immune system. The main objective of the present study was to investigate efficacy differences and changes in ingredients of blended and single herb extracts based on OMiYakSung theory. We selected three herbs Coptis japonica Makino, Cimicifuga heracleifolia Komarov, and white Poria cocos and assessed their physiological effect. As results, the blended extracts showed excellent cell migration effect at 400 ug/mL concentration, compared to the single extract. In addition, the blended extracts enhanced immune function by increasing the activity of dendritic cells and showed the highest antioxidant activity by DPPH assay and HPLC-ABTS assay. In this study, we developed a new materials that can be applicable to cosmetics and pharmaceuticals field by applying oriental medicine theory.

• Journal of Sasang Constitutional Medicine
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• v.34 no.4
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• pp.1-12
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• 2022

Objectives This paper investigates the origins, changes, and the constructive principles of Hyungbangjihwang-tang(荊防地黃湯). Methods Hyungbangjihwang-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Gogeumuigam(古今醫鑑)』, 『Sanghannon(傷寒論)』, 『Uihagjeongjeon(醫學正傳)』, 『Donguisusebowon·Sasangchobongwon(東醫壽世保元·四象草本卷)』, 『Donguisusebowon·Gabobon(東醫壽世保元·甲午本)』, 『Donguisusebowon·Sinchukbon(東醫壽世保元·辛丑本)』. Results and Conclusions The origins of Hyungbangjihwang-tang can be seen in three sections depending on the classification of medicinal herbs. Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風), Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), and Plantago asiatica L.(車前子) originated from Hyungbangpaedok-san(荊防敗毒散) included in 『Gogeumuigam』. Poria cocos Wolf.(茯苓) and Alisma canaliculatum(澤瀉) originated from Ohryoung-san(五苓散) included in 『Sanghannon』. Rehmannia glutinosa for hueichingensis(熟地黃) and Cornus officinalis S. et Z.(⼭茱萸) originated from Yukmijihwang-tang(六味地黃湯) included in 『Uihagjeongjeon』. Hyungbangpaedok-san was transformed into "Paedok-san" in 『Chobongwon(草本卷)』, Hyungbangpaedok-san in the 『Gabobon(甲午本)』 and 『Sinchukbon(辛丑本)』. Yukmijihwang-tang was mentioned as a Soyangin medicine in the 『Chobongwon』 and was later transformed into a Suhwagije-tang(水火旣濟湯) in 『Gabobon』. The meaning of Yukmijihwang-tang inherited in 『Sinchukbon』 as Dokhwaljihwang-tang and Hyungbangjihwang-tang. The medicinal herbs in Hyungbangjihwang-tang can be categorized in three sections by their functions, Schizonepeta tenuifolia Briq., Saposhnikovia divaricata Schischk., Notopterygium incisum Ting, Aralia cordata Thunb., and Plantago asiatica L. scatter the Pyohan(表寒) and make the Pyoeum(表陰) drop. Poria cocos Wolf.(茯苓) and Alisma canaliculatum(澤瀉) make the Pyoeum(表陰) drop through Lee-su(利水). Rehmannia glutinosa for hueichingensis(熟地黃) and Cornus officinalis S. et Z.(⼭茱萸) tonify Shin-won(腎元). The each principles of medicinal herbs corresponds to the stage of the "Cold-related Diarrhea in Soyangin Spleen Cold-based Exterior Cold disease(少陽人 脾受寒表寒病 亡陰病 身寒腹痛亡陰證)".

• Journal of Society of Preventive Korean Medicine
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• v.19 no.1
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• pp.131-144
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• 2015

Objective : This study was conducted to investigate anti-obesity effects of mixed-Powder(Raphani Semen, Coicis Semen, Poria, Plantaginis Testa & Theae folium)(HP) & mixed water extract(Citri Pericarpium, Crataegi Fructus, Maydis Stigma, Allium Skin) (HE) in mice fed a high-fat diet. Method : 50 Female ICR mice were divided into six groups; Normal group (Ve), high-fat diet group (Po), Po+HP(0.6g/kg) group(HP), Po+HE(1g/kg) group(HE), Po+(HP+HE) group(HPE), Po+(HP+HE)*2 group(DHPE). For 8 weeks, these groups were fed their respective diets. Body weight, liver weight and weights of adipose tissues, GOT/GPT index changes & Blood Glucose index changes were measured respectively. Lipid profiles in serum were analyzed by kit of blood. Results : Groups HP, HE, HPE, DHPE had significantly reduced body weight, liver weight, adipose tissue weights and GOT/GPT index, blood glucose index compared to the Po group. Also, serum triglyceride and total cholesterol, low density lipoprotein, were significantly reduced when compared to the Po group. Group G1 had significantly increased high density lipoprotein levels. Conclusion : Mixed powder (HP) & mixed water extract (HE) show anti-obesity effects in mice fed a high-fat diet.

• Journal of Evidence-Based Herbal Medicine
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• v.2 no.1
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• pp.19-24
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• 2009

GD68 is newly developed herb complex prescription. The constituent herbs of GD68 were Massa Medicata Fermentata, Atractylodis Rhizoma Alba, Poria, Zingiberis Siccatum Rhizoma, Crataegi Fructus, Saccarum Granorum, Agastachis Herba, Taraxaci Herba, Perillae Herba, Scutellariae Radix, Astragali Radix, Ginseng Radix, Houttuyniae Herba and Halloysitum Rubrum. The aim of this study was to examine feed value of GD68 in duck. The weight gain of ducks fed with supplemental GD68 high compared to those of the control. The feed intake and mortality of ducks fed with supplemental GD68 low compared to those of the control. The moisture, crude lipid and calorie content of the ducks fed GD68 were decreased, but the crude protein content of the ducks fed GD68 was increased. And we investigated the effect of GD68 on the production of cytokines in human T-cell line, MOLT-4 cells. GD68 plus concanavalin A (Con A) increased the interferon-$\gamma$ and interleukin-2 production compared with Con A alone. These results indicate that the supplemental GD68 may improve the production, meat quality and immunity of ducks.