• 한국작물학회:학술대회논문집
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• 한국작물학회 1992년도 춘계 학술대회지
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• pp.90-91
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• 1992

• Perspectives in Nursing Science
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• 제15권1호
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• pp.11-17
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• 2018

Purpose: Many Korean college students suffer from physical inactivity and mental health problems. However, it has not been sufficiently reported how this lack of exercise and health-related behavior affect their health. The present study was performed to identify the relationships among physical activity level, health-promoting behavior, and physiological variables in Korean undergraduate and graduate students. Methods: Participants were 115 undergraduate and graduate students from one university in Seoul. The Pearson's correlation analysis was performed using SPSS for Windows. Results: Physical activity level had significant positive correlations with health-promoting behavior (r=.32, p=.001) and exercise self-efficacy (r=.25, p=.008), and health-promoting behavior had a significant correlation with depression (r=-.33, p<.001) and exercise self-efficacy (r=.44, p<.001). Additionally, physical activity level had significant correlations with triglyceride (r=-.20, p=.034) and vitamin D (r=.20, p=.029) levels. The high density cholesterol level had significant negative correlations with systolic blood pressure (r=-.33, p<.001), diastolic blood pressure (r=-.29, p=.002), and vitamin D (r=-.20, p=.035) levels. Conclusion: Physical activity level or health-promoting behavior had significant relationships with the health status of college students. Strategies need to be developed to improve health-promoting behaviors among college students.

• Asian Pacific Journal of Cancer Prevention
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• 제15권16호
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• pp.6871-6879
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• 2014

Background: The purpose of this study was to evaluate the potential association of five (p.P47S, p.R72P, PIN3 Ins16bp, p.R213R and r.13494g>a) polymorphisms of TP53 with the risk of developing breast cancer in North Indian Punjabi population. Methods: We screened DNA samples of 200 sporadic breast cancer patients (197 females and 3 males) and 200 unrelated healthy, gender and age matched individuals for the polymorphisms. Results: For the p.P47S polymorphism, we observed the PP genotype in 99.5% of the patients and PS genotype in only 1 patient. All the controls had the wild type PP genotype. The frequency of RR, RP and PP genotype of p.R72P was 23.5% vs 33.5%, 51.5% vs 45.5% and 25% vs 21% in patients and controls respectively. Heterozygous (RP) genotype was increased in breast cancer patients as compared to controls (51.5 vs 45.5%) and showed 1.61 fold significantly increased risk for breast cancer (OR=1.61, 95% CI, 1.01-2.58, p=0.04). In breast cancer patients the frequencies of A1A1, A1A2 and A2A2 genotypes of PIN3 Ins16bp polymorphism were 67%, 26% and 7% respectively whereas in controls the genotype frequencies were 68.5%, 27.5% and 4% respectively, with no significant difference. For p.R213R (c.639A>G), all individuals had homozygous wild type genotype. The frequencies of GG, GA and AA genotypes of TP53 r.13494g>a polymorphism were 62 vs 67.5%, 33 vs 28% and 5 vs 4.5% in patients and controls respectively, again without significant difference. We observed that RP-A1A1 genotype combination of p.R72P and PIN3 Ins16bp and RP-GG combination of p.R72P and r.13494g>a polymorphism showed significant risk of breast cancer (OR=1.65, 95%CI: 0.98-2.78, p=0.05; OR=1.72, 95%CI: 1.01-2.92, p=0.04). Conclusion: The results of present study indicated that among the five TP53 polymorphisms investigated, the p.R72P polymorphism, and the RP-A1A1 and RP-GG genotype combination contribute to breast cancer susceptibility in North Indians.

• 대한간호학회지
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• 제33권6호
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• pp.856-864
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• 2003

Purpose: This study was to identify the relationships of trait anger, mode of anger expression, and perceived stress to mental health status in middle aged women. Method: The subjects were 157 middle aged women from 40s to 60s who lived in Seoul. Data was collected by questionnaire surveys using the convenience sampling. The instruments used for this study were Spielberger's trait anger scale and anger expression scale, Cohen, Kamarck, and Mermelstein's perceived stress and Derogatis's SCL-90-R. The collected data was analyzed using descriptive statistics, Pearson correlation coefficient, and Stepwise multiple regression with SAS/PC. Result: The trait anger of middle aged women indicated a significantly positive correlation to perceived stress(r=.180, p=.023) and mental health status(r.=021, p=.014). Anger-in(r=.237, p<.05), and perceived stress(p=.461, p<.01) showed significantly positive correlation to mental health status. The most significant predictor influencing health status of middle aged women was perceived stress, and anger-in and the variance explained was 27%. Conclusion: These results suggested that middle aged women with high degree of trait anger is likely to be high in stress perception. Perceived stress and anger-in are major factors influencing mental health status.

• Journal of Microbiology
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• 제44권1호
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• pp.35-41
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• 2006

The unique gene encoding thioredoxin reductase (TrxR) was previously cloned and characterized from the fission yeast Schizosaccharomyces pombe, and its expression was induced by oxidative stress. To elucidate tbe regulatory mechanism of the S. pombe TrxR gene, three fusion plasmids were generated using polymerase chain reaction: pYUTR20, pYUTR30, and pYUTR40. Plasmid pYUTR20 has an upstream region of 891 base pairs, pYUTR30 has 499 in this region, and pYUTR40 has an 186 bp upstream region. Negatively acting sequence is located between $-1,526\;\~\;-891bp$ upstream of the gene. The upstream sequence, responsible for the induction of TrxR by menadione (MD), is situated on the $-499\;\~\;-186bp$ region, which is also required for TrxR induction by mercuric chloride. The same region also appeared to be required for Pap1-mediated transcriptional regulation of the TrxR gene, which contains the two plausible Papl binding sites, TTACGAAT and TTACGCGA. Consistently, basal and inducible expression of the TrxR gene was markedly lower in the Pap1-negative TP108-3C cells than in wild-type yeast cells. In summary, up-regulation of the S. pombe TrxR gene is mediated by Pap1 via the transcriptional motif(s) located on the $-499\;\~\;-186bp$ region.

• Journal of Microbiology
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• 제40권1호
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• pp.43-50
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• 2002

A cluster of genes encoding the pyruvate dehydrogenase complex (PDC) of Streptomyces seoulensis, a Gram-positive bacterium, was cloned and sequenced. The genes of S. seoulensis consist of four open reading frames. The first gene, lpd, which encodes a lipoamide dehydrogenase, is followed by pdhB encoding a dihydrolipoamide acetyltransferase (E2p), pdhR, a regulatory gene, and pdhA encoding a pyruvate dehydrogenase component (Elp). Elp had an unusual homodimeric subunit, which has been known only in Gram-negative bacteria S. seoulensis E2p contains two lipoyl domains like those of humans and Streptomyces faecalis. The pdhR gene appears to be clustered with the structural genes of S. seoulensis PDC. The PdhR-overexpressed S. seoulensis howed growth retardation and the decrease of Elp, indicating that PdhR regulates the function of PDC by repressing the expression of Elp. A strain of Streptomyces licidans overexpressing S. seoulensis PdhR showed a significant decreasein the level of actinorhodin, implying a regulatory role for Streptomyces PDC in antibiotic biosynthesis.

• 가정∙방문간호학회지
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• 제26권1호
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• pp.64-71
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• 2019

Purpose: This study investigated the factors affecting spirituality in nursing students. Method: A total of 152 nursing students participated in the study. Data collection was conducted from October to November 2018. The data were analyzed using descriptive statistics, t-tests, analysis of variance, Pearson's correlation coefficient, and multiple stepwise regression via SPSS WIN 25.0. Results: The mean scores for empathy, gratitude, positive affect, negative affect, and spirituality were all average. However, there were significant differences in mean scores for spirituality according to satisfaction with major (F=5.88, p=.003), study grade (F=10.17, p<.001). Spirituality was found to be correlated with fantasy (r=.17, p<.001), empathic concern (r=.41, p<.001), perspective taking (r=.42, p<.001), personal distress (r=-.31, p<.001), gratitude (r=.65, p<.001), positive affect (r=.52, p<.001), and negative affect (r=-.30, p<.001). Significant predictors of spirituality included gratitude (${\beta}=.38$, p<.001), study grade (${\beta}=.34$, p=.009), positive affect (${\beta}=.29$, p<.001), and perspective taking (${\beta}=.16$, p=0.37), one of the sub-dimensions of empathy. Conclusion: To improve spirituality among nursing students, nursing educators should develop educational intervention programs to promote gratitude, study grades, positive affect, and perspective taking.

• 간호행정학회지
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• 제7권3호
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• pp.439-446
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• 2001

The purpose of this study was to identify the relationship of nursing service satisfaction and nurse's nursing activity styles in a hospital settings. The subjects of this study were 150 admitted patients in a hospital. The data was collected with Nursing Service Satisfaction Scale developed by Tomas(1996) and modified Nurse's Nursing activity styles Scale developed by Coeling(1993). The results were as follows: 1. The mean score for the level of nursing service satisfaction was 65.00(SD=14.10). The mean score for subcategories of nurse's nursing activity styles were as follow; work difficulties management 9.47(SD=2.02), effective work attitude 23.53(SD=3.14), interpersonal relationship 48.82(SD=6.18), keep regulation 23.24(SD=3.62), professional values 48.28(SD=5.27), and professional development 24.41(SD=3.07). 2. The correlations of nursing service satisfaction and subcategories of nurse's nursing activity styles were revealed a positive significant correlation; work difficulties management(r=0.17, p=0.03), effective work attitude(r=0.44, p=0.00), interpersonal relationship(r=0.51, p=0.00), keep regulation(r=0.44, p=0.00), professional values(r=0.31, p=0.00), professional development(r=0.30, p=0.00). 3. Stepwise multiple regression analysis revealed that the most powerful predictor of nursing service satisfaction was effective interpersonal relationship. A combination of effective work attitude, work difficulties management account for 38% of the variance in nursing service satisfaction of the patient in a hospital. In conclusion, this study revealed that the effective work attitude, interpersonal relationship, and work difficulties management in nursing activity were important factors to improve the level of nursing service satisfaction.

• 한국산학기술학회논문지
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• 제14권4호
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• pp.1755-1764
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• 2013

본 연구는 노인요양시설에 근무하는 간호사와 요양보호사의 직무관련 소진에 영향을 미치는 요인을 확인하기 위한 서술조사연구이다. 연구의 대상은 서울과 경기지역 소재 5개소 노인요양시설의 간호사 77명과 요양보호사 111명으로 구조화된 설문지를 이용하여 자료를 수집하였다. 수집된 자료는 IBM SPSS Statistics 19.0의 독립표본 t-test, Pearson's correlation coefficients, and multiple stepwise regression으로 분석하였다. 간호사의 직무관련 소진은 직무만족(r=.333, p=.003), 스트레스(r=.484, p<.001)와 양의 상관관계가 있었으며, 요양보호사의 직무관련 소진은 스트레스(r=.458, p<.001)와 양의 상관관계가 있는 것으로 나타났다. 간호사의 직무관련 소진에 영향을 미치는 요인은 대인관계 스트레스였으며 이는 간호사의 직무관련 소진의 27.0%를 설명하고 있었다. 요양보호사의 경우는 직무관련 스트레스로 나타났으며 이는 요양보호사의 직무관련 소진의 21.2%를 설명하고 있었다. 이와 같은 연구결과를 바탕으로 근무환경의 개선과 체계적인 스트레스 관리 프로그램의 개발이 이루어져야 할 것이다.

• 한국식품과학회지
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• 제33권2호
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• pp.195-199
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• 2001

Amylograph를 이용하여 방사선 조사된 검은후추가루의 amylograph characteristics의 변화를 검사하고, 변화된 amylograph characteristics에 의해서 검은후추가루의 검지가 가능한지를 알아보기 위하여 본 실험은 수행되었다. Initial pasting temperatures, maximum viscosity temperatures는 조사선량의 증가에 따른 유의적인 변화가 관찰되지 않았다. Maximum viscosity(P), $93^{\circ}C$ viscosity, $93^{\circ}C$에서 15분 후의 viscosity(H), $45^{\circ}C$ viscosity(C), $45^{\circ}C$에서 30분 후의 viscosity, $45^{\circ}C$에서 60분 후의 viscosity는 조사선량이 증가할수록 감소하는 경향을 보여주었으며, p<0.05의 수준에서 통계적인 유의성이 관찰되었다. 그러나 breakdown(P-H), setback(C-P), 그리고 consistency(C-H)는 조사선량의 증가에 따른 명확한 차이가 관찰되지 않았다. breakdown(P-H)이 0.75, setback(C-P)이 0.88, consistency(C-H)가 0.31의 $R^2$ 값을 보인 것을 제외하고는 모든 amylograph characteristics 의 $R^2$ 값은 0.97 이상의 높은 상관성을 보여 주었다. 따라서 amylograph characteristics에 의해서 검은후추가루의 방사선 조사여부 확인이 가능하였다.