• International Journal of Advanced Culture Technology
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• 제9권1호
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• pp.1-6
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• 2021

This study aims to test the relationship between the change in population size and population composition and crime changes. The analytical model includes variables representing changes in population size and population composition, three dependent variables for crime changes, and three control variables. Changes in popuvpdllation size and population composition are measured by indicators such as population size, gender, age groups, and immigrants and foreign workers, and crime changes by felonious, burglary, and violent crime volumes. The sample includes 154 cities and counties in South Korea, and the sample period is from 2010 to 2017. As a result of the analysis, I examine that the decrease in the number of young and men are likely to lead to a decline in felonious and violent crimes, but a high rate of the elderly and the increasing racial heterogeneity are likely to accelerate the fear and worries about crimes.

• Journal of Ecology and Environment
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• 제32권2호
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• pp.67-73
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• 2009

Soil $CO_2$ efflux can vary markedly in magnitude over both time and space, and understanding this variation is crucial for the correct measurement of $CO_2$ efflux in ecological studies. Although considerable research has quantified temporal variability in this flux, comparatively little effort has focused on its spatial variability. To account for spatial heterogeneity, we must be able to determine the number of sampling points required to adequately estimate soil $CO_2$ efflux in a target ecosystem. In this paper, we report the results of a study of the number of sampling points required for estimating soil $CO_2$ efflux using a closed-dynamic chamber in young and old Japanese cedar plantations in central Japan. The spatial heterogeneity in soil $CO_2$ efflux was significantly higher in the mature plantation than in the young stand. In the young plantation, 95% of samples of 9 randomly-chosen flux measurements from a population of 16 measurements made using 72-$cm^2$ chambers produced flux estimates within 20% of the full-population mean. In the mature plantation, 20 sampling points are required to achieve means within $\pm$ 20% of the full-population mean (15 measurements) for 95% of the sample dates. Variation in soil temperature and moisture could not explain the observed spatial variation in soil $CO_2$ efflux, even though both parameters are a good predictor of temporal variation in $CO_2$ efflux. Our results and those of previous studies suggest that, on average, approximately 46 sampling points are required to estimate the mean and variance of soil $CO_2$ flux in temperate and boreal forests to a precision of $\pm$ 10% at the 95% confidence level, and 12 points are required to achieve a precision of $\pm$ 20%.

• BMB Reports
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• 제38권2호
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• pp.182-190
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• 2005

Genetic heterogeneity of the tropical abalone, Haliotis asinina was examined using randomly amplified polymorphic DNA (RAPD) and microsatellite analyses. One hundred and thirteen polymorphic RAPD fragments were generated. The percentage of polymorphic bands of H. asinina across overall primers was 85.20%. The average genetic distance of natural samples within the Gulf of Thailand (HACAME and HASAME) was 0.0219. Larger distance was observed when those samples were compare with HATRAW from the Andaman Sea (0.2309 and 0.2314). Geographic heterogeneity and $F_{ST}$ analyses revealed population differentiation between H. asinina from the Gulf of Thailand and the Andaman Sea (p < 0.0001). Three microsatellite loci (CUHas1, CUHas4 and CUHas5) indicated relatively high genetic diversity in H. asinina (total number of alleles = 26, 5, 23 and observed heterozygosity = 0.84, 0.42 and 0.33, respectively). Significant population differentiation was also found between samples from different coastal regions (p < 0.0001). Therefore, the gene pool of natural H. asinina in coastal Thai waters can be genetically divided to 2 different populations; the Gulf of Thailand (A) and the Andaman Sea (B).

• Annals of Laboratory Medicine
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• 제38권6호
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• pp.545-554
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• 2018

Background: The increasing morbidity and mortality rates associated with Acinetobacter baumannii are due to the emergence of drug resistance and the limited treatment options. We compared characteristics of colistin-resistant Acinetobacter baumannii (CR-AB) clinical isolates recovered from patients with and without prior colistin treatment. We assessed whether prior colistin treatment affects the resistance mechanism of CR-AB isolates, mortality rates, and clinical characteristics. Additionally, a proper method for identifying CR-AB was determined. Methods: We collected 36 non-duplicate CR-AB clinical isolates resistant to colistin. Antimicrobial susceptibility testing, Sanger sequencing analysis, molecular typing, lipid A structure analysis, and in vitro synergy testing were performed. Eleven colistin-susceptible AB isolates were used as controls. Results: Despite no differences in clinical characteristics between patients with and without prior colistin treatment, resistance-causing genetic mutations were more frequent in isolates from colistin-treated patients. Distinct mutations were overlooked via the Sanger sequencing method, perhaps because of a masking effect by the colistin-susceptible AB subpopulation of CR-AB isolates lacking genetic mutations. However, modified lipid A analysis revealed colistin resistance peaks, despite the population heterogeneity, and peak levels were significantly different between the groups. Conclusions: Although prior colistin use did not induce clinical or susceptibility differences, we demonstrated that identification of CR-AB by sequencing is insufficient. We propose that population heterogeneity has a masking effect, especially in colistin non-treated patients; therefore, accurate testing methods reflecting physiological alterations of the bacteria, such as phosphoethanolamine-modified lipid A identification by matrix-assisted laser desorption ionization-time of flight, should be employed.

• ALGAE
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• 제37권1호
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• pp.63-74
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• 2022

Perennial stipitate kelps are globally distributed and individual species can inhabit broad latitudinal ranges, expressing notably longevous persistence. Despite the foundational role kelps provide to their communities, little is known about the variability in persistence of the stipitate kelps at local spatial scales. We studied the population persistence of Eisenia arborea, a heat- and wave force-tolerant perennial stipitate kelp with a distributional range extending from British Columbia to south of the range limit of all other northeast Pacific kelps, in Baja California Sur, Mexico. Persistence characteristics for E. arborea among sites were compared and used to test the hypothesis that stand persistence varied at local spatial scales around Isla Natividad, a Pacific island off the Baja California peninsula with documented spatiotemporal environmental heterogeneity. Collected individuals around the island were "aged" using the previously validated age estimation technique of counting annual cortical dark rings. After detecting no significant differences among sites in the covariation between estimated ages for collected individuals and stipe length, we utilized in-situ population-level stipe length measurements to more rapidly predict age structures within six stands around the island. Predicted age structures, and associated stand densities, revealed persistence characteristics and density varied at local scales and a strong positive relationship existed between stand density and stand mean and maximum ages. We speculate that stands responded differently to deterministic influences (e.g., the 2014-2016 marine heatwave and / or competition with Macrocystis) resulting in heterogenous local persistence of this foundation species.

• 응용통계연구
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• 제32권3호
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• pp.331-348
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• 2019

전이성 종양의 성장패턴 차이와 변화율에 따른 종양 이질성(tumor heterogeneity)을 파악하는 것은 종양세포의 약물에 대한 민감성을 파악하고 적절한 치료법을 찾아내기 위해 중요하다. 일반적으로 N개의 표본의 집단이 구분된다면 t-test 혹은 ANOVA 분석을 통해 집단별 평균의 차이에 대한 검정이 가능하다. 그러나 본 논문에서 다루는 데이터와 같이 집단이 구분되지 않는 경우 이러한 방법들은 사용될 수 없다. 표본들 사이의 이질성을 검정하기 위한 통계적 방법들이 연구되어 왔다. 최소 조합 t-검정 방법은 그 중 하나이다. 본 논문에서는 상이한 비율로 데이터를 양분하는 조합도 고려하는 최대 조합 t-검정 방법을 제안한다. 한편, 표본의 이질성을 검정하는 것이 군집분석에서 최적의 군집의 개수가 2개 이상인지를 검정하는 것과 같음에 착안하여 새로운 방법을 제안한다. 최대 조합 t-검정과 gap통계량을 이용하면 이전에 제안된 방법보다 개선된 제1종의 오류를 범할 확률과 검정력을 갖는다는 것을 모의실험을 통해 확인하였고 실제 자료 분석을 통해 결과를 도출하였다.

• 한국지역지리학회지
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• 제22권1호
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• pp.251-266
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• 2016

데시메트릭 매핑은 행정구역 단위로 집계된 인구자료를 행정구역 내부의 공간적 변이에 따라 재집계하여 고해상도의 인구분포 자료를 작성하는 가장 보편적인 기법이다. 본 연구에서는 데시메트릭 매핑을 이용한 인구분포 추정의 장단점을 검토하고, 그 개선방안으로서 지리가중회귀모형을 이용한 다변량 데시메트릭 매핑 기법을 제안하였다. 기존의 지표피복 데이터와 인구센서스 자료를 기반으로 지리가중회귀모형을 적용하여 각 집계단위별로 지표피복 유형과 인구밀도의 상관관계를 분석하고, 모형에서 산출된 회귀계수를 이용해 하위 공간구획의 인구 총수를 산정하였다. 그 결과 지리가중회귀모형 기반 다변량 데시메트릭 매핑 기법을 이용했을 때, 면적가중 보간법, 이진 데시메트릭 매핑, 피크노필렉틱 보간법, 최소자승회귀모형 기반 데시메트릭 매핑 기법 등 다른 지능형 보간법에 비해 정확한 인구분포 추정이 가능하다는 것을 확인하였다. 이는 지리가중회귀모형을 통해서 인구센서스 집계 단위별로 상이한 구역 내 공간적 이질성이 인구분포 추정에 적절히 반영되었기 때문인 것으로 평가할 수 있다.

• 보건교육건강증진학회지
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• 제30권2호
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• pp.41-53
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• 2013

Objectives: As the size of elderly population living alone grows, socioeconomic diversity has also increased. This study examined if social risk factors of poor self-rated health were distinguishable between the low income elderly and their non-low income counterparts both living alone. Methods: The '2006 Elderly Health Interview Survey' conducted by D-gu in Seoul was utilized. We divided the elderly living alone into two groups depending on their economic status: low income and non-low income. Employing logistic regression, we analyzed the associations of poor self-rated health with socio-demographic factors, health-related factors, social support, the relations with children, social activities, welfare service use, and the perception of neighborhood safety. Results: Proportion of rating one's own health being poor was different between two populations. Social support was important for the self-rated health of the non-low income elderly, while welfare service use, the perception of neighborhood safety, and the relations with children were noticeable for the low income elderly. Conclusions: To better understand the health need of elderly population living alone, their heterogeneity in socioeconomic characteristics should be taken into account.

• Asian-Australasian Journal of Animal Sciences
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• 제21권12호
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• pp.1710-1720
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• 2008

A comprehensive genome profiling study was undertaken based on automated genotyping and analysis of 20 microsatellite markers that involved 155 birds representing eight different populations. The distribution of microsatellite markers in each of these breeds helped us to decipher genetic heterogeneity, population genetic structure and evolutionary relationships of the present day chicken populations in India. All the microsatellite loci utilized for the analysis were polymorphic and reasonably informative. A total of 285 alleles were documented at 20 loci with a mean of 14.25 alleles/locus. A total of 103 alleles were found to be population/strain specific of which, only 30 per cent had a frequency of more than 10. The mean PIC values ranged from 0.39 for the locus ADL158 to 0.71 for loci MCW005 or ADL267 across the genomes and 0.55 in Dahlem Red to 0.71 in Desi (non-descript), among the populations. The overall mean expected and observed heterozygosity estimates for our populations were 0.68 and 0.64, respectively. The overall mean inbreeding coefficients (FIS) varied between -0.05 (Babcock) and 0.16 (Rhode Island Red). The pairwise FST estimates ranged from 0.06 between Aseel and Desi (non-descript) to 0.14 between Dahlem Red and Babcock. The Nei's genetic distance varied from 0.30 (WLH-IWD and WLH-IWF) to 0.80 (Dahlem Red and Babcock. Phylogenetic analysis grouped all the populations into two main clusters, representing i) the pure breeds, Dahlem Red and Rhode Island Red, and ii) the remaining six populations/strains. All the chicken populations studied were in the state of mild to moderate inbreeding except for commercial birds. A planned breeding is advised for purebreds to revive their genetic potential. High genetic diversity exists in Desi (non-descript), local birds, which can be exploited to genetically improve the birds suitable for backyard poultry.

• Journal of applied mathematics & informatics
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• 제9권2호
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• pp.459-517
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• 2002

The purpose of this paper is to provide a careful and accessible exposition of diffusive logistic equations with indefinite weights which model population dynamics in environments with strong spatial heterogeneity. We prove that the most favorable situations will occur if there is a relatively large favorable region (with good resources and without crowding effects) located some distance away from the boundary of the environment. Moreover we prove that a population will grow exponentially until limited by lack of available resources if the diffusion rate is below some critical value; this idea is generally credited to Thomas Malthus. On the other hand, if the diffusion rate is above this critical value, then the model obeys the logistic equation introduced by P. F. Verhulst .