• Journal of the Korean Mathematical Society
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• 제42권3호
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• pp.405-434
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• 2005

We establish appropriate $L^p$ estimates for a class of maximal operators $S_{\Omega}^{(\gamma)}$ on the product space $R^n\;\times\;R^m\;when\;\Omega$ lacks regularity and $1\;\le\;\gamma\;\le\;2.\;Also,\;when\;\gamma\;=\;2$, we prove the $L^p\;(2\;{\le}\;P\;<\;\infty)\;boundedness\;of\;S_{\Omega}^{(\gamma)}\;whenever\;\Omega$ is a function in a certain block space $B_q^{(0,0)}(S^{n-1}\;\times\;S^{m-1})$ (for some q > 1). Moreover, we show that the condition $\Omega\;{\in}\;B_q^{(0,0)}(S^{n-1}\;\times\;S^{m-1})$ is nearly optimal in the sense that the operator $S_{\Omega}^{(2)}$ may fail to be bounded on $L^2$ if the condition $\Omega\;{\in}\;B_q^{(0,0)}(S^{n-1}\;\times\;S^{m-1})$ is replaced by the weaker conditions $\Omega\;{\in}\;B_q^{(0,\varepsilon)}(S^{n-1}\;\times\;S^{m-1})\;for\;any\;-1\;<\;\varepsilon\;<\;0.$

• Journal of the Korea Academia-Industrial cooperation Society
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• 제18권6호
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• pp.366-374
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• 2017

This study was conducted to explore the degree of female nursing student's dietary behavior, self esteem, dietary self-efficacy, life stress and the factors influencing dietary behavior of those surveyed. A total of 422 female nursing students in B, C city were surveyed. The data were collected between May 15 and 30 of 2016 and analyzed by a t-test, ANOVA, Pearson's correlation coefficients, and multiple regression analysis using SPSS WIN/21.0. The mean score of dietary behavior was $3.01{\pm}0.49$. In addition, there were significant differences in dietary behavior with respect to grade(F=4.823, p=0.008), residential type(F=6.067, p<.001), academic grade(F=3.907, p=0.021), health status(F=7.975, p<0.001), and degree of health concern(F=4.189, p=0.016). Moreover, there were negative correlations between dietary behavior and self esteem(r=-.238, p<0.001), and dietary self-efficacy(r=-0.438, p<0.001), while there was a positive correlation between dietary behavior and life stress(r=0.194, p<0.001). Regression analysis showed 26.7% of variance in female nursing student's dietary behavior can be explained by dietary self-efficacy, life stress, residental type, and degree of health concern. A follow-up survey investigating various factors influencing female nursing student's dietary behavior is needed and increased dietary behavior education and programs are required.

• Journal of Microbiology and Biotechnology
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• 제14권3호
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• pp.547-552
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• 2004

Streptomyces thermovulgans malate synthase (stMS) is known to be more thermostable and thermoactive than S. coelicolor malate synthase (scMS). Therefore, based on the amino acid sequence of stMS, 3 scMS mutants, namely P186R, T8PL9P, and T8PL9PP186R, were created by site-directed mutagenesis in an attempt to engineer a more thermoactive and thermostable enzyme. An enzymatic analysis of the wild-type and mutant MS revealed that P186R and T8PL9PP186R were more thermoactive than the wild-type scMS and T8PL9P. Furthermore, all 3 mutants exhibited a greater thermo stability than scMS, thereby suggesting that both R186 and P8P9 can cause increased thermo stability in scMS.

• Journal of the Korean Chemical Society
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• 제36권3호
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• pp.460-465
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• 1992

The structure of th 5S rRNA isolated from Xanthomonas citri was determined by enzymatic and chemical degradation methods. It consists of 119 nucleotides and contains no modified nucleosides. As does the 5S rRNA of X. maltophilia, it contains an additional uridine residue on the 5'-terminus. The secondary structure of the 5S rRNA from X. citri was almost identical to the generalized models proposed by many other workers [De Wachter et al., Biochimie, 64, 311 (1982); Specht et al., Nucleic Acids Res., 18, 2215 (1990); Cho et al., Proceedings of the First Symposium on Biomolecules, p. 9 (1991)]. The secondary structure of 5S rRNA from X. citri consists of five helices, five loops and two bulges. This 5S rRNA has a uridine residue at position 66 as a bulge.

• Nonlinear Functional Analysis and Applications
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• 제28권4호
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• pp.943-956
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• 2023

Let p(z) be a polynomial of degree n and for any complex number 𝛽, let D_𝛽p(z) = np(z) + (𝛽 - z)p'(z) denote the polar derivative of the polynomial with respect to 𝛽. In this paper, we consider the class of polynomial $$p(z)=(z-z_0)^s \left(a_0+\sum\limits_{{\nu}=0}^{n-s}a_{\nu}z^{\nu}\right)$$ of degree n having a zero of order s at z₀, |z₀| < 1 and the remaining n - s zeros are outside |z| < k, k ≥ 1 and establish upper bound estimates for the maximum of |D_𝛽p(z)| as well as |p(Rz) - p(rz)|, R ≥ r ≥ 1 on the unit disk.

• Microbiology and Biotechnology Letters
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• 제33권2호
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• pp.96-105
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• 2005

For screening of autoregulator receptor gene from Streptomyces longwoodensis, PCR was performed with primers of receptor gene designed on the basis of amino acid sequences of autoregulator receptor proteins with known function. PCR products were subcloned into the BamHIsite of pUC19 and transformed into the E. coli $DH5{\alpha}$. The isolated plasmid from transformant contained the fragment of 100 bp, which was detected on $2\%$ gel after BamHI treatment. The insert, 100 bp PCR product, was confirmed as the expected internal segment of gene encoding autoregulator receptor protein by sequencing. Southern and colony hybridizations with the 100 bp fragment as a probe allowed to select a genomic clone of S. longwoodensis, pSLT harboring a 4.4 kb SphI fragment. Nucleotide sequencing analyses revealed a 651 bp open reading frame(ORF) were isolated protein showing moderate homology ($35{\sim}46\%$) with the ${\Gamma}$-butyrolactone autoregulator receptors from Streptomyces sp., and this ORF was named sltR The sltR/pET-17b plasmid was constructed to overexpress the recombinant SltR protein (rSltR) in E. coli BL21 (DE3)/pLysS, and the rSltR protein was purified to homogeneity by DEAE-Sephacel column chromatography, and DEAE-5PW chromatography (HPLC). The molecular mass of the purified rSltR protein was 55 kDa by HPLC gel-filtration chromatography and 28 kDa by SDS-PAGE, indicating that the rSltR protein is present as a dimer. A binding assay with tritium-labeled autoregulators revealed that the rSltR has clear binding activity with a A-factor type autoregulator as the most effective ligand.

• Journal of applied mathematics & informatics
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• 제42권3호
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• pp.539-548
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• 2024

Let R be a ring and P be a prime ideal of R. A mapping d : R → R is called a multiplicative derivation if d(xy) = d(x)y + xd(y) for all x, y ∈ R. In this paper, our main motive is to obtain the well-known theorem due to Posner in the ring R/P for generalized derivations associated with a multiplicative derivation defined by an additive mapping F : R → R such that F(xy) = F(x)y + xd(y), where d : R → R is a multiplicative derivation not necessarily additive. This article discusses the use of generalized derivations associated with a multiplicative derivation to investigate the commutativity of the quotient ring R/P.

• Journal of the korean academy of Pediatric Dentistry
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• 제34권1호
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• pp.99-105
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• 2007

In clinical practice, air bubbles trapped in the pit and fissure may increase early loss of sealing materials for fracture, wear and microleakage. The purpose of this investigation was to examine the bubble behavior of pit and fissure sealant. The 140 replicas made of epoxy resin were used to this experiment. Following conditioning, light-polymerized sealants were applied and then exposed to the light source. After stereoscopic examination of standarized specimen by grinding, bubble behavior was analysed. The results obtained were as follows; 1. Ultraseal $XT^{(R)}$ plus grops irrespective of using time were higher than groups of $Helioseal^{(R)}$ with clinpro tip and metal tip in the frequency of bubble(p<0.05), 2. Ultraseal $XT^{(R)}$ plus old group was more than $Clinpro^{(R)}$, Teethmate $F-l^{(R)}$ and $Helioseal^{(R)}$ with brush tip in the number of bubble under 200 magnified cross section(p<0.05). 3. The widest mean area of bubble was shown in the Teethmate $F-1^{(R)}$. 4. No statistically significant difference of the frequency and the site of bubble between $Clinpro^{(R)}$ and $Helioseal^{(R)}$ groups(p>0.05).

• Korean Journal of Fisheries and Aquatic Sciences
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• 제34권2호
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• pp.137-144
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• 2001

Sequences of partial 18S rDNA have been analyzed to elucidate genetic diversity of scallops collected around Korean sea, The scallops used in genetic comparison are Argopecten irradians concentricus, Amusium japonicum japonicum, Chlamys farreri farreri, Chlamys (Swiftopecten) swifti and Patinopecten yessoensis. The 18S rDNA sequences were aligned by Clustalx program. Phylogenetic tree was drawn by Treecon program, The scallops were divided into two groups-the Family Pectinidae containing A. japonicum japonicum and the Family Propeamussiidae containing Argopecten, Chlamys and Patinopecten genera. The Family Propeamussiidae was also divided into the Supergenera Aequipecten containing A. irradians concentricus and Supergenera Chlamys containing C. farreri farreri, C. swifti and P. yessoensis. The species of C. swifti was closer to the P. yessoensis rather than C. farreri farreri in respect to nuclear 18S rDNA sequence.

• The Korean Journal of Pain
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• 제35권4호
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• pp.423-432
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• 2022

Background: The decreased expression of mu-opioid receptors (MOR) in the amygdala may be a key molecular in chronic post-surgical pain (CPSP). It is known that miR-339-5p expression in the amygdala of a stressed rat model was increased. Analyzed by RNAhybrid, miR-339-5p could target opioid receptor mu 1 (oprm1) which codes MOR directly. So, the authors hypothesized that miR-339-5p could regulate the expression of MOR via targeting oprm1 and cause the effects to CPSP. Methods: To simulate perioperative short-term stress, a perioperative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception rat model was built. A pmiR-RB-REPORT^TM dual luciferase assay was taken to verify whether miR-339-5p could act on oprm1 as a target. The serum glucocorticoid level of rats was test. Differential expressions of MOR, GFAP, and pERK1/2 in each group of the rats' amygdala were tested, and the expressions of miR-339-5p in each group of rats' amygdalas were also measured. Results: Perioperative stress prolonged the recovery time of incision pain. The expression of MOR was down-regulated in the amygdala of rats in stress + incision (S + IN) group significantly compared with other groups (P < 0.050). miR-339-5p was up-regulated in the amygdala of rats in group S + IN significantly compared with other groups (P < 0.050). miR-339-5p acts on oprm1 3'UTR and take MOR mRNA as a target. Conclusions: Perioperative stress could increase the expression of miR-339-5p, and miR-339-5p could cause the expression of MOR to decrease via targeting oprm1. This regulatory pathway maybe an important molecular mechanism of CPSP.