• Journal of Powder Materials
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• v.6 no.1
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• pp.88-95
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• 1999

The purpose of this study is to investigate the manufacturing feasibility of WC-Co milling inserts via Powder Injection Molding (PIM) process. WC-Co is used in a wide variety of cutting tools due to its high hardness, stiffness, compressive strength and wear resistance properties. WC-Co parts for a high stress application were conventionally produced by the press and sinter method, which were Iimited to 2 dimensional shapes. Manufacturing WC-Co parts for a high stress application by PIM implies that tool efficiency can be highly improved due to increased freedom is design. P30 grade WC powder (WC-Co-TiC-TaC system) was mixed with RIST-5B133 binder and injection molded into milling inserts (Taegu Tech. Model WCMX 06T 308). The mean grain size of the powder was about 0.8$\mu$m. Injection molded specimens were debound by solvent extraction and thermal degradation method at various conditions. The specimens were sintered at 140$0^{\circ}C$ for 1 hr in vacuum. Carbon content, weight loss, dimensional change, and macro defects of the specimen were carefully monitored at each stage of the PIM process. PIMed WC-Co milling inserts reached 100% full density after sinteing. Its mechanical properties and micro-structures were comparable with the press and sintered milling insert. Carbon content of the sintered WC-Co insert was mainly determained by the atmosphere of thermal debinding. By controlling powder loading and injection molding condition, dimensional accuracy could be obtained within 0.4%. We confirm that PIM can not only be an alternative manufacturing method for WC-Co parts economically but also provide a design freedom for more effieient cutting tools.

• Korean Journal of Metals and Materials
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• v.49 no.1
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• pp.32-39
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• 2011

The present investigation was performed on the die compaction and sintering behavior of Fe micro-nano mixed powder with a mixed binder for powder injection molding. Warm die compaction of the feedstock for simulation of the static injection molding process was conducted using a cylindrical mold of 10 mm diameter at $100^{\circ}C$ under 4MPa. The die compaction of the micro-nanopowder feedstock underwent a uniform molding behavior showing a homogeneous distribution of nanopowders among the micropowders without porosity and distortion. After debinding, the powder compact maintained a uniform structure without crack and distortion, leading to a high green density of 64.2% corresponding to the initial powder loading of 65%. The sintering experiment showed that the micro-nanopowder compact underwent a near full and isotropic densification process during sintering. It was observed that the nanopowders effectively suppressed the growth of micropowder grains during densification process. Conclusively, the use of nanopowder for PIM feedstock might provide a new concept for processing a full density PIM parts with fine microstructure.

• Journal of Powder Materials
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• v.9 no.4
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• pp.203-210
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• 2002

A new PIM in-process joining technique has been developed for more complicated and functional PIM components by application of the exuded wax from the green compacts during solvent debinding step. At first, various stainless steels and iron compacts with rectangular shape were combined, and the joining behaviors and properties were investigated by shear and tensile test, and microscopic observation. Subsequently, perfect joined three pieces of thin and hollow compacts were obtained for the combination of same and different stainless steels, and it was difficult to join the iron and stainless steel compacts in hydrogen atmosphere because of the different starting temperature of shrinkage. However, pretty good joined iron and stainless steel compacts were obtained by consideration of particle size and vacuum atmosphere. Finally, for the combination of ferro-silicon and austenitic stainless steel compacts, high functionality (magnetic (1.60Tes1a) & non-magnetic) and perfect joint were obtained.

• Journal of IKEEE
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• v.20 no.1
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• pp.9-15
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• 2016

The endpoint detection (EPD) is the most important technique in plasma etching process. In plasma etching process, the Optical Emission Spectroscopy (OES) is usually used to analyze plasma reaction. And Plasma Impedance Monitoring (PIM) system is used to measure the voltage, current, power, and load impedance of the supplied RF power during plasma process. In this paper, a new decision making algorithm is proposed to improve the performance of EPD in SiOx single layer plasma etching. To enhance the accuracy of the endpoint detection, both OES data and PIM data are utilized and a newly proposed decision making algorithm is applied. The proposed method successfully detected endpoint of silicon oxide plasma etching.

• Korean Journal of Soil Science and Fertilizer
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• v.43 no.3
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• pp.329-334
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• 2010

The characteristics of nitrogen mineralization in upland soil was studied with 27-week incubation at $25^{\circ}C$. The used soils in this experiment were received six kinds of livestock manure compost each year for four years. Six different composts, which were chicken (CHM), pig (PIM), and cow (COM) manure composted without bulking agent, and chicken (CHMS), pig (PIMS), and cow (COMS) manure composted with sawdust as a bulking agent, were selected for this study. The first-order model was fit to the observed mineral nitrogen (N) vs incubation days using a non-linear regression procedure. The soil potential for N mineralization (No) of manure compost (CHM, PIM, and COM) treated soils were higher than those of the manure-sawdust compost (CHMS, PIMS, and COMS) treated soils. The No value of PIM applied soil was 15.0 mg 100 $g^{-1}$, which was the highest value among the treatments. The amount of N mineralized in compost applied soils ranged from 8.1% to 11.9% of the total N content in soils and increased with increasing total N content in soils. The organic matter content in compost applied soils were negatively correlated with No value (r = $-0.69^*$). Therefore, our result indicated that determination of N application rate in livestock manure compost applied soil should be based on total nitrogen content better than soil organic matter content.

• CELLMED
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• v.4 no.3
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• pp.19.1-19.6
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• 2014

The most important reason mentioned for the early discontinuation of breast feeding and introduction of supplementary bottles is Perceived Insufficient Milk (PIM), which is relatively common in women. This is of public health concern because the use of breast milk substitutes increases the risk of morbidity and mortality among infants in developing countries and shortens birth intervals. Thus, a literary search in classical text for aetiopathogenesis, symptoms and treatment of PIM were appraised to implement in contemporary era. The classical Unani texts viz., Al Qanon fit Tib (Canon of Medicine), Al Hawi (Continens Liber), Zakheera Kharzam Shahi, Tarjuma Kamilus Sana, Tibbe Akbar, Akseer Azam, and Kitabul Kulliyat were reviewed. Further certain galactogogue herbs which are in use since antiquity such as fenugreek, cotton seeds, cumin, asparagus, black cumin etc were explored in different search engines on website for proven galactogogue activity. The causes of PIM are abnormal temperament of body or breast, anaemia, anxiety, depression, malnutrition etc. The principle treatment is treating the cause viz., the temperament is corrected by diet and drugs in abnormal temperament, elimination of humour is required in dominance of humour etc. The aforementioned drugs are proven scientifically for their galactogogue activity. The classical texts are having valuable information regarding PIM, which can be implemented in present era. Aforementioned Unani drugs are proven scientifically for with their galactogogue effect, however, clinical trials are scarce. Therefore, further randomized controlled clinical trials are recommended.

• Transactions of Materials Processing
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• v.12 no.6
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• pp.521-528
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• 2003

Powder injection molding (PIM) uses the shaping advantage of injection molding but is applicable to metals and ceramics. This process combines a small quantity of polymer with an inorganic powder to form a feedstock that can be molded. After shaping, the polymeric binder is extracted and the powder is sintered, often to near-theoretical densities. According1y, PIM delivers structural materials in a shaping technology previously restricted to polymers. The process overcomes the shape limitations of traditional powder compaction, the costs of machining, the productivity limits of isostatic pressing and slip casting, and the defect and tolerance limitations of conventional casting. Since 1980s when major attention was given to PIM process, it has been widening the application area from small parts with complex shape and tailored properties to structural parts requiring strength and ductility as in automotive, military and medical industries.

• Molecules and Cells
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• v.44 no.7
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• pp.444-457
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• 2021

Although the mechanism of chronic myeloid leukemia (CML) initiation through BCR/ABL oncogene has been well characterized, CML cell differentiation into erythroid lineage cells remains poorly understood. Using CRISPR-Cas9 screening, we identify Chromobox 8 (CBX8) as a negative regulator of K562 cell differentiation into erythrocytes. CBX8 is degraded via proteasomal pathway during K562 cell differentiation, which activates the expression of erythroid differentiation-related genes that are repressed by CBX8 in the complex of PRC1. During the differentiation process, the serine/threonine-protein kinase PIM1 phosphorylates serine 196 on CBX8, which contributes to CBX8 reduction. When CD235A expression levels are analyzed, the result reveals that the knockdown of PIM1 inhibits K562 cell differentiation. We also identify TRIM28 as another interaction partner of CBX8 by proteomic analysis. Intriguingly, TRIM28 maintains protein stability of CBX8 and TRIM28 loss significantly induces proteasomal degradation of CBX8, resulting in an acceleration of erythroid differentiation. Here, we demonstrate the involvement of the CBX8-TRIM28 axis during CML cell differentiation, suggesting that CBX8 and TRIM28 are promising novel targets for CML research.

• Bulletin of the Korean Chemical Society
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• v.23 no.8
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• pp.1085-1088
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• 2002

Calix[6]arene having both carboxylic acid (1,3,5-) and carboxamide (2,4,6-) in an alternative way was synthesized. Transport rates of alkali and alkaline-earth metal ions were tested in bulk liquid membrane and polymer inclusion membrane. Ba2+ ion was found to give the highest transport rate among tested metal ions in both BLM and PIM systems. In PIM system, high durability (longer than 30 days) of the membrane was observed.

• International Journal of Knowledge Content Development & Technology
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• v.9 no.1
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• pp.19-42
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• 2019

This study examined activities involving the finding, organizing, managing, and re-finding of information by knowledge workers in Kuwait. This research also conducted a review of the tools needed for effective personal information management (PIM) and assessed perceptions about improving PIM through Internet use. Data were collected through semi-structured interviews conducted among 26 graduates of the Department of Information Studies at Kuwait University. These participants are currently employed in different sectors engaged in a variety of information-related activities. This study's findings indicated that participants gathered different types of information from a variety of sources. This information was stored using several devices and services, including desktop computers, shared drives, clouds, bookmarked websites, e-mail correspondence, and favorites lists. Participants organized information in personal folders according to categories such as subject/topic, time, project, document type, and geographical region. Preferred methods for information re-finding included searching by keyword and browsing through folders. Interviewees reported problems of information overload, fragmentation, and anxiety. Most were active in social media via mobile device, while some of them used Siri or Ask Google to retrieve information. Tools used for PIM included calendars, tasks, schedules, e-mail management tools, clouds, and social networking tools. Participants reported that the Internet helped with personal information management practices, but that some privacy issues arose in this context.