• Journal of Korean Academy of Nursing
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• v.26 no.2
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• pp.467-482
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• 1996

This study was carried out to measure the degree of organizational commitment, job involvement, and role stress of clinical nurses, and to identify the relationships among personal characteristics, role stress, organizational commitment and job involvement in clinical nurses. The subjects were consisted of 412 nurses who were working at three General Hospitals in Chonbuk. The data were collected by self-reporting questionnaire from Sept. 20 to Sept. 31, 1995. The instruments used in this study were Organizational Commitment Scale developed by Mowday et al. and Job Involvement Scale developed by Kanungo. The role stress was measured by the scale developed by Rizzo( : role conflict, role ambiguity) and Beehr( : role overload). T-test, one-way ANOVA, Scheffe test and pearson's correlation coefficient were used for data ana1isis. Major findings were as follows : 1. Mean scores for organizational commitment were 3.008, job involvement 3.074, and role stress 2. 815( :role conflict 2.802, role ambiguity 2.253, role overload 3.294) on a 5 point scale. 2. All of personal characteristics were significantly related to the level of organizational commitment : age（r＝.481, p＝.000）, clinical experience（r＝ .479, p＝.000）, educational level（t＝4.11, p＝ .000）, position（F＝30.867, p＝.000）, marital status（t＝-5.63, p＝.000） and hospital agency （F＝21.374, p＝.000）. 3. All of personal characteristics were significantly related to the level of job involvement : age（r＝ .381, p＝.000）, clinical experience（r＝.393, p＝ .000）, educational level（t＝3.72, p＝.000）, position（F=18.004, p＝.000）, marital status（t＝-4. 91, p＝.000） and hospital agency（F=39.441, p＝ .000）. 4. There was a negative relationship between role stress and organizational commitment（r＝-.519, p＝.000）. 5. There was a negative relationship between role stress and job involvement（r＝-.256, p＝.000）. 6. There was a positive relationship between organizational commitment and job involvement （r＝.591, p＝.000）.

• Toxicological Research
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• v.31 no.1
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• pp.17-23
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• 2015

Excessive manganese (Mn) in the brain promotes a variety of abnormal behaviors, including memory deficits, decreased motor skills and psychotic behavior resembling Parkinson's disease. Hereditary hemochromatosis (HH) is a prevalent genetic iron overload disorder worldwide. Dysfunction in HFE gene is the major cause of HH. Our previous study has demonstrated that olfactory Mn uptake is altered by HFE deficiency, suggesting that loss of HFE function could alter manganese-associated neurotoxicity. To test this hypothesis, Hfe-knockout ($Hfe^{-/-}$) and wild-type ($Hfe^{+/+}$) mice were intranasally-instilled with manganese chloride ($MnCl_2$ 5 mg/kg) or water daily for 3 weeks and examined for memory function. Olfactory Mn diminished both short-term recognition and spatial memory in $Hfe^{+/+}$ mice, as examined by novel object recognition task and Barnes maze test, respectively. Interestingly, $Hfe^{-/-}$ mice did not show impaired recognition memory caused by Mn exposure, suggesting a potential protective effect of Hfe deficiency against Mn-induced memory deficits. Since many of the neurotoxic effects of manganese are thought to result from increased oxidative stress, we quantified activities of anti-oxidant enzymes in the prefrontal cortex (PFC). Mn instillation decreased superoxide dismutase 1 (SOD1) activity in $Hfe^{+/+}$ mice, but not in $Hfe^{-/-}$ mice. In addition, Hfe deficiency up-regulated SOD1 and glutathione peroxidase activities. These results suggest a beneficial role of Hfe deficiency in attenuating Mn-induced oxidative stress in the PFC. Furthermore, Mn exposure reduced nicotinic acetylcholine receptor levels in the PFC, indicating that blunted acetylcholine signaling could contribute to impaired memory associated with intranasal manganese. Together, our model suggests that disrupted cholinergic system in the brain is involved in airborne Mn-induced memory deficits and loss of HFE function could in part prevent memory loss via a potential up-regulation of anti-oxidant enzymes in the PFC.

• Journal of Korean Clinical Nursing Research
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• v.27 no.1
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• pp.45-53
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• 2021

Purpose: This study was conducted to assess the factors affecting turnover intention of the nurses working in neonatal intensive care units, including the extent of fatigue, work stresses, and work overload related to infection control. Methods: This was a descriptive correlational study to test factors affecting the turnover intention of the nurses working in neonatal intensive care units. Data was analyzed utilizing descriptive statistics, t-test, One-way ANOVA, Pearsons' Correlation Coefficient, and multiple regressions by using the IBM SPSS Statistics 23.0 Program(IBM Corp., Armonk, NY). Results: The turnover intention of nurses had a positive correlation with the extent of fatigue (r=.54, p<.001), work stress (r=.40, p<.001), and with the work overload (r=.43, p<.001) related to infection control. In addition, factors affecting the turnover intention of nurses included the extent of fatigue (β=.52, p<.001) related to infection control and the number of pediatric patients assigned to each nurse (β=.26, p=.001) and the variances explained by the regression model was 37.0%. Conclusion: It is necessary to establish and implement strategies to lower the extent of fatigue related to infection control by reducing the nurses' workload. Securing additional nurses to ensure an appropriate number of pediatric patients assigned to each nurse, and providing efficient management and available resources to reduce the turnover intention of nurses working in neonatal intensive care units are suggested.

• Journal of Ginseng Research
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• v.46 no.4
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• pp.515-525
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• 2022

Background: The incidence of ischemic cerebrovascular disease is increasing in recent years and has been one of the leading causes of neurological dysfunction and death. Ginsenoside Rg1 has been found to protect against neuronal damage in many neurodegenerative diseases. However, the effect and mechanism by which Rg1 protects against cerebral ischemia-reperfusion injury (CIRI) are not fully understood. Here, we report the neuroprotective effects of Rg1 treatment on CIRI and its possible mechanisms in mice. Methods: A bilateral common carotid artery ligation was used to establish a chronic CIRI model in mice. HT22 cells were treated with Rg1 after OGD/R to study its effect on [Ca²⁺]_i. The open-field test and poleclimbing experiment were used to detect behavioral injury. The laser speckle blood flowmeter was used to measure brain blood flow. The Nissl and H&E staining were used to examine the neuronal damage. The Western blotting was used to examine MAP2, PSD95, Tau, p-Tau, NOX2, PLC, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging was used to test the level of [Ca²⁺]_i. Results: Rg1 treatment significantly improved cerebral blood flow, locomotion, and limb coordination, reduced ROS production, increased MAP2 and PSD95 expression, and decreased p-Tau, NOX2, p-PLC, CN, NFAT1, and NLRP1 expression. Calcium imaging results showed that Rg1 could inhibit calcium overload and resist the imbalance of calcium homeostasis after OGD/R in HT22 cells. Conclusion: Rg1 plays a neuroprotective role in attenuating CIRI by inhibiting oxidative stress, calcium overload, and neuroinflammation.

• Fire Science and Engineering
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• v.24 no.2
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• pp.38-43
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• 2010

The purpose of this study is to secure the basis for judgment on the cause of an accident by analyzing the melting characteristics of a blade type fuse used for vehicles due to overload. In order to increase the reliability of the test, it was conducted by connecting the electrical system with conditions similar to those of an actual vehicle to apply the load. Carbonization pattern experiment of fuse by outside flame applied Korean Standard (KS). The fuse melted by the overcurrent showed a smooth cross-section while the test terminals, clear plastic body, etc., burnt out by the external flame was badly deformed. When 185% of the rated current (27.8A) was applied to a cable of 15A rated current onto which an over-capacity fuse (20A) was installed, the fuse melting time was 217 seconds. In addition, when a load current of 28.8[A] (139%) was applied, the fuse's test terminal and terminal blade were not burnt out although foam was observed on some parts of the plastic body. When a load capacity of 28.2[A] (141%) was applied to a cable of 15A rated current onto which an over-capacity fuse (30A) was installed, the fuse melting time was approximately 10 seconds. When a load current of 35.8[A] (119%) was applied, the fuse's test terminal and terminal blade were not burnt out, although some parts of the plastic body was swelled. However, it was observed that the switch terminal melted if approximately six minutes lapsed under such conditions. When a load capacity of 39.4[A] (131%) was applied to a cable of 15A rated current onto which an over-capacity fuse (30A) was installed, the fuse melted in approximately 69 seconds, and the test terminal and terminal blade were not burnt.

• Journal of the Korea institute for structural maintenance and inspection
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• v.7 no.1
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• pp.239-249
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• 2003

The bridges, which were built between 20 and 30 years ago in rural area, have to support unexpected overload caused by excessive amount of transportation. For these rural bridges, repairs and replacements are needed. To avoid the high cost of rehabilitation, the bridge rating must correctly report the present load-carrying capacity. Rating engineers use Allowable Stress Design (ASD), Load Factor Design (LFD), and Load Resistance Factor Design (LRFD) to evaluate the bridge load carrying capacity. In this paper, the load rating methods are introduced, and it is illustrated how to use the load test data from literature survey. Load test is conducted to the bridge that was built 30 years ago in rural area. From load test results, new maintenance strategy is suggested instead of the bridge replacement.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.14 no.9
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• pp.749-755
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• 2002

In order to develop a multi-type heat pump system with two indoor units of non-uniform capacities, the optimum refrigerant circuit was developed using capillary tubes. The refrigerant circuit was composed of four main parts, a heating circuit, a cooling circuit, a by-pass circuit and a balance circuit. The system characteristics of multi-type heat pump was investigated through the rating test and the reliability test, using the multi-type psy-chrometric calorimeter. The results of the rating test showed that the capacity of the multi-type heat pump was about 93% of the design value. In particular, the capacity of cooling single mode was about 13% higher than the design value, and the capacity of heating multi mode was about 5% higher than the design value. The reliability of the multi-type heat pump was verified by various reliability tests (overload, extension tube, freeze up, under/over charging, sweat, flood back). The optimal amount of refrigerant charge and compressor capacity were determined from the present work.

• Fire Science and Engineering
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• v.23 no.5
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• pp.196-205
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• 2009

Electric mosquito repellent mats can be ignited by damage of cables, partial disconnection, overload. tracking and so on. In this study, we examined the structure of mosquito repellent mat, positive temperature coefficient(PTC) thermistor, used for heating element and phenomenological characteristics of remains, obtained on the scene of fires. After reappearance ignition test of PTC thermistors, we did comparison analysis them. And we could confine that the feature of heating plate and the shape of bursting were same.

• Journal of Korean Academy of Nursing
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• v.25 no.4
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• pp.790-806
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• 1995

The present study examined the causal relationships among nurses' job environment /job characteristics(work overload, lack of autonomy, professional role conflict, interpersonal relationships), maturity, job stress, job satisfaction and turnover intention by constructing and testing a theoretial framework. Based on Katz and Kahn's (1978) theory of organizational open system and Kahn, Wolfe, Quinn, and Snoek's (1964) theory of stress, nurses' turnover intention, job satisfaction and job stress were conceived of as outcomes of the interplay between personal characteristics and work environment. Personal aspects associated with outcome variables included professional knowlege and skill, and maturity(challenge, commitment, control, responsibility). The work environment factors involved work overload, lack of autonomy, professional role conflict, and interpersonal relationships (social support). Three university hospitals located in Seoul were selected to participate. The total sample of 443 registered nurses represents a response rate of 96 percent. Linear structural relationships (LISREL) technique was used to test the fit of the proposed conceptual model to the data and to examine the causal relationships among variables. The result showed that both the proposed model and the modified model fit the data excellently, revealing considerable explanatinal power for job stress and job satisfaction. The explanatory power of turnover intention was relatively lower than those of stress and satisfaction. In predicting nurses' stress, satisfaction and turnover intention, the findings of this study clearly demonstrated that professional role conflict might be the most important variable of the all the environmental variables and personal characteristics. The results were dis-cussed, including directions for the future research and practical implications drawn from the research were suggested.

• Journal of the Korean Society of Safety
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• v.33 no.1
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• pp.73-80
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• 2018

According to the statistics publication of KOSHA, more than half of serious accidents at the construction sites were related to the temporary works and/or the temporary structures such as scaffoldings, shores, earth retaining walls, etc. The structural failures are occurred because of the overload acting on the structures or lack of performance of the one or more members of the structures. For the prevention of the collapse accidents relating to the temporary structures at the construction sites, we have to control construction processes not to occur the overload and also to control the performance and quality of each member of the temporary structures. MOLIT has amended the "Construction Technology Promotion Act" on Jan. 7th, 2015 to ensure the structural safety of the temporary structures. According to the Act, the designers of the construction design projects should check the structural integrity of the structures including the temporary structures and the construction companies have to let 'the Relative Professionals' confirm the structural integrity of temporary structures, the shores(${\geq}5m$ high) and the scaffolds(${\geq}31m$ high), before construction. Also, MOLIT has amended the "Regulation for Construction Technology Promotion Act" on Jul. 4th, 2016 for quality management and testing of temporary equipments. According th this regulation, the construction companies and supervisors should manage and test the temporary equipments before using them. In this paper, the standard drawings of the shores(< 5 m high) and the scaffolds(< 31 m high) and the amended "Business Guideline for Quality Management of Construction Work" are presented. As the result of this study, MOLIT noticed the amended "Business Guideline for Quality Management of Construction Work" on Jul. 1st, 2017.