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Fully Analytic Approach to Evaluate Laser-induced Thermal Effects

  • Kim, Myungsoo;Kwon, Gyeong-Pil;Lee, Jinho
    • Current Optics and Photonics
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    • v.1 no.6
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    • pp.649-654
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    • 2017
  • In this communication, we present an expression to determine thermal lensing in isotropic materials. The heat equation is analytically solved when a Gaussian spatial laser beam profile is introduced to a cylindrical geometry of optics using a complete set of Bessel functions. This expression permits explicit calculation of variation of focal length induced by thermal lensing and allows thermal effects for various material parameters on the optics. We applied our model to a high absorption material (Ti:sapphire) and also transparent material (thallium garnet or TGG) and found that the thermal lensing can be reduced more than 4 times by adjusting the laser beam waist and optics dimensions. Our analysis is completely general and applicable to any optical system.

Physiologically Based Pharmacokinetic (PBPK) Modeling in Neurotoxicology

  • Kim, Chung-Sim
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.10a
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    • pp.135-136
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    • 1995
  • Resent advances in computer technology have introduced a sophisticated capability for computing the biological fate of toxicants in a biological system. This methodology, which has drastically altered risk assessment skill in toxicology, is designed using all the mechanistic information, and all claim better accuracy with extrapolating capability Iron animal to people than conventional pharmacokinetic methods. Biologically based mathematical models in which the specific mechanistic steps governing tissue disposition(pharmacokinetics) and toxic action (pharmacodynamics) of chemicals are constructed in quantitative terms by a set of equations loading to prediction of the outcome of specific toxicological experiments by computer simulation. pharmacokinetic and pharmacodynamic models are useful in risk assessment because their mechanistic biological basis permits the high-to-low dose, route to route and interspecies extrapolation of the tissue disposition and toxic action of chemicals.

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Heat Treatment Analysis on Low-Alloy Steel (저합금강 소재의 열처리해석 기술개발)

  • Choi Y. S.;Kwak S. Y.;Choi J. K.;Kim J. T.
    • Transactions of Materials Processing
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    • v.14 no.3 s.75
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    • pp.215-223
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    • 2005
  • A numerical analysis program is developed by FDM scheme for the prediction of microstructural transformation during heat treatment of steels. In this study, multi-phase model was used fur description of diffusional austenite transformations in low-alloy hypoeutectoid steels during cooling after austenitization. A fundamental property of the model consisting of coupled differential equations is that by taking into account the rate of austenite grain growth, it permits the prediction of the progress of ferrite, pearlite, and bainite transformations simultaneously during quenching and estimate the amount of martensite also by using K-M eq. In order to simulate the microstructural evolution during tempering process, another Avrami-type eq. was adopted and method for vickers hardness prediction was also proposed. To verify the developed program, the calculated results are compared with experimental ones of casting product. Based on these results, newly designed heat treatment process is proposed and it was proved to be effective for industry.

Study About a New Propulsion System Using CRP( I ) (Flow interaction mechanism of a counter-rotating propeller) (CRP를 사용한 추진기관에 관한 연구( I ) (CRP의 유동상호작용에 관하여))

  • 정진덕;이동호
    • Journal of the Korean Society of Safety
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    • v.10 no.1
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    • pp.3-8
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    • 1995
  • The anemometer measurements were obtained from stationary hot-film probe mounted between the forward and rear rotors of a model CRP which rotated the forward and different directions. Data collection was done at several locations between rotors. To establish rotor-rotor interaction flow mechanism that contributes noise increasement of the CRP, methods of simple and the double condition-at sampling have been developed. The former uses to find similarity of the wake the later fixes the forward rotor position in time or space and permits averaging the mean wake at any fixed rotor angular location. The variation of the forward wake Is strongly depending upon the rear rotor location.

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Applying PKI for Internet Voting System

  • Kim, Jinho;Kim, Kwangjo;Lee, Byoungcheon
    • Proceedings of the Korea Institutes of Information Security and Cryptology Conference
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    • 2001.11a
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    • pp.318-321
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    • 2001
  • We have designed an Internet voting system applicable for worldwide voting which is based on Ohkubo et. al,'s scheme[9] combined with Public Key Infrastructure (PKI). To the best of our knowledge, this is the first trial to serve secure Internet voting system to the world. In our system, voter's privacy is guaranteed by using blind signature and mix-net, and robustness is provided through the threshold encryption scheme. By employing Java technology, we propose a way of typical implementation for internet voting system. Furthermore, PKI permits worldwide key distribution and achieve “one certificate/one vote” policy. Therefore, anyone can participate in the voting if he gets a certificate from Certificate Authority (CA). By the joint work between Korean and Japanese teams, the implementation aims to select MVPs in 2002 FIFA World Cup Korea-Japan$\^$TM/ in easy and friendly manner for any Internet user to participate and enjoy Internet voting.

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A Generic Time-resolved Fluorescence Assay for Serine/threonine Kinase Activity: Application to Cdc7/Dbf4

  • Xu, Kui;Stern, Alvin S.;Levin, Wayne;Chua, Anne;Vassilev, Lyubomir T.
    • BMB Reports
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    • v.36 no.4
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    • pp.421-425
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    • 2003
  • The serine/threonine protein kinase family is a large and diverse group of enzymes that are involved in the regulation of multiple cellular pathways. Elevated kinase activity has been implicated in many diseases and frequently targeted for the development of pharmacological inhibitors. Therefore, non-radioactive antibody-based kinase assays that allow high throughput screening of compound libraries have been developed. However, they require a generation of antibodies against the phosphorylated form of a specific substrate. We report here a time-resolved fluorescence assay platform that utilizes a commercially-available generic anti-phosphothreonine antibody and permits assaying kinases that are able to phosporylate threonin residues on protein substrates. Using this approach, we developed an assay for Cdc7/Dbf4 kinase activity, determined the $K_m$ for ATP, and identified rottlerin as a non-ATP competitive inhibitor of this enzyme.

Studying immune system using imaging and microfabrication (생체영상과 미세가공을 이용한 면역 시스템 연구)

  • Doh, Jun-Sang
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.1446-1449
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    • 2008
  • Immune system is composed of multiple cells with distinct functions, and immune responses are orchestrated by complex and dynamic cell-cell interactions. Therefore, each cell behavior and function should be understood under right spatio-temporal context. Studying such complexity and dynamics has been challenging with conventional biological tools. Recent development of new technologies such as state of art imaging instruments and microfabrication techniques compatible with biological systems have provided many exciting opportunities to dissect complex and dynamic immune cell interactions; new microscopy techniques enable us to observe stunning dynamics of immune system in real time. Microfabrication permits us to manipulate microenvironments governing molecular/cellular dynamics of immune cells to study detailed mechanisms of phenomena observed by microscopy. Also, microfabrication can be used to engineer microenvironments optimal for specific imaging techniques. In this presentation, I am going to present an example of how these two techniques can be combined to tackle challenging problems in immunology. Obviously, this strategy can readily be applied to many different fields of biology other than immunology.

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INVARIANT MEASURE AND THE EULER CHARACTERISTIC OF PROJECTIVELY ELAT MANIFOLDS

  • Jo, Kyeong-Hee;Kim, Hyuk
    • Journal of the Korean Mathematical Society
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    • v.40 no.1
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    • pp.109-128
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    • 2003
  • In this paper, we show that the Euler characteristic of an even dimensional closed projectively flat manifold is equal to the total measure which is induced from a probability Borel measure on RP$^{n}$ invariant under the holonomy action, and then discuss its consequences and applications. As an application, we show that the Chen's conjecture is true for a closed affinely flat manifold whose holonomy group action permits an invariant probability Borel measure on RP$^{n}$ ; that is, such a closed affinly flat manifold has a vanishing Euler characteristic.

Passivity-based Controller Design for Induction Motor Driven by Doubly-fed Induction Generator (이중권선 유도발전기로 구동되는 유도전동기의 수동성기반제어기 설계)

  • Lee S.C.;Kim J.H.
    • Proceedings of the KIPE Conference
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    • 2003.07b
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    • pp.639-643
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    • 2003
  • We are interested in this paper on the control of an electromechanical system consisting of a doubly-fed induction generator(DFIG), driven by a prime mover that can supply or extract mechanical power, e.g., a flywheel inertia, and an induction motor(IM). The stator of the Induction machine is connected to the stator of the generator whose rotor voltage is regulated by a bidirectional converter. The main interest of this configuration is that it permits a bidirectional power flow between the motor, which may operate in regenerative mode, and the generator We propose a passivity-based controller to regulate the motor mechanical speed. Since this kind of controllers achieve stabilization via energy balancing, regulation of the power flow in the system is naturally incorporated. Simulation results are presented to illustrate the main points of our paper.

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Multivariable Controller Design for Nuclear Power Plant Using INA Method (INA 법을 이용한 원자력 발전소의 다변수 제어기 설계)

  • Dong-Hwa Kim;Suk-Kyo Hong
    • The Transactions of the Korean Institute of Electrical Engineers
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    • v.39 no.10
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    • pp.1086-1097
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    • 1990
  • The design of multivariable control systems using the Inverse Nyquist Array method is described in this paper. The INA is a simple design technique, which permits a designer to achieve his objectives for a controller specification in a step-by-step fashion using Gershgorin band and Ostrowski circle. The application to a multivariable system of CANDU nuclear power plant with 5 inputs, 8 outputs, and 24 state variables is reviewed and the simulation shows satisfactory results.