• 한국과학교육학회지
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• 제37권5호
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• pp.859-877
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• 2017

과학 교육의 궁극적 목표인 학생들의 과학적 소양을 배양하는데 있어 이하 모델과 모델링이 차지하는 핵심적 역할을 고려할 때, 중등 과학 교사의 모델과 모델링에 대한 인식을 조사하는 것은 모델 기반 교수 학습을 실제 과학 수업에 적용하기 위한 토대를 마련하기 위해 필수적이라고 할 수 있다. 모델 기반 교수 학습이란 학생들이 자신의 모델을 생성(generating), 평가(evaluating), 수정(modifying)하는 모델링을 통해 과학적 내용 지식을 학습하고 나아가, 과학의 본성에 대한 바람직한 이해를 구축하도록 모델과 모델링 과정에 대하여 학습하는 것을 의미하며, 그러한 모델링 수업의 안내자로서 과학 교사는 모델과 모델링에 대하여 튼튼한 이해를 소유하여야 한다. 이에 본 연구자는 현재 학교 현장에서 과학 교과를 가르치는 50명의 중등 과학 교사를 대상으로, 10개의 개방형 문항을 사용하여 다음과 같은 두 가지 범주의 모델과 모델링에 대한 여러 측면의 인식, 첫째, 모델과 모델링에 대한 여러 측면의 이해, 즉 정의, 예시, 목적, 다양성, 변화성, 설계와 구성, 평가 기준, 둘째, 교수도구로서의 모델과 모델링 활용의 중요성과 교수 의사를 조사하였다. 수집된 자료에 대한 질적 분석을 통하여 다음과 같은 결론에 도달하였다. 첫째, 대부분의 과학 교사들은 모델이 갖는 교수도구로서의 기능적 측면에 집중하여, '실제의 단순화된 표상'이라는 모델 개념을 소유하지만, 과학 내용 전달 측면의 효용에만 집중하기 때문에, 과학에 있어서 모델과 모델링의 역할을 파악하지 못 하고 있다. 둘째, 대부분의 과학 교사들은 하나의 자연 현상을 표상하기 위해 다양한 모델이 구성될 수 있다는 사실과, 그러한 모델의 변화 가능성에 대하여 비교적 잘 인식하고 있으나, 모델의 설계와 구성이나 평가 기준 측면의 이해는 수정을 필요로 하는 제한적 수준에 머물러 있다. 셋째, 많은 교사들이 모델과 모델링에 대하여 가르치는 것의 중요성을 인식하지만, 여러 교육 과정 상의 현실적 어려움과, 교사의 지식 부족을 토로하여 모델과 모델링의 실제 현장 적용에 대해 부정적 시각을 견지하는 교사들이 상당하였다. 넷째, 물리, 화학, 지구과학 전공 교사들에 비하여, 생물 전공 교사들은 전공 또는 과목 의존적 이해의 양상, 즉 생물교과에 자주 등장하는 기능적, 실물 모델에 국한된 모델 개념을 소유하였고, 그러한 관점은 교수도구로서 모델과 모델링을 활용하는 것에 대한 부정적 견해로 나타나, 모델에 대한 지식과 신념 사이의 상호관련성이 일견 탐지되었다. 본 연구에서 중등 과학 교사들이 모델과 모델링에 대하여 무엇을 알고, 어떻게 가르치는가에 대한 기존의 인식을 탐색하여 분석한 결과는 과학 교사의 모델과 모델링에 대한 이해의 제고를 위한 적극적인 개입에 대하여 큰 시사점을 갖는다.

• 트랜스-
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• 제3권
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• pp.55-86
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• 2017

본 논문은 포스트 시네마 시대가 도래함에 따라 영화 매체에 대한 재사유와 동시대 영화들의 특정한 경향들을 포섭할 수 있는 개념이 필요하다는 자각에서 출발했다. 최근, 새롭게 등장한 도전적이면서 변화무쌍한 실험적인 영화들은 고전적인 미장센과 몽타주 분석만으로 접근하기 힘든 미학을 선보인다. 고전적 개념 틀로 분석하기가 곤혹스러운 영화들을 본고에서는 에이드리언 마틴이 제시한 디스포지티프 논의를 수용해서 고찰했다. 디스포지티프적 움직임은 디지털 테크놀로지가 기반이 되는 현대의 미디어 환경 속에서 급격히 늘어나긴 했지만 이 흐름이 어떤 특정한 시대에만 국한된 현상은 아니다. 일부 고전영화에서도 그 움직임이 감지됐으며 1920년대 아방가르드 영화들, 1960년대 모더니즘 영화들 일부에서 디스포지티프 경향은 계속 존재했었다. 영화적 디스포지티프의 명확한 개념화를 위해 본 논문은 오늘날 영화이론에 유입되고 있는 디스포지티프 논의의 근원을 살펴보았다. 하지만 인문학적 차원에서 논의되는 디스포지티프 이론은 분명 영화에서 거론되는 것과는 차이가 있다. 따라서 본고는 마틴의 노고로 가시화된 디스포지티프의 시네마틱한 요소를 부각시키면서 논의를 진행했다. 푸코가 정초한 디스포지티프의 기본적 의미는 이질적인 요소들로 구성된 장치의 배치와 배열이다. 때로는 이질적인 요소들의 앙상블 그 자체를 가리키기도 한다. 디스포지티프 논의를 촉발시켰던 푸코의 개념을 빌어 디스포지티프 영화를 정의한다면, 고전적 영화의 조건들을 구성하는 이질적 요소들의 재(탈)배치와 배열로 이루어진 새로운 '고안물(constraption)'이라고 할 수 있을 것이다. 어떤 것이 새로운 고안물이 되기 위해서는 그것을 이루는 요소들, 즉 힘들의 배열과 배치에 변화가 일어나야 한다. 당연히 그 요소들은 내적인 요소와 외적인 요소들을 아우른다. 내적인 요소는 주로 영화의 컨벤션에 대한 것이며 외적인 요소는 영화를 둘러싼 정치, 문화, 사회적인 조건과 영화를 가능하게 하는 광학적, 물리적 토대 모두를 포함한다. 영화는 어떤 매체보다도 빠른 속도로 다른 매체와 손쉽게 '네트워킹'하며 새롭게 '고안된' 미학 양식을 만들 수 있다. 상호매체성으로 정의되는 디지털 시대의 두드러진 특징을 디스포지티프 개념으로 바라본다면 영화뿐만 아니라 예술 전반에 걸쳐 발생하는 새로운 흐름들을 이해하는 데 도움이 될 것이다.

• 한국전통조경학회지
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• 제30권4호
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• pp.44-55
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• 2012

본 연구는 국내 서원 중 성리학적 사유와 규범에 가장 충일(充溢)하다고 알려진 도동서원을 대상으로 인간 중심의 성리학적 우주관의 핵심인 중용의 조형 미학적 특성이 서원의 경관짜임에 어떻게 투영되고 있는 가를 풀이하고자 하였다. 건축적 완성도와는 다른 관점에서, 도동서원의 경관상을 지배하고 있는 형식미와 내용미를 터잡기 길내기 건물놓기 시선모으기 담두르기 이름붙이기 꾸미기 등 총 7개의 경관짜임 항목을 기준으로 도동서원 조형에 담긴 중용의 미를 탐구한 결과는 다음과 같다. 외형적 짜임의 일부로서 도동서원의 좌향은 자연으로서의 방위를 인간 본위의 방위로서 중화(中和)시킴으로써, 인간과 자연의 일체감을 통한 중용지도(中庸之道)의 경지에 이르고자 하는 경관짜임 의지에서 비롯된 것으로 보인다. 도동서원의 외적 질서와 규범을 규정짓는 핵심적 요소로는 위계성과 좌우대칭을 바탕으로 한 계층성의 원리로 이는 어느 한쪽으로도 치우치지 않는 중용(中庸)의 정신이 관통함으로써 형성된 건물놓기와 길내기의 결합을 통한 경관짜임의 결과이다. 또한 담장두루기로 영역성을 확보하고 수직과 수평적 일체감을 이룸으로써 중용에 이르고자 한 경관짜임 또한 표출되고 있다. 그리고 서원의 중심 강당 마루에서 지각되는 수월루와 환주문의 지붕 중첩, 중정당 기둥에 의한 프레임에 의한 시각틀 형성 등을 통해 시각적 균형성과 개폐성을 유도하는 수법은 성리학적 조영 특유의 관념성을 드러내는 시선모으기의 경관짜임이다. 한편, 내용적 경관짜임의 일부로서 전신(前身)인 쌍계서원의 당호를 따른 관념적 이름붙이기, 성리학적 도(道)의 이동을 상징하는 서원명, 어느 한쪽으로도 치우치지 않는 중정(中正), 오륜에 근거한 거인재와 거의재 등의 건물 당호(堂號) 또한 중용의 미학을 준용한 결과이다. 그리고 중정당의 기단에 표현된 일음일양(一陰一陽) 변화를 나타내는 서화(瑞花)와 오르고 내리는 세호(細虎), 그리고 네 마리의 용으로 이루어진 사물 등은 지나침과 모자람이 없는 음양의 조화를 상징하는 중용의 예술적 표현이다. 이렇듯 도동서원은 좌우대칭과 계층화를 우선으로 한 상징 및 중용의 성리학적 질서와 규범의 정신으로 꽉 짜인 조직(組織)의 산물임이 확인된다. 그러나 도동서원이 엄정한 성리학적 세계관을 구현한 조형의 결과임은 분명하지만, 성리학적적 규범과 예법에만 충실했다면 그 평가는 그리 높지 않을 것이다. 도동서원 모든 영역에 고르게 배치된 해학적이고 독특한 석물과 돌조각 장식은 엄정해질 대로 엄정해진 서원 이미지와 외적 질서를 상쇄(相殺)시켜 '탈 엄정(脫 嚴整)'을 도모하기 위한 장치로써, 이는 또 다른 차원의 경관짜임이자 중용적 표현이라는 것은 매우 역설적이기까지 하다.

• 만화애니메이션 연구
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• 통권39호
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• pp.261-295
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• 2015

90년대 말에 등장한 사이버가수는 잠시 등장했다가 사라져 버렸고 2000년대 들어 몇 번의 시도는 있었지만 유의미한 성공사례를 보여주지 못하고 있다. 사이버가수는 대중음악계에서 아이돌 육성시스템의 등장과 IT산업의 기술발달에 힘입어 탄생하게 되었고 '아담'에서 시작해 보컬로이드 '시유'까지 개발되게 된다. 만화나 게임에 등장하는 일반적인 디지털캐릭터와 차별화되는 사이버가수는 음악을 매개로 하는 우상화의 대상이 될 수 있고 다수의 팬덤을 형성하는 특징을 가지고 있다. 따라서 실패를 거듭하고, 유행이 흘러간 컨텐츠로 간주될 수 있겠으나 보컬로이드 같은 새로운 매체를 활용해 지속적인 창작 시도를 하고 있어 진정한 사이버가수 탄생에 대한 기대가 존재한다고 볼 수 있다. 초창기 사이버가수는 인간의 외형만 닮아가려는 노력으로 진행되다가 사이아트와 시유에서 인간의 기능들을 닮아가는 것으로 진화되어 왔다. 본 논문은 과거 등장했다가 사라진 사이버가수가 단순히 실패사례로 끝나지 않고 나름의 인공생명체로 진화하려는 과정 속에서 기술을 발전시키고 기계이미지를 바라보는 대중의 인식변화를 조금씩 이끌었다는 점에서 의미 있는 시도였다고 본다. 더불어 그 진화의 방향성은 인간의 기능을 기계적으로 하나씩 획득하면서 인간과 상호 재미와 감정을 교류하면서 자신만의 외형과 기능을 갖춘 인공생명체로 진화하려는 모습을 갖추고 있다. 이런 논리를 뒷받침하기 위해 브루스 매즐리시의 인간과 기계의 공진화에 대한 연구를 참고했고 90년대 후반부터 등장했던 8개의 사이버가수들의 기획 및 디자인적인 캐릭터성과 가수로써 중요하게 평가되는 목소리(보컬)에 대한 발달과정을 브루스가 연구한 관점에서 사이버가수의 진화과정으로 분석했다. 기계는 인간과 함께 공진화하면서 진화해오고 있다. 사이버가수도 인간의 이데아적 욕망과 죽음에 대한 공포의 양가적 대상으로 인식되고 있지만 새로운 인공생명체가 되려는 개발노력은 지속되고 있다. 따라서 새로운 사이버생명체라면 시유 같은 스타일이 될 가능성이 높다. 왜냐하면 만화적 형태나 기계음 목소리가 인간이 실재 욕망하는 기표의 형태는 아닐 수 있으나 현시대의 대중이 원하는 욕망과 기술적 발달이 교차되는 지점에서 탄생할 수 있는 기표의 형태이기 때문이다.

• 헤리티지:역사와 과학
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• 제54권4호
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• pp.246-259
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• 2021

조선시대 지방 읍성에 대한 연구는 다방면에서 많은 성과가 있었으나, 그 내부 관청 건물의 하나인 옥(獄)에 대해서는 고고학적인 연구가 제대로 진행되지 않았다. 죄인들이 머무는 옥사의 배치나 구조, 옥리(관헌)들이 사무를 보거나 숙직 근무를 서는 집무소, 탈출을 방지하는 담장의 구조 등에 대해서는 1997년 경주에서 옥이 처음 발굴된 이후 연구의 필요성이 계속 제기되어 왔으나 비교 대상이 없어 답보 상태였다. 그러나 그 후 발굴된 연일옥 자료와 공주옥 등의 사진을 비교 분석해 본 결과 조선 전기부터 말기까지 축조된 옥의 구조를 파악할 수 있는 기초 자료를 확보할 수 있게 되었다. 세종은 전국의 죄수들을 잘 관리하도록 1426년 표준적인 설계도인 안옥도(犴獄圖)를 배포하였고, 동·하절기 처우 개선 등을 위해 1439년 한 차례 수정하기도 하였다. 1421년부터 1743년까지 운영된 연일옥은 조선 전기부터 중기까지의 옥의 구조를 파악할 수 있는데, 조선 후기까지 운영된 경주옥과 비교할 때 원형 담장, 동서 옥사의 배치와 구조 등 그 형식이 매우 유사하며 규모만 작을 뿐이다. 이러한 구조는 조선 말기 사진으로 남아 있는 공주옥까지 계속 그 형식이 유지되고 있음을 밝힐 수 있었다. 조선시대 옥은 타원형의 담장과 남녀를 구분하여 수용하는 건물이 나누어져 있었고, 담장의 높이는 약 3m에 이를 것으로 추정된다. 옥사는 동쪽이 남자, 서쪽이 여자 옥사로 구분되며 지붕으로 탈출이 어려운 기와집 구조였다. 원형 담장 앞에는 옥리(押牢)들이 근무하는 초가 지붕의 집무소가 있었는데, 2중의 옥문을 통해야만 옥의 출입이 가능하였다. 조선시대 왕들은 인본주의 유교 사상을 구현하고자 미결수들이 머무는 옥의 환경을 개선하고 남녀를 구분하여 수감토록 한 것이 건축물의 배치에 반영되었음을 알 수 있다.

• 벤처창업연구
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• 제13권6호
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• pp.1-14
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• 2018

명품에 대한 관심과 소비가 점차 대중화되면서 명품시장은 급성장하고 있다. 소비자들은 명품을 구매하고 사용함으로써 물질적인 풍요와 함께 심리적인 만족을 얻을 수 있다. 또한 기업의 입장에서는 명품은 가격 비탄력적인 특성을 가지고 있어 가격 프리미엄을 누릴 수 있고 양호한 성과를 산출하는데 유리하므로 명품성 확보방안에 많은 관심을 기울여야 할 것이다. 본 연구는 선행연구를 기반으로 명품성을 '다른 제품과 차별적으로 명품을 인식하게 만드는 제품의 속성으로서, 소비자의 구매행동에 중요한 동기를 부여하는 상황적 혜택을 제공하는 요인'으로 정의하고, 한국 중소기업의 브랜드 명품성 구축방안을 살펴보았다. 구체적으로는 명품산업의 세계시장과 한국시장 현황을 알아보고, 기존연구들과 관련문헌을 조사하여 명품성의 구성요소를 규명하였으며, 이론적 근거를 바탕으로 연구모형을 설계하여 마케팅 믹스를 활용한 한국 중소기업의 브랜드 명품성 구축방법을 제시하였다. 명품성의 하위차원은 기존연구들의 문제점을 감안하여 제품관련 속성여부와 소비자가 얻는 혜택여부에 따라 규명하였다. 제품관련 명품성은 우월성 (기능적 혜택)과 희소성(경험적 혜택)으로 구분하고, 비제품관련 명품성은 차별성 (상징적 혜택)과 전통성 (배타적 혜택)으로 구분하였다. 브랜드 명품성 구축방안은 다음과 같다. 첫째, 제품요인을 이용하는 것이다. 높은 품질, 우수한 디자인, 인지도가 높으면서 강력하고 호의적이며 독특한 연상의 브랜드를 통해 명품성을 제고할 수 있다. 둘째, 가격요인을 이용하는 것이다. 소비자들은 명품을 고가품으로 인식하는 경향이 있으므로 제품의 가격을 너무 낮게 책정하는 것은 명품성을 훼손할 수 있다. 셋째, 유통요인을 이용하는 것이다. 제한적인 유통 채널을 통해 소비자에게 명품성의 차별성과 희소성을 지각시키는 것이 효과적이다. 또한, 명품브랜드에 적합한 매장 분위기를 조성하여야 한다. 넷째, 촉진요인을 이용하는 것이다. 소비자가 광고에 많이 노출될수록 명품브랜드에 대해 호의적의 태도를 형성하여 명품성을 높게 지각한다. 가격촉진은 소비자의 명품성 지각에 부정적 영향을 미친다. 다섯째, 기업속성을 이용하는 것이다. 제품에 대한 소비자의 평가는 제품속성뿐만 아니라 그 제품을 둘러싼 기업연상이나 기업이미지에 영향을 받는다. 기존연구를 참고하면 높은 기업역량, 양호한 기업평판을 통해 명품성을 제고할 수 있다. 기업역량을 높이기 위해서는 지식창출능력과 연계하여 다차원적으로 접근하면 유용한 시사점을 얻을 수 있다. 기업평판에 있어서는 외부 이해관계자들의 평판도 중요하지만 이에 못지않게 내부구성원들의 평판도 중요하다. 한국의 중소기업들은 본 연구결과를 활용하여 상황에 따라 개별적인 마케팅전략을 수립하거나 혹은 믹스 (통합)한 마케팅전략을 수립하여 추진함으로써 브랜드의 명품성을 구축할 수 있을 것이다.

• 한국조경학회지
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• 제49권3호
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• pp.40-52
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• 2021

장백산은 시대마다 다양한 민족이 생활하였고, 시대별 민족들은 자신들만의 신앙문화로 장백산을 신성시 하였다. 기존의 장백산 문화에 대한 연구들은 특정 시대 사건에 관한 연구만 이루어지고 있는데, 정작 장백산의 신성성이 시대별로 어떻게 변천하고, 시대별 민족들의 신앙문화와 어떠한 관계가 있고, 어떻게 변하였는지에 대한 연구는 없었다. 본 연구는 장백산 신성성을 역사적 사료에 입각하여 시대적으로 변천해 온 의미를 고찰하고 분석하는 것이다. 장백산 신성성의 변천을 통시적으로 고찰하기 위하여 시대별 민족들의 신앙문화와 장백산 공간의 관계에서 발생하는 성현을 중심으로 고찰하였다. 구체적으로, 성현으로 드러난 신성한 공간을 보호하기 위한 활동을 고찰하였고, 도출된 결과를 가지고 장백산 신성성의 변천을 해석하였다. 본 연구의 결과를 요약하면 다음과 같다. 장백산 신성한 활동은 시대별로 다음과 같이 변천하였다. 청나라 이전 시대 민간들은 생계와 생존을 위한 화신제사, 성신제사, 산신제사, 버드나무신제사를 하였고, 금나라 왕은 악진(嶽鎭)과 같은 제사의례로 장백산신에게 제사를 드렸다. 청나라 시대 황제는 망제전을 조성하고 직접가거나 관원을 파견하여 국가를 상징하는 최고의 제사의례로 장백산신에게 제사를 드렸다. 근대는 장백산 정상에 팔괘묘를 조성하고, 장백산신에게 제사를 드리거나 팔괘의 술수를 통하여 장백산 자연과 장백산에서 생활하는 인간들의 길흉을 판단하였다. 또한 이 시기 민간들은 생활과 생산을 위하여 인격화 된 신 산신노파두를 중심으로 제사활동을 하였다. 정리하면, 장백산의 신성한 활동은 청나라 이전 시기는 애니미즘의 사상을 기본으로 한 샤머니즘 제사활동, 청나라 시기는 황실의 성산으로서 신성성을 받들기 위한 최고의 황실 제사의례, 근대시기는 이주민들의 도교사상을 기본으로 한 제사활동으로 변천하였다. 그리고 신성한 활동으로 바라 본 장백산의 의미는 청나라 이전 시대 생계의 산에서 청나라 시대 국가의 산으로 위상이 승격하였다가 근대 생산의 산으로 변화하였다.

• 한국과학예술포럼
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• 제34권
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• pp.327-337
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• 2018

최근 우리나라는 OECD 국가중 1위를 차지할 만큼 고령화사회로 고속화되고 있으며, 한국의 기대수명이 점차적으로 늘어감에 따라 사회에서 노인의 비중은 커져간다. 따라서 주요 노인계층의 행복감은 사회 전체적 분위기 및 행복감에 기여되는 부분이나 신체적, 심리적, 사회적 변화로 인한 노인의 삶의 질적 저하는 우울증, 자살률 증가 등의 사회적 문제로 발전될 수 있다. 이처럼 노인의 삶의 질과 만족도 향상에 대한 사회적 관심이 주어지면서, 경로당은 재가노인 사회활동의 중추적 역할을 담당할 수 있는 복지시설 형태로서 새롭게 주목받고 있다. 그러나 최근 경로당의 역할 부담의 증가로 인하여 노후된 환경개선에 노력을 기울이고 있으나, 물적 인적 자원의 한계로 인하여 정작 사용자를 배려한 실내환경의 질적 논란이 일고 있다. 색채환경은 사용자의 심리적, 정신적 영향이 높은 실내 환경인자일 뿐 아니라, 가장 저비용으로 환경만족도를 높일 수 있는 방안이라는 점에서 경로당 색채환경의 질 향상이 필요하다고 판단된다. 그러나 지금까지의 노인시설지침 중 색채환경에 대한 내용은 미비한 실정이며, 노인관련 시설에 대한 선행연구는 활발히 이루어져 왔으나, 산발적이므로 경로당 색채환경의 현주소 파악과 향후 개선방향의 도출을 위하여 관련 연구를 종합하여 체크리스트를 개발할 필요가 있다. 따라서 본 연구는 산재되어 있는 경로당 관련 법규 및 가이드라인과 경로당의 주 사용자인 노인의 특성(신체적, 심리적, 선호적) 관련 연구를 종합하여 체크리스트를 도출하며, 이는 경로당 색채환경의 평가도구로 사용될 수 있음을 기대한다. 경로당이 현재 전국적 네트워크를 가지는 주거영역에 기능하는 중요 노인여가시설이라는 점을 감안할 때, 본 연구의 결과는 향후 활성화될 기존의 경로당 환경개선을 보다 사용자인 노인의 심리적, 정신적 만족도 향상을 가능하게 하여 사회적으로 기여할 것으로 기대한다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.