• Title/Summary/Keyword: Park Yoo-jeon

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Lipid-lowering and Antioxidant Effects of Curcuma Radix in Poloxamer 407-induced Hyperlipidemia Model Rat Models

  • Park, So-Ae;Jo, Hyun-Kyung;Yoo, Ho-Ryong;Kim, Yoon-Sik;Seol, In-Chon;An, Joung-Jo
    • The Journal of Internal Korean Medicine
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    • v.32 no.2
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    • pp.243-258
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    • 2011
  • Objectives : This study investigated the hypolipidemic and antioxidant effects of Curcuma radix using a rat model induced by poloxamer 407 injection. Methods : Serum lipid parameters and oxidative stress-associated biomarkers were determined. Additionally, hepatic cholesterol and triglyceride as well as lipid metabolism-associated gene expressions were observed in hepatic tissue. Results : 1. Curcuma radix ameliorated elevation of serum cholesterol, triglyceride, LDL-cholesterol, MDA, hepatic cholesterol level, and reduction of serum TAC, SOD, GSH, GSH-reductase level. 2. Curcuma radix augmented up-regulated ACAT gene expression. 3. Curcuma radix almost completely ameliorated down-regulated CYP-7A1 but up-regulated HMG-CoA gene expression. Conclusions : The hypolipidemic and antioxidant properties of Curcuma radix were evidenced. This study provides a scientific basis for the clinical application of Curcuma radix and development of hypolipidemics using this herb in the future.

Two-cases of Reduction of Side Effects of Surgery and Radiation Therapy in Retroperitoneal Liposarcoma Treated with Traditional Korean Medicine (한방 치료로 수술 및 방사선 치료 후 부작용 완화를 이룬 후복막 지방육종 환자 2례의 보고)

  • Bae, Kyeore;Kim, Ji-Hye;Park, Ji-Hye;Park, So-jung;Kang, Hwi-joong;Cho, Chong-kwan;Yoo, Hwa-seung
    • Journal of Korean Traditional Oncology
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    • v.20 no.2
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    • pp.37-49
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    • 2015
  • Objectives : Retroperitoneal liposarcoma (RPS) is a rare solid tumor and has a high recurrence rate after surgery. New complementary and alternative medicine is required to manage symptoms of RPS and side effects of surgery, chemotherapy and radiation therapy. The purpose of this case report is to report two cases of reduction of side effects of surgery and radiation therapy in RPS treated with Wheel Balanced Therapy (WBT) which is a traditional Korean medicine treatment program for patients with cancer. Methods : Two patients with RPS were treated with WBT. Each of patients received personalized WBT schedule including acupuncture. The changes in clinical and laboratory findings were evaluated. Results : The symptoms of patients were improved after about 2 weeks hospitalization. Conclusions : This case report suggests that WBT has a potential to treat side effects of surgery and radiation therapy in patients with RPS. Further rigorous studies are necessary to investigate the therapeutic effects of WBT on RPS.

MARS-PD: Meridian Activation Remedy System for Parkinson's Disease

  • Miso S. Park;Chan-young Kim;In-woo Choi;In-cheol Chae;Wangjung Hur;SangSoo Park;Horyong Yoo
    • The Journal of Internal Korean Medicine
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    • v.44 no.1
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    • pp.1-11
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    • 2023
  • Objective: There are currently no disease-modifying medications or definite long-term sustainable interventions for patients with Parkinson's disease (PD), indicating an unmet treatment need. Our goal was to create a long-term sustainable intervention for PD patients that can be used in Korean medicine clinics. Methods: The Meridian Activation Remedy System (MARS) was created to stimulate a patient's 12 meridians and sinew channels using a combination of acupoint stimulation and exercise. The acupoints and motions used in MARS were selected through literature studies and expert advice. The methodologies were refined using observational and case studies. With slow and fast movements, the MARS intervention was intended to activate both slow- and fast-twitch muscle fibers. Intradermal acupuncture and motion that shift the center of gravity were employed to enhance the patient's balance and proprioception. In addition, the intervention included alternating movement exercises to address the complex cognitive decline commonly occurring in PD patients. Results: The following acupoints were chosen for the MARS intervention: bilateral Hegu (LI4), Houxi (SI3), Waiguan (TE5), Neiguan (PC6), Zhongchong (PC9), Yuji (LU10), Zusanli (ST36), Yanglingquan (GB34), Taichong (LR3), Kunlun (BL60), and Taixi (KI3). We also developed actions that can stimulate the body's 12 meridians. Conclusion: We developed the MARS intervention, which combines acupuncture and exercise, to address the unmet therapeutic needs of PD patients. We hope that with additional research, the MARS intervention can be set as an effective therapeutic program for PD patients.

Case Study on Advanced Thymic Cancer Treated with Wheel Balanced Therapy (수레바퀴 암치료법을 시행한 흉선암 환자에 대한 증례보고)

  • Lee, Jong-Ho;Park, Jae-Woo;Yoo, Hwa-Seung;Cho, Chong-Kwan;Lee, Yeon-Weol
    • The Journal of Internal Korean Medicine
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    • v.32 no.3
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    • pp.458-464
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    • 2011
  • Background : Advanced thymic cancer still remains as an intractable disease. The survival rate of advanced thymic cancer could be increased through chemotherapy and radiation, but the results have not been satisfactory. Objectives : To see whether wheel balanced therapy (WBT) has the therapeutic effects or not on advanced thymic cancer patient. Methods : A patient diagnosed with progression of thymic carcinoma with pleura metastasis visited the East-West Cancer Center (EWCC) on Feb 9th, 2011. The patient was treated with WBT for a period of 9 weeks from Feb 9th to Apr 16th. She stayed 6 weeks in hospital and took oriental medicine prescribed by EWCC. Computed tomography (CT) and blood test were used to evaluate the disease progression of the patient. Results : Mass of chest CT was stable for 2 months. The patient's quality of life improved during her hospital stay. Conclusions : This case study supports WBT may have efficacy in treating advanced thymic cancer patients.

Case Report: Changes in Magnetic Resonance Imaging in Lumbar Disc Herniation Treated with Korean Medicine (한의원에서 도침치료로 영상의학적 소견을 호전시킨 요추 추간판 탈출증 증례 1례)

  • Park, Sang-kyu;Kim, Yoon-sik;Jo, Hyun-kyung;Yoo, Ho-ryong;Seol, In-chan
    • The Journal of Internal Korean Medicine
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    • v.39 no.5
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    • pp.863-869
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    • 2018
  • Objectives: The purpose of this case study was to report the effectiveness of Korean medicine treatment on severe lumbar disc herniation patient diagnosed by magnetic resonance imaging (MRI). Methods: The patient was treated with complex Korean medicine treatment, including acupuncture, pharmacopuncture, acupotomy, and Chu-na treatment. The treatment effect was evaluated by a Numerical Rating Scale (NRS), and MRI. Results: After the treatment, the NRS score of pain intensity was reduced from severe to mild degree. The volume of extruded disc in MRI images was clearly reduced. Conclusion: Korean medicine treatment might be effective in patients with lumbar disc herniation.

A Case Report of a Stage IV Non-small Cell Lung Cancer Patient Treated with Modified Yieum-jeon Showing Improvement in Malignant Pleural Effusion and other Respiratory Symptoms (비소세포성 폐암 4기 환자의 악성흉수로 인한 증상이 이음전가미방으로 호전된 1례)

  • Park, So-Jung;Kang, Hwi-Joong;Lee, Yeon-Weol;Cho, Chong-Kwan;Yoo, Hwa-Seung
    • The Journal of Internal Korean Medicine
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    • v.35 no.3
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    • pp.366-372
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    • 2014
  • Objectives: This is a report of a case of a stage IV non-small-cell lung cancer (NSCLC) patient whose malignant pleural effusion & respiratory symptoms have been relieved with Korean medicinal prescription, modified Yieum-jeon. Methods: A 56-year-old male diagnosed with stage IV NSCLC suffering malignant pleural effusion with complaints of cough, sputum, bilateral leg edema, dysphagia, post neck and left scapular pain was treated with modified Yieum-jeon and acupuncture during 16days. After treatment, blood lab and chest X-ray were used to follow the condition of malignant pleural effusion & pulmonary symptoms. Results: Malignant pleural effusion and pulmonary symptoms were improved with modified Yieum-jeon intake without any related adverse side effects. Conclusions: This study suggests Yieum-jeon may play a positive role in improving the malignant pleural effusion symptoms in advanced lung cancer cases.