• Title/Summary/Keyword: PDM

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Study on the Cell Adhesion of Breast Cancer Cells using Nano/Micro Patterning PDMS (나노/마이크로 패턴 PDMS를 이용한 유방암 세포의 부착에 관한 연구)

  • Kwak, Do Hoon;Kim, Woo Cheol;Jin, Hee Won;Yun, Wan Su;Park, Sanghyo;Key, Jaehong
    • Journal of Biomedical Engineering Research
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    • v.40 no.5
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    • pp.165-170
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    • 2019
  • Cancer cells are different from normal cells in terms of life cycle, behavior, and growth patterns. Cancer cells can migrate freely in the body through blood vessels and lymph nodes. The cancer cells easily interact with various substrates including extracellular matrix and vessels and they can differentiate in the new environment. However, it is not well known about the adhesion preference of cancer cells on the substrate and the mechanism of their interaction. In this study, we prepared the nano-, micro-patterned substrates using E-beam lithography techniques. MCF-7 cells were tested on the substrates to find out their adhesion preference. The substrates were made by polydimethylsiloxane (PDMS) with specific patterns including pillars with a diameter of 500 nm, 700 nm, $3{\mu}m$ and $5{\mu}m$. MCF-7 cells were seeded on the substrates and incubated for 24 hours. As a result, this study clearly demonstrated that the MCF-7 cells preferred 700 nm patterning.

Study for coping with water shortage analysis: Imjin-River Basin in dry season (임진강 유역 갈수기 물 부족 원인 분석에 따른 대응 방안 연구)

  • JANG, Suk-Hwan;LEE, Jae-Kyung;LEE, Hyo-Sang;OH, Ji-Hwan
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.261-261
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    • 2016
  • 임진강 유역은 우리나라와 북한과의 접경지역에 속하는 유역으로서 임진강은 북한에서 발원하여 남한으로 흘러 한강으로 유입되는 공유하천으로 볼 수 있다. 본 연구 유역은 이수, 치수, 수질, 환경 측면에서 타 유역에 비해 불안요소가 많은 지역이므로 남북한의 관계 개선을 통한 효과적인 대책 수립에서 공동의 노력이 필요한 지역이라 할 수 있다. 과거에 집중호우와 태풍의 영향 등으로 인하여 많은 피해로 인하여 이에 따른 대책과 많은 계획 등이 수립되었고, 북한의 무단방류에 따른 사고로 인하여 피해로 인하여 이를 극복하고, 홍수를 조절하는 목적으로 군남홍수조절지, 한탄강홍수조절댐을 건설하여 홍수에 따른 선제적 대응과 주민 피해 등을 방지하고자 하였다. 그러나 최근 경기북부를 포함한 임진강 유역의 가뭄으로 인한 유량의 감소로 인하여, 2014~2015년의 파주 장단반도 일대의 농업용수 부족과 하구의 조위, 즉 염도에 의한 영향으로 하류부 급수 불량 등 이수적 측면에서 주민들의 피해 문제가 속출하고 있는 실정이다. 위와 같은 배경을 바탕으로 본 연구에서는 임진강 유역에 위치한 기상 수문관측자료(2000년~2015년)를 이용하여 다음 내용을 연구하였다. 첫째로 수문기상인자들의 경향성 분석을 통하여 임진강 유역의 유량 감소 원인을 파악하였으며, 수문기상인자들의 감소에 따른 영향과 북한 댐건설에 따른 유역변경 영향에 대하여 분석을 수행하였다. 전체적으로 임진강 유역의 유량은 감소추세에 있으며, 북한 댐건설의 영향이 있는 것으로 파악되었다. 또한 최근 2014년과 2015년의 유량 감소는 강수량의 감소 영향이 큰 것으로 나타났다. 두 번째로 북한 댐건설에 의한 영향을 살펴보기 위해 임진강 상류를 대상으로 하천유출모형인 PDM을 이용하여 장기유출모의를 수행하였으며, 모의결과 북한 댐건설에 의해 유출특성이 변하였음을 확인하였다. 세 번째로 임진강 유역 갈수량을 추정하고 물 부족량 및 필요수량을 분석하였다. 분석결과, 북한 댐건설 이후를 기준으로 물 부족량이 발생하였으며, 이에 필요한 필요 수량을 제안하였다. 또한 최근 2014년과 2015년과 같은 비상시에 대한 필요 수량도 제안하였다. 마지막으로 앞서 제안한 필요 수량을 확보하기 위해 기존댐 담수 및 연계운영, 신규 수자원 확보 방안, 남북 공유하천 공동 관리 방안 등의 대응방안을 제안하였다.

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Development of Parametric Design Tool for Offshore Plant Cable Tray Using PML (프로그램 매크로언어를 이용한 해양 플랜트 케이블 트레이의 파라메트릭 설계 도구 개발)

  • Kim, Hyun-Cheol
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.632-637
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    • 2019
  • The cable tray design of an offshore plant production design is to optimally arrange the 3D modeling so that the cable can be installed without interfering with the structural members and various outfit equipment, and it is performed using a PDMS (Plant design management system), which is a 3D CAD system for an offshore plant layout. This study reviewed the development of PML (Programmable macro language) for a PDMS supporting offshore plant cable tray design and examined the efficiency compared to the existing method. Cable tray design PML developed in this paper enables fully parametric design using electrical outfit template library, allowing a rapid response to frequent modifications due to design changes and minimizing repetitive work fatigue by reflecting the accumulated design experience. In addition, the developed system was applied to the offshore plant structure module and it improved the work efficiency by more than 50% compared to the existing method.

Preparation of PDMS Surface Modifier Using Silane-Functionalized Polymer Precursor Manufacture and Their Properties (실란 기능화 아크릴 고분자 전구체를 이용한 PDMS 표면 개질제 제조 및 표면 물성)

  • Shin, Jae-Hyeon;Kim, Nahae;Kim, Juyoung
    • Journal of Adhesion and Interface
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    • v.19 no.4
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    • pp.154-162
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    • 2018
  • Plasma treatment and corona treatment have been used for surface modification of polydimethylsiloxane (PDMS) film by activating its surface with the -OH group. Adhesion promoter or coupling agent was also used to improve adhesion of PDMS film with various materials. However, obtained hydrophilicity onto the surface of PDMS films with those processes was transient and vulnerable. In this study, a new alkoxysilane-functionalized acrylic polymer precursor was first synthesized by copolymerization process, and then was reacted with HO-terminated PDMS through condensation reaction to prepare a new surface modifier for PDMS film. The structure and molecular weight of the prepared surface modifier were confirmed by 1H-NMR and GPC measurement. Surface properties of surface modifier-coated PDMS films were also investigated by using XPS, ATR and WCA analysis. The adhesion between the PDMS film and the surface modifier was tested using cross-cut test.

Comparison and analysis of compression algorithms to improve transmission efficiency of manufacturing data (제조 현장 데이터 전송효율 향상을 위한 압축 알고리즘 비교 및 분석)

  • Lee, Min Jeong;Oh, Sung Bhin;Kim, Jin Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.26 no.1
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    • pp.94-103
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    • 2022
  • As a large amount of data generated by sensors or devices at the manufacturing site is transmitted to the server or client, problems arise in network processing time delay and storage resource cost increase. To solve this problem, considering the manufacturing site, where real-time responsiveness and non-disruptive processes are essential, QRC (Quotient Remainder Compression) and BL_beta compression algorithms that enable real-time and lossless compression were applied to actual manufacturing site sensor data for the first time. As a result of the experiment, BL_beta had a higher compression rate than QRC. As a result of experimenting with the same data by slightly adjusting the data size of QRC, the compression rate of the QRC algorithm with the adjusted data size was 35.48% and 20.3% higher than the existing QRC and BL_beta compression algorithms.

Physicochemical Characteristics of UV/Ozone Treated Polydimethylsiloxane(PDMS) Wrinkle Structures (UV/Ozone 처리를 통한 Polydimethylsiloxane(PDMS) 주름 구조의 물리화학적 특성 분석)

  • Park, Hong-Gyu;Park, Seung-Yub
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.15 no.5
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    • pp.321-327
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    • 2022
  • In this paper, a wrinkled structure was formed on the PDMS surface through UV/Ozone treatment, and the wrinkle structure formation mechanism was revealed through physicochemical characterization. A wrinkle structure was formed on the PDMS surface through UV/Ozone treatment for 30 min, and periodic wrinkle formation on the PDMS surface was confirmed by cross-sectional imaging of the scanning electron microscope. In addition, through x-ray photoelectron spectroscopy spectral analysis, it was confirmed that the silica-like-surface of SiOx on the PDMS surface was formed by UV/Ozone. The results of this study not only improve the understanding of the mechanism of wrinkle structure formation on the PDMS surface by UV/Ozone treatment, but also can be used as a basic study to adjust the amplitude and period of the wrinkle structure according to UV/Ozone irradiation conditions in the future.contact angles and the surface energies of FSAMs, it was confirmed that pretilt angles of LC molecules increased according to the alkyl chain length. High optical transparency and uniform homeotropic LC alignment characteristics of FSAMs showed the possibility of FSAMs as an LC alignment layers.

A Study on the Balance of Stroke Patients According to Kneeling Squat Exercise and Standing Squat Exercise Positions (무릎스쿼트 운동과 스쿼트 운동 자세에 따른 뇌졸중 환자의 균형 비교 연구)

  • Go, Gwan-Hyeok;Kim, Byeong-Jo
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.4
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    • pp.1-9
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    • 2022
  • Purpose : The purpose of this research is to propose a more efficient exercising method by measuring and comparing the movement of center of pressure (COP) while hemiplegic stroke patients perform kneeling squat exercise and squat exercise. Methods : 17 hemiplegic stroke patients were instructed to perform kneeling squat exercises and squat exercises, and the research was designed as a cross-over study. For data collection, a pressure distribution measurement platform (PDM) was used to measure the movement area, length, speed, and distance from the center of the X-axis of center of pressure. The data was then analyzed through a paired t-test. Results : Kneeling squat exercises have been found to have a significantly smaller center of pressure movement area compared to that of squat exercise(p<.001), and the center of pressure movement length of kneeing squat exercise has also been found to be relatively shorter (p<.001). Moreover, kneeling squat exercises have been found to have a significantly slower center of pressure movement speed than squat exercise (p<.001), and kneeing squat exercise center of pressure movement distance from the center of the X-axis has been found to be significantly small (p<.001). Conclusion : Kneeling squat exercises have significantly decreased amounts of center of pressure movement area, distance, and speed compared to squat exercises. Also, the center of pressure movement distance from the center of the X-axis was relatively closer. This result seems to derive from patients performing their motions with wide base surfaces while being refrained from using unstable ankle joints during kneeing squat exercise. Therefore, it can be concluded that kneeing squat exercises show relatively balanced center of pressure movements between the paralyzed and non-paralyzed sides because kneeling squats show smaller shakes in the center of pressure.

Visual Tracking Technique Based on Projective Modular Active Shape Model (투영적 모듈화 능동 형태 모델에 기반한 영상 추적 기법)

  • Kim, Won
    • Journal of the Korea Society for Simulation
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    • v.18 no.2
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    • pp.77-89
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    • 2009
  • Visual tracking technique is one of the essential things which are very important in the major fields of modern society. While contour tracking is especially necessary technique in the aspect of its fast performance with target's external contour information, it sometimes fails to track target motion because it is affected by the surrounding edges around target and weak egdes on the target boundary. To overcome these weak points, in this research it is suggested that PDMs can be obtained by generating the virtual 6-DOF motions of the mobile robot with a CCD camera and the image tracking system which is robust to the local minima around the target can be configured by constructing Active Shape Model in modular base. To show the effectiveness of the proposed method, the experiment is performed on the image stream obtained by a real mobile robot and the better performance is confirmed by comparing the experimental results with the ones of other major tracking techniques.

Advanced Work Packaging (AWP) in Practice: Variables for Theory and Implementation

  • Jung, Youngsoo;Jeong, Yeheun;Lee, Yunsub;Kang, Seunghee;Shin, Younghwan;Kim, Youngtae
    • International conference on construction engineering and project management
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    • 2020.12a
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    • pp.201-206
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    • 2020
  • Diversification of project delivery methods (PDM) under ever-changing construction business environment has significantly changed the role of project participants. Active efforts to effectively sharing the roles and responsibilities have been observed in the project management offices (PMOs) among owner/operator organizations as well as engineering, procurement, construction and maintenance (EPCM) firms. In order for being effective in a holistic way throughout the project life-cycle, a PMO needs to have 'adequate management skills' as well as 'essential technical capabilities' in cooperating with many different participants. One of the well-known examples of the PMO's tool to support these skills and capabilities is the effective 'work packaging (WP)' that serves as a common basis integrating all relevant information in a structured manner. In an attempt to enhance the construction productivity, the concept of 'advanced work packing (AWP)' has been introduced by Construction Industry Institute (CII). The AWP enables productivity to be improved by early planning of construction packages in the design phase "with the end in mind". The purpose of this study is to identify and evaluate the 'variables' of advanced work packing (AWP) for life-cycle information integration. Firstly, an extended concept of advanced WP based on the CII AWP was defined in order to comprehend many different issues of business functions (e.g. cost, schedule, quality, etc.). A structured list of major components and variables of AWP were then identified and examined for practical viability with real-world examples. Strategic fits and managerial effectiveness were stressed throughout the analyses. Findings, implications and lessons learned are briefly discussed as well.

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An Ultra-thin IR Cut-off Filter Based on Nanostructures (나노구조 기반 초박형 적외선 차단 필터)

  • Hyundo Yang;Jong-Kwon Lee
    • Korean Journal of Optics and Photonics
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    • v.35 no.1
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    • pp.24-29
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    • 2024
  • We propose a hyperbolic metastructure based on a nanopatterned metal (Ag)-dielectric (PDMS) multilayer and report on its performance in an infrared (IR) cut-off filter for imaging devices. By optimizing the size of the square-shaped Ag nanopattern and the thickness of PDMS surrounding the Ag nanopattern, the proposed IR cut-off filter blocks 99% of light in the 0.70-1.01 ㎛ wavelength band while maintaining a high transmittance of over 94% in the visible region. Here, the cut-off wavelength band starts at a region above the epsilon-near-zero wavelength of the hyperbolic metastructure and ends at the point where plasmonic absorption appears strongly. It is observed that transmittance in the wavelength region longer than the IR cut-off band increases again due to plasmonic coupling among horizontally adjacent Ag nanopatterns. This metastructure can improve the performance of IR-blocking filters as well as allow it to be manufactured ultra-thin, which is applicable to various planar optical elements and integrated optical components.