• 대한조현병학회지
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• 제21권2호
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• pp.74-80
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• 2018

Objectives : This study investigated whether long-acting injectable (LAI) paliperidone is different from its oral form in terms of the effect on cognitive function in schizophrenia spectrum and other psychotic disorders. Methods : We reviewed the medical records of patients in Seoul National University Bundang Hospital who were diagnosed as having schizophrenia and/or other psychotic disorders based on DSM-5 from 2016 to 2017. Seven patients were treated with oral paliperidone and 11 were treated with paliperidone palmitate. All patients underwent clinical and neuropsychological assessment, including the Korean version of the MATRICS Consensus Cognitive Battery (MCCB) at their first visit or within one month of their initial treatment. MCCB was repeated within three to 12 months after the initial assessment. Results : There was no significant difference between the two groups in most cognitive domains including speed of processing, attention and vigilance, working memory, verbal learning, visual learning and reasoning and problem solving domain. However, patients treated with paliperidone palmitate showed better improvement in social cognition domain than those taking oral paliperidone. The standardized values of social cognition domain scores had significantly improved over time in patients under paliperidone palmitate, demonstrating a significant time-by-group interaction. Conclusion : Our results show that long-acting injectable paliperidone could be helpful in some aspects of improving cognitive function in schizophrenia spectrum and other psychotic disorders. Further studies with other antipsychotics are necessary to generalize the results.

• 치위생과학회지
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• 제11권3호
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• pp.257-263
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• 2011

본 연구는 노인의 구강 건강 향상의 방안으로 구강운동프로그램을 47명에 대하여 시행하여 39명의 대조군과 비교하여 다음과 같은 결과를 얻었다. 1. 타액분비량은 실험군이 0.075 ml로 대조군 0.046 ml 보다 0.029 ml 증가하여 구강운동으로 효과가 있는 것으로 나타났다. 2. 최대 개구량은 실험군이 4.12 cm로 대조군 3.92 cm 보다 0.20 cm 증가하여 구강운동으로 효과가 있는 것으로 나타났다. 3. 구강 교호 운동량은 실험군이 초당 1.69회에서 초당 2.03회보다 0.34회 증가하여, 구강운동으로 효과가 있는 것으로 나타났다. 이 결과 구강운동이 노인의 구강건강 뿐만 아니라 추후 구강운동을 고령화 시대 노인의 건강 증진 방안의 일환으로 적극 활용할 수 있도록 해야 할 것이다.

• Journal of Korean Dental Science
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• 제15권2호
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• pp.101-111
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• 2022

The purpose of laboratory tests in the field of oral medicine can be divided into two categories: (1) medical evaluation of patients with systemic diseases that are planning to receive dental care and (2) diagnosis of patients with certain oral diseases. First, laboratory tests are commonly used to evaluate patients with systemic diseases who need dental management. A combination of multiple tests is usually prescribed as a test panel to diagnose and assess a specific disease. Test panels closely related to oral medicine include those for rheumatoid arthritis, connective tissue disease/lupus, liver function, thyroid screening, anemia, and bleeding disorders. Second, laboratory tests are used as auxiliary diagnostic methods for certain oral diseases. They often provide crucial diagnostic information for infectious diseases caused by bacteria, fungi, and viruses that are associated with pathology in the oral and maxillofacial regions. Laboratory tests for infectious diseases are composed of growth-dependent methods, immunologic assays, and molecular biology. As the field develops, further application of laboratory tests, including synovial fluid analysis in temporomandibular joint disorders, salivary diagnostics, and hematologic biomarkers associated with temporomandibular disorders and orofacial pain conditions, is currently under scrutiny for their reliability as diagnostic tools.

• 대한치과보철학회지
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• 제37권1호
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• pp.23-41
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• 1999

During the previous several decades the osseointegrated implants have been considered as the most ideal therapy for the fully edentulous or partially edentulous patients. Although the research on the biocompatibility of osseointegration, the oral tactile function, and the histo-neurologic study had been performed, the change of the oral tactile sensibility and maximal occlusal force according to the postinsertion time of implant prostheses has not been studied. The purpose of this study was to compare the oral tactile sensibility and maximal occlusal force of implant pros-theses to natural teeth according to the specific postinsertion time intervals. The fifty seven patients treated with $Br{\aa}nemark$ implants during the recent seven years were involved in this study. The oral tactile sensibility and maximal occlusal force were measured according to the postinsertion time (${\leqq}6\;months,\;{\leqq}12\;{\leqq}\;18\;months\;{\leqq}\;24\;months,\;and\;{\geqq}20\;months$) 1. The passive tactile threshold of implants was higher than 6-7 times when comparing to natural teeth(P<0.05) 2. The absolute pressure threshold in horizontal and vertical direction for the passive tactile sensibility had decreased significantly in the post insertion time 13-18 months group and had increased significantly in the post insertion time over 25 months group (P<0.05) 3. 50% limit thickness and 100% absolute thickness for the active tactile sensibility had decreased significantly in the postinsertion time 7-12 months group ($AT_{50}:P<0.005,\;AT_{100}:P<0.05$) 4. The maximal occlusal force of the implants prostheses had decreased when comparing with natural teeth in the postinsertion time 1-6 months group(P<0.05) and after that there was no significant difference between the implant prostheses and natural teeth(P<0.05) 5. Maximal occlusal force according to the postinsertion time had increased significantly in the 13-18 months group (P<0.05) after that there was no significant difference. 6. There was positive correlation between age and oral tactile sensibility tested in horizontal and vertical direction ($P_{H:r}=0.39,\;P_{v:r}=0.41$) and there was no correlation between age and maximal occlusal force, age and active tactile sensibility 7. According to the results or the questionnaire, 76.6% of the patients were satisfied with the function and 96.7% of the patients were satisfied with the sensibility. In conclusion oral tactile sensibility and maximal occlusal force of implants have changed with the postinsertion time. Oral tactile function of implants was lower than that of the natural teeth, but for the maximal occlusal force there was no difference between implants and natural teeth.

• 보건의료생명과학 논문지
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• 제10권2호
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• pp.259-264
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• 2022

본 연구는 충청남도 홍성 지역에 거주하는 노인들을 대상으로 임플란트 의료보험 적용 시행 후 임플란트 전·후의 기능별 만족도 요인을 비교하여 노인들의 구강건강 관련 삶의 질을 향상하기 위한 기초자료를 제공하고자 하였다. 2020년 11월 1일부터 20211년 3월 31일까지 충청남도 홍성군에 거주하는 55세 이상을 대상으로 설문조사를 하였다. 저작, 사회적, 심리적 기능을 조사하여 Likert 5점 척도를 사용하였고 기능별 만족도 비교를 위해 paried T-test를 실시하였다. 임플란트 시술 전·후에 대한 저작 기능, 사회적 기능, 심리적 기능에 대한 모든 문항에서 임플란트 시술 전보다 시술 후에서 유의적으로 높게 나타났다(p<0.001). 임플란트 시술은 노인의 구강건강 뿐만 아니라 삶의 질 변화에도 많은 영향을 주므로 노인의 구강건강 증진을 위해서 노인들의 구강 건강 문제와 임플란트에 대한 연구가 더 많이 시행되고, 그에 따른 방안이 필요하겠다.

• Journal of Korean Dental Science
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• 제16권2호
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• pp.128-148
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• 2023

Dementia is an umbrella term that describes the loss of thinking, memory, attention, logical reasoning, and other mental abilities to the extent that it interferes with the activities of daily living. More than 50 million individuals worldwide live with dementia, which is expected to increase to 131 million by 2050. Recent research has shown that poor oral health increases the risk of dementia, while oral health declines with cognitive decline. In this narrative review, the literature was based on the "hypothesis" that dementia and oral health have a close relationship, and appropriate oral health and occlusal rehabilitation treatment can improve the quality of life of patients with dementia and prevent progression. We conducted a literature search in PubMed and Google Scholar databases, using the search terms "dementia," "major neurocognitive disorder," "dentition," "occlusion," "tooth loss," "dental prosthesis," "dental implant," and "occlusal rehabilitation" in the title field over the past 30 years. A total of 131 studies that scientifically addressed dementia, oral health, and/or oral rehabilitation were included. In a meta-analysis, the random effect model demonstrated significant tooth loss increasing the dementia risk 3.64-fold (pooled odds ratio=3.64, 95% confidence interval [2.50~5.32], P-value=0.0348). Tooth loss can be an important indicator of cognitive function decline. As the number of missing teeth increases, the risk of dementia increases. Loss of teeth can lead to a decrease in the ascending information to the brain and reduced masticatory ability, cerebral blood flow, and psychological atrophy. Oral microbiome dysbiosis and migration of key bacterial species to the brain can also cause dementia. Additionally, inflammation in the oral cavity affects the inflammatory response of the brain and the complete body. Conversely, proper oral hygiene management, the placement of dental implants or prostheses to replace lost teeth, and the restoration of masticatory function can inhibit symptom progression in patients with dementia. Therefore, improving oral health can prevent dementia progression and improve the quality of life of patients.

• 디지털융복합연구
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• 제12권4호
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• pp.399-407
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• 2014

본 연구는 노인의 의치 관련 특성, 의치 만족도, 구강건강관련 삶의 질 간의 관계를 분석함으로써, 향후 노인의 구강건강 증진과 삶의 질 향상을 위한 기초자료를 마련하고자 한다. 경북지역 안동시, 영주시, 의성군에 거주하는 65세 이상 노인을 대상으로 2013년 3월 25일부터 5월 9일까지 설문조사를 실시하였다. 연구결과 의치만족도는 의치고정만족, 발음심미만족, 저작기능만족 서로 높은 상관관계가 나타났고, 노인의 의치관련 특성, 의치만족도, 구강건강관련 삶의 질 간에 인과관계가 있는 것으로 나타났다. 따라서 효과적인 의치사용과 관리를 위한 노인구강보건교육과 노인 구강건강상태 인식수준을 향상 시킬 수 있는 제도적 및 방안이 마련되어야 할 것이다.

• 한국융합학회논문지
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• 제11권6호
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• pp.341-347
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• 2020

본 연구는 한국 표준직업분류에 따른 근로자의 구강기능문제를 파악하고 근로자들이 집단구강건강관리사업의 혜택을 받을 수 있도록 산업안전보건법의 개정을 촉구하기 위한 근거자료로 제공하고자 시행하였다. 국민건강영양조사 제7기 원시자료(1차,2차)를 이용하여 만 19세 이상 한국 표준직업분류에 따른 근로자를 대상으로 씹기문제와 말하기문제를 조사한 결과 한국 표준직업분류에 따른 근로자의 유형과 씹기문제, 말하기문제의 연관성이 확인되었다(p<0.05). 이에 근로자의 구강건강을 향상시키기 위해서는 집단구강건강관리사업이 실행되어야 하며 집단구강건강관리사업의 주최가 될 전문성을 갖춘 전문보건의료관리자를 채용할 수 있도록 산업안전보건법이 개정되어야 할 것이다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제31권1호
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• pp.82-88
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• 2005

Treatment methods of mandibular condylar fracture were conservative and surgical method. Surgical method of mandibular high condylar fracture was very difficult because approach and internal fixation of small size fracture fragment were difficult. So there is a tendency to select conservative method over surgical method for guiding a stable occlusion and avoiding TMJ disorder and growth disturbance, minimizing pain and deviation during function. But, in case of mandibular high condylar fracture patient who has no biting teeth on posterior teeth area, guiding a stable occlusion and conservative functional treatment were very difficult. In this case, patient was 62years old male. He had fracture of mandibular symphysis, right mandibular body, left mandibular high condyle. We treated the patient for mandibular symphysis and right mandibular body fracture area with surgical method. But left mandibular high condylar fracture area was difficult to treat with surgical method. So we selected a conservative functional method on left mandibular high condylar fracture area. We intended recovery of vertical dimension and stable occlusion with implantation of immediate provisional implant on maxillar and mandibular posterior teeth area, and temporary crown. And then patient did mandibular functional movement and his mandibular function was recoverd.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제28권6호
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• pp.472-479
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• 2002

Since $Br^{\circ}anemark$ introduced the osseointegrated implants, they have been granted for useful methods for the restoration of oral function. The original $Br^{\circ}anemark$ protocol recommended long stress-free healing periods to achieve the osseointegration of dental implants. However, many clinical and experimental studies have shown that the osseointegration is no wonder in almost cases and that early and immediate loading may lead to predictable osseointegration. So we are willing to introduce the Satellite Abutment newly invented for immediate loading. We think that it will make the occlusal forces dispersed to surrounding bone and that we can restore the oral function immediately after implant installation not disturbing osseointegration. In case of using Satellite abutment, stress concentrated to bone contact area of implant was distributed not only fixation plate and screws but also superior, middle portion of implant and cortical layer of jaw bone. It was clearly decreased on the bone contact surfaces around dental implants. 1. Stress was decreased more than 76.5% when satellite straight abutment was used. 2. Stress was decreased more than 50% when satellite angled abutment was used. 3. The stress around dental implant was well distributed along the cortical bone surface and the fixation plate and screw. This study concludes that satellite abutment can be used as all immediate loading implant prothesis because it was possible to distribute periimplant occlusal stress through implant contact bone surface and cortical layer of jaw bone.