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Myocardial Blood Flow Quantified by Low-Dose Dynamic CT Myocardial Perfusion Imaging Is Associated with Peak Troponin Level and Impaired Left Ventricle Function in Patients with ST-Elevated Myocardial Infarction

  • Jingwei Pan;Mingyuan Yuan;Mengmeng Yu;Yajie Gao;Chengxing Shen;Yining Wang;Bin Lu;Jiayin Zhang
    • Korean Journal of Radiology
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    • v.20 no.5
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    • pp.709-718
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    • 2019
  • Objective: To investigate the association of myocardial blood flow (MBF) quantified by dynamic computed tomography (CT) myocardial perfusion imaging (MPI) with troponin level and left ventricle (LV) function in patients with ST-segment elevated myocardial infarction (STEMI). Materials and Methods: Thirty-five STEMI patients who successfully had undergone reperfusion treatment within 1 week of their infarction were consecutively enrolled. All patients were referred for dynamic CT-MPI. Serial high-sensitivity troponin T (hs-TnT) levels and left ventricular ejection fraction (LVEF) measured by echocardiography were recorded. Twenty-six patients with 427 segments were included for analysis. Various quantitative parameters derived from dynamic CT-MPI were analyzed to determine if there was a correlation between hs-TnT levels and LVEF on admission and again at the 6-month mark. Results: The mean radiation dose for dynamic CT-MPI was 3.2 ± 1.1 mSv. Infarcted territories had significantly lower MBF (30.5 ± 7.4 mL/min/100 mL versus 73.4 ± 8.1 mL/min/100 mL, p < 0.001) and myocardial blood volume (MBV) (2.8 ± 0.9 mL/100 mL versus 4.2 ± 1.1 mL/100 mL, p = 0.044) compared with those of reference territories. MBF showed the best correlation with the level of peak hs-TnT (r = -0.682, p < 0.001), and MBV showed a moderate correlation with the level of peak hs-TnT (r = -0.437, p = 0.026); however, the other parameters did not show any significant correlation with hs-TnT levels. As for the association with LV function, only MBF was significantly correlated with LVEF at the time of admission (r = 0.469, p = 0.016) and at 6 months (r = 0.585, p = 0.001). Conclusion: MBF quantified by dynamic CT-MPI is significantly inversely correlated with the level of peak hs-TnT. In addition, patients with lower MBF tended to have impaired LV function at the time of their admission and at 6 months.

ON FINSLER METRICS OF CONSTANT S-CURVATURE

  • Mo, Xiaohuan;Wang, Xiaoyang
    • Bulletin of the Korean Mathematical Society
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    • v.50 no.2
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    • pp.639-648
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    • 2013
  • In this paper, we study Finsler metrics of constant S-curvature. First we produce infinitely many Randers metrics with non-zero (constant) S-curvature which have vanishing H-curvature. They are counterexamples to Theorem 1.2 in [20]. Then we show that the existence of (${\alpha}$, ${\beta}$)-metrics with arbitrary constant S-curvature in each dimension which is not Randers type by extending Li-Shen' construction.

PACKING DIMENSIONS OF GENERALIZED RANDOM MORAN SETS

  • Tong, Xin;Yu, Yue-Li;Zhao, Xiao-Jun
    • Journal of the Korean Mathematical Society
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    • v.51 no.5
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    • pp.1075-1088
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    • 2014
  • We consider random fractal sets with random recursive constructions in which the contracting vectors have different distributions at different stages. We prove that the random fractal associated with such construction has a constant packing dimension almost surely and give an explicit formula to determine it.

ON A CLASS OF LOCALLY PROJECTIVELY FLAT GENERAL (α, β)-METRICS

  • Mo, Xiaohuan;Zhu, Hongmei
    • Bulletin of the Korean Mathematical Society
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    • v.54 no.4
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    • pp.1293-1307
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    • 2017
  • General (${\alpha},{\beta}$)-metrics form a rich class of Finsler metrics. They include many important Finsler metrics, such as Randers metrics, square metrics and spherically symmetric metrics. In this paper, we find equations which are necessary and sufficient conditions for such Finsler metric to be locally projectively flat. By solving these equations, we obtain all of locally projectively flat general (${\alpha},{\beta}$)-metrics under certain condition. Finally, we manufacture explicitly new locally projectively flat Finsler metrics.

Saturation impulses for dynamically loaded structures with finite-deflections

  • Zhao, Ya-Pu;Yu, T.X.;Fang, J.
    • Structural Engineering and Mechanics
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    • v.3 no.6
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    • pp.583-592
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    • 1995
  • The concept of "Saturation Impulse" for rigid, perfectly plastic structures with finite-deflections subjected to dynamic loading was put forward by Zhao, Yu and Fang (1994a). This paper extends the concept of Saturation Impulse to the analysis of structures such as simply supported circular plates, simply supported and fully clamped square plates, and cylindrical shells subjected to rectangular pressure pulses in the medium load range. Both upper and lower bounds of nondimensional saturation impulses are presented.

GLOBAL W1,2p ESTIMATES FOR NONDIVERGENCE PARABOLIC OPERATORS WITH POTENTIALS SATISFYING A REVERSE HÖLDER CONDITION

  • Pan, Guixia;Tang, Lin
    • Journal of the Korean Mathematical Society
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    • v.54 no.5
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    • pp.1357-1377
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    • 2017
  • In this article, we first give the $L^p$ boundedness of the operator $D^2L^{-1}$ with BMO coefficients and a potential V satisfying an appropriate reverse $H{\ddot{o}}lder$ condition, then obtain global $W^{1,2}_p$ estimates for the nondivergence parabolic operator L with VMO coefficients and a potential V satisfying an appropriate reverse $H{\ddot{o}}lder$ condition.

A Value of the plants Seowon in the Chosun dynasty through the O.U.V (O.U.V(Outstanding Universal Value)를 통한 조선시대 서원 식물의 가치)

  • Lee, Won Ho;Lee, So Hyun;Shin, Hyun Sil
    • Proceedings of the Korea Contents Association Conference
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    • 2013.05a
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    • pp.133-134
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    • 2013
  • 현재 세계문화유산 등재 추진 중에 있는 전국 서원 6개소 조경유적의 구성요소를 도출하고, 이를 기초로 식물유산과 관련하여 진정성 평가항목 7가지에 부합하는 사례를 분석한다. 이를 통하여 과연 유산으로 등재될 만한 가치를 지니고 있는지 판단 여부에 대한 기초정보를 제공하고자 한다.

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Griseusin C, a Novel Quinone Derivative from a Marine-Derived Fungus Penicillium sp.

  • Li, Xiang;Zheng, Yinan;Sattler, Isabel;Lin, Wenhan
    • Archives of Pharmacal Research
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    • v.29 no.11
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    • pp.942-945
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    • 2006
  • A novel quinone derivative, Griseusin C (1), along with a known quinone, Naphthoquinone C (2), was isolated from the lyophilized culture broth of the marine-derived fungus Penicillium sp. The structures were elucidated on the basis of extensive 1D-and 2D-NMR, as well as HRESIMS, spectroscopic analysis. The relative stereochemistries of the compounds were assessed by NOESY analysis.